DK1709057T3 - Syntese af spongosin - Google Patents

Syntese af spongosin

Info

Publication number: DK1709057T3
Authority: DK; Denmark
Prior art keywords: synthesis; spongosine; methoxyadenine; benzoyl; tri
Prior art date: 2004-01-21

Application number

DK05701948T

Other languages

English (en)

Inventor

Jacqueline Valerie Anne Ouzman

Original Assignee

Cambridge Biotechnology Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-21

Filing date

2005-01-19

Publication date

2008-04-28

2005-01-19 Application filed by Cambridge Biotechnology Ltd filed Critical Cambridge Biotechnology Ltd

2008-04-28 Application granted granted Critical

2008-04-28 Publication of DK1709057T3 publication Critical patent/DK1709057T3/da

Links

AJACDNCVEGIBNA-KQYNXXCUSA-N (2r,3r,4s,5r)-2-(6-amino-2-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound C12=NC(OC)=NC(N)=C2N=CN1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O AJACDNCVEGIBNA-KQYNXXCUSA-N 0.000 title abstract 3
AJACDNCVEGIBNA-UHFFFAOYSA-N 2-Methoxyadenosine Natural products C12=NC(OC)=NC(N)=C2N=CN1C1OC(CO)C(O)C1O AJACDNCVEGIBNA-UHFFFAOYSA-N 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title abstract 3
238000003786 synthesis reaction Methods 0.000 title abstract 3
NZRGFQAPUIYXEP-ZYWWQZICSA-N [(2r,3r,4r,5r)-5-(6-amino-2-methoxypurin-9-yl)-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1OC(=O)C=1C=CC=CC=1)OC(=O)C=1C=CC=CC=1)N1C=NC2=C(N)N=C(N=C21)OC)OC(=O)C1=CC=CC=C1 NZRGFQAPUIYXEP-ZYWWQZICSA-N 0.000 abstract 2
TUDKBZAMOFJOSO-UHFFFAOYSA-N 2-methoxy-7h-purin-6-amine Chemical compound COC1=NC(N)=C2NC=NC2=N1 TUDKBZAMOFJOSO-UHFFFAOYSA-N 0.000 abstract 1
GCZABPLTDYVJMP-CBUXHAPBSA-N [(2r,3r,4r,5s)-5-acetyloxy-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1OC(=O)C=1C=CC=CC=1)OC(=O)C=1C=CC=CC=1)OC(=O)C)OC(=O)C1=CC=CC=C1 GCZABPLTDYVJMP-CBUXHAPBSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000010511 deprotection reaction Methods 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Silicon Polymers (AREA)
Catalysts (AREA)

DK05701948T 2004-01-21 2005-01-19 Syntese af spongosin DK1709057T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0401292.8A GB0401292D0 (en)	2004-01-21	2004-01-21	Synthesis of spongosine
PCT/GB2005/000183 WO2005070947A1 (en)	2004-01-21	2005-01-19	Synthesis of spongosine

Publications (1)

Publication Number	Publication Date
DK1709057T3 true DK1709057T3 (da)	2008-04-28

Family

ID=31971211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05701948T DK1709057T3 (da)	2004-01-21	2005-01-19	Syntese af spongosin

Country Status (18)

Country	Link
US (1)	US20100216991A1 (da)
EP (1)	EP1709057B1 (da)
JP (1)	JP2007518782A (da)
KR (1)	KR20060132910A (da)
CN (1)	CN1910194B (da)
AT (1)	ATE381572T1 (da)
AU (1)	AU2005206361A1 (da)
CA (1)	CA2552552A1 (da)
CY (1)	CY1108048T1 (da)
DE (1)	DE602005003922T2 (da)
DK (1)	DK1709057T3 (da)
ES (1)	ES2298998T3 (da)
GB (1)	GB0401292D0 (da)
NO (1)	NO20063715L (da)
NZ (1)	NZ548220A (da)
PL (1)	PL1709057T3 (da)
PT (1)	PT1709057E (da)
WO (1)	WO2005070947A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20070004792A (ko) *	2004-03-05	2007-01-09	캠브리지 바이오테크놀로지 리미티드	아데노신 수용체 작용제
WO2014068589A2 (en) *	2012-10-29	2014-05-08	Biophore India Pharmaceuticals Pvt. Ltd.	Novel process for the preparation of (1-{9-[(4s, 2r, 3r, 5r)-3, 4-dihydroxy-5-(hydroxymethyl) oxolan-2-yl)-6-aminopurin-2-yl} pyrazole-4-yl)-n-methylcarboxamide
CN103342727A (zh) *	2013-07-01	2013-10-09	淮海工学院	一种2-甲氧基腺苷的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030008841A1 (en) *	2000-08-30	2003-01-09	Rene Devos	Anti-HCV nucleoside derivatives

2004
- 2004-01-21 GB GBGB0401292.8A patent/GB0401292D0/en not_active Ceased
2005
- 2005-01-19 EP EP05701948A patent/EP1709057B1/en not_active Expired - Lifetime
- 2005-01-19 KR KR1020067016484A patent/KR20060132910A/ko not_active Ceased
- 2005-01-19 NZ NZ548220A patent/NZ548220A/en unknown
- 2005-01-19 WO PCT/GB2005/000183 patent/WO2005070947A1/en not_active Ceased
- 2005-01-19 AT AT05701948T patent/ATE381572T1/de active
- 2005-01-19 PT PT05701948T patent/PT1709057E/pt unknown
- 2005-01-19 ES ES05701948T patent/ES2298998T3/es not_active Expired - Lifetime
- 2005-01-19 JP JP2006550274A patent/JP2007518782A/ja active Pending
- 2005-01-19 US US10/586,558 patent/US20100216991A1/en not_active Abandoned
- 2005-01-19 CN CN200580003003XA patent/CN1910194B/zh not_active Expired - Fee Related
- 2005-01-19 DE DE602005003922T patent/DE602005003922T2/de not_active Expired - Lifetime
- 2005-01-19 AU AU2005206361A patent/AU2005206361A1/en not_active Abandoned
- 2005-01-19 DK DK05701948T patent/DK1709057T3/da active
- 2005-01-19 CA CA002552552A patent/CA2552552A1/en not_active Abandoned
- 2005-01-19 PL PL05701948T patent/PL1709057T3/pl unknown
2006
- 2006-08-18 NO NO20063715A patent/NO20063715L/no not_active Application Discontinuation
2008
- 2008-03-07 CY CY20081100268T patent/CY1108048T1/el unknown

Also Published As

Publication number	Publication date
AU2005206361A1 (en)	2005-08-04
DE602005003922D1 (de)	2008-01-31
CN1910194A (zh)	2007-02-07
DE602005003922T2 (de)	2008-12-04
CY1108048T1 (el)	2013-09-04
JP2007518782A (ja)	2007-07-12
ES2298998T3 (es)	2008-05-16
GB0401292D0 (en)	2004-02-25
NZ548220A (en)	2009-12-24
CN1910194B (zh)	2010-05-05
CA2552552A1 (en)	2005-08-04
US20100216991A1 (en)	2010-08-26
PL1709057T3 (pl)	2008-05-30
NO20063715L (no)	2006-08-18
KR20060132910A (ko)	2006-12-22
EP1709057B1 (en)	2007-12-19
ATE381572T1 (de)	2008-01-15
EP1709057A1 (en)	2006-10-11
HK1099026A1 (zh)	2007-08-03
WO2005070947A1 (en)	2005-08-04
PT1709057E (pt)	2008-03-10

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