ATE382337T1 - Bioabsorbierbare pharmazeutische zusammensetzung enthaltend einen plga-copolymer - Google Patents
Bioabsorbierbare pharmazeutische zusammensetzung enthaltend einen plga-copolymerInfo
- Publication number
- ATE382337T1 ATE382337T1 AT06008539T AT06008539T ATE382337T1 AT E382337 T1 ATE382337 T1 AT E382337T1 AT 06008539 T AT06008539 T AT 06008539T AT 06008539 T AT06008539 T AT 06008539T AT E382337 T1 ATE382337 T1 AT E382337T1
- Authority
- AT
- Austria
- Prior art keywords
- molecular weight
- less
- release
- fraction content
- base material
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 title abstract 3
- 229920001577 copolymer Polymers 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 3
- 238000009472 formulation Methods 0.000 abstract 1
- 238000005227 gel permeation chromatography Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005131893 | 2005-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382337T1 true ATE382337T1 (de) | 2008-01-15 |
Family
ID=36952555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06008539T ATE382337T1 (de) | 2005-04-28 | 2006-04-25 | Bioabsorbierbare pharmazeutische zusammensetzung enthaltend einen plga-copolymer |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7342048B2 (de) |
| EP (1) | EP1716847B1 (de) |
| AT (1) | ATE382337T1 (de) |
| DE (1) | DE602006000381T2 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7763769B2 (en) * | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
| WO2007084460A2 (en) | 2006-01-18 | 2007-07-26 | Qps, Llc | Pharmaceutical compositions with enhanced stability |
| WO2012082765A2 (en) | 2010-12-16 | 2012-06-21 | The United State Of America. As Represented By The Secretary Department Of Health And Human Services | Methods for decreasing body weight and treating diabetes |
| JP6204345B2 (ja) | 2011-03-23 | 2017-09-27 | ザ・ユナイテッド・ステイツ・オブ・アメリカ・アズ・リプリゼンティド・バイ・ザ・セクレタリー・フォー・ザ・デパートメント・オブ・ヘルス・アンド・ヒューマン・サービシズ | 幹細胞の多能性を高めるための組成物及び方法 |
| US8637038B2 (en) | 2011-04-12 | 2014-01-28 | Rigel Pharmaceuticals, Inc. | Methods for inhibiting allograft rejection |
| US9932560B2 (en) | 2011-05-13 | 2018-04-03 | Elixirgen, Llc | Use of Zscan4 and Zscan4-dependent genes for direct reprogramming of somatic cells |
| US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| EP3782628B1 (de) | 2013-03-15 | 2024-08-07 | Elixirgen Therapeutics, Inc. | Verfahren zur verwendung von zscan4 zur verjüngung menschlicher zellen |
| KR102233251B1 (ko) | 2013-04-03 | 2021-03-26 | 엔-폴드 엘엘씨 | 신규 나노입자 조성물 |
| AU2014340241B2 (en) | 2013-10-21 | 2018-11-01 | Salk Institute For Biological Studies | Mutated fibroblast growth factor (FGF) 1 and methods of use |
| MX2016011517A (es) | 2014-03-07 | 2017-04-13 | Univ Arizona | Peptidos de crmp2 no narcoticos que seleccionan como diana canales de sodio para el dolor cronico. |
| WO2018160772A1 (en) | 2017-02-28 | 2018-09-07 | The United State Of America, As Represented By The Secretary, Department Of Health & Human Services | Method of treating obesity, insulin resistance, non-alcoholic fatty liver disease including non-alcoholic steatohepatitis |
| EP3775236A1 (de) | 2018-04-12 | 2021-02-17 | Krystal Biotech, LLC | Zusammensetzungen und verfahren zur behandlung von autosomaler rezessiver kongenitaler ichthyose |
| AU2019346549B2 (en) | 2018-09-24 | 2024-09-12 | Krystal Biotech, Inc. | Compositions and methods for the treatment of Netherton Syndrome |
| CA3266235A1 (en) | 2018-09-26 | 2025-11-29 | Krystal Biotech, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES |
| WO2020072805A1 (en) | 2018-10-04 | 2020-04-09 | Rutgers, The State University Of New Jersey | Methods of reducing type 2 cytokine-mediated inflammation using neuromedin peptides |
| EP3921334A1 (de) | 2019-02-08 | 2021-12-15 | Krystal Biotech, Inc. | Zusammensetzungen und verfahren zur verabreichung von cftr-polypeptiden |
| WO2020186187A1 (en) | 2019-03-13 | 2020-09-17 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods for treating bladder and urethra dysfunction and disease |
| CA3149164A1 (en) | 2019-09-03 | 2021-03-11 | Suma Krishnan | Compositions and methods for the treatment of congenital ichthyoses |
| CN110882222B (zh) * | 2019-12-05 | 2021-12-03 | 北京博恩特药业有限公司 | 颗粒组合物及制备方法和应用 |
| CA3160199A1 (en) | 2019-12-20 | 2021-06-24 | Suma Krishnan | Compositions and methods for gene delivery to the airways and/or lungs |
| CN111658620B (zh) * | 2020-04-30 | 2022-04-19 | 天津医科大学口腔医院 | 一种透明质酸-帕瑞昔布plga微球及其制备方法和应用 |
| WO2021225781A2 (en) | 2020-05-07 | 2021-11-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aberrant post-translational modifications (ptms) in methyl- and propionic acidemia and a mutant sirtuin (sirt) to metabolize ptms |
| BR112023020209A2 (pt) | 2021-04-02 | 2023-12-19 | Krystal Biotech Inc | Genoma do vírus do herpes recombinante, vírus do herpes, composição farmacêutica, uso do vírus do herpes ou da composição farmacêutica, método para expressar, realçar, aumentar, ampliar e/ou suplementar os níveis de um polipeptídeo imunomodulatório, método para prover alívio profilático, paliativo ou terapêutico, e, método para tratar câncer |
| AU2024229184A1 (en) | 2023-03-02 | 2025-08-28 | Krystal Biotech, Inc. | Interleukin-2 and interleukin-12 for cancer therapy |
| WO2024214081A1 (en) | 2023-04-13 | 2024-10-17 | Krystal Biotech, Inc. | Methods and compositions for the treatment of conditions involving the eye |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4328204A (en) * | 1977-03-02 | 1982-05-04 | Ethicon, Inc. | Absorbable polymer-drug compounds and method for making same |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| JPS60181029A (ja) | 1984-02-29 | 1985-09-14 | Toyo Jozo Co Ltd | 徐放性製剤の製法 |
| JPH0678425B2 (ja) | 1984-07-06 | 1994-10-05 | 和光純薬工業株式会社 | 重合体の新規製造法 |
| JP3168263B2 (ja) | 1984-07-06 | 2001-05-21 | 和光純薬工業株式会社 | 新規重合体及びこれを用いた医薬 |
| CA1256638A (en) * | 1984-07-06 | 1989-06-27 | Motoaki Tanaka | Polymer and its production |
| JP2551756B2 (ja) * | 1985-05-07 | 1996-11-06 | 武田薬品工業株式会社 | ポリオキシカルボン酸エステルおよびその製造法 |
| GB8609537D0 (en) * | 1986-04-18 | 1986-05-21 | Ici Plc | Polyesters |
| JP2653255B2 (ja) | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
| DE69129770T2 (de) * | 1990-04-13 | 1998-11-19 | Takeda Chemical Industries Ltd | Biologisch abbaubare hochmolekulare Polymere, ihre Herstellung und ihre Verwendung |
| JP3254449B2 (ja) | 1990-04-13 | 2002-02-04 | 武田薬品工業株式会社 | 生体内分解型高分子重合物 |
| TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| US5614390A (en) | 1996-06-14 | 1997-03-25 | Becton, Dickinson And Company | Species-specific detection of Mycobacterium kansasii |
| PT839525E (pt) * | 1996-10-31 | 2004-10-29 | Takeda Chemical Industries Ltd | Preparacao de libertacao prolongada |
| TR200002059T2 (tr) | 1998-01-16 | 2001-01-22 | Takeda Chemical Industries, Ltd. | Devamlı salınan bileşim, üretim yöntemi ve kullanımı. |
| CN1269870C (zh) * | 2000-08-07 | 2006-08-16 | 和光纯药工业株式会社 | 乳酸聚合物及其制备方法 |
| JP2004155792A (ja) | 2001-06-29 | 2004-06-03 | Takeda Chem Ind Ltd | 徐放性組成物およびその製造法 |
| JP3902518B2 (ja) | 2001-06-29 | 2007-04-11 | 武田薬品工業株式会社 | 徐放性組成物用乳酸−グリコール酸重合体の製造法 |
| TWI225416B (en) * | 2001-06-29 | 2004-12-21 | Takeda Chemical Industries Ltd | Sustained-release composition and process for producing the same |
| JP5188670B2 (ja) | 2001-06-29 | 2013-04-24 | 武田薬品工業株式会社 | 徐放性組成物およびその製造法 |
-
2006
- 2006-04-25 AT AT06008539T patent/ATE382337T1/de active
- 2006-04-25 EP EP06008539A patent/EP1716847B1/de not_active Expired - Lifetime
- 2006-04-25 US US11/411,193 patent/US7342048B2/en not_active Expired - Lifetime
- 2006-04-25 DE DE602006000381T patent/DE602006000381T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006000381D1 (de) | 2008-02-14 |
| US20060246139A1 (en) | 2006-11-02 |
| EP1716847A1 (de) | 2006-11-02 |
| DE602006000381T2 (de) | 2008-12-18 |
| US7342048B2 (en) | 2008-03-11 |
| EP1716847B1 (de) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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