NO20071853L - Farmasoytisk sammensetning inneholdende en fast dispersjon med en polymermatriks inneholdende en jevn polydekstrosefase og en jevn fase av en polymer forskjellig fra polydekstrose. - Google Patents
Farmasoytisk sammensetning inneholdende en fast dispersjon med en polymermatriks inneholdende en jevn polydekstrosefase og en jevn fase av en polymer forskjellig fra polydekstrose.Info
- Publication number
- NO20071853L NO20071853L NO20071853A NO20071853A NO20071853L NO 20071853 L NO20071853 L NO 20071853L NO 20071853 A NO20071853 A NO 20071853A NO 20071853 A NO20071853 A NO 20071853A NO 20071853 L NO20071853 L NO 20071853L
- Authority
- NO
- Norway
- Prior art keywords
- polydextrose
- phase
- uniform
- polymer
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det beskrives et fast, farmasøytisk preparat omfattende en fast dispersjon omfattende minst en aktiv bestanddel og en farmasøytisk akseptabel polymermatriks. Spesielt beskriver at den farmasøytisk akseptabel polymermatriks omfatter en blanding av (i) polydekstrose, i form av en kontinuerlig polydekstrosefase, for å favorisere desintegrering av preparater i et vandig medium, og (ii) minst en polymer forskjellig fra polydekstrose, i form av en kontinuerlig fase, hvorved polydekstrosen er i en konsentrasjon på minst 20 vekt-% og den minst ene polymer forskjellig fra polydekstrose er i en konsentrasjon på minst 20 vekt-%, beregnet på den totale vekt av den farmasøytisk akseptable, polymere matriks.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0409874A FR2875409B1 (fr) | 2004-09-17 | 2004-09-17 | Composition pharmaceutique comprenant une dispersion solide a matrice polymere comprenant une phase continue de polydextrose et une phase continue d'un polymere autre que du polydextrose |
| PCT/FR2005/002288 WO2006032762A2 (fr) | 2004-09-17 | 2005-09-15 | Composition pharmaceutique comprenant une dispersion solide a matrice polymere comprenant une phase continue de polydextrose et une phase continue d'un polymere autre que du polydextrose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071853L true NO20071853L (no) | 2007-06-15 |
Family
ID=34948358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071853A NO20071853L (no) | 2004-09-17 | 2007-04-11 | Farmasoytisk sammensetning inneholdende en fast dispersjon med en polymermatriks inneholdende en jevn polydekstrosefase og en jevn fase av en polymer forskjellig fra polydekstrose. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9084730B2 (no) |
| EP (1) | EP1791524B1 (no) |
| JP (1) | JP5224812B2 (no) |
| KR (1) | KR101342193B1 (no) |
| CN (2) | CN101039657B (no) |
| AU (1) | AU2005286396B2 (no) |
| BR (1) | BRPI0515390A (no) |
| CA (1) | CA2579673C (no) |
| EA (1) | EA012850B1 (no) |
| FR (1) | FR2875409B1 (no) |
| IL (1) | IL181773A0 (no) |
| MA (1) | MA28858B1 (no) |
| MX (1) | MX2007003162A (no) |
| NO (1) | NO20071853L (no) |
| NZ (1) | NZ553780A (no) |
| WO (1) | WO2006032762A2 (no) |
| ZA (1) | ZA200702214B (no) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2336117A1 (en) | 2005-05-26 | 2011-06-22 | Neuron Systems, Inc | Heterocyclic compounds for treating retinal diseases |
| AU2007212197B2 (en) * | 2006-02-09 | 2012-12-13 | Merck Sharp & Dohme Corp. | Polymer formulations of CETP inhibitors |
| WO2008135852A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Pharmaceutical compositions comprising nanoparticles and casein |
| FR2921835B1 (fr) * | 2007-10-05 | 2012-05-04 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Composition d'enrobage comprenant du polydextrose, procede pour sa preparation et utilisation pour enrober les formes solides ingerables |
| PE20091809A1 (es) | 2008-04-17 | 2009-12-03 | Sanofi Aventis | Uso de dronedarona para la preparacion de un medicamento para uso en la prevencion de la hospitalizacion cardiovascular o de la mortalidad |
| FR2930149B1 (fr) * | 2008-04-17 | 2011-02-18 | Sanofi Aventis | Association de dronedarone avec au moins un diuretique, son application en therapeutique |
| EP2116239A1 (en) * | 2008-04-29 | 2009-11-11 | Sanofi-Aventis | Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment |
| US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
| TWI540132B (zh) * | 2009-06-08 | 2016-07-01 | 亞培公司 | Bcl-2族群抑制劑之口服醫藥劑型 |
| TWI532484B (zh) * | 2009-06-08 | 2016-05-11 | 艾伯維有限公司 | 包含凋亡促進劑之固態分散劑 |
| CN102078307B (zh) * | 2009-12-01 | 2012-11-07 | 天津市汉康医药生物技术有限公司 | 一种盐酸决奈达隆固体分散体的药物组合物及其制备方法 |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
| WO2011135582A2 (en) | 2010-04-28 | 2011-11-03 | Cadila Healthcare Limited | Pharmaceutical compositions of dronedarone |
| WO2011135581A2 (en) | 2010-04-28 | 2011-11-03 | Cadila Healthcare Limited | Pharmaceutical compositions of dronedarone |
| JP2013526572A (ja) | 2010-05-17 | 2013-06-24 | アエリエ・ファーマシューティカルズ・インコーポレーテッド | 眼治療薬の送達のための薬物送達装置 |
| WO2012001673A1 (en) * | 2010-06-28 | 2012-01-05 | Mapi Pharma Holdings (Cyprus) Limited | Amorphous form of dronedarone |
| US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
| CN102342907A (zh) | 2010-07-30 | 2012-02-08 | 江苏恒瑞医药股份有限公司 | 决奈达隆固体分散体及其制备方法 |
| EP2605758A2 (en) | 2010-08-17 | 2013-06-26 | Lupin Limited | Controlled release formulations of dronedarone |
| UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| US9204667B2 (en) * | 2010-12-01 | 2015-12-08 | R.J. Reynolds Tobacco Company | Smokeless tobacco pastille and injection molding process for forming smokeless tobacco products |
| WO2013024411A1 (en) | 2011-08-12 | 2013-02-21 | Lupin Limited | Co-milled formulation of dronedarone |
| JP2015507003A (ja) | 2012-02-20 | 2015-03-05 | ルピン・リミテッドLupin Limited | ドロネダロンの二層錠剤 |
| CN103054820B (zh) * | 2012-08-22 | 2016-07-13 | 石药集团中奇制药技术(石家庄)有限公司 | 一种盐酸决奈达隆药物组合物及其制备方法 |
| CA2898631C (en) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
| NZ729172A (en) | 2013-01-31 | 2018-06-29 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
| JP2016529293A (ja) | 2013-08-27 | 2016-09-23 | ギリアド ファーマセット エルエルシー | 2つの抗ウイルス化合物の組合せ製剤 |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| CN108135907A (zh) | 2015-08-21 | 2018-06-08 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| KR20190050807A (ko) | 2016-09-09 | 2019-05-13 | 메르크 파텐트 게엠베하 | 고체 약학적 투여 형태의 제조 방법 |
| MX2020003425A (es) | 2017-10-10 | 2020-07-29 | Aldeyra Therapeutics Inc | Tratamiento de trastornos inflamatorios. |
| EP3833660A4 (en) | 2018-08-06 | 2022-05-11 | Aldeyra Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND THEIR USES |
| WO2020198064A1 (en) | 2019-03-26 | 2020-10-01 | Aldeyra Therapeutics, Inc. | Ophthalmic formulations and uses thereof |
| CA3137301A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| WO2021231792A1 (en) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
| KR102959023B1 (ko) | 2020-08-06 | 2026-04-29 | (주)코스모덱 | 고분자 네트워크 구조체에 의하여 안정화된 생리활성 복합체 및 이의 제조방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3612212A1 (de) * | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US5456932A (en) * | 1987-04-20 | 1995-10-10 | Fuisz Technologies Ltd. | Method of converting a feedstock to a shearform product and product thereof |
| CA2095776C (en) * | 1992-05-12 | 2007-07-10 | Richard C. Fuisz | Rapidly dispersable compositions containing polydextrose |
| FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5935600A (en) * | 1993-09-10 | 1999-08-10 | Fuisz Technologies Ltd. | Process for forming chewable quickly dispersing comestible unit and product therefrom |
| TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
| FR2761266B1 (fr) * | 1997-03-28 | 1999-07-02 | Sanofi Sa | Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates |
| DE19938672C2 (de) * | 1999-08-06 | 2001-11-22 | Biop Biopolymer Gmbh | Verfahren zur Herstellung einer thermoplastischen Polymermischung auf Stärkebasis durch reaktive Extrusion |
| JP2005500313A (ja) * | 2001-06-22 | 2005-01-06 | ファイザー・プロダクツ・インク | 基材中の低可溶性薬物の固体分散体および溶解度向上性ポリマーを含有する医薬品組成物 |
| US6566347B1 (en) * | 2001-08-22 | 2003-05-20 | Duquesne University Of The Holy Ghost | Controlled release pharmaceutical |
-
2004
- 2004-09-17 FR FR0409874A patent/FR2875409B1/fr not_active Expired - Lifetime
-
2005
- 2005-09-15 CN CN2005800354363A patent/CN101039657B/zh not_active Expired - Fee Related
- 2005-09-15 JP JP2007531798A patent/JP5224812B2/ja not_active Expired - Fee Related
- 2005-09-15 CA CA2579673A patent/CA2579673C/fr not_active Expired - Fee Related
- 2005-09-15 EP EP05802489.4A patent/EP1791524B1/fr not_active Expired - Lifetime
- 2005-09-15 BR BRPI0515390-5A patent/BRPI0515390A/pt not_active IP Right Cessation
- 2005-09-15 WO PCT/FR2005/002288 patent/WO2006032762A2/fr not_active Ceased
- 2005-09-15 AU AU2005286396A patent/AU2005286396B2/en not_active Ceased
- 2005-09-15 CN CN2011100789108A patent/CN102247601A/zh active Pending
- 2005-09-15 ZA ZA200702214A patent/ZA200702214B/xx unknown
- 2005-09-15 EA EA200700658A patent/EA012850B1/ru not_active IP Right Cessation
- 2005-09-15 NZ NZ553780A patent/NZ553780A/en not_active IP Right Cessation
- 2005-09-15 MX MX2007003162A patent/MX2007003162A/es active IP Right Grant
-
2007
- 2007-03-07 IL IL181773A patent/IL181773A0/en unknown
- 2007-03-14 MA MA29752A patent/MA28858B1/fr unknown
- 2007-03-15 US US11/686,611 patent/US9084730B2/en active Active
- 2007-04-11 NO NO20071853A patent/NO20071853L/no not_active Application Discontinuation
- 2007-04-16 KR KR1020077008644A patent/KR101342193B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102247601A (zh) | 2011-11-23 |
| NZ553780A (en) | 2010-08-27 |
| ZA200702214B (en) | 2008-09-25 |
| CA2579673A1 (fr) | 2006-03-30 |
| EP1791524B1 (fr) | 2014-11-19 |
| MA28858B1 (fr) | 2007-09-03 |
| EA012850B1 (ru) | 2009-12-30 |
| HK1111608A1 (en) | 2008-08-15 |
| JP5224812B2 (ja) | 2013-07-03 |
| FR2875409B1 (fr) | 2010-05-07 |
| MX2007003162A (es) | 2007-05-16 |
| KR20070055601A (ko) | 2007-05-30 |
| IL181773A0 (en) | 2007-07-04 |
| US20070243257A1 (en) | 2007-10-18 |
| EP1791524A2 (fr) | 2007-06-06 |
| FR2875409A1 (fr) | 2006-03-24 |
| JP2008513421A (ja) | 2008-05-01 |
| WO2006032762A2 (fr) | 2006-03-30 |
| KR101342193B1 (ko) | 2013-12-16 |
| CN101039657B (zh) | 2012-07-18 |
| US9084730B2 (en) | 2015-07-21 |
| AU2005286396B2 (en) | 2011-08-11 |
| BRPI0515390A (pt) | 2008-07-22 |
| WO2006032762A3 (fr) | 2006-06-01 |
| CN101039657A (zh) | 2007-09-19 |
| EA200700658A1 (ru) | 2007-08-31 |
| CA2579673C (fr) | 2014-11-18 |
| AU2005286396A1 (en) | 2006-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |