ATE383375T1 - Wti-modifiziertes peptid - Google Patents

Wti-modifiziertes peptid

Info

Publication number: ATE383375T1
Authority: AT; Austria
Prior art keywords: wti; modified peptide; active ingredient; peptide; dna
Prior art date: 2001-03-22

Application number

AT02708646T

Other languages

English (en)

Inventor

Haruo Sugiyama

Original Assignee

Int Inst Cancer Immunology Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-22

Filing date

2002-03-22

Publication date

2008-01-15

2002-03-22 Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE383375T1 publication Critical patent/ATE383375T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
239000004480 active ingredient Substances 0.000 abstract 2
VXDXZGYXHIADHF-YJRXYDGGSA-N Cys-Tyr-Thr Chemical compound [H]N[C@@H](CS)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O VXDXZGYXHIADHF-YJRXYDGGSA-N 0.000 abstract 1
108010041986 DNA Vaccines Proteins 0.000 abstract 1
229940021995 DNA vaccine Drugs 0.000 abstract 1
YNOVBMBQSQTLFM-DCAQKATOSA-N Met-Asn-Leu Chemical compound [H]N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O YNOVBMBQSQTLFM-DCAQKATOSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
NAQBQJOGGYGCOT-QEJZJMRPSA-N Trp-Asn-Gln Chemical compound [H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O NAQBQJOGGYGCOT-QEJZJMRPSA-N 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
229940022399 cancer vaccine Drugs 0.000 abstract 1
238000009566 cancer vaccine Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Zoology (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)

AT02708646T 2001-03-22 2002-03-22 Wti-modifiziertes peptid ATE383375T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2001083250		2001-03-22

Publications (1)

Publication Number	Publication Date
ATE383375T1 true ATE383375T1 (de)	2008-01-15

Family

ID=18939092

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02708646T ATE383375T1 (de)	2001-03-22	2002-03-22	Wti-modifiziertes peptid

Country Status (12)

Country	Link
US (2)	US20040097703A1 (de)
EP (1)	EP1371664B1 (de)
JP (2)	JP3728439B2 (de)
KR (1)	KR100863853B1 (de)
CN (1)	CN1281625C (de)
AT (1)	ATE383375T1 (de)
BR (1)	BRPI0208183B8 (de)
CA (1)	CA2440303C (de)
DE (1)	DE60224508T2 (de)
ES (1)	ES2298353T3 (de)
TW (1)	TWI318630B (de)
WO (1)	WO2002079253A1 (de)

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EP1103564B1 (de)	1998-07-31	2009-01-07	International Institute of Cancer Immunology, Inc.	Krebsantigene, basierend auf dem tumorunterdrückenden genprodukt wt1
BRPI0208183B8 (pt)	2001-03-22	2021-05-25	Sugiyama Haruo	peptídeo antígeno de câncer modificado por wt1 e vacinas para câncer
WO2003028757A1 (en) *	2001-09-28	2003-04-10	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
WO2003028758A1 (en) *	2001-09-28	2003-04-10	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
JP2003243616A (ja)	2002-02-20	2003-08-29	Seiko Epson Corp	半導体装置の製造方法
KR101050703B1 (ko) *	2002-06-12	2011-07-20	추가이 세이야쿠 가부시키가이샤	Ｈｌａ-ａ24-구속성 암 항원 펩티드
ES2538486T3 (es)	2002-09-12	2015-06-22	International Institute Of Cancer Immunology, Inc.	Preparación de péptidos antigénicos contra el cáncer
WO2004026897A1 (ja) *	2002-09-20	2004-04-01	Chugai Seiyaku Kabushiki Kaisha	Ｗｔ１置換型ペプチド
US20060217297A1 (en) *	2003-01-15	2006-09-28	Haruo Sugiyama	Dimerized peptide
ES2443582T3 (es)	2003-06-27	2014-02-19	International Institute Of Cancer Immunology, Inc.	Método para diagnosticar el cáncer que comprende la medición de las células precursoras de CTL específicos de WT1
CN101580538B (zh)	2003-11-05	2013-06-19	株式会社国际癌症免疫研究所	Wt1衍生的hla-dr-结合抗原肽
ES2556232T3 (es) *	2004-03-31	2016-01-14	International Institute Of Cancer Immunology, Inc.	Péptidos antigénicos del cáncer derivados de WT1
WO2007047764A2 (en)	2005-10-17	2007-04-26	Sloan Kettering Institute For Cancer Research	Wt1 hla class ii-binding peptides and compositions and methods comprising same
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NZ601175A (en) *	2006-12-28	2012-12-21	Int Inst Cancer Immunology Inc	Hla-a*1101-restricted wt1 peptide and pharmaceutical composition comprising the same
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CA2940962C (en)	2007-12-05	2018-07-24	International Institute Of Cancer Immunology, Inc.	Cancer vaccine composition
EP2626418B8 (de)	2010-10-05	2021-03-24	International Institute of Cancer Immunology, Inc.	Verfahren zur aktivierung von t-helferzellen
CN103764826A (zh)	2011-06-28	2014-04-30	株式会社癌免疫研究所	肽癌抗原-特异性t细胞的受体基因
US9539299B2 (en) *	2011-10-27	2017-01-10	International Institute Of Cancer Immunology, Inc.	Combination therapy with WT1 peptide vaccine and temozolomide
HK1204261A1 (en)	2012-01-13	2015-11-13	Memorial Sloan Kettering Cancer Center	Immunogenic wt-1 peptides and methods of use thereof
WO2014007266A1 (ja)	2012-07-02	2014-01-09	大日本住友製薬株式会社	癌抗原ペプチド経皮剤
CN104797711B (zh) *	2012-09-12	2018-09-21	株式会社癌免疫研究所	抗原特异性辅助性t细胞受体基因
CA2892660C (en)	2012-12-17	2022-02-15	Otsuka Pharmaceutical Co., Ltd.	Method for activating helper t cell
US10815273B2 (en)	2013-01-15	2020-10-27	Memorial Sloan Kettering Cancer Center	Immunogenic WT-1 peptides and methods of use thereof
PT2945647T (pt) *	2013-01-15	2020-11-26	Memorial Sloan Kettering Cancer Center	Péptidos imunogénicos wt-1 e métodos de uso dos mesmos
JP6250288B2 (ja) *	2013-01-30	2017-12-20	株式会社医学生物学研究所	Ｔ細胞レセプターおよびその利用
RU2685933C2 (ru)	2013-02-05	2019-04-23	Нитто Денко Корпорейшн	Композиция противораковой вакцины, содержащая пептид wt1, для трансдермального введения
CN103961307B (zh)	2013-02-05	2019-11-29	日东电工株式会社	经皮给予用wt1肽癌症疫苗组合物
EP2762156A1 (de)	2013-02-05	2014-08-06	Nitto Denko Corporation	Bandpräparat mit WT1-Peptidkrebsimpfstoff zur transdermalen Verabreichung
CN103961702B (zh)	2013-02-05	2019-04-09	日东电工株式会社	粘膜给予用wt1肽癌症疫苗组合物
ES2694328T3 (es)	2013-03-12	2018-12-19	Sumitomo Dainippon Pharma Co., Ltd.	Composición acuosa líquida
DK2982681T3 (en)	2013-03-29	2018-12-10	Sumitomo Dainippon Pharma Co Ltd	WT1 ANTIGENPEPTIDKONJUGATVACCINE
WO2014157704A1 (ja)	2013-03-29	2014-10-02	大日本住友製薬株式会社	Ｅｒａｐ１によるトリミング機能をきっかけとしたコンジュゲートワクチン
WO2014185387A1 (ja)	2013-05-13	2014-11-20	株式会社癌免疫研究所	免疫療法の臨床効果の予測法
KR101804343B1 (ko) *	2014-02-26	2017-12-04	텔라 가부시키가이샤	Ｗｔ１ 항원성 폴리펩티드 및 상기 폴리펩티드를 포함하는 항종양제
EP3199175B1 (de)	2014-09-27	2022-03-23	Sumitomo Dainippon Pharma Co., Ltd.	Pharmazeutische zusammensetzung zur injektion
WO2018101309A1 (ja)	2016-11-30	2018-06-07	大日本住友製薬株式会社	Ｗｔ１ヘルパーペプチド及びこれと癌抗原ペプチドコンジュゲート体との組合せ
JPWO2018181648A1 (ja)	2017-03-30	2020-02-13	大日本住友製薬株式会社	Ｗｔ１癌抗原ペプチドおよびこれを含むペプチドコンジュゲート体
EP3858377A4 (de)	2018-09-28	2022-11-30	Sumitomo Pharma Co., Ltd.	Injizierbare zusammensetzung
JP7393752B2 (ja)	2018-10-05	2023-12-07	株式会社癌免疫研究所	良性腫瘍の予防または治療薬
TWI875736B (zh)	2019-02-28	2025-03-11	日商住友製藥股份有限公司	選擇可期待用於治療或預防癌之醫藥組合物之效果之對象之方法
WO2021230247A1 (ja)	2020-05-12	2021-11-18	大日本住友製薬株式会社	癌を処置するための医薬組成物
CN111647066B (zh) *	2020-07-01	2020-12-18	维肽瀛(上海)生物技术有限公司	Wt1多肽肿瘤抑制剂
JPWO2023017836A1 (de)	2021-08-12	2023-02-16

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BRPI0208183B8 (pt)	2001-03-22	2021-05-25	Sugiyama Haruo	peptídeo antígeno de câncer modificado por wt1 e vacinas para câncer
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WO2003028757A1 (en) *	2001-09-28	2003-04-10	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
WO2003028758A1 (en) *	2001-09-28	2003-04-10	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
KR101050703B1 (ko)	2002-06-12	2011-07-20	추가이 세이야쿠 가부시키가이샤	Ｈｌａ-ａ24-구속성 암 항원 펩티드
ES2538486T3 (es)	2002-09-12	2015-06-22	International Institute Of Cancer Immunology, Inc.	Preparación de péptidos antigénicos contra el cáncer
WO2004026897A1 (ja)	2002-09-20	2004-04-01	Chugai Seiyaku Kabushiki Kaisha	Ｗｔ１置換型ペプチド
US20060217297A1 (en)	2003-01-15	2006-09-28	Haruo Sugiyama	Dimerized peptide
ES2443582T3 (es)	2003-06-27	2014-02-19	International Institute Of Cancer Immunology, Inc.	Método para diagnosticar el cáncer que comprende la medición de las células precursoras de CTL específicos de WT1
CN101580538B (zh)	2003-11-05	2013-06-19	株式会社国际癌症免疫研究所	Wt1衍生的hla-dr-结合抗原肽
ES2556232T3 (es)	2004-03-31	2016-01-14	International Institute Of Cancer Immunology, Inc.	Péptidos antigénicos del cáncer derivados de WT1

2002
- 2002-03-22 BR BRPI0208183 patent/BRPI0208183B8/pt not_active IP Right Cessation
- 2002-03-22 TW TW091105633A patent/TWI318630B/zh not_active IP Right Cessation
- 2002-03-22 CA CA2440303A patent/CA2440303C/en not_active Expired - Lifetime
- 2002-03-22 US US10/471,835 patent/US20040097703A1/en not_active Abandoned
- 2002-03-22 KR KR1020037011790A patent/KR100863853B1/ko not_active Expired - Lifetime
- 2002-03-22 JP JP2002577877A patent/JP3728439B2/ja not_active Expired - Lifetime
- 2002-03-22 EP EP02708646A patent/EP1371664B1/de not_active Expired - Lifetime
- 2002-03-22 ES ES02708646T patent/ES2298353T3/es not_active Expired - Lifetime
- 2002-03-22 AT AT02708646T patent/ATE383375T1/de not_active IP Right Cessation
- 2002-03-22 DE DE60224508T patent/DE60224508T2/de not_active Expired - Lifetime
- 2002-03-22 CN CNB028070259A patent/CN1281625C/zh not_active Expired - Lifetime
- 2002-03-22 WO PCT/JP2002/002794 patent/WO2002079253A1/ja not_active Ceased
2005
- 2005-08-08 JP JP2005229180A patent/JP3819930B2/ja not_active Expired - Lifetime
2009
- 2009-09-02 US US12/552,660 patent/US8105604B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1371664B1 (de)	2008-01-09
US20040097703A1 (en)	2004-05-20
DE60224508T2 (de)	2008-12-24
DE60224508D1 (de)	2008-02-21
BR0208183A (pt)	2004-03-02
JPWO2002079253A1 (ja)	2004-07-22
KR20030084970A (ko)	2003-11-01
HK1070078A1 (en)	2005-06-10
US20090325886A1 (en)	2009-12-31
CN1281625C (zh)	2006-10-25
BRPI0208183B1 (pt)	2018-08-28
TWI318630B (en)	2009-12-21
KR100863853B1 (ko)	2008-10-15
CN1531553A (zh)	2004-09-22
JP2006034296A (ja)	2006-02-09
JP3728439B2 (ja)	2005-12-21
US8105604B2 (en)	2012-01-31
ES2298353T3 (es)	2008-05-16
JP3819930B2 (ja)	2006-09-13
CA2440303A1 (en)	2002-10-10
EP1371664A1 (de)	2003-12-17
EP1371664A4 (de)	2006-03-22
WO2002079253A1 (en)	2002-10-10
CA2440303C (en)	2013-03-19
BRPI0208183B8 (pt)	2021-05-25

Legal Events

Date	Code	Title	Description
2008-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE383375T1 (de)	2008-01-15	Wti-modifiziertes peptid
AU2002302255A1 (en)	2002-12-09	Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
NO20073914L (no)	2004-03-10	Biologisk aktive peptider
WO2002059143A3 (en)	2004-01-22	Therapeutic peptides for demyelinating conditions
IS2670B (is)	2010-09-15	Bóluefni og notkun þar á til meðhöndlunar á blandaðri hreyfitaugahrörnun
MXPA03010684A (es)	2005-11-04	Peptidos y el uso de los mismos para oscurecer la piel.
BR0214363A (pt)	2004-10-26	Anticorpo, uso de um anticorpo, medicamento, método de fabricação de um medicamento e pacote farmacêutico para o tratamento de infecção
NO20025064L (no)	2002-12-20	RGO koblet til peptider
DE50206480D1 (de)	2006-05-24	Antimikrobiell wirkendes peptid
ATE469655T1 (de)	2010-06-15	Bakteriophagenvermittelte impfung
WO2002058725A3 (fr)	2003-01-09	Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
DE602004028266D1 (de)	2010-09-02	Angiogene peptide und ihre verwendungen
CY1109946T1 (el)	2014-09-10	Τροποποιημενα πεπτιδια και η χρηση τους για τη θεραπεια αυτοανοσων νοσων
DK1268522T3 (da)	2009-01-12	LH-RH-antagonister samt fremstilling deraf og anvendelse deraf som lægemidler
EP1557466A4 (de)	2006-02-08	Tumorantigenprotein und dessen verwendung
NZ513549A (en)	2003-03-28	Malaria vaccine
EA200400392A1 (ru)	2004-10-28	Связывающий каспазу-8 белок, его получение и применение
WO2003093300A3 (en)	2004-09-10	Anti-microbial peptides and compositions
ES2176363T3 (es)	2002-12-01	Peptidos de la proteina gag del vih, su preparacion y su uso.
WO2001090139A3 (en)	2002-06-20	A ligand for enhancing oral and cns delivery of biological agents
FR2819256B1 (fr)	2004-04-30	Polypeptide induisant des anticorps neutralisant le vih
IT1307333B1 (it)	2001-10-30	Peptidi derivati dall'allergene parj2 del polline di parietariajudaica.
BR0107799A (pt)	2002-10-22	Proteìna de interação de wt1 wtip
WO2003030843A3 (de)	2003-08-21	Haarbehandlungsmittel