ATE383375T1 - Wti-modifiziertes peptid - Google Patents

Wti-modifiziertes peptid

Info

Publication number: ATE383375T1
Authority: AT; Austria
Prior art keywords: wti; modified peptide; active ingredient; peptide; dna
Prior art date: 2001-03-22

Application number

AT02708646T

Other languages

English (en)

Inventor

Haruo Sugiyama

Original Assignee

Int Inst Cancer Immunology Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-22

Filing date

2002-03-22

Publication date

2008-01-15

2002-03-22 Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE383375T1 publication Critical patent/ATE383375T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
239000004480 active ingredient Substances 0.000 abstract 2
VXDXZGYXHIADHF-YJRXYDGGSA-N Cys-Tyr-Thr Chemical compound [H]N[C@@H](CS)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O VXDXZGYXHIADHF-YJRXYDGGSA-N 0.000 abstract 1
108010041986 DNA Vaccines Proteins 0.000 abstract 1
229940021995 DNA vaccine Drugs 0.000 abstract 1
YNOVBMBQSQTLFM-DCAQKATOSA-N Met-Asn-Leu Chemical compound [H]N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O YNOVBMBQSQTLFM-DCAQKATOSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
NAQBQJOGGYGCOT-QEJZJMRPSA-N Trp-Asn-Gln Chemical compound [H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O NAQBQJOGGYGCOT-QEJZJMRPSA-N 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
229940022399 cancer vaccine Drugs 0.000 abstract 1
238000009566 cancer vaccine Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Zoology (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Hematology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)

AT02708646T 2001-03-22 2002-03-22 Wti-modifiziertes peptid ATE383375T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2001083250		2001-03-22

Publications (1)

Publication Number	Publication Date
ATE383375T1 true ATE383375T1 (de)	2008-01-15

Family

ID=18939092

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02708646T ATE383375T1 (de)	2001-03-22	2002-03-22	Wti-modifiziertes peptid

Country Status (12)

Country	Link
US (2)	US20040097703A1 (de)
EP (1)	EP1371664B1 (de)
JP (2)	JP3728439B2 (de)
KR (1)	KR100863853B1 (de)
CN (1)	CN1281625C (de)
AT (1)	ATE383375T1 (de)
BR (1)	BRPI0208183B8 (de)
CA (1)	CA2440303C (de)
DE (1)	DE60224508T2 (de)
ES (1)	ES2298353T3 (de)
TW (1)	TWI318630B (de)
WO (1)	WO2002079253A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4932199A (en)	1998-07-31	2000-02-21	Haruo Sugiyama	Cancer antigens based on tumor suppressor gene wt1 product
EP1371664B1 (de) *	2001-03-22	2008-01-09	International Institute of Cancer Immunology, Inc.	Wti-modifiziertes peptid
US20050002951A1 (en) *	2001-09-28	2005-01-06	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
JP5230891B2 (ja) *	2001-09-28	2013-07-10	株式会社癌免疫研究所	抗原特異的ｔ細胞の新規な誘導方法
JP2003243616A (ja)	2002-02-20	2003-08-29	Seiko Epson Corp	半導体装置の製造方法
WO2003106682A1 (ja)	2002-06-12	2003-12-24	中外製薬株式会社	Ｈｌａ−ａ２４拘束性癌抗原ペプチド
WO2004024175A1 (ja) *	2002-09-12	2004-03-25	Haruo Sugiyama	癌抗原ペプチド製剤
ES2331305T3 (es) *	2002-09-20	2009-12-29	International Institute Of Cancer Immunology, Inc.	Peptidos de wt1 de tipo sustituido.
ES2332590T3 (es) *	2003-01-15	2010-02-09	International Institute Of Cancer Immunology, Inc.	Dimero peptidico.
WO2005001117A1 (ja)	2003-06-27	2005-01-06	Haruo Sugiyama	Ｗｔ１ワクチン適応患者の選択方法
KR101213015B1 (ko)	2003-11-05	2012-12-26	인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드	Ｗｔ１ 로부터 유도된 ｈｌａ-ｄｒ 결합성 항원 펩티드
PT1731605E (pt) *	2004-03-31	2010-04-14	Int Inst Cancer Immunology Inc	Péptidos antigénicos de cancro derivados de wt1
EP1951281B1 (de)	2005-10-17	2015-04-15	Sloan Kettering Institute For Cancer Research	Wt1 hla klasse ii-bindungspeptide und diese umfassende zusammensetzungen und verfahren
CA2631292C (en)	2005-11-30	2014-05-06	International Institute Of Cancer Immunology, Inc.	Derivatised wt1 cancer antigen peptides and their use
AU2007218649B2 (en) *	2006-02-22	2013-01-10	International Institute Of Cancer Immunology, Inc.	HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
WO2007120673A2 (en)	2006-04-10	2007-10-25	Sloan Kettering Institute For Cancer Research	Immunogenic wt-1 peptides and methods of use thereof
EP2341142B8 (de) *	2006-12-28	2015-01-14	International Institute of Cancer Immunology, Inc.	HLA-A*1101-beschränktes WT1-Peptid und pharmazeutische Zusammensetzung damit
BRPI0808084A2 (pt)	2007-02-27	2014-07-22	Int Inst Cancer Immunology Inc	Método para ativação de células t auxiliadoras e composição para uso no método.
KR101773690B1 (ko)	2007-03-05	2017-08-31	인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드	암 항원 특이적 ｔ 세포의 수용체 유전자 및 그것에 따라 코드되는 펩티드 및 이들의 사용
CA2940962C (en)	2007-12-05	2018-07-24	International Institute Of Cancer Immunology, Inc.	Cancer vaccine composition
KR20140009168A (ko)	2010-10-05	2014-01-22	인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드	헬퍼 ｔ 세포의 활성화 방법
CA2839663A1 (en)	2011-06-28	2013-01-03	International Institute Of Cancer Immunology, Inc.	Receptor gene for peptide cancer antigen-specific t cell
US9539299B2 (en) *	2011-10-27	2017-01-10	International Institute Of Cancer Immunology, Inc.	Combination therapy with WT1 peptide vaccine and temozolomide
AU2013207669C1 (en)	2012-01-13	2018-05-31	Memorial Sloan Kettering Cancer Center	Immunogenic WT-1 peptides and methods of use thereof
JP6163486B2 (ja)	2012-07-02	2017-07-12	大日本住友製薬株式会社	癌抗原ペプチド経皮剤
CA2884366A1 (en)	2012-09-12	2014-03-20	International Institute Of Cancer Immunology, Inc.	Antigen-specific helper t-cell receptor genes
SG10201705028WA (en)	2012-12-17	2017-07-28	Otsuka Pharma Co Ltd	Method for activating helper t cell
RS61173B1 (sr) *	2013-01-15	2021-01-29	Memorial Sloan Kettering Cancer Center	Imunogeni wt-1 peptidi i postupci za njihovu upotrebu
US10815273B2 (en)	2013-01-15	2020-10-27	Memorial Sloan Kettering Cancer Center	Immunogenic WT-1 peptides and methods of use thereof
JP6250288B2 (ja) *	2013-01-30	2017-12-20	株式会社医学生物学研究所	Ｔ細胞レセプターおよびその利用
EP2762152A1 (de)	2013-02-05	2014-08-06	Nitto Denko Corporation	WT1-Peptidkrebsimpfstoffzusammensetzung zur transdermalen Verabreichung
RU2687026C2 (ru)	2013-02-05	2019-05-06	Нитто Денко Корпорейшн	Вакцинная композиция против злокачественной опухоли на основе пептида wt1 для мукозального введения
KR102050931B1 (ko)	2013-02-05	2019-12-02	닛토덴코 가부시키가이샤	경피 투여용 ｗｔ1 펩티드 암 백신 테이프제
KR20140100419A (ko)	2013-02-05	2014-08-14	닛토덴코 가부시키가이샤	경피 투여용 ｗｔ1 펩티드 암 백신 조성물
EP2974734B1 (de)	2013-03-12	2018-10-10	Sumitomo Dainippon Pharma Co., Ltd.	Flüssige, wässrige zusammensetzung
WO2014157704A1 (ja)	2013-03-29	2014-10-02	大日本住友製薬株式会社	Ｅｒａｐ１によるトリミング機能をきっかけとしたコンジュゲートワクチン
SG11201507883SA (en)	2013-03-29	2015-10-29	Sumitomo Dainippon Pharma Co Ltd	Wt1-antigen peptide conjugate vaccine
KR20160007579A (ko)	2013-05-13	2016-01-20	인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드	면역요법의 임상 효과의 예측법
JP6005305B2 (ja) *	2014-02-26	2016-10-12	テラ株式会社	Ｗｔ１抗原性ポリペプチド、及び該ポリペプチドを含む抗腫瘍剤
ES2916834T3 (es)	2014-09-27	2022-07-06	Sumitomo Pharma Co Ltd	Composición farmacéutica para inyección
US12383608B2 (en)	2016-11-30	2025-08-12	Sumitomo Pharma Co., Ltd.	WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides
JPWO2018181648A1 (ja)	2017-03-30	2020-02-13	大日本住友製薬株式会社	Ｗｔ１癌抗原ペプチドおよびこれを含むペプチドコンジュゲート体
JP7162675B2 (ja)	2018-09-28	2022-10-28	住友ファーマ株式会社	注射用組成物
CA3115240A1 (en)	2018-10-05	2020-04-09	International Institute Of Cancer Immunology, Inc.	Composition for preventing or treating benign tumor
TWI875736B (zh)	2019-02-28	2025-03-11	日商住友製藥股份有限公司	選擇可期待用於治療或預防癌之醫藥組合物之效果之對象之方法
JP7153287B2 (ja)	2020-05-12	2022-10-14	住友ファーマ株式会社	癌を処置するための医薬組成物
CN111647066B (zh) *	2020-07-01	2020-12-18	维肽瀛(上海)生物技术有限公司	Wt1多肽肿瘤抑制剂
MX2024001843A (es)	2021-08-12	2024-05-16	Int Inst Cancer Immunology Inc	Composición farmacéutica y método para tratar o prevenir cáncer.

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6122018A (ja)	1984-07-06	1986-01-30	Green Cross Corp:The	癌免疫療法増強剤
JP3393867B2 (ja)	1989-11-13	2003-04-07	マサチユーセツツ・インステイテユート・オブ・テクノロジー	ウィルムス腫瘍遺伝子の位置決定と特徴付け
EP0741580A4 (de)	1993-12-14	2001-07-11	Univ Johns Hopkins Med	Die kontrollierte freisetzung von pharmazeutisch aktiven substanzen in der immuntherapie
US5622835A (en)	1994-04-28	1997-04-22	The Wistar Institute Of Anatomy & Biology	WT1 monoclonal antibodies
EP1167379A3 (de)	1994-07-15	2004-09-08	University Of Iowa Research Foundation	Immunomodulatorische Oligonukleotide
US6034235A (en) *	1995-06-01	2000-03-07	Tadamitsu Kishimoto	Growth inhibitor for leukemia cell comprising antisense oligonucleotide derivative to wilms tumor gene (WT1)
JP3904260B2 (ja)	1995-06-01	2007-04-11	岸本忠三	ウイルムス腫瘍遺伝子（ｗｔ１）に対するアンチセンスオリゴヌクレオチド誘導体を含んで成る白血病細胞増殖阻害剤
DE59611362D1 (de) *	1995-09-19	2006-08-17	Bayer Bioscience Gmbh	Pflanzen, die eine modifizierte stärke synthetisieren, verfahren zu ihrer herstellung sowie modifizierte stärke
US20030092656A1 (en) *	1997-07-16	2003-05-15	Haruo Sugiyama	Therapeutic agents for treatment of solid tumors comprising an expression-inhibiting sustance against Wilms' tumor gene (WT1)
JP4789095B2 (ja)	1997-07-16	2011-10-05	治夫杉山	ウイルムス腫瘍遺伝子（ｗｔ１）に対する発現阻害物質を含んで成る固形腫瘍治療剤
US5985264A (en)	1998-03-05	1999-11-16	The Medical College Of Ohio	IL-12 Stimulation of Neonatal immunity
AU4932199A (en)	1998-07-31	2000-02-21	Haruo Sugiyama	Cancer antigens based on tumor suppressor gene wt1 product
US20030235557A1 (en) *	1998-09-30	2003-12-25	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
US20030072767A1 (en) *	1998-09-30	2003-04-17	Alexander Gaiger	Compositions and methods for WT1 specific immunotherapy
AR021849A1 (es) *	1998-09-30	2002-08-07	Corixa Corp	Composiciones y metodos para la inmunoterapia especifica de wt1
US7144581B2 (en) *	2000-10-09	2006-12-05	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
US7901693B2 (en) *	1998-09-30	2011-03-08	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
US7655249B2 (en) *	1998-09-30	2010-02-02	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
US20030215458A1 (en) *	1998-09-30	2003-11-20	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
US20030039635A1 (en) *	1998-09-30	2003-02-27	Corixa Corporation	Compositions and methods for WT1 specific immunotherapy
GB9823897D0 (en)	1998-11-02	1998-12-30	Imp College Innovations Ltd	Immunotherapeutic methods and molecules
CA2359110A1 (en)	1999-01-12	2000-07-20	Ronald James Boon	Combination of hepatitis b vaccine with antiviral agents
PT1031346E (pt)	1999-01-27	2002-09-30	Idea Ag	Vacinacao nao invasiva atraves da pele
JP2001089389A (ja)	1999-07-22	2001-04-03	Sumitomo Pharmaceut Co Ltd	抗原特異的ｔ細胞の誘導剤
EP1681064A1 (de)	1999-07-22	2006-07-19	Dainippon Sumitomo Pharma Co., Ltd.	Induktion von antigen-spezifischen T-Zellen durch Interferon
CA2401070A1 (en)	2000-02-22	2001-08-30	Corixa Corporation	Compositions and methods for diagnosis and therapy of malignant mesothelioma
EP1371664B1 (de)	2001-03-22	2008-01-09	International Institute of Cancer Immunology, Inc.	Wti-modifiziertes peptid
US7553494B2 (en) *	2001-08-24	2009-06-30	Corixa Corporation	WT1 fusion proteins
JP5230891B2 (ja) *	2001-09-28	2013-07-10	株式会社癌免疫研究所	抗原特異的ｔ細胞の新規な誘導方法
US20050002951A1 (en) *	2001-09-28	2005-01-06	Haruo Sugiyama	Novel method of inducing antigen-specific t cells
WO2003106682A1 (ja)	2002-06-12	2003-12-24	中外製薬株式会社	Ｈｌａ−ａ２４拘束性癌抗原ペプチド
WO2004024175A1 (ja) *	2002-09-12	2004-03-25	Haruo Sugiyama	癌抗原ペプチド製剤
ES2331305T3 (es) *	2002-09-20	2009-12-29	International Institute Of Cancer Immunology, Inc.	Peptidos de wt1 de tipo sustituido.
ES2332590T3 (es) *	2003-01-15	2010-02-09	International Institute Of Cancer Immunology, Inc.	Dimero peptidico.
WO2005001117A1 (ja)	2003-06-27	2005-01-06	Haruo Sugiyama	Ｗｔ１ワクチン適応患者の選択方法
KR101213015B1 (ko)	2003-11-05	2012-12-26	인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드	Ｗｔ１ 로부터 유도된 ｈｌａ-ｄｒ 결합성 항원 펩티드
PT1731605E (pt)	2004-03-31	2010-04-14	Int Inst Cancer Immunology Inc	Péptidos antigénicos de cancro derivados de wt1

2002
- 2002-03-22 EP EP02708646A patent/EP1371664B1/de not_active Expired - Lifetime
- 2002-03-22 TW TW091105633A patent/TWI318630B/zh not_active IP Right Cessation
- 2002-03-22 KR KR1020037011790A patent/KR100863853B1/ko not_active Expired - Lifetime
- 2002-03-22 AT AT02708646T patent/ATE383375T1/de not_active IP Right Cessation
- 2002-03-22 WO PCT/JP2002/002794 patent/WO2002079253A1/ja not_active Ceased
- 2002-03-22 ES ES02708646T patent/ES2298353T3/es not_active Expired - Lifetime
- 2002-03-22 DE DE60224508T patent/DE60224508T2/de not_active Expired - Lifetime
- 2002-03-22 CA CA2440303A patent/CA2440303C/en not_active Expired - Lifetime
- 2002-03-22 CN CNB028070259A patent/CN1281625C/zh not_active Expired - Lifetime
- 2002-03-22 US US10/471,835 patent/US20040097703A1/en not_active Abandoned
- 2002-03-22 JP JP2002577877A patent/JP3728439B2/ja not_active Expired - Lifetime
- 2002-03-22 BR BR0208183-0 patent/BRPI0208183B8/pt not_active IP Right Cessation
2005
- 2005-08-08 JP JP2005229180A patent/JP3819930B2/ja not_active Expired - Lifetime
2009
- 2009-09-02 US US12/552,660 patent/US8105604B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BRPI0208183B1 (pt)	2018-08-28
WO2002079253A1 (en)	2002-10-10
JP3819930B2 (ja)	2006-09-13
CN1281625C (zh)	2006-10-25
CA2440303A1 (en)	2002-10-10
KR20030084970A (ko)	2003-11-01
CN1531553A (zh)	2004-09-22
TWI318630B (en)	2009-12-21
KR100863853B1 (ko)	2008-10-15
HK1070078A1 (en)	2005-06-10
BRPI0208183B8 (pt)	2021-05-25
US20090325886A1 (en)	2009-12-31
EP1371664A4 (de)	2006-03-22
JP2006034296A (ja)	2006-02-09
CA2440303C (en)	2013-03-19
US20040097703A1 (en)	2004-05-20
JPWO2002079253A1 (ja)	2004-07-22
DE60224508D1 (de)	2008-02-21
ES2298353T3 (es)	2008-05-16
EP1371664A1 (de)	2003-12-17
US8105604B2 (en)	2012-01-31
BR0208183A (pt)	2004-03-02
EP1371664B1 (de)	2008-01-09
DE60224508T2 (de)	2008-12-24
JP3728439B2 (ja)	2005-12-21

Legal Events

Date	Code	Title	Description
2008-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60224508D1 (de)	2008-02-21	Wti-modifiziertes peptid
MXPA04000597A (es)	2004-04-20	Peptidos novedosos de la proteina g del virus sincicial respiratorio (rsv), y su uso en una vacuna.
NO20073914L (no)	2004-03-10	Biologisk aktive peptider
WO2002059143A3 (en)	2004-01-22	Therapeutic peptides for demyelinating conditions
IS2670B (is)	2010-09-15	Bóluefni og notkun þar á til meðhöndlunar á blandaðri hreyfitaugahrörnun
MXPA03010684A (es)	2005-11-04	Peptidos y el uso de los mismos para oscurecer la piel.
BR0214363A (pt)	2004-10-26	Anticorpo, uso de um anticorpo, medicamento, método de fabricação de um medicamento e pacote farmacêutico para o tratamento de infecção
NO20025064L (no)	2002-12-20	RGO koblet til peptider
DE50206480D1 (de)	2006-05-24	Antimikrobiell wirkendes peptid
ATE469655T1 (de)	2010-06-15	Bakteriophagenvermittelte impfung
WO2002058725A3 (fr)	2003-01-09	Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
DE602004028266D1 (de)	2010-09-02	Angiogene peptide und ihre verwendungen
DK1268522T3 (da)	2009-01-12	LH-RH-antagonister samt fremstilling deraf og anvendelse deraf som lægemidler
ATE441713T1 (de)	2009-09-15	Tumorantigenprotein und dessen verwendung
NZ513549A (en)	2003-03-28	Malaria vaccine
EA200400392A1 (ru)	2004-10-28	Связывающий каспазу-8 белок, его получение и применение
WO2003093300A3 (en)	2004-09-10	Anti-microbial peptides and compositions
ES2176363T3 (es)	2002-12-01	Peptidos de la proteina gag del vih, su preparacion y su uso.
WO2001090139A3 (en)	2002-06-20	A ligand for enhancing oral and cns delivery of biological agents
FR2819256B1 (fr)	2004-04-30	Polypeptide induisant des anticorps neutralisant le vih
IT1307333B1 (it)	2001-10-30	Peptidi derivati dall'allergene parj2 del polline di parietariajudaica.
BR0107799A (pt)	2002-10-22	Proteìna de interação de wt1 wtip
WO2003030843A3 (de)	2003-08-21	Haarbehandlungsmittel