ATE384001T1 - Verfahren zur herstellung von dosierinhalatorformulierungen - Google Patents

Verfahren zur herstellung von dosierinhalatorformulierungen

Info

Publication number
ATE384001T1
ATE384001T1 AT03791745T AT03791745T ATE384001T1 AT E384001 T1 ATE384001 T1 AT E384001T1 AT 03791745 T AT03791745 T AT 03791745T AT 03791745 T AT03791745 T AT 03791745T AT E384001 T1 ATE384001 T1 AT E384001T1
Authority
AT
Austria
Prior art keywords
metered dose
dose inhaler
container
suspension
solution
Prior art date
Application number
AT03791745T
Other languages
English (en)
Inventor
Saeed Chaudhry
Stefan Sharpe
Julianne Berry
Joel Sequeira
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE384001T1 publication Critical patent/ATE384001T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/003—Adding propellants in fluid form to aerosol containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT03791745T 2002-08-27 2003-08-26 Verfahren zur herstellung von dosierinhalatorformulierungen ATE384001T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40612702P 2002-08-27 2002-08-27
US42243602P 2002-10-30 2002-10-30

Publications (1)

Publication Number Publication Date
ATE384001T1 true ATE384001T1 (de) 2008-02-15

Family

ID=31981380

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07119781T ATE503687T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis
AT03791745T ATE384001T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von dosierinhalatorformulierungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT07119781T ATE503687T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis

Country Status (14)

Country Link
US (3) US20040042973A1 (de)
EP (2) EP1878664B1 (de)
JP (3) JP4679901B2 (de)
AT (2) ATE503687T1 (de)
AU (1) AU2003265639A1 (de)
CA (1) CA2495875C (de)
CY (1) CY1107376T1 (de)
DE (2) DE60318727T2 (de)
DK (1) DK1542904T3 (de)
ES (1) ES2297262T3 (de)
MX (1) MXPA05002248A (de)
PT (1) PT1542904E (de)
SI (1) SI1542904T1 (de)
WO (1) WO2004020289A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0207906D0 (en) 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
ES2388537T3 (es) * 2002-08-23 2012-10-16 Merck Sharp & Dohme Corp. Inhalador dosificador que contiene una formulación en suspensión de aerosol
CN1870976A (zh) * 2003-10-20 2006-11-29 先灵公司 药物组合物
SE0401408D0 (sv) * 2004-06-02 2004-06-02 Astrazeneca Ab Diameter measuring device
DE602005009012D1 (de) * 2004-10-12 2008-09-25 Generics Uk Ltd Rmulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
WO2008047149A1 (en) * 2006-10-19 2008-04-24 Cipla Limited Pharmaceutical compositions and nasal spray incorporating anhydrous mometasone furoate
US20080253970A1 (en) * 2007-02-09 2008-10-16 Schering Corporation Stable Pharmaceutical Drug Products
BRPI0721256A2 (pt) 2007-02-09 2013-03-12 Schering Corp aerossàis de fÁrmaco farmacÊuticos estÁveis
HUE027718T2 (en) 2009-05-12 2016-10-28 Galenica Ab Oil-in-water emulsion containing mometasone and propylene glycol
US20120128736A1 (en) * 2009-05-12 2012-05-24 Galenica Ab Oil-in-water emulsion of mometasone
AU2015200276B2 (en) * 2010-02-10 2016-01-21 Astrazeneca Uk Limited A filled canister for an inhaler
CN102858640B (zh) * 2010-02-10 2015-12-09 阿斯利康英国有限公司 提供用于吸入器的填充罐的方法
CN107626019A (zh) * 2016-07-18 2018-01-26 卓效医疗有限公司 手持式喷雾器
CN107951893B (zh) * 2016-10-18 2022-04-26 天津金耀集团有限公司 一种糠酸莫米松粉吸入剂组合物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592319A (en) * 1968-10-28 1971-07-13 Roy S Rousseau Article feed control
US3835898A (en) * 1972-11-13 1974-09-17 Kartridg Pak Co Remotely adjustable filling head
US4793461A (en) * 1987-02-26 1988-12-27 The Kartridg Pak Co. Container feed apparatus
US5143260A (en) * 1990-06-05 1992-09-01 Nozone Dispenser Systems, Inc. Aerosol adapter clamp and power system
US5182097A (en) * 1991-02-14 1993-01-26 Virginia Commonwealth University Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
ATE339952T1 (de) * 1991-06-10 2006-10-15 Schering Corp Fluorchlorkohlenwasserstofffreie aerosolformulierungen
CA2111002C (en) * 1991-06-10 2000-08-22 Julianne Fassberg Non-chlorofluorocarbon aerosol formulations
US5275212A (en) * 1993-02-24 1994-01-04 Minnesota Mining And Manufacturing Company Aerosol filling method
GB9612297D0 (en) * 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
US5698161A (en) 1996-08-26 1997-12-16 Michigan Critical Care Consultants, Inc. Hollow, multi-dimensional array membrane
CZ294064B6 (cs) * 1996-08-29 2004-09-15 Schering Corporation Aerosolový suspenzní přípravek mometazonfuroátu bez chlorfluorovaných uhlovodíků
US6068832A (en) * 1996-08-29 2000-05-30 Schering Corporation Chlorofluorocarbon-free mometasone furoate aerosol formulations
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
GB9904919D0 (en) * 1999-03-03 1999-04-28 Novartis Ag Organic compounds
AU2206801A (en) * 1999-12-24 2001-07-09 Alan Leslie Cripps Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
AU2001278115A1 (en) 2000-08-04 2002-02-18 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
ITMI20010428A1 (it) * 2001-03-02 2002-09-02 Chemo Breath S A Composizioni ad uso inalatorio a base di formoterolo
AR036358A1 (es) * 2001-08-28 2004-09-01 Schering Corp Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma
GB0207906D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
ES2388537T3 (es) * 2002-08-23 2012-10-16 Merck Sharp & Dohme Corp. Inhalador dosificador que contiene una formulación en suspensión de aerosol
CN1870976A (zh) * 2003-10-20 2006-11-29 先灵公司 药物组合物
CA2641616A1 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
US20080253970A1 (en) * 2007-02-09 2008-10-16 Schering Corporation Stable Pharmaceutical Drug Products

Also Published As

Publication number Publication date
SI1542904T1 (sl) 2008-06-30
AU2003265639A1 (en) 2004-03-19
JP4679901B2 (ja) 2011-05-11
EP1542904B1 (de) 2008-01-16
EP1542904A1 (de) 2005-06-22
JP2005537095A (ja) 2005-12-08
DK1542904T3 (da) 2008-04-21
CA2495875C (en) 2010-06-22
EP1878664B1 (de) 2011-03-30
ATE503687T1 (de) 2011-04-15
US20130068218A1 (en) 2013-03-21
MXPA05002248A (es) 2005-06-08
US20040042973A1 (en) 2004-03-04
PT1542904E (pt) 2008-03-24
CY1107376T1 (el) 2012-12-19
CA2495875A1 (en) 2004-03-11
DE60336602D1 (de) 2011-05-12
DE60318727T2 (de) 2009-01-08
US20080066744A1 (en) 2008-03-20
ES2297262T3 (es) 2008-05-01
JP2011046726A (ja) 2011-03-10
EP1878664A1 (de) 2008-01-16
JP2006305390A (ja) 2006-11-09
DE60318727D1 (de) 2008-03-06
WO2004020289A1 (en) 2004-03-11

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