ATE384001T1 - Verfahren zur herstellung von dosierinhalatorformulierungen - Google Patents

Verfahren zur herstellung von dosierinhalatorformulierungen

Info

Publication number
ATE384001T1
ATE384001T1 AT03791745T AT03791745T ATE384001T1 AT E384001 T1 ATE384001 T1 AT E384001T1 AT 03791745 T AT03791745 T AT 03791745T AT 03791745 T AT03791745 T AT 03791745T AT E384001 T1 ATE384001 T1 AT E384001T1
Authority
AT
Austria
Prior art keywords
metered dose
dose inhaler
container
suspension
solution
Prior art date
Application number
AT03791745T
Other languages
English (en)
Inventor
Saeed Chaudhry
Stefan Sharpe
Julianne Berry
Joel Sequeira
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE384001T1 publication Critical patent/ATE384001T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/003—Adding propellants in fluid form to aerosol containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT03791745T 2002-08-27 2003-08-26 Verfahren zur herstellung von dosierinhalatorformulierungen ATE384001T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40612702P 2002-08-27 2002-08-27
US42243602P 2002-10-30 2002-10-30

Publications (1)

Publication Number Publication Date
ATE384001T1 true ATE384001T1 (de) 2008-02-15

Family

ID=31981380

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07119781T ATE503687T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis
AT03791745T ATE384001T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von dosierinhalatorformulierungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT07119781T ATE503687T1 (de) 2002-08-27 2003-08-26 Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis

Country Status (14)

Country Link
US (3) US20040042973A1 (de)
EP (2) EP1542904B1 (de)
JP (3) JP4679901B2 (de)
AT (2) ATE503687T1 (de)
AU (1) AU2003265639A1 (de)
CA (1) CA2495875C (de)
CY (1) CY1107376T1 (de)
DE (2) DE60336602D1 (de)
DK (1) DK1542904T3 (de)
ES (1) ES2297262T3 (de)
MX (1) MXPA05002248A (de)
PT (1) PT1542904E (de)
SI (1) SI1542904T1 (de)
WO (1) WO2004020289A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0207906D0 (en) 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
CA2495689A1 (en) * 2002-08-23 2004-03-04 Schering Corporation Pharmaceutical compositions
CA2542530A1 (en) * 2003-10-20 2005-05-12 Schering Corporation Pharmaceutical aerosol compositions
SE0401408D0 (sv) * 2004-06-02 2004-06-02 Astrazeneca Ab Diameter measuring device
EP1811981B1 (de) * 2004-10-12 2008-08-13 Merck Generics (UK) Limited Verfahren zur herstellung von suspensionsaerosolformulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
US20090325917A1 (en) * 2006-10-19 2009-12-31 Cipla Limited Pharmaceutical Compositions and Nasal Spray Incorporating Anhydrous Mometasone Furoate
US20080253970A1 (en) * 2007-02-09 2008-10-16 Schering Corporation Stable Pharmaceutical Drug Products
EP2117504A1 (de) 2007-02-09 2009-11-18 Schering Corporation Stabile pharmazeutische wirkstoff-aerosole
WO2010130428A1 (en) 2009-05-12 2010-11-18 Galenica Ab Oil-in-water emulsion of mometasone and propylene glycol
SMT201700066T1 (it) * 2009-05-12 2017-05-08 Galenica Ab Emulsione olio-in-acqua di mometasone
AU2015200276B2 (en) * 2010-02-10 2016-01-21 Astrazeneca Uk Limited A filled canister for an inhaler
WO2011098798A1 (en) * 2010-02-10 2011-08-18 Astrazeneca Uk Limited Process for providing a filled canister for an inhaler
CN107626019A (zh) * 2016-07-18 2018-01-26 卓效医疗有限公司 手持式喷雾器
CN107951893B (zh) * 2016-10-18 2022-04-26 天津金耀集团有限公司 一种糠酸莫米松粉吸入剂组合物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592319A (en) * 1968-10-28 1971-07-13 Roy S Rousseau Article feed control
US3835898A (en) * 1972-11-13 1974-09-17 Kartridg Pak Co Remotely adjustable filling head
US4793461A (en) * 1987-02-26 1988-12-27 The Kartridg Pak Co. Container feed apparatus
US5143260A (en) * 1990-06-05 1992-09-01 Nozone Dispenser Systems, Inc. Aerosol adapter clamp and power system
US5182097A (en) * 1991-02-14 1993-01-26 Virginia Commonwealth University Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
DK1277467T3 (da) * 1991-06-10 2007-01-15 Schering Corp Formuleringer af ikke-chlorfluorcarbonaerosoler
ES2200771T3 (es) * 1991-06-10 2004-03-16 Schering Corporation Formulaciones en aerosol no clorofluorocarbonadas.
US5275212A (en) * 1993-02-24 1994-01-04 Minnesota Mining And Manufacturing Company Aerosol filling method
GB9612297D0 (en) 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
US5698161A (en) 1996-08-26 1997-12-16 Michigan Critical Care Consultants, Inc. Hollow, multi-dimensional array membrane
US6068832A (en) * 1996-08-29 2000-05-30 Schering Corporation Chlorofluorocarbon-free mometasone furoate aerosol formulations
EP0927037B1 (de) * 1996-08-29 2001-07-11 Schering Corporation Chlorfluorkohlenwasserstoff freie aerosol-arzneizubereitungen enthaltend mometasonfuroat
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
GB9904919D0 (en) * 1999-03-03 1999-04-28 Novartis Ag Organic compounds
EP1248597B1 (de) * 1999-12-24 2005-03-30 Glaxo Group Limited Pharmazeutische aerosol formulierung enthaltend salmeterol und fluticason
AU2001278115A1 (en) * 2000-08-04 2002-02-18 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
ITMI20010428A1 (it) * 2001-03-02 2002-09-02 Chemo Breath S A Composizioni ad uso inalatorio a base di formoterolo
TWI324934B (en) * 2001-08-28 2010-05-21 Schering Corp Pharmaceutical compositions for the treatment of asthma
GB0207906D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
CA2495689A1 (en) * 2002-08-23 2004-03-04 Schering Corporation Pharmaceutical compositions
CA2542530A1 (en) * 2003-10-20 2005-05-12 Schering Corporation Pharmaceutical aerosol compositions
EP1981545A2 (de) * 2006-02-09 2008-10-22 Schering Corporation Pharmazeutische formulierungen
US20080253970A1 (en) * 2007-02-09 2008-10-16 Schering Corporation Stable Pharmaceutical Drug Products

Also Published As

Publication number Publication date
DK1542904T3 (da) 2008-04-21
US20040042973A1 (en) 2004-03-04
DE60318727T2 (de) 2009-01-08
US20080066744A1 (en) 2008-03-20
DE60336602D1 (de) 2011-05-12
SI1542904T1 (sl) 2008-06-30
JP2011046726A (ja) 2011-03-10
WO2004020289A1 (en) 2004-03-11
US20130068218A1 (en) 2013-03-21
JP2006305390A (ja) 2006-11-09
ES2297262T3 (es) 2008-05-01
EP1878664A1 (de) 2008-01-16
EP1878664B1 (de) 2011-03-30
JP2005537095A (ja) 2005-12-08
CY1107376T1 (el) 2012-12-19
MXPA05002248A (es) 2005-06-08
CA2495875A1 (en) 2004-03-11
CA2495875C (en) 2010-06-22
AU2003265639A1 (en) 2004-03-19
EP1542904B1 (de) 2008-01-16
PT1542904E (pt) 2008-03-24
DE60318727D1 (de) 2008-03-06
ATE503687T1 (de) 2011-04-15
JP4679901B2 (ja) 2011-05-11
EP1542904A1 (de) 2005-06-22

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