ATE384524T1 - Nitroimidazolpräparationen zur äusseren anwendung zur behandlung von atopischer dermatitis - Google Patents
Nitroimidazolpräparationen zur äusseren anwendung zur behandlung von atopischer dermatitisInfo
- Publication number
- ATE384524T1 ATE384524T1 AT00946319T AT00946319T ATE384524T1 AT E384524 T1 ATE384524 T1 AT E384524T1 AT 00946319 T AT00946319 T AT 00946319T AT 00946319 T AT00946319 T AT 00946319T AT E384524 T1 ATE384524 T1 AT E384524T1
- Authority
- AT
- Austria
- Prior art keywords
- nitroimidazole
- group
- preparations
- treatment
- atopic dermatitis
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 title 1
- 206010012438 Dermatitis atopic Diseases 0.000 title 1
- 201000008937 atopic dermatitis Diseases 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 150000004957 nitroimidazoles Chemical class 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23449699 | 1999-07-16 | ||
| JP11206508 | 1999-07-21 | ||
| JP11271077 | 1999-09-24 | ||
| JP31284099 | 1999-09-28 | ||
| JP2000042012 | 2000-01-14 | ||
| JP2000067746 | 2000-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384524T1 true ATE384524T1 (de) | 2008-02-15 |
Family
ID=27553827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00946319T ATE384524T1 (de) | 1999-07-16 | 2000-07-14 | Nitroimidazolpräparationen zur äusseren anwendung zur behandlung von atopischer dermatitis |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20030092754A1 (de) |
| EP (1) | EP1206937B1 (de) |
| KR (1) | KR100671879B1 (de) |
| CN (1) | CN1304001C (de) |
| AT (1) | ATE384524T1 (de) |
| AU (1) | AU773881B2 (de) |
| CA (1) | CA2379270C (de) |
| DE (1) | DE60037892T2 (de) |
| HK (1) | HK1046639B (de) |
| WO (1) | WO2001005400A1 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20030206965A1 (en) * | 2000-09-29 | 2003-11-06 | The Procter & Gamble Company | Allergen neutralization compositions |
| IL142037A0 (en) * | 2001-03-15 | 2002-03-10 | Agis Ind 1983 Ltd | Pharmaceutical compositions containing a non-steroidal anti-inflammatory drug |
| US7658941B2 (en) | 2002-05-01 | 2010-02-09 | Johnson & Johnson Consumer Companies, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US7417013B2 (en) | 2002-05-01 | 2008-08-26 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
| KR20050025166A (ko) * | 2002-05-01 | 2005-03-11 | 맥네일-피피씨, 인코포레이티드 | 가온성 및 무자극성 윤활제 항진균성 겔 조성물 |
| US20040167039A1 (en) * | 2002-05-01 | 2004-08-26 | Nawaz Ahmad | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US7005408B2 (en) * | 2002-05-01 | 2006-02-28 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US20040185065A1 (en) * | 2002-05-01 | 2004-09-23 | Nawaz Ahmad | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US7695730B2 (en) | 2002-05-01 | 2010-04-13 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US20030215397A1 (en) * | 2002-05-14 | 2003-11-20 | Noah Patricia W. | Method of treatment of skin diseases related to microbial antigens in the skin |
| CA2496864C (en) | 2002-08-26 | 2009-04-28 | S.L.A. Pharma Ag | A pharmaceutical composition |
| FR2851470B1 (fr) * | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
| US7238212B2 (en) * | 2003-06-02 | 2007-07-03 | L'oreal, S.A. | Imidazole compounds and use of these compounds for dyeing keratinous fibers |
| FR2866570B1 (fr) * | 2004-02-20 | 2007-08-24 | Galderma Res & Dev | Utilisation du metronidazole pour la preparation d'une composition pharmaceutique destinee a traiter une inflammation cutanee |
| FR2866569B1 (fr) * | 2004-02-20 | 2007-08-24 | Galderma Res & Dev | Utilisation du metronidazole pour la preparation d'une composition pharmaceutique destinee a traiter des pathologies liees au recepteur de type b de l'interleukine 8 et/ou au recepteur de type 1 de pacap |
| US20060040002A1 (en) * | 2004-08-17 | 2006-02-23 | Boitano Suzanne M | Anti-itch composition |
| US20070237809A1 (en) * | 2004-08-30 | 2007-10-11 | Phaneuf Matthew D | Multi-functional bioactive wound dressing |
| US20060093675A1 (en) * | 2004-10-29 | 2006-05-04 | Mathew Ebmeier | Intravaginal treatment of vaginal infections with metronidazole compositions |
| US7851419B2 (en) | 2005-09-12 | 2010-12-14 | Nawaz Ahmad | Substantially anhydrous sprayable personal lubricant |
| US7320801B2 (en) * | 2005-09-26 | 2008-01-22 | Jack Perez Kelly | Patch for treating symptoms of a skin abscess |
| US8147815B2 (en) * | 2005-12-16 | 2012-04-03 | Celmatrix Corporation | Topical administration carrier composition and therapeutic formulations comprising same |
| US20070179121A1 (en) * | 2006-02-02 | 2007-08-02 | Plott R T | Method of treating pediatric patients with corticosteroids |
| FR2899475A1 (fr) * | 2006-04-10 | 2007-10-12 | Galderma Res & Dev | Composition pharmaceutique pour le traitement de la rosacee |
| US20080063668A1 (en) * | 2006-09-12 | 2008-03-13 | Borgman Robert J | Nitroimidazole and terconazole composition and method |
| FR2909876A1 (fr) * | 2006-12-19 | 2008-06-20 | Galderma Res & Dev S N C Snc | Utilisation du nepafenac ou ses derives pour le traitement de desordres dermatologiques |
| US7758901B2 (en) * | 2007-02-16 | 2010-07-20 | Betty Bellman | Compositions and methods for alleviating skin disorders |
| US7488500B2 (en) * | 2007-02-16 | 2009-02-10 | Betty Bellman | Compositions and methods for alleviating skin disorders |
| US9011943B2 (en) * | 2007-02-16 | 2015-04-21 | Skin Evolution LLC | Compositions and methods for alleviating skin disorders |
| US20100105750A1 (en) * | 2008-10-23 | 2010-04-29 | Nycomed Us Inc. | Stable metronidazole gel formulations |
| IT1396731B1 (it) * | 2009-11-25 | 2012-12-14 | Masci | Composizione farmaceutica a base di metronidazolo ed ossido di zinco per il trattamento topico di patologie anali acute e croniche distrofiche e post-operatorie |
| AU2015244700B2 (en) | 2014-04-10 | 2020-08-27 | Riken | Compositions and methods for induction of Th17 cells |
| CN104147044B (zh) * | 2014-08-28 | 2017-02-22 | 湖南农业大学 | 一种治疗仔猪葡萄球菌性渗出性皮炎的组合物 |
| KR20170052626A (ko) | 2014-09-05 | 2017-05-12 | 심바이오믹스 세러퓨틱스 엘엘씨 | 세균질증 치료에 사용하기 위한 세크니다졸 |
| US11253501B2 (en) | 2015-06-01 | 2022-02-22 | Lupin Inc. | Secnidazole formulations and use in treating bacterial vaginosis |
| US9962444B2 (en) | 2016-09-27 | 2018-05-08 | Shane Malek | Pharmacokinetically extended action topical hair growth formulation, and administration method |
| CN106580978A (zh) * | 2016-11-30 | 2017-04-26 | 郑州仁宏医药科技有限公司 | 一种治疗皮炎的西药组合物及其应用 |
| TWI820142B (zh) | 2018-05-29 | 2023-11-01 | 日商大塚製藥工場股份有限公司 | 外用組成物 |
| CN108503589B (zh) * | 2018-06-20 | 2021-05-14 | 徐州工业职业技术学院 | 一种硝酸益康唑的制备方法 |
| US20220288038A1 (en) * | 2019-08-21 | 2022-09-15 | The University Of Tokyo | Abcc11 inhibitor |
| CN110773086B (zh) * | 2019-11-20 | 2025-05-13 | 黄冈银河阿迪药业有限公司 | 模拟临界状态雾化流羟化合成甲硝唑的装置及其合成方法 |
| US12280037B2 (en) | 2020-09-22 | 2025-04-22 | Evofem Biosciences, Inc. | Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof |
| CN112138015B (zh) * | 2020-10-22 | 2022-08-05 | 合肥博思科创医药科技有限公司 | 三苄糖苷在治疗微循环障碍引起的皮肤疾病中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4491588A (en) * | 1982-03-31 | 1985-01-01 | University Of Tennessee Research Corporation | Treatment of psoriasis and seborrheic dermatitis with imidazole antibiotics |
| US4537776A (en) * | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
| US4837378A (en) * | 1986-01-15 | 1989-06-06 | Curatek Pharmaceuticals, Inc. | Topical metronidazole formulations and therapeutic uses thereof |
| US4957918A (en) * | 1988-06-09 | 1990-09-18 | Leonard Bloom | Topical treatment of blepharitis |
| CN1068038A (zh) * | 1991-06-27 | 1993-01-20 | 杨昌道 | 足癣膏的配方及制作方法 |
| SE506509C2 (sv) * | 1992-04-14 | 1997-12-22 | Bioglan Ab | Användning av imidazoler för framställning av en farmaceutisk formulering för behandling av inflammatoriska och/eller infektiösa hudsjukdomar |
| RU2080864C1 (ru) * | 1993-11-09 | 1997-06-10 | Евгений Владимирович Намоконов | Средство для лечения гнойных ран |
| JPH07179341A (ja) * | 1993-12-22 | 1995-07-18 | Toko Yakuhin Kogyo Kk | 安定なミコフェノール酸含有皮膚外用剤 |
| FR2722098B1 (fr) * | 1994-07-06 | 1996-08-23 | Cird Galderma | Nouveaux medicaments a base de metro-nidazole ou d'un melange synergetique de metronidazole et de clindamycine |
| CN1137890A (zh) * | 1995-06-10 | 1996-12-18 | 董闽安 | 一种消除痤疮及其沉积色素的美容品青春霜和加工方法 |
| CA2161737C (en) * | 1995-10-30 | 1998-10-20 | Richard J. Mackay | Metronidazole gel |
| GB9626513D0 (en) * | 1996-12-20 | 1997-02-05 | Bioglan Ireland R & D Ltd | A pharmaceutical composition |
| US6482839B1 (en) * | 1997-06-02 | 2002-11-19 | Cellegy Pharmaceuticals, Inc. | Pyridine-thiols for treatment of a follicular dermatosis |
| AU8588898A (en) * | 1997-07-28 | 1999-02-16 | Mary L. Redmond | Composition and process for the treatment of epidermal traumas such as decubitusulcers |
| EP0995781B1 (de) * | 1998-04-23 | 2004-08-18 | Idemitsu Petrochemical Co., Ltd. | Beschichtungszusammensetzung |
| CN1090936C (zh) * | 1999-05-19 | 2002-09-18 | 张广政 | 一种治疗痤疮的复合制剂 |
-
2000
- 2000-07-14 EP EP00946319A patent/EP1206937B1/de not_active Expired - Lifetime
- 2000-07-14 HK HK02108189.2A patent/HK1046639B/zh not_active IP Right Cessation
- 2000-07-14 DE DE60037892T patent/DE60037892T2/de not_active Expired - Lifetime
- 2000-07-14 AT AT00946319T patent/ATE384524T1/de active
- 2000-07-14 WO PCT/JP2000/004728 patent/WO2001005400A1/ja not_active Ceased
- 2000-07-14 CA CA002379270A patent/CA2379270C/en not_active Expired - Fee Related
- 2000-07-14 CN CNB008103682A patent/CN1304001C/zh not_active Expired - Fee Related
- 2000-07-14 AU AU60161/00A patent/AU773881B2/en not_active Ceased
- 2000-07-14 KR KR1020027000421A patent/KR100671879B1/ko not_active Expired - Fee Related
-
2002
- 2002-01-16 US US10/046,575 patent/US20030092754A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1304001C (zh) | 2007-03-14 |
| WO2001005400A1 (en) | 2001-01-25 |
| KR20020020780A (ko) | 2002-03-15 |
| HK1046639B (zh) | 2007-10-05 |
| CN1361688A (zh) | 2002-07-31 |
| KR100671879B1 (ko) | 2007-01-19 |
| HK1046639A1 (en) | 2003-01-24 |
| US20030092754A1 (en) | 2003-05-15 |
| DE60037892T2 (de) | 2009-01-15 |
| AU6016100A (en) | 2001-02-05 |
| AU773881B2 (en) | 2004-06-10 |
| EP1206937A4 (de) | 2005-01-19 |
| EP1206937B1 (de) | 2008-01-23 |
| CA2379270A1 (en) | 2001-01-25 |
| CA2379270C (en) | 2007-04-10 |
| DE60037892D1 (de) | 2008-03-13 |
| EP1206937A1 (de) | 2002-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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