ATE384784T1 - Verfahren zur produktion von adenovirus - Google Patents
Verfahren zur produktion von adenovirusInfo
- Publication number
- ATE384784T1 ATE384784T1 AT00973440T AT00973440T ATE384784T1 AT E384784 T1 ATE384784 T1 AT E384784T1 AT 00973440 T AT00973440 T AT 00973440T AT 00973440 T AT00973440 T AT 00973440T AT E384784 T1 ATE384784 T1 AT E384784T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- culture
- medium
- growth
- adenoviral vectors
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 title 1
- 239000013598 vector Substances 0.000 abstract 5
- 239000002609 medium Substances 0.000 abstract 4
- 238000012258 culturing Methods 0.000 abstract 2
- 239000012737 fresh medium Substances 0.000 abstract 2
- 230000005526 G1 to G0 transition Effects 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000010412 perfusion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polarising Elements (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/545,385 US6168941B1 (en) | 2000-04-07 | 2000-04-07 | Method of producing adenoviral vector stocks |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384784T1 true ATE384784T1 (de) | 2008-02-15 |
Family
ID=24175996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00973440T ATE384784T1 (de) | 2000-04-07 | 2000-10-10 | Verfahren zur produktion von adenovirus |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6168941B1 (de) |
| EP (1) | EP1268748B1 (de) |
| JP (1) | JP4662525B2 (de) |
| AT (1) | ATE384784T1 (de) |
| AU (1) | AU2001211944A1 (de) |
| CA (1) | CA2400746A1 (de) |
| DE (1) | DE60037911T2 (de) |
| DK (1) | DK1268748T3 (de) |
| ES (1) | ES2296653T3 (de) |
| WO (1) | WO2001077304A1 (de) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6821775B1 (en) * | 2000-02-11 | 2004-11-23 | Genvec, Inc. | Viral vector encoding pigment epithelium-derived factor |
| US7653769B2 (en) * | 2006-12-14 | 2010-01-26 | International Business Machines Corporation | Management of devices connected to infiniband ports |
| US6591543B2 (en) * | 2000-04-14 | 2003-07-15 | Kenneth P. Sabine | Top water lure with highly active propeller |
| US20030087438A1 (en) * | 2001-11-02 | 2003-05-08 | Genvec, Inc. | E1-revertant-free adenoviral composition |
| AU2002348151A1 (en) * | 2001-11-05 | 2003-05-19 | Genvec, Inc. | Viral vector production methods and compositions |
| CA2468970A1 (en) * | 2001-11-29 | 2003-06-05 | Yoshinobu Konno | Process for producing substance |
| US20030158112A1 (en) * | 2002-02-15 | 2003-08-21 | Johns Hopkins University School Of Medicine | Selective induction of apoptosis to treat ocular disease |
| JP2006516027A (ja) * | 2002-12-02 | 2006-06-15 | ジェンベク、インコーポレイティッド | 眼関連障害の治療用材料および治療方法 |
| US20040166091A1 (en) | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| US20040229335A1 (en) | 2003-05-15 | 2004-11-18 | Introgen Therapeutics, Inc. | Methods and compositions for the production of adenoviral vectors |
| WO2005012537A2 (en) * | 2003-07-25 | 2005-02-10 | Genvec, Inc. | Adenoviral vector-based vaccines |
| DE602004025726D1 (de) * | 2003-11-14 | 2010-04-08 | Genvec Inc | Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc). |
| EP1697505A1 (de) * | 2003-12-23 | 2006-09-06 | Schering Corporation | Methoden zur herstellung von a549 zelllinien, die in serumfreiem medium in suspensionskultur stabil sind |
| US20070207461A1 (en) * | 2004-02-23 | 2007-09-06 | Crucell Holland B.V. | Virus Purification Methods |
| CA2557046A1 (en) | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
| WO2005089811A1 (en) * | 2004-03-12 | 2005-09-29 | Genvec, Inc. | Materials for treating vascular leakage in the eye |
| AU2005243730B2 (en) | 2004-04-12 | 2010-05-27 | Genvec, Inc. | Method of using adenoviral vectors to induce an immune response |
| EP1784493A2 (de) * | 2004-09-01 | 2007-05-16 | The Government of the United States of America as Represented by The Department of Health and Human Services | Adenovirale vektoren mit der fähigkeit zum umwandeln von apcs, mögliche verwendung bei immunantworterzeugung |
| US20060188481A1 (en) * | 2005-02-22 | 2006-08-24 | Saitama Medical School | Methods for prophylactically or therapeutically treating an animal for an ocular-related disorder |
| JP5225069B2 (ja) | 2005-03-23 | 2013-07-03 | ゲンマブ エー／エス | 多発性骨髄腫の治療のためのｃｄ３８に対する抗体 |
| CA2602944C (en) * | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| US9651543B2 (en) | 2005-08-31 | 2017-05-16 | The United States Of America As Represented By The Secretary Of The Navy | Malaria antigen screening method |
| US8450055B2 (en) | 2005-08-31 | 2013-05-28 | The United States Of America As Represented By The Secretary Of The Navy | Malaria antigen screening method |
| BRPI0618441B8 (pt) * | 2005-11-10 | 2021-07-27 | Genvec Inc | vetor adenoviral |
| KR101685246B1 (ko) | 2006-07-14 | 2016-12-09 | 디피엑스 홀딩스 비.브이. | 개선된 세포 배양 방법 |
| EP2612867A1 (de) | 2007-11-01 | 2013-07-10 | Perseid Therapeutics LLC | Immunsuppressive Polypeptide und Nucleinsäuren |
| SG187397A1 (en) * | 2007-12-27 | 2013-02-28 | Baxter Int | Cell culture processes |
| US9605844B2 (en) * | 2009-09-01 | 2017-03-28 | Cree, Inc. | Lighting device with heat dissipation elements |
| JP6009357B2 (ja) * | 2010-01-12 | 2016-10-19 | バスキュラー バイオジェニックス リミテッド | アデノウイルスベクターの生産方法およびそれによって生成されるウイルス調製物 |
| WO2013012770A2 (en) * | 2011-07-19 | 2013-01-24 | Wenlin Huang | Process for producing recombinant human endostatin adenovirus |
| US11390663B2 (en) | 2013-10-11 | 2022-07-19 | Regeneron Pharmaceuticals, Inc. | Metabolically optimized cell culture |
| JP7242180B2 (ja) | 2014-09-07 | 2023-03-20 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物 |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| MX2019008143A (es) | 2017-01-07 | 2020-01-13 | Selecta Biosciences Inc | Dosificación sistemática de inmunosupresores acoplados a nanoportadores sintéticos. |
| US11609120B2 (en) * | 2017-10-06 | 2023-03-21 | Lonza Ltd | Automated control of cell culture using Raman spectroscopy |
| BR112020007157A2 (pt) | 2017-10-13 | 2020-09-24 | Selecta Biosciences, Inc. | métodos e composições para a atenuação de respostas de igm antivetor de transferência viral |
| EP3962537A1 (de) | 2019-04-28 | 2022-03-09 | Selecta Biosciences, Inc. | Verfahren zur behandlung von subjekten mit vorbestehender immunität gegen virusübertragungsvektoren |
| CN114206396A (zh) | 2019-05-28 | 2022-03-18 | 西莱克塔生物科技公司 | 用于减弱抗病毒转移载体免疫应答的方法和组合物 |
| CN118767143A (zh) | 2019-12-12 | 2024-10-15 | 听治疗有限责任公司 | 用于预防和治疗听力损失的组合物和方法 |
| US20230141563A1 (en) | 2021-10-12 | 2023-05-11 | Selecta Biosciences, Inc. | Methods and compositions for attenuating anti-viral transfer vector igm responses |
| WO2023172624A1 (en) | 2022-03-09 | 2023-09-14 | Selecta Biosciences, Inc. | Immunosuppressants in combination with anti-igm agents and related dosing |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117881A (en) | 1977-06-14 | 1978-10-03 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | System for and method of freezing biological tissue |
| US4327799A (en) | 1979-06-18 | 1982-05-04 | Helmholtz-Institut Fur Biomedizinische Technik | Process and apparatus for freezing living cells |
| US4304293A (en) | 1979-06-18 | 1981-12-08 | Helmholtz-Institut Fur Biomedizinische Technik | Process and apparatus for freezing living cells |
| US4455842A (en) | 1981-07-15 | 1984-06-26 | Biotech Research Laboratories, Inc. | Device and method for controlled freezing of cell cultures |
| US4377077A (en) | 1981-07-15 | 1983-03-22 | Biotech Research Laboratories, Inc. | Device and method for controlled freezing of cell cultures |
| US4676070A (en) | 1984-11-30 | 1987-06-30 | The Board Of Regents, The University Of Texas | Apparatus and method for cryopreparing biological tissue |
| US7732129B1 (en) | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| WO1998022588A2 (en) * | 1996-11-20 | 1998-05-28 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| US5994134A (en) | 1998-05-04 | 1999-11-30 | Canji, Inc. | Viral production process |
-
2000
- 2000-04-07 US US09/545,385 patent/US6168941B1/en not_active Expired - Lifetime
- 2000-10-10 ES ES00973440T patent/ES2296653T3/es not_active Expired - Lifetime
- 2000-10-10 DE DE60037911T patent/DE60037911T2/de not_active Expired - Fee Related
- 2000-10-10 AU AU2001211944A patent/AU2001211944A1/en not_active Abandoned
- 2000-10-10 WO PCT/US2000/027946 patent/WO2001077304A1/en not_active Ceased
- 2000-10-10 DK DK00973440T patent/DK1268748T3/da active
- 2000-10-10 JP JP2001575158A patent/JP4662525B2/ja not_active Expired - Lifetime
- 2000-10-10 CA CA002400746A patent/CA2400746A1/en not_active Abandoned
- 2000-10-10 EP EP00973440A patent/EP1268748B1/de not_active Expired - Lifetime
- 2000-10-10 AT AT00973440T patent/ATE384784T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6168941B1 (en) | 2001-01-02 |
| ES2296653T3 (es) | 2008-05-01 |
| EP1268748B1 (de) | 2008-01-23 |
| DK1268748T3 (da) | 2008-06-02 |
| JP4662525B2 (ja) | 2011-03-30 |
| WO2001077304A1 (en) | 2001-10-18 |
| CA2400746A1 (en) | 2001-10-18 |
| EP1268748A1 (de) | 2003-01-02 |
| JP2003530104A (ja) | 2003-10-14 |
| DE60037911T2 (de) | 2009-01-08 |
| DE60037911D1 (de) | 2008-03-13 |
| AU2001211944A1 (en) | 2001-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1268748 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |