ATE385235T1 - Tricyclische spiropiperidine oder spiropyrrolidine - Google Patents

Tricyclische spiropiperidine oder spiropyrrolidine

Info

Publication number: ATE385235T1
Authority: AT; Austria
Prior art keywords: spiropyrrolidine; spiropiperidine; tricyclic; tricyclic spiropiperidine
Prior art date: 2002-07-08

Application number

AT03762957T

Other languages

English (en)

Inventor

Nafizal Hossain

Svetlana Ivanova

Marguerite Mensonides-Harsema

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-08

Filing date

2003-07-07

Publication date

2008-02-15

2003-07-07 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2008-02-15 Application granted granted Critical

2008-02-15 Publication of ATE385235T1 publication Critical patent/ATE385235T1/de

Links

JUXAVSAMVBLDKO-UHFFFAOYSA-N 1-(1-azabicyclo[2.2.2]octan-3-yl)-3-[3-(1h-indol-3-yl)-1-oxo-1-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropan-2-yl]urea Chemical compound C1N(CC2)CCC2C1NC(=O)NC(C(=O)N1CCC2(C3=CC=CC=C3CC2)CC1)CC1=CNC2=CC=CC=C12 JUXAVSAMVBLDKO-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT03762957T 2002-07-08 2003-07-07 Tricyclische spiropiperidine oder spiropyrrolidine ATE385235T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE0202133A SE0202133D0 (sv)	2002-07-08	2002-07-08	Novel compounds

Publications (1)

Publication Number	Publication Date
ATE385235T1 true ATE385235T1 (de)	2008-02-15

Family

ID=20288470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03762957T ATE385235T1 (de)	2002-07-08	2003-07-07	Tricyclische spiropiperidine oder spiropyrrolidine

Country Status (25)

Country	Link
US (2)	US7449475B2 (de)
EP (1)	EP1521757B1 (de)
JP (1)	JP2005537255A (de)
CN (2)	CN1326858C (de)
AR (1)	AR040475A1 (de)
AT (1)	ATE385235T1 (de)
AU (1)	AU2003243122B2 (de)
BR (1)	BR0312560A (de)
CA (1)	CA2492122A1 (de)
CY (1)	CY1107915T1 (de)
DE (1)	DE60318948T2 (de)
DK (1)	DK1521757T3 (de)
ES (1)	ES2298575T3 (de)
IS (1)	IS7662A (de)
MX (1)	MXPA05000278A (de)
NO (1)	NO20050635L (de)
NZ (1)	NZ537259A (de)
PL (1)	PL374877A1 (de)
PT (1)	PT1521757E (de)
RU (1)	RU2320664C2 (de)
SE (1)	SE0202133D0 (de)
TW (1)	TW200413386A (de)
UA (1)	UA77809C2 (de)
WO (1)	WO2004005295A1 (de)
ZA (1)	ZA200500024B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0202133D0 (sv)	2002-07-08	2002-07-08	Astrazeneca Ab	Novel compounds
US7732442B2 (en)	2003-09-05	2010-06-08	Ono Pharmaceutical Co., Ltd.	Chemokine receptor antagonist and medical use thereof
SE0302755D0 (sv) *	2003-10-17	2003-10-17	Astrazeneca Ab	Novel compounds
US20070021498A1 (en) *	2004-10-14	2007-01-25	Nafizal Hossain	Novel tricyclic spiroderivatives as modulators of chemokine receptor activity
SE0302811D0 (sv) *	2003-10-23	2003-10-23	Astrazeneca Ab	Novel compounds
SE0303090D0 (sv) *	2003-11-20	2003-11-20	Astrazeneca Ab	Novel compounds
SE0303280D0 (sv) *	2003-12-05	2003-12-05	Astrazeneca Ab	Novel compounds
SE0303541D0 (sv) *	2003-12-22	2003-12-22	Astrazeneca Ab	New compounds
TWI350168B (en)	2004-05-07	2011-10-11	Incyte Corp	Amido compounds and their use as pharmaceuticals
EA200700117A1 (ru)	2004-06-24	2007-06-29	Инсайт Корпорейшн	N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
US20080306054A1 (en)	2005-04-13	2008-12-11	Astex Therapeutics Limited	Pharmaceutical Compounds
US8193208B2 (en)	2005-09-09	2012-06-05	Purdue Pharma L.P.	Fused and spirocycle compounds and the use thereof
JP5315590B2 (ja) *	2006-02-14	2013-10-16	Ｊｎｃ株式会社	液晶化合物、液晶組成物および液晶表示素子
US7754725B2 (en)	2006-03-01	2010-07-13	Astex Therapeutics Ltd.	Dihydroxyphenyl isoindolymethanones
TW200821316A (en)	2006-07-19	2008-05-16	Astrazeneca Ab	Novel compounds 243
WO2008044045A1 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical combinations
JP5721949B2 (ja)	2006-10-12	2015-05-20	アステックス、セラピューティックス、リミテッドＡｓｔｅｘＴｈｅｒａｐｅｕｔｉｃｓＬｉｍｉｔｅｄ	複合薬剤
JP5518478B2 (ja)	2006-10-12	2014-06-11	アステックス、セラピューティックス、リミテッド	医薬化合物
WO2008044027A2 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical compounds having hsp90 inhibitory or modulating activity
WO2008044041A1 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical combinations
GB0620259D0 (en)	2006-10-12	2006-11-22	Astex Therapeutics Ltd	Pharmaceutical compounds
WO2008083124A1 (en)	2006-12-28	2008-07-10	Rigel Pharmaceuticals, Inc.	N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
US20110124613A1 (en) *	2007-02-23	2011-05-26	Tomas Eriksson	Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma
US20110136843A1 (en) *	2007-02-23	2011-06-09	Tomas Eriksson	Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma
WO2008121066A1 (en) *	2007-03-30	2008-10-09	Astrazeneca Ab	Novel tricyclic spiropiperidines or spiropyrrolidines and their use as modulators of chemokine receptors
TW200904423A (en) *	2007-06-20	2009-02-01	Glaxo Group Ltd	Spiroindolines as modulators of chemokine receptors
WO2009011654A1 (en) *	2007-07-17	2009-01-22	Astrazeneca Ab	Process for the preparation of cyclic spiropiperidines
WO2009011655A1 (en) *	2007-07-17	2009-01-22	Astrazeneca Ab	Splropiperidine compounds, a process of their preparation, pharmaceutical compositions containing them, and their use in the treatment of airway diseases, inflammatory diseases, copd or asthma
JP5292400B2 (ja) *	2007-07-24	2013-09-18	ブリストル−マイヤーズスクイブカンパニー	ケモカイン受容体活性のモジュレーターとしてのピペリジン誘導体
JP2010536779A (ja) *	2007-08-14	2010-12-02	グラクソグループリミテッド	ケモカイン受容体のモジュレーターとしてのスピロインデンおよびスピロインダン
WO2009061881A1 (en) *	2007-11-07	2009-05-14	Glaxo Group Limited	Spirodihydrobenzofurans as modulators of chemokine receptors
EP2250176B1 (de) *	2008-01-30	2012-08-01	Cephalon, Inc.	Substituierte spirocyclische piperidinderivate als histamin-3-(h3)rezeptorliganden
FR2928150A1 (fr)	2008-02-29	2009-09-04	Vetoquinol Sa Sa	Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
GB0806527D0 (en)	2008-04-11	2008-05-14	Astex Therapeutics Ltd	Pharmaceutical compounds
EP2145891A1 (de)	2008-07-09	2010-01-20	Vetoquinol S.A.	9-substierte 5-Carboxy-Oxadiazin-Chinolon-Derivate, ihre Herstellung und ihre Anwendung als antibakterielle Mittel
AR078948A1 (es) *	2009-11-30	2011-12-14	Lilly Co Eli	Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes
US10752588B2 (en)	2014-12-19	2020-08-25	The Broad Institute, Inc.	Dopamine D2 receptor ligands
EP3233077B1 (de)	2014-12-19	2026-05-06	The Broad Institute, Inc.	Dopamin-d2-rezeptor-liganden
EP3668840A1 (de)	2017-08-15	2020-06-24	Inflazome Limited	Neuartige sulfonamid-carboxamid-verbindungen
EP4093731A1 (de)	2020-01-20	2022-11-30	Neophore Limited	An eine atp-bindungsstelle bindende isoindolinderivate
GB202008201D0 (en) *	2020-06-01	2020-07-15	Neophore Ltd	Inhibitor compounds

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4010201A (en)	1974-04-12	1977-03-01	The Upjohn Company	Organic compounds
US4166119A (en)	1978-04-14	1979-08-28	American Hoechst Corporation	Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4166120A (en) *	1978-04-14	1979-08-28	American Hoechst Corporation	Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4263317A (en)	1979-09-06	1981-04-21	Hoechst-Roussel Pharmaceuticals, Inc.	Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s
US5366986A (en)	1988-04-15	1994-11-22	T Cell Sciences, Inc.	Compounds which inhibit complement and/or suppress immune activity
DE3930262A1 (de)	1989-09-11	1991-03-21	Thomae Gmbh Dr K	Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
WO1994013696A1 (en) *	1992-12-11	1994-06-23	Merck & Co., Inc.	Spiro piperidines and homologs which promote release of growth hormone
ATE169001T1 (de) *	1993-01-28	1998-08-15	Merck & Co Inc	Substituierte spiro-azaringen als tachykinine rezeptor antagonisten
CA2187767A1 (en) *	1994-04-14	1995-10-26	Joel R. Huff	Alpha1c adrenergic receptor antagonists
US5576321A (en)	1995-01-17	1996-11-19	Eli Lilly And Company	Compounds having effects on serotonin-related systems
AU698028B2 (en)	1995-05-18	1998-10-22	Altana Pharma Ag	Phenyldihydrobenzofurans
US5931917A (en) *	1996-09-26	1999-08-03	Verifone, Inc.	System, method and article of manufacture for a gateway system architecture with system administration information accessible from a browser
US5962462A (en)	1996-12-13	1999-10-05	Merck & Co., Inc.	Spiro-substituted azacycles as modulators of chemokine receptor activity
AU5803398A (en) *	1996-12-13	1998-07-03	Merck & Co., Inc.	Spiro-substituted azacycles as modulators of chemokine receptor activity
JP2001508798A (ja) *	1997-01-21	2001-07-03	メルクエンドカンパニーインコーポレーテッド	ケモカインレセプター活性のモジュレーターとしての３，３−二置換ピペリジン類
SK11402000A3 (sk)	1998-02-04	2001-03-12	Banyu Pharmaceutical Co., Ltd	Cyklické n-acylaminoderiváty
US6151675A (en) *	1998-07-23	2000-11-21	Tumbleweed Software Corporation	Method and apparatus for effecting secure document format conversion
US6288083B1 (en) *	1998-09-04	2001-09-11	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US6212640B1 (en) *	1999-03-25	2001-04-03	Sun Microsystems, Inc.	Resources sharing on the internet via the HTTP
US6226752B1 (en) *	1999-05-11	2001-05-01	Sun Microsystems, Inc.	Method and apparatus for authenticating users
DE60005545D1 (de)	1999-10-27	2003-10-30	Millennium Pharm Inc	Pyridyl enthaltende spirocyclische verbindungen als inhibitoren der fibrinogen-abhängigen blutplättchen aggregation
WO2001064213A1 (en) *	2000-03-02	2001-09-07	Smithkline Beecham Corporation	Compounds and methods
AR028948A1 (es)	2000-06-20	2003-05-28	Astrazeneca Ab	Compuestos novedosos
US7017175B2 (en) *	2001-02-02	2006-03-21	Opentv, Inc.	Digital television application protocol for interactive television
WO2002102387A1 (en)	2001-06-18	2002-12-27	H. Lundbeck A/S	Treatment of neuropathic pain
AU2002363236A1 (en)	2001-10-30	2003-05-12	Millennium Pharmaceuticals, Inc.	Compounds, pharmaceutical compositions and methods of use therefor
SE0202133D0 (sv)	2002-07-08	2002-07-08	Astrazeneca Ab	Novel compounds
AU2003284984B2 (en)	2002-10-30	2008-10-23	Merck Sharp & Dohme Corp.	Gamma-aminoamide modulators of chemokine receptor activity
PL376925A1 (pl)	2002-11-27	2006-01-09	Incyte Corporation	Pochodne 3-aminopirolidyny jako modulatory receptorów chemokiny
AU2003298797A1 (en) *	2002-12-04	2004-06-23	Entriq Inc.	Multiple content provider user interface
US7966418B2 (en) *	2003-02-21	2011-06-21	Axeda Corporation	Establishing a virtual tunnel between two computer programs
SE0302755D0 (sv)	2003-10-17	2003-10-17	Astrazeneca Ab	Novel compounds
US20070021498A1 (en)	2004-10-14	2007-01-25	Nafizal Hossain	Novel tricyclic spiroderivatives as modulators of chemokine receptor activity
SE0302811D0 (sv)	2003-10-23	2003-10-23	Astrazeneca Ab	Novel compounds
SE0303090D0 (sv)	2003-11-20	2003-11-20	Astrazeneca Ab	Novel compounds
SE0303280D0 (sv)	2003-12-05	2003-12-05	Astrazeneca Ab	Novel compounds
SE0303541D0 (sv)	2003-12-22	2003-12-22	Astrazeneca Ab	New compounds
EP1732928A2 (de)	2004-03-29	2006-12-20	Pfizer, Inc.	Alpha-aryl- oder -heteroarylmethyl-beta-piperidinopropansäureverbindungen als orl1-rezeptorantagonisten

2002
- 2002-07-08 SE SE0202133A patent/SE0202133D0/xx unknown
2003
- 2003-07-03 TW TW092118200A patent/TW200413386A/zh unknown
- 2003-07-07 PL PL03374877A patent/PL374877A1/xx not_active Application Discontinuation
- 2003-07-07 ES ES03762957T patent/ES2298575T3/es not_active Expired - Lifetime
- 2003-07-07 DK DK03762957T patent/DK1521757T3/da active
- 2003-07-07 JP JP2004519472A patent/JP2005537255A/ja active Pending
- 2003-07-07 CN CNB038191466A patent/CN1326858C/zh not_active Expired - Fee Related
- 2003-07-07 EP EP03762957A patent/EP1521757B1/de not_active Expired - Lifetime
- 2003-07-07 CA CA002492122A patent/CA2492122A1/en not_active Abandoned
- 2003-07-07 WO PCT/SE2003/001185 patent/WO2004005295A1/en not_active Ceased
- 2003-07-07 BR BR0312560-2A patent/BR0312560A/pt not_active IP Right Cessation
- 2003-07-07 PT PT03762957T patent/PT1521757E/pt unknown
- 2003-07-07 NZ NZ537259A patent/NZ537259A/en unknown
- 2003-07-07 US US10/520,699 patent/US7449475B2/en not_active Expired - Fee Related
- 2003-07-07 CN CNA2006101435561A patent/CN1974574A/zh active Pending
- 2003-07-07 RU RU2004137278/04A patent/RU2320664C2/ru not_active IP Right Cessation
- 2003-07-07 DE DE60318948T patent/DE60318948T2/de not_active Expired - Fee Related
- 2003-07-07 AU AU2003243122A patent/AU2003243122B2/en not_active Ceased
- 2003-07-07 UA UA20041210166A patent/UA77809C2/uk unknown
- 2003-07-07 AT AT03762957T patent/ATE385235T1/de not_active IP Right Cessation
- 2003-07-07 MX MXPA05000278A patent/MXPA05000278A/es active IP Right Grant
- 2003-07-08 AR AR20030102463A patent/AR040475A1/es not_active Application Discontinuation
2005
- 2005-01-03 ZA ZA200500024A patent/ZA200500024B/xx unknown
- 2005-01-24 IS IS7662A patent/IS7662A/is unknown
- 2005-02-04 NO NO20050635A patent/NO20050635L/no not_active Application Discontinuation
2008
- 2008-04-03 CY CY20081100375T patent/CY1107915T1/el unknown
- 2008-11-05 US US12/265,251 patent/US20090062322A1/en not_active Abandoned

Also Published As

Publication number	Publication date
MXPA05000278A (es)	2005-03-31
ES2298575T3 (es)	2008-05-16
NZ537259A (en)	2006-08-31
US7449475B2 (en)	2008-11-11
ZA200500024B (en)	2006-02-22
DE60318948T2 (de)	2009-05-20
PL374877A1 (en)	2005-11-14
EP1521757B1 (de)	2008-01-30
AU2003243122A1 (en)	2004-01-23
WO2004005295A1 (en)	2004-01-15
DK1521757T3 (da)	2008-05-05
CN1675218A (zh)	2005-09-28
HK1074622A1 (en)	2005-11-18
CY1107915T1 (el)	2013-09-04
UA77809C2 (en)	2007-01-15
JP2005537255A (ja)	2005-12-08
RU2004137278A (ru)	2005-09-10
NO20050635L (no)	2005-03-31
US20050245741A1 (en)	2005-11-03
US20090062322A1 (en)	2009-03-05
AU2003243122B2 (en)	2006-09-28
IS7662A (is)	2005-01-24
RU2320664C2 (ru)	2008-03-27
CA2492122A1 (en)	2004-01-15
BR0312560A (pt)	2005-05-10
TW200413386A (en)	2004-08-01
AR040475A1 (es)	2005-04-06
DE60318948D1 (de)	2008-03-20
PT1521757E (pt)	2008-04-03
EP1521757A1 (de)	2005-04-13
SE0202133D0 (sv)	2002-07-08
CN1326858C (zh)	2007-07-18
CN1974574A (zh)	2007-06-06

Legal Events

Date

Code

Title

Description

2008-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1521757

Country of ref document: EP

2011-04-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE60318948D1 (de)	2008-03-20	Tricyclische spiropiperidine oder spiropyrrolidine
CY2014018I1 (el)	2015-12-09	Kαρβαμιδο - υποκατεστημενες πυραζολοπυριδινες
DE60313648D1 (de)	2007-06-14	Fahrwerk
DE60225119D1 (de)	2008-04-03	Verriegelbarer Wasserhahn
DK3473251T3 (da)	2024-01-22	Nikotin-cellulose-kombination
DE50303054D1 (de)	2006-05-24	Phenyl-substituierte pyrazolopyrimidine
DK1591446T3 (da)	2013-06-10	Thienopyrimidinforbindelser og anvendelse deraf.
DE60300967D1 (de)	2005-08-11	Seilantriebsanordung
DE60215683D1 (de)	2006-12-07	Uhrgehäuse
EP1494530A4 (de)	2009-06-24	Kombinationstherapie mit kleepeptiden
DE502004011106D1 (de)	2010-06-10	6-arylmethyl-substituierte pyrazolopyrimidine
DE602004003348D1 (de)	2007-01-04	Pten-hemmer oder maxi-k-kanalöffner
DE50300723D1 (de)	2005-08-11	Kettenzug
DE60236551D1 (de)	2010-07-08	Aufzugseinrichtung
NO20052356D0 (no)	2005-05-12	Redningsskoyte
FR2838029B1 (fr)	2005-12-30	Bague
FR2840053B1 (fr)	2006-11-17	Indicateur
NO20024303D0 (no)	2002-09-09	Böye
FR2851150B3 (fr)	2005-01-07	Structure de grille-pain
FI20021381L (fi)	2004-01-13	Kaivo
DE50304033D1 (de)	2006-08-10	Kettenzug
NO20025841D0 (no)	2002-12-05	Reguleringsstruktur
SE0202567D0 (sv)	2002-08-29	Spiropiperidine compounds and their use
DE112004002230D2 (de)	2006-07-27	Reise-Notfallset
SI1521757T1 (sl)	2008-06-30	Triciklični spiropiperidini ali spiropirolidini