DK3473251T3 - Nikotin-cellulose-kombination - Google Patents

Nikotin-cellulose-kombination Download PDF

Info

Publication number
DK3473251T3
DK3473251T3 DK18203402.5T DK18203402T DK3473251T3 DK 3473251 T3 DK3473251 T3 DK 3473251T3 DK 18203402 T DK18203402 T DK 18203402T DK 3473251 T3 DK3473251 T3 DK 3473251T3
Authority
DK
Denmark
Prior art keywords
nicotine
cellulose combination
cellulose
combination
Prior art date
Application number
DK18203402.5T
Other languages
English (en)
Inventor
Henri Hansson
Arne Kristensen
Original Assignee
Niconovum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32683718&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3473251(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Niconovum Ab filed Critical Niconovum Ab
Application granted granted Critical
Publication of DK3473251T3 publication Critical patent/DK3473251T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK18203402.5T 2002-12-20 2003-12-19 Nikotin-cellulose-kombination DK3473251T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200201984 2002-12-20
US51405003P 2003-10-24 2003-10-24
EP07007325.9A EP1803443B1 (en) 2002-12-20 2003-12-19 A nicotine-containing particulate material with a crystalline cellulose

Publications (1)

Publication Number Publication Date
DK3473251T3 true DK3473251T3 (da) 2024-01-22

Family

ID=32683718

Family Applications (4)

Application Number Title Priority Date Filing Date
DK03789400T DK1578422T3 (da) 2002-12-20 2003-12-19 Fysisk og kemisk stabilt nikotin-indeholdende partikelholdigt materiale
DK07007325.9T DK1803443T3 (da) 2002-12-20 2003-12-19 Nikotinholdigt partikelformigt materiale med en krystallinsk cellulose
DK18203402.5T DK3473251T3 (da) 2002-12-20 2003-12-19 Nikotin-cellulose-kombination
DK07007326.7T DK1803444T4 (da) 2002-12-20 2003-12-19 Fremgangsmåde til fremstilling af et nikotinholdigt partikulært materiale med en krystallinsk cellulose (fortrinsvis MCC)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK03789400T DK1578422T3 (da) 2002-12-20 2003-12-19 Fysisk og kemisk stabilt nikotin-indeholdende partikelholdigt materiale
DK07007325.9T DK1803443T3 (da) 2002-12-20 2003-12-19 Nikotinholdigt partikelformigt materiale med en krystallinsk cellulose

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07007326.7T DK1803444T4 (da) 2002-12-20 2003-12-19 Fremgangsmåde til fremstilling af et nikotinholdigt partikulært materiale med en krystallinsk cellulose (fortrinsvis MCC)

Country Status (19)

Country Link
US (2) US8741348B2 (da)
EP (4) EP1578422B1 (da)
JP (1) JP4708795B2 (da)
KR (1) KR20050096922A (da)
CN (1) CN1738621B (da)
AT (1) ATE359075T1 (da)
AU (1) AU2003293987B2 (da)
CA (1) CA2511185C (da)
CY (1) CY1106477T1 (da)
DE (1) DE60313216T2 (da)
DK (4) DK1578422T3 (da)
ES (4) ES2285233T3 (da)
FI (2) FI3473251T3 (da)
HU (1) HUE065285T2 (da)
NO (2) NO346973B1 (da)
NZ (1) NZ540817A (da)
PT (1) PT1578422E (da)
SI (1) SI1578422T1 (da)
WO (1) WO2004056363A2 (da)

Families Citing this family (284)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE359075T1 (de) 2002-12-20 2007-05-15 Niconovum Ab Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
SE0302947D0 (sv) * 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
CA2533577C (en) * 2003-07-24 2014-10-21 Smithkline Beecham Corporation Orally dissolving films
MXPA06002609A (es) * 2003-09-08 2006-06-05 Pfizer Health Ab Formulaciones de nicotina y uso de las mismas.
AU2004289248B2 (en) 2003-11-07 2012-05-03 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
DK1729746T3 (da) * 2004-03-19 2010-03-08 Mcneil Ab Anordning til transdermal administration af nikotin
ES2329696T3 (es) * 2004-06-29 2009-11-30 Fertin Pharma A/S Goma de mascar que libera alcaloide del tabaco.
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
DK1817014T3 (da) * 2004-11-30 2012-11-19 Fertin Pharma As Fremgangsmåde til ydelse af hurtig afhjælpning til en bruger af et nikotintyggegummi
CA2606527C (en) 2005-04-29 2013-09-10 Philip Morris Products S.A. Tobacco pouch product
US9044049B2 (en) 2005-04-29 2015-06-02 Philip Morris Usa Inc. Tobacco pouch product
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
US20160345631A1 (en) 2005-07-19 2016-12-01 James Monsees Portable devices for generating an inhalable vapor
US9675109B2 (en) 2005-07-19 2017-06-13 J. T. International Sa Method and system for vaporization of a substance
US8685478B2 (en) 2005-11-21 2014-04-01 Philip Morris Usa Inc. Flavor pouch
JP5694645B2 (ja) * 2006-03-16 2015-04-01 ニコノヴァム エービーNiconovum Ab 改善された嗅ぎたばこ組成物
WO2007104574A2 (en) * 2006-03-16 2007-09-20 Niconovum Ab Chewing gum compositions providing rapid release of nicotine
US7766019B2 (en) * 2006-07-21 2010-08-03 Gp Technologies, Inc. Porous plastic smoking cessation devices
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
PL2061889T3 (pl) * 2006-09-13 2014-11-28 22Nd Century Ltd Llc Zwiększanie poziomów alkaloidów nikotynowych
KR20090055606A (ko) * 2006-09-27 2009-06-02 니코노범 에이비 지향성 용도
JP2008120771A (ja) * 2006-11-08 2008-05-29 Bhn Kk 便秘改善剤
US7767248B2 (en) 2007-02-02 2010-08-03 Overly Iii Harry J Soft chew confectionary with high fiber and sugar content and method for making same
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
US20080210249A1 (en) * 2007-03-02 2008-09-04 Luzenberg Robert S Systems, devices and methods for delivering one or more additives to smokeless tobacco
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
WO2008121403A1 (en) * 2007-03-30 2008-10-09 Gp Technologies, Inc. Porous plastic smokeless tobacco substitutes
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
EP2322168A1 (en) * 2007-04-02 2011-05-18 Parkinson's Institute Methods and Compositions for Reduction of Side Effects of Therapeutic Treatments
GB0709162D0 (en) * 2007-05-11 2007-06-20 Jagotec Ag Dosage foam
US9888712B2 (en) 2007-06-08 2018-02-13 Philip Morris Usa Inc. Oral pouch products including a liner and tobacco beads
WO2009010881A2 (en) * 2007-07-16 2009-01-22 Philip Morris Products S.A. Oral pouch products with immobilized flavorant particles
US8202589B2 (en) * 2007-07-16 2012-06-19 Philip Morris Usa Inc. Oral delivery pouch product with coated seam
US8424541B2 (en) 2007-07-16 2013-04-23 Philip Morris Usa Inc. Tobacco-free oral flavor delivery pouch product
WO2009010876A2 (en) 2007-07-16 2009-01-22 Philip Morris Products S.A. Oral pouch product having soft edge and method of making
US8119173B2 (en) 2007-07-16 2012-02-21 Philip Morris Usa Inc. Method of flavor encapsulation through the use of a drum coater
BRPI0816890A2 (pt) * 2007-09-18 2015-03-24 Niconovum Ab Composição de goma de mascar, uso de uma combinação de nicotina-celulose, maltitol e uma base de goma, e, método para a preparação de uma composição de goma de mascar
US8991402B2 (en) 2007-12-18 2015-03-31 Pax Labs, Inc. Aerosol devices and methods for inhaling a substance and uses thereof
EP2085077A1 (en) * 2008-01-30 2009-08-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Coating compositions for controlled relaease formulations
CL2009001025A1 (es) * 2008-05-01 2010-09-24 Smithkline Beecham Corp Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco.
WO2010031552A1 (en) * 2008-09-17 2010-03-25 Niconovum Ab Process for preparing snuff composition
SI2177213T1 (sl) 2008-09-17 2013-03-29 Siegfried Ltd. Nikotin vsebujoč granulat
US8377215B2 (en) 2008-12-18 2013-02-19 Philip Morris Usa Inc. Moist botanical pouch processing
US8863755B2 (en) 2009-02-27 2014-10-21 Philip Morris Usa Inc. Controlled flavor release tobacco pouch products and methods of making
US8747562B2 (en) 2009-10-09 2014-06-10 Philip Morris Usa Inc. Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
US20110268809A1 (en) * 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
UA112974C2 (uk) * 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
SE535587C2 (sv) 2011-03-29 2012-10-02 Chill Of Sweden Ab Produkt innehållande ett fritt nikotinsalt och en ej vattenlöslig påse
EP2729148A4 (en) 2011-07-06 2015-04-22 Parkinson S Inst COMPOSITIONS AND METHOD FOR THE TREATMENT OF SYMPTOMS IN PATIENTS WITH MORBUS PARKINSON
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) * 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US20130177646A1 (en) * 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance
CN103040090B (zh) 2012-01-20 2016-03-30 奥驰亚客户服务公司 脱除烟草的口腔用产品
CN103039688B (zh) 2012-01-20 2016-01-06 奥驰亚客户服务公司 口腔用产品
CN102754907B (zh) 2012-01-20 2015-06-24 奥驰亚客户服务公司 口腔用产品
DK3098258T3 (da) 2012-01-20 2018-11-26 Altria Client Services Llc Mundprodukt
CN102754908B (zh) 2012-01-20 2015-06-10 奥驰亚客户服务公司 口腔用烟草产品
US9854831B2 (en) 2012-01-20 2018-01-02 Altria Client Services Llc Oral product
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
US9339058B2 (en) 2012-04-19 2016-05-17 R. J. Reynolds Tobacco Company Method for producing microcrystalline cellulose from tobacco and related tobacco product
US10517530B2 (en) 2012-08-28 2019-12-31 Juul Labs, Inc. Methods and devices for delivering and monitoring of tobacco, nicotine, or other substances
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
US10653180B2 (en) 2013-06-14 2020-05-19 Juul Labs, Inc. Multiple heating elements with separate vaporizable materials in an electric vaporization device
KR20240136470A (ko) 2013-05-06 2024-09-13 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법
TW201507726A (zh) * 2013-05-10 2015-03-01 Glaxosmithkline Llc 菸鹼菱形錠配製物
ES2821907T3 (es) 2013-07-11 2021-04-28 Alexza Pharmaceuticals Inc Sal de nicotina con ácido metasalicílico
WO2015009913A1 (en) 2013-07-19 2015-01-22 Altria Client Services Inc. Methods and systems for incorporating nicotine into oral products
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
US10463069B2 (en) 2013-12-05 2019-11-05 Juul Labs, Inc. Nicotine liquid formulations for aerosol devices and methods thereof
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
US9549573B2 (en) 2013-12-23 2017-01-24 Pax Labs, Inc. Vaporization device systems and methods
EP3928646B1 (en) 2013-12-23 2025-03-26 Juul Labs International Inc. Vaporization device systems
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
US9839238B2 (en) 2014-02-28 2017-12-12 Rai Strategic Holdings, Inc. Control body for an electronic smoking article
WO2015175979A1 (en) 2014-05-16 2015-11-19 Pax Labs, Inc. Systems and methods for aerosolizing a smokeable material
US20150335070A1 (en) 2014-05-20 2015-11-26 R.J. Reynolds Tobacco Company Electrically-powered aerosol delivery system
EP3871515B1 (en) 2014-05-27 2025-04-16 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US11019840B2 (en) 2014-07-02 2021-06-01 R.J. Reynolds Tobacco Company Oral pouch products
US10959456B2 (en) 2014-09-12 2021-03-30 R.J. Reynolds Tobacco Company Nonwoven pouch comprising heat sealable binder fiber
RU2709926C2 (ru) 2014-12-05 2019-12-23 Джуул Лэбз, Инк. Контроль калиброванной дозы
US20160157515A1 (en) 2014-12-05 2016-06-09 R.J. Reynolds Tobacco Company Smokeless tobacco pouch
US9968125B2 (en) 2015-01-09 2018-05-15 Philip Morris Products S.A. Nicotine—diketopiperazine microparticle formulations and methods of making the same
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
JP2018511127A (ja) 2015-03-12 2018-04-19 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 渇望入力及び支援システム
US10154689B2 (en) 2015-06-30 2018-12-18 R.J. Reynolds Tobacco Company Heat generation segment for an aerosol-generation system of a smoking article
US10869497B2 (en) 2015-09-08 2020-12-22 R.J. Reynolds Tobacco Company High-pressure cold pasteurization of tobacco material
US11224594B2 (en) 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
US20170071248A1 (en) 2015-09-16 2017-03-16 Sansa Corporation (Barbados) Inc. System and Method for Controlling the Harshness of Nicotine-Based Dry Powder Formulations
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US9585835B1 (en) 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
CA3000770A1 (en) 2015-10-07 2017-04-13 Fertin Pharma A/S Chewing gum comprising nicotine
EP3379955B1 (en) 2015-11-24 2022-05-04 R. J. Reynolds Tobacco Company Electrically-powered aerosol delivery system
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US11612183B2 (en) 2015-12-10 2023-03-28 R.J. Reynolds Tobacco Company Protein-enriched tobacco composition
SG11201806793TA (en) 2016-02-11 2018-09-27 Juul Labs Inc Fillable vaporizer cartridge and method of filling
EP3419443A4 (en) 2016-02-11 2019-11-20 Juul Labs, Inc. SAFE MOUNTING OF CARTRIDGES FOR EVAPORATOR DEVICES
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
US10329068B2 (en) 2016-05-23 2019-06-25 R.J. Reynolds Tobacco Company Flavoring mechanism for a tobacco related material
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD848057S1 (en) 2016-06-23 2019-05-07 Pax Labs, Inc. Lid for a vaporizer
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
US10617151B2 (en) 2016-07-21 2020-04-14 Rai Strategic Holdings, Inc. Aerosol delivery device with a liquid transport element comprising a porous monolith and related method
US10602775B2 (en) 2016-07-21 2020-03-31 Rai Strategic Holdings, Inc. Aerosol delivery device with a unitary reservoir and liquid transport element comprising a porous monolith and related method
US11660403B2 (en) 2016-09-22 2023-05-30 Juul Labs, Inc. Leak-resistant vaporizer device
US10080387B2 (en) 2016-09-23 2018-09-25 Rai Strategic Holdings, Inc. Aerosol delivery device with replaceable wick and heater assembly
CN110035669B (zh) 2016-12-30 2022-02-18 菲利普莫里斯生产公司 含尼古丁和纤维素的片材
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
GB201705693D0 (en) 2017-04-07 2017-05-24 Sensus Invest Ltd Carrier, apparatus and method
PL3614869T3 (pl) 2017-04-24 2025-02-10 Swedish Match North Europe Ab Aromatyzowany wilgotny doustny produkt nikotynowy w saszetce zawierający trójgliceryd
US11297876B2 (en) 2017-05-17 2022-04-12 Rai Strategic Holdings, Inc. Aerosol delivery device
SE541358C2 (en) * 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
WO2018233795A1 (en) * 2017-06-23 2018-12-27 Fertin Pharma A/S Nicotine pouch
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
EP3491940B1 (en) 2017-11-29 2024-08-07 Reemtsma Cigarettenfabriken GmbH Method of manufacturing a filling material for a pouched smokeless snus product and filling material manufactured therefrom
US10786010B2 (en) 2017-12-15 2020-09-29 Rai Strategic Holdings, Inc. Aerosol delivery device with multiple aerosol delivery pathways
CA3085204C (en) 2017-12-15 2023-01-17 Swedish Match North Europe Ab A flavoured moist oral pouched nicotine product comprising monoglyceride
US10555558B2 (en) 2017-12-29 2020-02-11 Rai Strategic Holdings, Inc. Aerosol delivery device providing flavor control
CN108323791B (zh) * 2018-01-03 2021-02-12 云南中烟工业有限责任公司 一种尼古丁-氧化锌复合物、其制备方法及包含其的烟草制品
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device
JP6371928B1 (ja) 2018-02-23 2018-08-08 株式会社 東亜産業 電子タバコ用充填物およびそれを用いた電子タバコカートリッジ
CN108391853A (zh) * 2018-03-06 2018-08-14 四川三联新材料有限公司 一种嗅烟粉及其制备方法以及在加热不燃烧烟草和卷烟中的应用
US20190307082A1 (en) 2018-04-05 2019-10-10 R.J. Reynolds Tobacco Company Oriental tobacco production methods
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
DK3807260T3 (da) 2018-06-15 2024-10-14 Reynolds Tobacco Co R Oprensning af nikotin
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
SE542990C2 (en) 2019-03-18 2020-09-22 Swedish Match North Europe Ab A packaging material and an oral pouched nicotine product
US12213510B2 (en) 2019-09-11 2025-02-04 Nicoventures Trading Limited Pouched products with enhanced flavor stability
US12342847B2 (en) 2019-09-11 2025-07-01 Nicoventures Trading Limited Oral product with cellulosic flavor stabilizer
SE1951054A1 (en) * 2019-09-18 2021-03-19 Enorama Pharma Ab Nicotine pouch
PL3833315T3 (pl) 2019-10-04 2022-12-27 Evaggelos Schjölin Produkt w saszetce nadający się do stosowania w jamie ustnej
MX2022005285A (es) 2019-10-31 2022-05-24 Nicoventures Trading Ltd Producto oral y metodo de fabricacion.
US20220400735A1 (en) 2019-11-20 2022-12-22 Swedish Match North Europe Ab An oral pouched nicotine product including a filling material comprising nicotine particles
LU101519B1 (en) * 2019-12-02 2021-06-07 Herrera Arturo Solis (S)-3-[1-MethyIpyrrolidin-2-yl]pyridine, analogues thereof, precursors thereof, or its derivatives, for the use as a pharmaceutical in form of a solid substance and a tablet
US12310959B2 (en) 2019-12-09 2025-05-27 Nicoventures Trading Limited Oral compositions with reduced water content
US20210169785A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral compositions with reduced water activity
US12550928B2 (en) 2019-12-09 2026-02-17 Nicoventures Trading Limited Liquid oral composition
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
MX2022007088A (es) 2019-12-09 2022-07-11 Nicoventures Trading Ltd Productos orales.
US20210169138A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Fibrous fleece material
US12137723B2 (en) 2019-12-09 2024-11-12 Nicoventures Trading Limited Oral products with active ingredient combinations
US12439952B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Moist oral compositions
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US12520867B2 (en) 2019-12-09 2026-01-13 Nicoventures Trading Limited Buffered oral compositions
WO2021116881A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product in a pourous pouch comprising a fleece material
US12151023B2 (en) 2019-12-09 2024-11-26 Nicoventures Trading Limited Oral composition with beet material
WO2021116842A1 (en) * 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products with controlled release
EP4072516A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Oral product comprising a cannabinoid
WO2021116865A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Agents for oral composition
US11889856B2 (en) 2019-12-09 2024-02-06 Nicoventures Trading Limited Oral foam composition
US20210169788A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral product and method of manufacture
US11883527B2 (en) 2019-12-09 2024-01-30 Nicoventures Trading Limited Oral composition and method of manufacture
US12433321B2 (en) 2019-12-09 2025-10-07 Nicoventures Trading Limited Oral composition with beet material
US20210169784A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Buffered oral compositions
CA3159813A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product with dissolvable component
WO2021116919A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Fleece for oral product with releasable component
CA3160762A1 (en) 2019-12-09 2021-06-17 Anthony Richard Gerardi Process
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
WO2021116825A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
WO2021116854A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products with active ingredient combinations
US20210169132A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition including gels
US20210169890A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with polymeric component
WO2021116824A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product comprising a cannabinoid
WO2021116855A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral compositions and methods of manufacture
US12171872B2 (en) 2019-12-09 2024-12-24 Nicoventures Trading Limited Oral compositions and methods of manufacture
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US20210169129A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Lipid-containing oral composition
WO2021116895A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Stimulus-responsive pouch
US20210169137A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Pouched products
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
WO2021116823A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
MX2022007086A (es) 2019-12-09 2022-09-09 Nicoventures Trading Ltd Agentes para la composicion oral.
US12439949B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Oral compositions with reduced water activity
PL4072347T3 (pl) 2019-12-09 2025-03-31 Nicoventures Trading Limited Włóknina do produktów doustnych z uwalnianym składnikiem
US20210169783A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral products with controlled release
US12491250B2 (en) 2019-12-09 2025-12-09 Nicoventures Trading Limited Oral composition with nanocrystalline cellulose
US20210169123A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Pouched products with enhanced flavor stability
WO2021116916A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product with multiple flavors having different release profiles
US20210169126A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with salt inclusion
JP7702400B2 (ja) 2019-12-09 2025-07-03 ニコベンチャーズ トレーディング リミテッド 経口使用のためのナノエマルジョン
WO2021116894A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Pouched products with heat sealable binder
PH12022551328A1 (en) 2019-12-09 2024-06-24 Nicoventures Trading Ltd Layered fleece for pouched product
WO2021116856A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products
CN115135175A (zh) 2019-12-19 2022-09-30 尤尔实验室有限公司 有机基尼古丁凝胶组合物
WO2021127101A1 (en) 2019-12-19 2021-06-24 Juul Labs, Inc. Metal oxide-based gel nicotine compositions
US11712059B2 (en) 2020-02-24 2023-08-01 Nicoventures Trading Limited Beaded tobacco material and related method of manufacture
SE545479C2 (en) 2020-06-03 2023-09-26 Swedish Match North Europe Ab A packaging material made of wetlaid nonwoven and a pouched product for oral use
AU2021289162A1 (en) 2020-06-08 2023-02-09 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
WO2021250516A1 (en) 2020-06-08 2021-12-16 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
GB202013489D0 (en) 2020-08-27 2020-10-14 Nicoventures Holdings Ltd Consumable
US11771132B2 (en) 2020-08-27 2023-10-03 Rai Strategic Holdings, Inc. Atomization nozzle for aerosol delivery device
GB202013491D0 (en) 2020-08-27 2020-10-14 Nicoventures Holdings Ltd Oral Product
EP4210512A1 (en) 2020-09-11 2023-07-19 Nicoventures Trading Limited Alginate-based substrates
US20220104532A1 (en) 2020-10-07 2022-04-07 NIlCOVENTURES TRADING LIMITED Methods of making tobacco-free substrates for aerosol delivery devices
CN112220756B (zh) * 2020-10-16 2023-06-13 重庆市义力医药科技有限公司 一种尼古丁颗粒组合物及其制备方法
WO2022094916A1 (zh) * 2020-11-06 2022-05-12 中国科学院深圳先进技术研究院 一种提高烟酰胺磷酸核糖转移酶活性的方法及其组合物
CN114432309A (zh) * 2020-11-06 2022-05-06 中国科学院深圳先进技术研究院 一种提高烟酰胺磷酸核糖转移酶活性的方法及其组合物
US20240008522A1 (en) 2020-11-18 2024-01-11 Nicoventures Trading Limited Oral products
US11839602B2 (en) 2020-11-25 2023-12-12 Nicoventures Trading Limited Oral cannabinoid product with lipid component
CA3204459A1 (en) 2020-12-16 2022-06-23 Liw Innovation Ab A new powder composition
EP4018849B1 (en) 2020-12-22 2024-10-23 Swedish Match North Europe AB A pouched product for oral use
EP4018848B1 (en) 2020-12-22 2024-09-18 Swedish Match North Europe AB A pouched product for oral use comprising a liquid permeable cover material and a filling material
WO2022162558A1 (en) 2021-01-28 2022-08-04 Nicoventures Trading Limited Method for sealing pouches
WO2022189977A1 (en) 2021-03-09 2022-09-15 Nicoventures Trading Limited Oral products and methods of manufacture
AU2022241149A1 (en) 2021-03-19 2023-10-19 Nicoventures Trading Limited Beaded substrates for aerosol delivery devices
WO2022195562A1 (en) 2021-03-19 2022-09-22 Nicoventures Trading Limited Extruded substrates for aerosol delivery devices
JP2024515701A (ja) 2021-04-22 2024-04-10 ニコベンチャーズ トレーディング リミテッド 発泡性口腔用組成物
WO2022224196A1 (en) 2021-04-22 2022-10-27 Nicoventures Trading Limited Orally dissolving films
EP4329522A1 (en) 2021-04-30 2024-03-06 Nicoventures Trading Limited Oral products with high-density load
US20220354155A1 (en) 2021-04-30 2022-11-10 Nicoventures Trading Limited Multi-compartment oral pouched product
EP4094593A1 (en) 2021-05-28 2022-11-30 Swedish Match North Europe AB A flavoured moist oral pouched nicotine product comprising ethyl cellulose
JP2024523362A (ja) 2021-06-16 2024-06-28 ニコベンチャーズ トレーディング リミテッド 溶解可能な組成物を含むパウチ製品
WO2022269475A1 (en) 2021-06-21 2022-12-29 Nicoventures Trading Limited Oral product tablet and method of manufacture
CA3223902A1 (en) 2021-06-25 2022-12-29 Richard Svensson Oral products and method of manufacture
WO2023281469A1 (en) 2021-07-09 2023-01-12 Nicoventures Trading Limited Extruded structures
AU2022313549A1 (en) 2021-07-22 2024-01-18 Nicoventures Trading Limited Methods of preparing compositions comprising a constituent, derivative or extract of cannabis
IL309993A (en) 2021-07-22 2024-03-01 Nicoventures Trading Ltd A component, derivative or extract of cannabis in amorphous form
JP2024528847A (ja) 2021-07-22 2024-08-01 ニコベンチャーズ トレーディング リミテッド カンナビノイド及び/又はカンナビノイド類似体を含むナノエマルジョン
JP2024530872A (ja) 2021-07-22 2024-08-27 ニコベンチャーズ トレーディング リミテッド カンナビスの成分、誘導体又は抽出物を含む組成物
CA3224601A1 (en) 2021-07-22 2023-01-26 Steven Alderman Constituent, derivative or extract of cannabis in a water soluble matrix
MX2024001092A (es) 2021-07-22 2024-05-15 Nicoventures Trading Ltd Composiciones que comprenden un constituyente, derivado o extracto de cannabis.
EP4373300A1 (en) 2021-07-22 2024-05-29 Nicoventures Trading Limited Composition comprising a constituent, derivative or extract of cannabis
JP2024526812A (ja) 2021-07-22 2024-07-19 ニコベンチャーズ トレーディング リミテッド カンナビスの成分、誘導体又は抽出物を含む組成物
WO2023002194A1 (en) 2021-07-22 2023-01-26 Nicoventures Trading Limited Compositions comprising constituents, derivatives or extracts of cannabis
EP4376642A1 (en) 2021-07-30 2024-06-05 Nicoventures Trading Limited Aerosol generating substrate comprising microcrystalline cellulose
US20230098503A1 (en) 2021-09-30 2023-03-30 Nicoventures Trading Limited Oral gum composition
MX2024003998A (es) 2021-09-30 2024-06-03 Nicoventures Trading Ltd Producto oral con una amina basica y un agente de emparejamiento ionico.
US20230148660A1 (en) 2021-11-15 2023-05-18 Nicoventures Trading Limited Products with enhanced sensory characteristics
CA3238151A1 (en) * 2021-11-15 2023-05-19 Shahin ROOHINEJAD Oral products with nicotine-polymer complex
CN114304712A (zh) * 2021-12-17 2022-04-12 深圳市元雾科技有限公司 一种液体高负载的尼古丁口含制品颗粒及其制备方法
CA3241938A1 (en) 2021-12-20 2023-06-29 Bridget CRUMP Substrate material comprising beads for aerosol delivery devices
CN114304711A (zh) * 2021-12-20 2022-04-12 深圳市元雾科技有限公司 一种pH稳定的尼古丁口含制品
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product
CN114521669A (zh) * 2022-02-25 2022-05-24 深圳市元雾科技有限公司 一种尼古丁稳定的口含烟制品及其制备方法
US20230309603A1 (en) 2022-03-31 2023-10-05 R.J. Reynolds Tobacco Company Agglomerated botanical material for oral products
CA3247270A1 (en) 2022-04-06 2023-10-12 Nicoventures Trading Limited PRODUCTS IN BAGS WITH HEAT-SEALABLE BINDER
WO2024069544A1 (en) 2022-09-30 2024-04-04 Nicoventures Trading Limited Reconstituted tobacco substrate for aerosol delivery device
JP2025534346A (ja) 2022-09-30 2025-10-15 アール・ジエイ・レイノルズ・タバコ・カンパニー 再構成されたタバコの形成方法
EP4601490A1 (en) 2022-10-14 2025-08-20 Nicoventures Trading Limited Capsule-containing pouched products
EP4608181A1 (en) 2022-10-24 2025-09-03 Nicoventures Trading Limited Shaped pouched products
WO2024095164A1 (en) 2022-11-01 2024-05-10 Nicoventures Trading Limited Products with spherical filler
EP4665172A1 (en) 2023-02-15 2025-12-24 Nicoventures Trading Limited Oral products with high-density load
WO2024180481A1 (en) 2023-02-28 2024-09-06 Nicoventures Trading Limited Caffeine-containing oral product
WO2024201346A1 (en) 2023-03-31 2024-10-03 Nicoventures Trading Limited Functionalized fleece material production
EP4687502A1 (en) 2023-03-31 2026-02-11 Nicoventures Trading Limited Starchless molding process for oral products
GB202306392D0 (en) 2023-04-28 2023-06-14 Nicoventures Trading Ltd Aerosol generating material
WO2025062340A1 (en) 2023-09-22 2025-03-27 R. J. Reynolds Tobacco Company Nicotine extraction from plastic packaging materials
WO2025068817A1 (en) 2023-09-29 2025-04-03 R. J. Reynolds Tobacco Company Apparatus and system for recovering material from oral wrapped products and related method
GB202319621D0 (en) 2023-12-20 2024-01-31 Nicoventures Trading Ltd Oral product comprising porous sponge
GB202319627D0 (en) 2023-12-20 2024-01-31 Nicoventures Trading Ltd Diffusion-modifying pouch for oral products
EP4585055A1 (en) 2024-01-12 2025-07-16 Nicoventures Trading Limited Oral product with probiotic component
EP4585059A1 (en) 2024-01-12 2025-07-16 Nicoventures Trading Limited Effervescent pouched product
EP4595781A1 (en) 2024-01-31 2025-08-06 Nicoventures Trading Limited Pouched products containing shreddable filler
EP4599698A1 (en) 2024-02-07 2025-08-13 Nicoventures Trading Limited Products comprising sensory agents
EP4602929A1 (en) 2024-02-19 2025-08-20 Nicoventures Trading Limited Oral product with powder coating
WO2025189277A1 (en) * 2024-03-12 2025-09-18 Tjp Labs Inc. Nicotine containing composition
EP4620318A1 (en) 2024-03-21 2025-09-24 Nicoventures Trading Limited Pouched product with humectant
EP4623708A1 (en) 2024-03-26 2025-10-01 Nicoventures Trading Limited Sweetener composition for pouched oral products
WO2025213000A1 (en) * 2024-04-05 2025-10-09 ODS Products, LLC Pouches comprising active ingredients
EP4640075A1 (en) 2024-04-22 2025-10-29 Nicoventures Trading Limited Oral pouched product with self-emulsifying delivery system
EP4640072A1 (en) 2024-04-24 2025-10-29 Nicoventures Trading Limited Fleece materials treated with an ion-pairing agent and oral products comprising fleece materials treated with an ion-pairing agent
EP4643664A1 (en) 2024-05-03 2025-11-05 Nicoventures Trading Limited Oral product with plant-based filler component
EP4643666A1 (en) 2024-05-03 2025-11-05 Nicoventures Trading Limited Oral product with plant-based filler component
EP4643665A1 (en) 2024-05-03 2025-11-05 Nicoventures Trading Limited Oral product with plant-based filler component
EP4659594A1 (en) 2024-06-06 2025-12-10 Nicoventures Trading Limited Oral products containing modified nicotine-polymer complex
EP4659595A1 (en) 2024-06-06 2025-12-10 Nicoventures Trading Limited Nicotine-polymer complex comprising multiple nicotine forms
EP4659596A1 (en) 2024-06-06 2025-12-10 Nicoventures Trading Limited Oral products with low free-base nicotine content
EP4678009A1 (en) 2024-07-08 2026-01-14 Nicoventures Trading Limited Premix containing gelling agent for oral product

Family Cites Families (276)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US865026A (en) 1906-12-15 1907-09-03 Ellis Foster Co Masticable tobacco preparation.
US940521A (en) * 1909-05-06 1909-11-16 George A Endicott Wire-stretching appliance.
US3877468A (en) * 1970-07-22 1975-04-15 Leo Ab Chewable tobacco substitute composition
US3901248A (en) 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3777029A (en) * 1971-01-28 1973-12-04 Hoffmann La Roche Chewable multivitamin tablets contain-ing aluminum nicotinate
CH542002A (it) 1971-07-27 1973-09-30 Coster Tecnologie Speciali Spa Contenitore di aerosol su cui è applicato un cappuccio erogatore munito di cannula oscillabile
US3845217A (en) 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
JPS5350515Y2 (da) 1975-02-28 1978-12-04
DE2526702A1 (de) 1975-06-14 1976-12-23 Volkswagenwerk Ag Spruehduese, insbesondere zur hohlraumkonservierung
GB1528391A (en) 1976-01-05 1978-10-11 Gildemeister V Aerosol compositions
JPS52114010A (en) 1976-03-22 1977-09-24 Ozawa Miyo Medicine for nicotinism
GB2030862A (en) 1978-04-10 1980-04-16 Smith A A composition for treating drug addiction such as smoking nicotine-containing products
FR2467604A1 (fr) 1979-10-22 1981-04-30 Mercier Jean Embout adapte pour pulverisation nasale physiologique
US4317837A (en) * 1980-11-25 1982-03-02 Life Savers, Inc. Tobacco-flavored chewing gum
JPS59500217A (ja) * 1982-02-22 1984-02-16 ベロルススキ− ナウチノ− イスレドワ−チエルスキ− サニタルノ− ギギエニチエスキ− インスチツ−ト 抗ニコチン効果を有する製剤およびその製造法
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
DE3241437A1 (de) 1982-11-10 1984-05-10 Ferdinand Prof. Dr.med. 6901 Wilhelmsfeld Schmidt Mittel zum zwecke der raucherentwoehnung und/oder fuer nebenwirkungsfreien nikotingenuss bei suchtrauchern
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
SU1232260A1 (ru) 1983-02-01 1986-05-23 Mamchur Fedor Способ получени вещества,обладающего антиникотиновой активностью
GB8317576D0 (en) 1983-06-29 1983-08-03 Shaw A S W Consumer tobacco products
US4593572A (en) * 1983-10-03 1986-06-10 Universal Thread Grinding Company Lubricated drive mechanism
US4655231A (en) * 1984-01-09 1987-04-07 Advanced Tobacco Products, Inc. Snuff and preparation thereof
SU1268141A1 (ru) 1984-03-26 1986-11-07 Научно-Производственное Объединение Министерства Пищевой Промышленности Армсср Способ получени антиникотиновой жевательной резинки
DE3429389C1 (de) * 1984-08-09 1986-03-13 Brugger, Inge, geb. Ritzau, 8130 Starnberg Inhalator
JPS61251619A (ja) * 1985-04-30 1986-11-08 Nitto Electric Ind Co Ltd ニコチン含有テ−プ製剤
US4800903A (en) 1985-05-24 1989-01-31 Ray Jon P Nicotine dispenser with polymeric reservoir of nicotine
EP0205133A1 (de) 1985-06-14 1986-12-17 Marie Luise Dr. Schicht Plastische Kaumasse auf Basis einer Kaugummigrundmasse
US4696315A (en) 1985-09-19 1987-09-29 Better Life International, Inc. Herbal snuff composition
US4817640A (en) 1985-09-19 1989-04-04 Better Life International Life, Inc. Herbal chew and snuff compositions
JP2543683B2 (ja) 1985-12-13 1996-10-16 武田薬品工業株式会社 綜合ビタミン糖衣錠
US5198226A (en) 1986-01-30 1993-03-30 Syntex (U.S.A.) Inc. Long acting nicardipine hydrochloride formulation
GB8614805D0 (en) * 1986-06-18 1986-07-23 British American Tobacco Co Aerosol device
GB8615676D0 (en) 1986-06-26 1986-07-30 Stoppers Co Ltd Nicotine containing lozenge
DE3639418A1 (de) 1986-11-18 1988-06-09 Forschungsgesellschaft Rauchen Nikotinhaltiges mittel
FR2608156B1 (fr) * 1986-12-12 1988-12-30 Ethypharm Sa Chewing-gum pour se liberer du tabac
US4835162A (en) * 1987-02-12 1989-05-30 Abood Leo G Agonists and antagonists to nicotine as smoking deterents
US4943435A (en) 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
US4933188B1 (en) 1987-12-31 1997-07-15 Warner Lambert Co Chewing gum composition with improved physical stability
JPH01243945A (ja) 1988-03-25 1989-09-28 Lotte Co Ltd 嫌煙ガム
JPH0272118A (ja) 1988-09-08 1990-03-12 Kitsuen Kagaku Kenkyu Zaidan 冠血管拡張剤
GB8828468D0 (en) * 1988-12-06 1989-01-05 Stoppers Co Ltd Nicotine containing lozenge
IE62662B1 (en) * 1989-01-06 1995-02-22 Elan Corp Plc Use of nicotine in the treatment of conditions susceptible to said treatment
US5154927A (en) 1989-01-19 1992-10-13 Wm. Wrigley Jr. Company Gum composition containing dispersed porous beads containing active chewing gum ingredients and method
DK365389D0 (da) 1989-07-24 1989-07-24 Fertin Lab As Antifungalt tyggegummipraeparat
NO168921C (no) * 1989-07-31 1992-04-22 Svein Knudsen Roekfri sigaretterstatning til bruk ved roekavvenning ellertil bruk i roekfrie miljoeer
ES2097155T3 (es) 1989-10-02 1997-04-01 Cima Labs Inc Forma de dosificacion efervescente y metodo de administracion.
US4967733A (en) * 1989-10-16 1990-11-06 Rousseau Yvon J Lifting carriage
US5525351A (en) * 1989-11-07 1996-06-11 Dam; Anders Nicotine containing stimulant unit
DK615689A (da) 1989-11-07 1991-05-08 Anders Dam Rygesupplement eller rygeerstatningsprodukt
JP2914690B2 (ja) * 1989-12-13 1999-07-05 グレラン製薬株式会社 安定なビタミンd▲下3▼類含有製剤
SE8904295D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Smoking substitute
US5077104A (en) * 1989-12-21 1991-12-31 Alza Corporation Nicotine packaging materials
US5512306A (en) * 1992-06-19 1996-04-30 Pharmica Ab Smoking substitute
JPH03209327A (ja) * 1990-01-11 1991-09-12 Teikoku Seiyaku Kk ニコチン含有口腔粘膜貼付剤
JPH03209326A (ja) * 1990-01-11 1991-09-12 Teikoku Seiyaku Kk ニコチン含有口腔粘膜貼付剤
US4996315A (en) * 1990-01-16 1991-02-26 Texaco Chemical Company Novel synthesis of cyclic compounds
US5167242A (en) * 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
FI913526L (fi) 1990-08-23 1992-02-24 Wrigley W M Jun Co Tuggummi med laog fukthalt.
US5488962A (en) * 1990-10-10 1996-02-06 Perfetti, S.P.A. Chewing gum which is a substitute for tobacco smoke
JP2580456B2 (ja) * 1991-02-21 1997-02-12 ジェネンコア インターナショナル インコーポレーテッド 結晶質セルロースの製造
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
GB9111224D0 (en) 1991-05-24 1991-07-17 Charwell Consumer Prod Smoking substitute preparation
RU2029474C1 (ru) 1991-06-28 1995-02-27 Тетюшева Светлана Игоревна Жевательная резинка
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
GB9200047D0 (en) 1992-01-03 1992-02-26 Univ Alberta Nicotine-containing nasal spray
DK0557129T3 (da) 1992-02-20 1997-04-14 Wielligh Johannes Louw Kot Von Produkt til at hjælpe rygere med at holde op med at ryge
US5654003A (en) * 1992-03-05 1997-08-05 Fuisz Technologies Ltd. Process and apparatus for making tablets and tablets made therefrom
FR2688400B1 (fr) 1992-03-11 1999-06-25 Gilles Gagnot Dispositif pour le lavage de poches parodontales d'un patient.
CA2095776C (en) * 1992-05-12 2007-07-10 Richard C. Fuisz Rapidly dispersable compositions containing polydextrose
FR2698268B1 (fr) 1992-11-24 1995-01-20 Oreal Composition photoprotectrice administrée par voie orale.
CN1034551C (zh) 1993-01-01 1997-04-16 丘波岭 烟酸和/或烟酸衍生物在制备戒烟用组合物中的应用
DE4301782C1 (de) * 1993-01-23 1994-08-25 Lohmann Therapie Syst Lts Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit
US5573774A (en) * 1993-02-02 1996-11-12 Keenan; Robert M. Nicotine metabolites, nicotine dependence and human body weight
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US5318523A (en) * 1993-07-13 1994-06-07 Lu Jieh Shan Drug-feeder for children
US5549906A (en) 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
CN1089834A (zh) 1993-10-14 1994-07-27 王子芸 戒烟口胶的配方及加工工艺
SE9303574D0 (sv) 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
SE502268C2 (sv) 1994-01-26 1995-09-25 Aga Ab Sätt, användning och beredning av aerosol för läkemedelsdistribution innehållande helium och/eller neon
GB2289204B (en) 1994-04-21 1998-01-14 Williamson Research Limited A chewing gum for use as a nicotine substitute and slimming aid
AU2703795A (en) * 1994-06-23 1996-01-19 Procter & Gamble Company, The Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine
IT1274034B (it) 1994-07-26 1997-07-14 Applied Pharma Res Composizioni farmaceutiche a base di gomma da masticare e procedimento per la loro preparazione
US5507278A (en) * 1994-11-18 1996-04-16 Karell; Manuel L. Tongue-guard for inhaler
US5810018A (en) * 1994-12-29 1998-09-22 Monte; Woodrow C. Method, composition and apparatus for reducing the incidence of cigarette smoking
DK0801559T3 (da) * 1995-02-08 2002-06-17 Yamanouchi Europ Bv Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum
DK0745380T3 (da) 1995-05-11 2005-12-05 Univ Utah Res Found Tobakserstatning
WO1997002273A1 (en) 1995-07-05 1997-01-23 The Procter & Gamble Company Warming compounds
SE9503154D0 (sv) 1995-09-13 1995-09-13 Pharmacia Ab Method for marking objects and objects being marked with such method
US6506425B2 (en) * 1995-09-13 2003-01-14 Pharmacia Ab Packaged markable ingestible compressible object
US5875774A (en) 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
US5692493A (en) * 1996-03-08 1997-12-02 Diemolding Corporation Tongue Protector
US5955098A (en) 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
EP0893992B1 (en) 1996-04-16 2004-03-03 Novartis Consumer Health S.A. Fast disintegrating oral dosage form
CA2178021C (en) * 1996-04-19 1999-09-28 Theodore H. Stanley Tobacco substitute
PT906089E (pt) * 1996-05-13 2004-01-30 Novartis Consumer Health Sa Sistema de administracao bucal
TW506836B (en) * 1996-06-14 2002-10-21 Janssen Pharmaceutica Nv Fast-dissolving galanthamine hydrobromide tablet
ATE291930T1 (de) 1996-07-12 2005-04-15 Daiichi Seiyaku Co Schnell zerfallende, druckgeformte materialien sowie prozess zu deren herstellung
US5667838A (en) 1996-09-05 1997-09-16 The Procter & Gamble Company Separately milling nut solids and particulate water soluble solids to reduce stickiness and improve flavor intensity of nut spreads
DE19639343C2 (de) 1996-09-25 1998-10-08 Suedzucker Ag Komprimate, enthaltend ein Süßungsmittelgemisch
GB2318737B (en) 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
JPH10287561A (ja) * 1997-04-11 1998-10-27 Taisho Pharmaceut Co Ltd イブプロフェン配合固形製剤及びその製造方法
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
CN1089834C (zh) 1997-06-27 2002-08-28 南京英达机械制造有限公司 沥青路面加热再生修补设备
SE9703458D0 (sv) 1997-09-25 1997-09-25 Pharmacia & Upjohn Ab Nicotine compositions and methods of formulation thereof
US6908631B1 (en) * 1997-12-01 2005-06-21 Nicogen, Inc. Therapeutic and diagnostic methods dependent on CYP2A enzymes
AU2091799A (en) * 1997-12-31 1999-07-19 University Of Utah Research Foundation Uses of alpha-conotoxin peptides
DE29800300U1 (de) 1998-01-09 1998-04-23 Wieninger, Dieter, Dr., 94036 Passau Nikotin und dessen Derivate in Kombination mit einem Antitussivum
JP2002511414A (ja) 1998-04-09 2002-04-16 ファルマシア・アンド・アップジョン・カンパニー 神経疾患のための新しい治療
US6211194B1 (en) * 1998-04-30 2001-04-03 Duke University Solution containing nicotine
US6190696B1 (en) 1998-06-08 2001-02-20 Pieter J. Groenewoud Stabilized thyroxine medications
AU4514299A (en) 1998-06-15 2000-01-05 Karl Holm Inhalation device
US6476078B2 (en) * 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US20020098264A1 (en) 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
US6344222B1 (en) * 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
US5997905A (en) * 1998-09-04 1999-12-07 Mcneil-Ppc Preparation of pharmaceutically active particles
AU6412299A (en) 1998-10-08 2000-04-26 Biovail Technologies Limited Composition and method for medicated chewing gum delivery system
JP2000128776A (ja) * 1998-10-19 2000-05-09 Asahi Chem Ind Co Ltd フィルムコーティング顆粒およびその製造方法
MY125803A (en) 1998-11-06 2006-08-30 Fuji Chem Ind Co Ltd A tocotrienol-containing powder, a process for preparing it and a tablet comprising compressed said powder into a tablet form
US6232082B1 (en) * 1998-12-01 2001-05-15 Nabi Hapten-carrier conjugates for treating and preventing nicotine addiction
US6551634B2 (en) 1998-12-09 2003-04-22 Hans Boerge Joergensen Method for production of chewing or bubble gum pieces
US7163705B2 (en) 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
CA2355777A1 (en) * 1998-12-15 2000-06-22 Wm. Wrigley Jr. Company Controlling release of active agents from a chewing gum coating
US6586023B1 (en) 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US6734215B2 (en) * 1998-12-16 2004-05-11 University Of South Florida Exo-S-mecamylamine formulation and use in treatment
DE69939498D1 (de) 1998-12-16 2008-10-16 Univ South Florida Exo-S-Mecamylamin-Formulierung
OA11740A (en) 1998-12-24 2005-05-13 Janssen Pharmaceutica Nv Controlled release galantamine composition.
US6855820B2 (en) * 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
SE9900215D0 (sv) 1999-01-26 1999-01-26 Pharmacia & Upjohn Ab New use
FR2788982B1 (fr) * 1999-02-02 2002-08-02 Synthelabo Compositions pharmaceutiques contenant de la nicotine et leur application dans le sevrage tabagique
RO121628B1 (ro) 1999-02-05 2008-01-30 Cipla Limited Compoziţie medicinală, topică, pulverizabilă,dozator care o conţine, procedeu de realizare a dozatorului şi utilizarea compoziţiei menţionate
US6982089B2 (en) 1999-02-24 2006-01-03 Tact Ip, Llc Cytokine antagonists for neurological and neuropsychiatric disorders
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
ATE451912T1 (de) 1999-03-22 2010-01-15 Pf Medicament Arzneistoffhaltiger kaugummi, dessen herstellungsverfahren und so erhaltene tablette
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6426090B1 (en) 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US20010016593A1 (en) * 1999-04-14 2001-08-23 Wilhelmsen Paul C. Element giving rapid release of nicotine for transmucosal administration
FR2792200B3 (fr) 1999-04-16 2001-06-08 Unicliffe Ltd Substitut du tabac sous forme d'un comprime ou d'une pastille a sucer
JP4249847B2 (ja) * 1999-05-31 2009-04-08 エーザイ・アール・アンド・ディー・マネジメント株式会社 ビタミンkを含有する口腔内崩壊型錠剤
US6799576B2 (en) 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
US20080138399A1 (en) 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US20080138398A1 (en) 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US8256433B2 (en) 1999-07-16 2012-09-04 Aradigm Corporation Systems and methods for effecting cessation of tobacco use
DE19943491B4 (de) 1999-09-10 2010-04-01 Südzucker AG Mannheim/Ochsenfurt Verbesserte Komprimate
US6322828B1 (en) 1999-09-13 2001-11-27 Deseret Laboratories, Inc. Process for manufacturing a pharmaceutical chewing gum
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
EP1231900A1 (en) 1999-11-23 2002-08-21 The Robert Gordon University Bilayered buccal tablets comprising nicotine
GB0004708D0 (en) 2000-02-28 2000-04-19 Britannia Pharmaceuticals Ltd Restricting reinstatement of drug use
DE10013712A1 (de) * 2000-03-20 2001-09-27 Nutrinova Gmbh Nikotinsalze mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung
US20010036943A1 (en) 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
US6607752B2 (en) * 2000-07-27 2003-08-19 Rohm And Haas Company Method for the anhydrous loading of nicotine onto ion exchange resins
MXPA03001472A (es) * 2000-08-16 2003-06-06 Upjohn Co Compuestos para el tratamiento de trastornos adictivos.
DE10044545A1 (de) 2000-09-05 2002-04-04 Roland Bodmeier Retardpartikeldispersion
CN100506060C (zh) 2001-03-23 2009-07-01 古木林科有限公司 口香糖的一步制造方法
US6861434B2 (en) * 2001-04-26 2005-03-01 Wyeth Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one
US6872405B2 (en) 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
KR20010078976A (ko) 2001-05-28 2001-08-22 전창호 껌의 조성물
SE0102197D0 (sv) 2001-06-20 2001-06-20 Pharmacia Ab New product and use and manufacture thereof
US6602518B2 (en) 2001-06-28 2003-08-05 Wm. Wrigley Jr. Company Chewable product including active ingredient
US6849624B2 (en) 2001-07-31 2005-02-01 Hoffmann-La Roche Inc. Aromatic and heteroaromatic substituted amides
JP2005510339A (ja) 2001-08-08 2005-04-21 ザ プロクター アンド ギャンブル カンパニー ドープされた高活性の吸着材料
US7208186B2 (en) 2001-09-18 2007-04-24 Spi Pharma, Inc. Chewing gum formulation and method of making the same
HU227543B1 (en) * 2001-09-28 2011-08-29 Richter Gedeon Nyrt N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them
ATE276676T1 (de) * 2001-10-22 2004-10-15 Ivo Pera Zusammensetzung zur reduzierung oder entwöhnung von nikotinabhängigkeit
US20030082109A1 (en) * 2001-10-30 2003-05-01 Leonard Gorenstein Dextrorotary nicotine for smoking cessation
US20040037879A1 (en) * 2001-11-02 2004-02-26 Adusumilli Prasad S. Oral controlled release forms useful for reducing or preventing nicotine cravings
US6599901B1 (en) 2001-11-19 2003-07-29 Hoffman-La Roche Inc. Pyridone substituted benzothiazole derivatives
FR2832311B1 (fr) * 2001-11-21 2004-04-16 Besins Int Belgique Poudre filmogene, compositions la comprenant, leurs procedes de preparation et leurs utilisations
US20060057207A1 (en) * 2001-11-30 2006-03-16 Pfizer Inc Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
IL161857A0 (en) 2001-11-30 2005-11-20 Pfizer Prod Inc Pharmaceutical compositions of 5,7,14-triazatetracycloÄ10.3.1.0(2,11).0(4,9)Ü-hexadeca-2(11)3,5,7,9-pentaene
BR0214578A (pt) * 2001-11-30 2004-11-03 Pfizer Prod Inc Compostos azopolicìclicos fundidos com arila
DE60224832T2 (de) 2001-12-21 2009-01-22 Galenica Ab Tabak und/oder tabak in kombination mit tabakersatz zusammensetzung zur verwendung als schnupf in der mundhöhle
DE10163667B4 (de) * 2001-12-21 2006-10-26 Hf Arzneimittelforschung Gmbh Verwendung von Desoxypeganin zur Behandlung der klinischen Depression
SE0104388D0 (sv) 2001-12-27 2001-12-27 Pharmacia Ab New formulation and use and manufacture thereof
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
KR100352030B1 (en) * 2002-01-10 2002-09-11 Orion Corp Gum composition for removing nicotine
US20040102440A1 (en) 2002-07-01 2004-05-27 Wong Erik Ho Fong Method of promoting smoking cessation
WO2003061399A1 (en) 2002-01-25 2003-07-31 De Abhijit Chewing gum composition and a process for preparing the same
WO2003082329A2 (en) * 2002-03-01 2003-10-09 The Board Of Regents Of The University Of Nebraska Compositions and compounds for use as molecular adjuvant for a nicotine vaccine
US20030171408A1 (en) 2002-03-11 2003-09-11 Caplan Jay L. Therapeutic method of delivering a medicament to avoid irritating effects on membranes of user
SE0200895D0 (sv) 2002-03-22 2002-03-22 Astrazeneca Ab New pharmaceutical composition
US6797707B2 (en) * 2002-03-29 2004-09-28 University Of Florida Antagonists of RF-amide neuropeptides
EP1350434A1 (en) 2002-04-05 2003-10-08 Gum Base Co. S.p.A. Chewing gum in powder form and method of preparation
CN1383814A (zh) 2002-05-28 2002-12-11 沈阳东宇工业技术研究院有限公司 口腔速崩片及制备方法
US6586449B1 (en) * 2002-05-28 2003-07-01 Cambrex Charles City, Inc. Nicotine-containing, controlled release composition and method
SE0201669D0 (sv) 2002-06-03 2002-06-03 Pharmacia Ab New formulation and use thereof
ITMI20021392A1 (it) 2002-06-25 2003-12-29 Nicox Sa Forme farmaceutiche per la somministrazione orale di farmaci liquidi a temperatura ambiente dotate di migliore biodisponibilita'
US20040002520A1 (en) 2002-07-01 2004-01-01 Soderlund Patrick L. Composition and method for cessation of Nicotine cravings
EP1523241B1 (en) 2002-07-02 2008-07-02 Gumlink A/S Compressed resin moderated chewing gum
CN100367869C (zh) 2002-07-02 2008-02-13 古木林科有限公司 压缩口香糖
KR100992521B1 (ko) 2002-07-02 2010-11-05 굼링크 에이/에스 츄잉 검 압축 정제 ii
US20050197343A1 (en) 2002-07-04 2005-09-08 Peter Gmeiner Utilization of heteroarene carboxamide as dopamine-d3 ligands for the treatment of cns diseases
US20040013752A1 (en) * 2002-07-05 2004-01-22 Wolfson Philip E. Buccal and sublingual mucosally absorbed herbal compositions for relieving nicotine withdrawal symptoms and craving for nicotine and nicotine containing substances
NZ537003A (en) * 2002-07-18 2008-03-28 Cytos Biotechnology Ag Hapten-carrier conjugates comprising virus like particles and uses thereof
EP1551393A4 (en) 2002-07-30 2010-06-16 Peter Migaly COMBINATION OF THERAPY FOR DEPRESSION, PREVENTION OF SUICIDE AND VARIOUS MEDICAL AND PSYCHIATRIC DISORDERS
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
SE0202430D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202465D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
US8354447B2 (en) 2002-09-10 2013-01-15 The Scripps Research Institute mGLU receptors antagonists for treating disorders associated with mGLU receptors including addiction and depression
US7345092B2 (en) * 2002-09-12 2008-03-18 Summit Vetpharm, Llc High concentration topical insecticides containing pyrethroids
GB2393392A (en) 2002-09-17 2004-03-31 Abhijit De Betel nut and nicotine chewing gum
DE60234884D1 (de) 2002-09-24 2010-02-04 Gumlink As Kaugummi mit niedrigem Feuchtigkeitsgehalt
CN100471398C (zh) 2002-09-24 2009-03-25 古木林科有限公司 包括至少两种不同的生物可降解聚合物的口香糖
RU2303365C2 (ru) 2002-09-24 2007-07-27 Гумлинк А/С Жевательная резинка с улучшенным высвобождением ингредиентов жевательной резинки
ES2311631T3 (es) 2002-09-24 2009-02-16 Gumlink A/S Goma de mascar biodegradable que comprende por lo menos un polimero biodegradable de alto peso molecular.
ES2280835T3 (es) * 2002-12-19 2007-09-16 Pharmacia Corporation Formulacion no higroscopica que comprende un farmaco higroscopico.
EP1575384B1 (en) 2002-12-19 2011-06-15 Swedish Match North Europe AB A non-chewable tobacco composition
ATE359075T1 (de) * 2002-12-20 2007-05-15 Niconovum Ab Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
CN1511550A (zh) 2002-12-27 2004-07-14 袁冀平 一种降低烟碱的药物制剂及应用
US7361667B2 (en) 2003-01-09 2008-04-22 P2D, Inc. 4′,4″-substituted 3α-(diphenylmethoxy) tropane analogs for treatment of mental disorders
SE0302947D0 (sv) 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
EA012306B1 (ru) 2003-01-24 2009-08-28 Магле Холдинг Аб Композиционный материал для доставки через слизистые оболочки
US20060147580A1 (en) 2003-02-04 2006-07-06 Vibeke Nissen Compressed chewing gum tablet
US20040151771A1 (en) 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
RU2342846C2 (ru) 2003-02-04 2009-01-10 Гумлинк А/С Таблетка прессованной жевательной резинки и способ ее производства
EP1449525A1 (en) 2003-02-20 2004-08-25 Cross Chem Llc chewing gum in the form of multi-layer tablets
KR101170844B1 (ko) 2003-02-24 2012-08-02 파마슈티칼 프로덕션스, 인크. 경점막 약물 전달 시스템
US20040224963A1 (en) 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
MXPA05012507A (es) 2003-05-20 2006-01-30 Pfizer Prod Inc Composiciones farmaceuticas de vareniclina.
WO2005040338A2 (en) 2003-05-21 2005-05-06 The Scripps Research Institute Constrained alkaloid immunogens and antibodies and uses thereof
JP2005025135A (ja) * 2003-07-04 2005-01-27 Showa Electric Wire & Cable Co Ltd 高信頼性光導波路型デバイス
WO2005007655A1 (en) 2003-07-21 2005-01-27 Pfizer Products Inc. Nicotine addiction reducing heteroaryl fused azapolycyclic compounds
US20050058609A1 (en) * 2003-07-22 2005-03-17 Alireza Nazeri Medicated toothpick
US20050034738A1 (en) 2003-08-11 2005-02-17 Whalen William F. Chewing tobacco substitute containing nicotine
KR100526760B1 (ko) 2003-09-05 2005-11-08 김현석 체내 니코틴 분해 효과와 다이옥신의 독성을 감소시키는 효과를 가지는 생약재 추출물의 조성물
AU2004270304A1 (en) 2003-09-05 2005-03-17 Actelion Pharmaceuticals Ltd. Guanidine derivatives
MXPA06002609A (es) 2003-09-08 2006-06-05 Pfizer Health Ab Formulaciones de nicotina y uso de las mismas.
WO2005034968A1 (en) 2003-09-15 2005-04-21 Sanchelima And Associates, P.A. Solution for cessation of smoking and method to use
MXPA06002943A (es) 2003-09-19 2006-05-31 Hoffmann La Roche Derivados de tiazolopiridina como ligandos del receptor de adenosina.
JP4317729B2 (ja) 2003-10-01 2009-08-19 ジ・エコ株式会社 禁煙用靴下とその製造方法
US20050123502A1 (en) * 2003-10-07 2005-06-09 Chan Shing Y. Nicotine containing oral compositions
PT1678172E (pt) * 2003-10-15 2010-03-03 Targacept Inc Composições farmacêuticas e métodos para alívio da dor e tratamento de perturbações do sistema nervoso central
US20050100513A1 (en) * 2003-11-10 2005-05-12 Watkins Mary B. Homeopathic method and system for treating nicotine addiction
US7816356B2 (en) * 2003-11-14 2010-10-19 Daniel Yohannes Aryl and heteroaryltetrahydrocyclobutapyrroles as nicotinic acetylcholine receptor ligands
WO2005053691A2 (en) 2003-12-02 2005-06-16 Fertin Pharma A/S Nicotine delivery product and method for producing it
TW200522944A (en) 2003-12-23 2005-07-16 Lilly Co Eli CB1 modulator compounds
CN1557177A (zh) 2004-02-05 2004-12-29 高永安 含有维生素、抗氧化营养元素、微量元素的胶姆糖
US20050222270A1 (en) 2004-02-26 2005-10-06 Olney John W Prolonged administration of NMDA antagonist drug and safener drug to create improved stable neural homeostasis
IL160753A0 (en) 2004-03-04 2004-08-31 Smoking cessation pacifier
US20050226920A1 (en) * 2004-04-13 2005-10-13 Kirk Voelker Method of decreasing nicotine withdrawal symptoms during smoking cessation.
SE0402258D0 (sv) 2004-05-07 2004-09-17 Katarina Saend Portionssnus
JP2008506788A (ja) 2004-05-21 2008-03-06 アルザ・コーポレーシヨン 多剤形態の送達用の薬用量形態
DE602005004142T2 (de) * 2004-05-24 2009-01-02 F. Hoffmann-La Roche Ag 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4-methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid
US20050277626A1 (en) * 2004-05-27 2005-12-15 Neurocure Ltd. Methods and compositions for treatment of nicotine dependence and dementias
ES2329696T3 (es) 2004-06-29 2009-11-30 Fertin Pharma A/S Goma de mascar que libera alcaloide del tabaco.
US20060062835A1 (en) * 2004-07-19 2006-03-23 Smoke Free In 3, Inc. Multi-disciplinary nicotine craving reduction kit with potentiating homeopathic elements
CN1989117B (zh) 2004-07-22 2011-01-19 弗·哈夫曼-拉罗切有限公司 取代的苯并噻唑
DE602005019408D1 (de) 2004-07-22 2010-04-01 Hoffmann La Roche Benzothiazolderivate
WO2006023630A2 (en) * 2004-08-20 2006-03-02 Targacept, Inc. The use of n-aryl diazaspiracyclic compounds in the treatment of addiction
WO2006028344A1 (en) 2004-09-09 2006-03-16 Industry-Academic Cooperation Foundation Daegu Haany University A composition comprising the purified essential oil extract and lower alcohol soluble extract isolated from angelica gigas for the prevention and treatment of nicotine addiction and withdrawal symptoms
GT200500246A (es) 2004-09-09 2006-04-17 Combinacion de compuestos organicos
WO2006041769A2 (en) 2004-10-05 2006-04-20 Merck & Co., Inc. Methods for the treatment of substance abuse and addiction
DE102004048927A1 (de) 2004-10-06 2006-04-20 Lts Lohmann Therapie-Systeme Ag Pharmazeutische Kombination enthaltend Desoxypeganin und Cyp2D6 Inhibitoren
BRPI0515932A (pt) * 2004-10-15 2008-08-12 Pfizer Prod Inc composições e métodos para distribuição intranasal, bucal, sublingual e pulmonar de vareniclina
DK1817014T3 (da) 2004-11-30 2012-11-19 Fertin Pharma As Fremgangsmåde til ydelse af hurtig afhjælpning til en bruger af et nikotintyggegummi
JP2008530070A (ja) 2005-02-10 2008-08-07 オレクソ・アクチエボラゲット 薬物の経粘膜投与に有用な新規な医薬組成物
WO2006115202A1 (ja) 2005-04-25 2006-11-02 Fuji Sangyo Co., Ltd. ニコチンの毒性軽減組成物
EP1904182A2 (en) * 2005-05-06 2008-04-02 Boehringer Ingelheim International GmbH Method for the treatment of drug abuse with flibanserin
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
US7629342B2 (en) 2005-06-17 2009-12-08 Bristol-Myers Squibb Company Azabicyclic heterocycles as cannabinoid receptor modulators
WO2007006117A1 (en) 2005-07-13 2007-01-18 Nicogen Inc. Novel cyp2a6 inhibitors
US20070134169A1 (en) 2005-12-11 2007-06-14 Rabinoff Michael D Methods for smoking cessation or alcohol cessation or other addiction cessation
JP5694645B2 (ja) 2006-03-16 2015-04-01 ニコノヴァム エービーNiconovum Ab 改善された嗅ぎたばこ組成物
WO2007104574A2 (en) 2006-03-16 2007-09-20 Niconovum Ab Chewing gum compositions providing rapid release of nicotine
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
WO2008069921A2 (en) 2006-12-01 2008-06-12 Cima Labs Inc. Oral transmucosal nicotine dosage form
US20080286340A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
US20080292683A1 (en) 2007-05-24 2008-11-27 Monosolrx, Llc. Film shreds and delivery system incorporating same
US20090081291A1 (en) 2007-09-26 2009-03-26 Gin Jerry B Sustained Release Dosage Forms For Delivery of Agents to an Oral Cavity of a User
US20090098192A1 (en) 2007-10-11 2009-04-16 Fuisz Richard C Extrudable and Extruded Compositions for Delivery of Bioactive Agents, Method of Making Same and Method of Using Same
FR2984713B1 (fr) 2011-12-22 2013-12-27 Seb Sa Appareil electrique culinaire et moyens de securite associes

Also Published As

Publication number Publication date
CN1738621B (zh) 2011-04-27
EP1803444A3 (en) 2007-07-18
EP1578422A2 (en) 2005-09-28
ES2968706T3 (es) 2024-05-13
EP1803444B1 (en) 2018-10-31
KR20050096922A (ko) 2005-10-06
FI3473251T3 (fi) 2024-01-09
EP3473251B1 (en) 2023-12-13
JP4708795B2 (ja) 2011-06-22
EP1578422B1 (en) 2007-04-11
DK1803444T3 (da) 2019-02-25
AU2003293987B2 (en) 2010-09-09
EP1803443B1 (en) 2018-10-31
US9629832B2 (en) 2017-04-25
NO20191286A1 (no) 2005-07-06
ES2708552T3 (es) 2019-04-10
NO344367B1 (no) 2019-11-18
HUE065285T2 (hu) 2024-05-28
NZ540817A (en) 2007-07-27
EP1803444A2 (en) 2007-07-04
WO2004056363A2 (en) 2004-07-08
DE60313216T2 (de) 2008-01-03
US20040191322A1 (en) 2004-09-30
PT1578422E (pt) 2007-06-14
EP1803443A3 (en) 2007-07-18
CA2511185C (en) 2012-09-18
CN1738621A (zh) 2006-02-22
ES2285233T3 (es) 2007-11-16
NO20053309L (no) 2005-07-06
DK1803444T4 (da) 2025-10-27
EP3473251A1 (en) 2019-04-24
JP2006511566A (ja) 2006-04-06
DE60313216D1 (de) 2007-05-24
SI1578422T1 (sl) 2007-12-31
CY1106477T1 (el) 2012-01-25
US8741348B2 (en) 2014-06-03
ATE359075T1 (de) 2007-05-15
ES2708551T3 (es) 2019-04-10
NO346973B1 (en) 2023-03-20
EP1803444B2 (en) 2025-08-06
WO2004056363A3 (en) 2004-10-28
AU2003293987A1 (en) 2004-07-14
CA2511185A1 (en) 2004-07-08
EP1803443A2 (en) 2007-07-04
DK1578422T3 (da) 2007-07-02
US20140234392A1 (en) 2014-08-21
DK1803443T3 (da) 2019-02-25
FI1803444T4 (fi) 2025-10-22

Similar Documents

Publication Publication Date Title
DK3473251T3 (da) Nikotin-cellulose-kombination
ATE457980T1 (de) Aryloxime
ATE534648T1 (de) C-6-modifizierte indazolylpyrrolotriazine
DE60330526D1 (de) Tonerteilchenherstellungsvervahren
ATE318817T1 (de) Aza-arylpiperazine
ATE427876T1 (de) Luftkissenboot
DE50212349D1 (de) Hirurgie
DE50212360D1 (de) Anfahrhilfesteuerungsvorrichtung
DE50301200D1 (de) Wischblatt
ATE349458T1 (de) Etonogestrelester
NO20044118L (no) Alkenseparasjonsfremgangsmate
DE50309536D1 (de) Fadenabsaugvorrichtung
DE50310481D1 (de) Röntgenstativ
DE50307971D1 (de) Gelenklager
DE50302660D1 (de) Stopfmachine
DE50301960D1 (de) Hydrolager
DE50309499D1 (de) Librierwerkzeugen
ATA4142004A (de) Trägerverbau
ATE469773T1 (de) Zugöse
DE50307628D1 (de) Getraenkehalter
DE50303317D1 (de) Einschub-leistungsschalter
ATA19152002A (de) Hubkupplung
DE50209283D1 (de) Tropfbewässerungsrohr
DE50308979D1 (de) Einspritzventil
ATE396192T1 (de) N-sulfonylaminothiazole