IS7662A - Ný þríhringlaga spírópíperídín eða spírópýrrólídín - Google Patents

Ný þríhringlaga spírópíperídín eða spírópýrrólídín

Info

Publication number
IS7662A
IS7662A IS7662A IS7662A IS7662A IS 7662 A IS7662 A IS 7662A IS 7662 A IS7662 A IS 7662A IS 7662 A IS7662 A IS 7662A IS 7662 A IS7662 A IS 7662A
Authority
IS
Iceland
Prior art keywords
spirropiperidine
spiropyrrolidine
new tricyclic
tricyclic
new
Prior art date
Application number
IS7662A
Other languages
English (en)
Inventor
Hossain Nafizal
Ivanova Svetlana
Mensonides-Harsema Marguerite
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS7662A publication Critical patent/IS7662A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IS7662A 2002-07-08 2005-01-24 Ný þríhringlaga spírópíperídín eða spírópýrrólídín IS7662A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0202133A SE0202133D0 (sv) 2002-07-08 2002-07-08 Novel compounds
PCT/SE2003/001185 WO2004005295A1 (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines

Publications (1)

Publication Number Publication Date
IS7662A true IS7662A (is) 2005-01-24

Family

ID=20288470

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7662A IS7662A (is) 2002-07-08 2005-01-24 Ný þríhringlaga spírópíperídín eða spírópýrrólídín

Country Status (25)

Country Link
US (2) US7449475B2 (is)
EP (1) EP1521757B1 (is)
JP (1) JP2005537255A (is)
CN (2) CN1974574A (is)
AR (1) AR040475A1 (is)
AT (1) ATE385235T1 (is)
AU (1) AU2003243122B2 (is)
BR (1) BR0312560A (is)
CA (1) CA2492122A1 (is)
CY (1) CY1107915T1 (is)
DE (1) DE60318948T2 (is)
DK (1) DK1521757T3 (is)
ES (1) ES2298575T3 (is)
IS (1) IS7662A (is)
MX (1) MXPA05000278A (is)
NO (1) NO20050635L (is)
NZ (1) NZ537259A (is)
PL (1) PL374877A1 (is)
PT (1) PT1521757E (is)
RU (1) RU2320664C2 (is)
SE (1) SE0202133D0 (is)
TW (1) TW200413386A (is)
UA (1) UA77809C2 (is)
WO (1) WO2004005295A1 (is)
ZA (1) ZA200500024B (is)

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US20070021498A1 (en) * 2004-10-14 2007-01-25 Nafizal Hossain Novel tricyclic spiroderivatives as modulators of chemokine receptor activity
SE0302755D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel compounds
SE0302811D0 (sv) * 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
SE0303090D0 (sv) * 2003-11-20 2003-11-20 Astrazeneca Ab Novel compounds
SE0303280D0 (sv) * 2003-12-05 2003-12-05 Astrazeneca Ab Novel compounds
SE0303541D0 (sv) * 2003-12-22 2003-12-22 Astrazeneca Ab New compounds
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
CA2570637A1 (en) 2004-06-24 2006-02-02 Wenqing Yao N-substituted piperidines and their use as pharmaceuticals
EP1883402A2 (en) 2005-04-13 2008-02-06 Astex Therapeutics Limited Hydroxybenzamide derivatives and their use as inhibitors of hsp90
JP2009507800A (ja) 2005-09-09 2009-02-26 ユーロ−セルティーク エス．エイ． 縮合およびスピロ環化合物ならびにその使用
JP5315590B2 (ja) * 2006-02-14 2013-10-16 Ｊｎｃ株式会社 液晶化合物、液晶組成物および液晶表示素子
US7754725B2 (en) 2006-03-01 2010-07-13 Astex Therapeutics Ltd. Dihydroxyphenyl isoindolymethanones
TW200821316A (en) * 2006-07-19 2008-05-16 Astrazeneca Ab Novel compounds 243
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
WO2008044054A2 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Hydroxy-substituted benzoic acid amide compounds for use in therapy
EP2081891A2 (en) 2006-10-12 2009-07-29 Astex Therapeutics Limited Pharmaceutical compounds having hsp90 inhibitory or modulating activity
JP5721949B2 (ja) 2006-10-12 2015-05-20 アステックス、セラピューティックス、リミテッドＡｓｔｅｘ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ 複合薬剤
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JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8012955B2 (en) 2006-12-28 2011-09-06 Rigel Pharmaceuticals, Inc. N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
US20110124613A1 (en) * 2007-02-23 2011-05-26 Tomas Eriksson Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma
US20110136843A1 (en) * 2007-02-23 2011-06-09 Tomas Eriksson Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma
WO2008121066A1 (en) * 2007-03-30 2008-10-09 Astrazeneca Ab Novel tricyclic spiropiperidines or spiropyrrolidines and their use as modulators of chemokine receptors
PE20090829A1 (es) * 2007-06-20 2009-07-25 Glaxo Group Ltd Espiroindolinas como moduladores de receptores de quimioquinas
WO2009011655A1 (en) * 2007-07-17 2009-01-22 Astrazeneca Ab Splropiperidine compounds, a process of their preparation, pharmaceutical compositions containing them, and their use in the treatment of airway diseases, inflammatory diseases, copd or asthma
WO2009011653A1 (en) * 2007-07-17 2009-01-22 Astrazeneca Ab A process for the preparation of intermediates and their us in the synthesis of spiropiperidine compounds
CN101808990B (zh) * 2007-07-24 2012-09-05 百时美施贵宝公司 作为趋化因子受体活性调节剂的哌啶衍生物
EP2190286A4 (en) * 2007-08-14 2011-06-01 Glaxo Group Ltd SPIROINDENES AND SPIROINDANES AS MODULATORS OF CHEMOKINE RECEPTORS
WO2009061881A1 (en) * 2007-11-07 2009-05-14 Glaxo Group Limited Spirodihydrobenzofurans as modulators of chemokine receptors
CA2712897A1 (en) * 2008-01-30 2009-08-06 Pharmacopeia, Inc. Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands
FR2928150A1 (fr) 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
GB0806527D0 (en) 2008-04-11 2008-05-14 Astex Therapeutics Ltd Pharmaceutical compounds
EP2145891A1 (en) 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
AR078948A1 (es) * 2009-11-30 2011-12-14 Lilly Co Eli Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands
EP3668840A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Novel sulfonamide carboxamide compounds
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Also Published As

Publication number Publication date
ES2298575T3 (es) 2008-05-16
TW200413386A (en) 2004-08-01
ZA200500024B (en) 2006-02-22
UA77809C2 (en) 2007-01-15
CN1974574A (zh) 2007-06-06
CN1675218A (zh) 2005-09-28
CN1326858C (zh) 2007-07-18
US7449475B2 (en) 2008-11-11
JP2005537255A (ja) 2005-12-08
PT1521757E (pt) 2008-04-03
US20050245741A1 (en) 2005-11-03
NZ537259A (en) 2006-08-31
ATE385235T1 (de) 2008-02-15
US20090062322A1 (en) 2009-03-05
AU2003243122A1 (en) 2004-01-23
DK1521757T3 (da) 2008-05-05
RU2320664C2 (ru) 2008-03-27
MXPA05000278A (es) 2005-03-31
WO2004005295A1 (en) 2004-01-15
AR040475A1 (es) 2005-04-06
EP1521757B1 (en) 2008-01-30
AU2003243122B2 (en) 2006-09-28
RU2004137278A (ru) 2005-09-10
NO20050635L (no) 2005-03-31
PL374877A1 (en) 2005-11-14
EP1521757A1 (en) 2005-04-13
SE0202133D0 (sv) 2002-07-08
HK1074622A1 (en) 2005-11-18
CA2492122A1 (en) 2004-01-15
BR0312560A (pt) 2005-05-10
DE60318948D1 (de) 2008-03-20
DE60318948T2 (de) 2009-05-20
CY1107915T1 (el) 2013-09-04

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