ATE385500T1 - Verfahren zur herstellung von zwischenprodukten für die verwendung bei der cefalosporinsynthese - Google Patents

Verfahren zur herstellung von zwischenprodukten für die verwendung bei der cefalosporinsynthese

Info

Publication number: ATE385500T1
Authority: AT; Austria
Prior art keywords: formula; compound; synthesis; cefalosporin; intermediate products
Prior art date: 2003-12-23

Application number

AT04804240T

Other languages

English (en)

Inventor

Johannes Ludescher

Hubert Sturm

Katja Vorndran

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-23

Filing date

2004-12-22

Publication date

2008-02-15

2004-12-22 Application filed by Sandoz Ag filed Critical Sandoz Ag

2008-02-15 Application granted granted Critical

2008-02-15 Publication of ATE385500T1 publication Critical patent/ATE385500T1/de

Links

230000015572 biosynthetic process Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000003786 synthesis reaction Methods 0.000 title abstract 2
239000013067 intermediate product Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
239000000543 intermediate Substances 0.000 abstract 2
229930186147 Cephalosporin Natural products 0.000 abstract 1
HVFLCNVBZFFHBT-ZKDACBOMSA-N cefepime Chemical compound S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1C[N+]1(C)CCCC1 HVFLCNVBZFFHBT-ZKDACBOMSA-N 0.000 abstract 1
229960002100 cefepime Drugs 0.000 abstract 1
229940124587 cephalosporin Drugs 0.000 abstract 1
150000001780 cephalosporins Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
239000003586 protic polar solvent Substances 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)

AT04804240T 2003-12-23 2004-12-22 Verfahren zur herstellung von zwischenprodukten für die verwendung bei der cefalosporinsynthese ATE385500T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT20762003		2003-12-23
AT2004014646		2004-12-22

Publications (1)

Publication Number	Publication Date
ATE385500T1 true ATE385500T1 (de)	2008-02-15

Family

ID=34716003

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04804240T ATE385500T1 (de)	2003-12-23	2004-12-22	Verfahren zur herstellung von zwischenprodukten für die verwendung bei der cefalosporinsynthese

Country Status (9)

Country	Link
US (1)	US7592447B2 (de)
EP (1)	EP1699804B1 (de)
JP (1)	JP4616844B2 (de)
CN (1)	CN100543027C (de)
AT (1)	ATE385500T1 (de)
DE (1)	DE602004011685T2 (de)
ES (1)	ES2298850T3 (de)
SI (1)	SI1699804T1 (de)
WO (1)	WO2005063772A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20070111980A1 (en) *	2004-07-16	2007-05-17	Bandi Parthasaradhi Reddy	Process for preparing pure cephalosporine intermediates
WO2006075244A2 (en) *	2005-01-17	2006-07-20	Orchid Chemicals & Pharmaceuticals Ltd	Improved process for the preparation of cephalosporin antibiotic intermediate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6011917B2 (ja) *	1981-04-09	1985-03-28	山之内製薬株式会社	新規なセファロスポリン化合物
US4406899A (en) *	1982-03-04	1983-09-27	Bristol-Myers Company	Cephalosporins
CA1213882A (en) *	1982-03-04	1986-11-12	Jun Okumura	Cephalosporins
GB2165245B (en)	1984-10-01	1988-05-25	Glaxo Group Ltd	Chemical compounds
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds
CA1284994C (en)	1985-08-05	1991-06-18	Murray Arthur Kaplan	Cephalosporin salts and injectable compositions
CA2099692C (en) *	1992-07-24	2003-09-30	Gary M. F. Lim	Process for preparing cephalosporin intermediates
JPH06234768A (ja)	1993-02-12	1994-08-23	Sumitomo Electric Ind Ltd	有機電荷移動錯体
US20070111980A1 (en) *	2004-07-16	2007-05-17	Bandi Parthasaradhi Reddy	Process for preparing pure cephalosporine intermediates

2004
- 2004-12-22 DE DE602004011685T patent/DE602004011685T2/de not_active Expired - Lifetime
- 2004-12-22 AT AT04804240T patent/ATE385500T1/de active
- 2004-12-22 CN CNB2004800384576A patent/CN100543027C/zh not_active Expired - Fee Related
- 2004-12-22 EP EP04804240A patent/EP1699804B1/de not_active Expired - Lifetime
- 2004-12-22 JP JP2006546070A patent/JP4616844B2/ja not_active Expired - Fee Related
- 2004-12-22 ES ES04804240T patent/ES2298850T3/es not_active Expired - Lifetime
- 2004-12-22 US US10/583,159 patent/US7592447B2/en not_active Expired - Fee Related
- 2004-12-22 SI SI200430698T patent/SI1699804T1/sl unknown
- 2004-12-22 WO PCT/EP2004/014646 patent/WO2005063772A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP1699804A1 (de)	2006-09-13
JP2007515453A (ja)	2007-06-14
WO2005063772A1 (en)	2005-07-14
DE602004011685D1 (de)	2008-03-20
DE602004011685T2 (de)	2009-02-05
SI1699804T1 (sl)	2008-08-31
CN100543027C (zh)	2009-09-23
ES2298850T3 (es)	2008-05-16
US7592447B2 (en)	2009-09-22
JP4616844B2 (ja)	2011-01-19
CN1898250A (zh)	2007-01-17
EP1699804B1 (de)	2008-02-06
US20070191601A1 (en)	2007-08-16

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