ATE385574T1 - Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen - Google Patents
Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungenInfo
- Publication number
- ATE385574T1 ATE385574T1 AT03706157T AT03706157T ATE385574T1 AT E385574 T1 ATE385574 T1 AT E385574T1 AT 03706157 T AT03706157 T AT 03706157T AT 03706157 T AT03706157 T AT 03706157T AT E385574 T1 ATE385574 T1 AT E385574T1
- Authority
- AT
- Austria
- Prior art keywords
- cell sample
- melatonin
- signaling pathway
- idiopathic scoliosis
- related diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000015686 juvenile idiopathic scoliosis Diseases 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 4
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 4
- 229960003987 melatonin Drugs 0.000 abstract 4
- 230000019491 signal transduction Effects 0.000 abstract 4
- 208000022567 adolescent idiopathic scoliosis Diseases 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000003098 myoblast Anatomy 0.000 abstract 1
- 210000000963 osteoblast Anatomy 0.000 abstract 1
- 210000002997 osteoclast Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Testing Of Engines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002373854A CA2373854A1 (en) | 2002-02-28 | 2002-02-28 | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE385574T1 true ATE385574T1 (de) | 2008-02-15 |
Family
ID=27762090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03706157T ATE385574T1 (de) | 2002-02-28 | 2003-02-28 | Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US20050130250A1 (de) |
| EP (1) | EP1478928B1 (de) |
| AT (1) | ATE385574T1 (de) |
| AU (1) | AU2003208204A1 (de) |
| CA (1) | CA2373854A1 (de) |
| CY (1) | CY1107358T1 (de) |
| DE (1) | DE60318987T2 (de) |
| DK (1) | DK1478928T3 (de) |
| ES (1) | ES2298498T3 (de) |
| PT (1) | PT1478928E (de) |
| WO (1) | WO2003073102A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373854A1 (en) | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| US20090035772A1 (en) * | 2007-07-03 | 2009-02-05 | Axial Biotech, Inc. | Genetic Markers Associated With Scoliosis And Uses Thereof |
| US20090035769A1 (en) * | 2007-12-31 | 2009-02-05 | Nelson Lesa M | Genetic Markers Associated with Scoliosis and Uses Thereof |
| US20090104620A1 (en) * | 2007-07-03 | 2009-04-23 | Axial Biotech, Inc. | Simplified Method of Determining Predisposition to Scoliosis |
| US7655403B2 (en) * | 2006-12-02 | 2010-02-02 | Texas Scottish Rite Hospital For Children | CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis |
| AU2008229601B2 (en) * | 2007-03-19 | 2013-05-02 | Chu Sainte-Justine | Methods of stratifying adolescent idiopathic scoliosis, isolated nucleic acid molecules for use in same and kits using same |
| US20100075333A1 (en) * | 2007-03-30 | 2010-03-25 | Alain Moreau | Method of determining the risk of scoliosis |
| TWI443337B (zh) * | 2008-10-10 | 2014-07-01 | Ct Hospitalier Universitaire Sainte Justine | 用於脊柱側彎之分類及診斷的方法 |
| ES2616808T3 (es) * | 2010-10-04 | 2017-06-14 | Chu Sainte-Justine | Métodos de base biomecánica de diagnóstico de escoliosis |
| EP3010541B1 (de) | 2013-06-17 | 2019-04-10 | Chu Sainte-Justine | Verfahren zur diagnostik einer skoliotischen person |
| KR20160020552A (ko) | 2013-06-17 | 2016-02-23 | 슈 생-쥐스땡 | 척추측만증 및 척추측만증 진행에 대한 마커로서 Gi 단백질 인산화, 척추측만 개체에서 GiPCR 신호전달을 증가시키는 방법 |
| EP3011332B1 (de) | 2013-06-17 | 2019-09-18 | CHU Sainte-Justine | Neue marker des schwierigen verlaufs von idiopathischer skoliose und verwendungen davon zur unterteilung von skoliosepatienten und zur vorhersage des risikos der entwicklung von skoliose |
| WO2015032004A1 (en) | 2013-09-09 | 2015-03-12 | Chu Sainte-Justine | Method of treating and prognosing scoliotic patient subgroups |
| MX382711B (es) | 2014-09-25 | 2025-03-13 | Biora Therapeutics Inc | Dispositivo de pildora electromecanica con capacidades de localizacion. |
| CA2989480C (en) * | 2015-06-16 | 2024-03-05 | Centro De Investigacion Biomedica En Red (Ciber) | Kit and method for the diagnosis/prognosis of idiopathic scoliosis |
| JP7153633B2 (ja) * | 2016-08-18 | 2022-10-14 | ビオラ・セラピューティクス・インコーポレイテッド | サンプリングシステム、ならびに関連する材料および方法 |
| CN115591091A (zh) | 2016-09-09 | 2023-01-13 | 比奥拉治疗股份有限公司（Us） | 用于递送可配发物质的机电可摄入装置 |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP3600009B1 (de) | 2017-03-31 | 2020-12-30 | Progenity, Inc. | Schluckbare vorrichtung mit lokalisierungsfähigkeit |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| CN111575361A (zh) * | 2020-04-20 | 2020-08-25 | 孙欣 | 一种褪黑素通路调控因子治疗ais患者的测试方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856124A (en) * | 1994-06-17 | 1999-01-05 | The General Hospital Corporation | DNA encoding high-affinity melatonin receptors |
| DE69735852D1 (de) * | 1996-07-18 | 2006-06-14 | Gen Hospital Corp | Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen |
| JPH119282A (ja) * | 1997-06-19 | 1999-01-19 | Nippon Chem Res Kk | メラトニン受容体発現細胞とその用途 |
| AU6385200A (en) * | 1999-07-30 | 2001-02-19 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for prognostication, diagnosis, prevention, and treatment of bone-related disorders and other disorders |
| CA2373854A1 (en) | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
-
2002
- 2002-02-28 CA CA002373854A patent/CA2373854A1/en not_active Abandoned
-
2003
- 2003-02-28 PT PT03706157T patent/PT1478928E/pt unknown
- 2003-02-28 EP EP03706157A patent/EP1478928B1/de not_active Expired - Lifetime
- 2003-02-28 AU AU2003208204A patent/AU2003208204A1/en not_active Abandoned
- 2003-02-28 DE DE60318987T patent/DE60318987T2/de not_active Expired - Lifetime
- 2003-02-28 WO PCT/CA2003/000286 patent/WO2003073102A1/en not_active Ceased
- 2003-02-28 ES ES03706157T patent/ES2298498T3/es not_active Expired - Lifetime
- 2003-02-28 AT AT03706157T patent/ATE385574T1/de not_active IP Right Cessation
- 2003-02-28 DK DK03706157T patent/DK1478928T3/da active
- 2003-02-28 US US10/505,951 patent/US20050130250A1/en not_active Abandoned
-
2008
- 2008-03-24 CY CY20081100337T patent/CY1107358T1/el unknown
- 2008-09-11 US US12/232,141 patent/US7989175B2/en not_active Expired - Fee Related
-
2011
- 2011-06-21 US US13/165,404 patent/US20120009600A1/en not_active Abandoned
- 2011-06-21 US US13/165,226 patent/US20110256582A1/en not_active Abandoned
-
2012
- 2012-12-24 US US13/726,416 patent/US8652791B2/en not_active Expired - Fee Related
-
2013
- 2013-12-30 US US14/143,811 patent/US20140113313A1/en not_active Abandoned
-
2016
- 2016-05-19 US US15/159,222 patent/US20160258947A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DK1478928T3 (da) | 2008-05-19 |
| AU2003208204A1 (en) | 2003-09-09 |
| EP1478928B1 (de) | 2008-02-06 |
| US7989175B2 (en) | 2011-08-02 |
| US8652791B2 (en) | 2014-02-18 |
| US20160258947A1 (en) | 2016-09-08 |
| US20050130250A1 (en) | 2005-06-16 |
| DE60318987D1 (de) | 2008-03-20 |
| US20090111110A1 (en) | 2009-04-30 |
| CA2373854A1 (en) | 2003-08-28 |
| US20120009600A1 (en) | 2012-01-12 |
| US20110256582A1 (en) | 2011-10-20 |
| DE60318987T2 (de) | 2009-01-29 |
| WO2003073102A1 (en) | 2003-09-04 |
| ES2298498T3 (es) | 2008-05-16 |
| HK1071601A1 (en) | 2005-07-22 |
| US20130115615A1 (en) | 2013-05-09 |
| US20140113313A1 (en) | 2014-04-24 |
| EP1478928A1 (de) | 2004-11-24 |
| PT1478928E (pt) | 2008-04-09 |
| CY1107358T1 (el) | 2012-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1478928 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |