ATE385574T1 - Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen - Google Patents
Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungenInfo
- Publication number
- ATE385574T1 ATE385574T1 AT03706157T AT03706157T ATE385574T1 AT E385574 T1 ATE385574 T1 AT E385574T1 AT 03706157 T AT03706157 T AT 03706157T AT 03706157 T AT03706157 T AT 03706157T AT E385574 T1 ATE385574 T1 AT E385574T1
- Authority
- AT
- Austria
- Prior art keywords
- cell sample
- melatonin
- signaling pathway
- idiopathic scoliosis
- related diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000015686 juvenile idiopathic scoliosis Diseases 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 4
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 4
- 229960003987 melatonin Drugs 0.000 abstract 4
- 230000019491 signal transduction Effects 0.000 abstract 4
- 208000022567 adolescent idiopathic scoliosis Diseases 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000003098 myoblast Anatomy 0.000 abstract 1
- 210000000963 osteoblast Anatomy 0.000 abstract 1
- 210000002997 osteoclast Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Testing Of Engines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002373854A CA2373854A1 (en) | 2002-02-28 | 2002-02-28 | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE385574T1 true ATE385574T1 (de) | 2008-02-15 |
Family
ID=27762090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03706157T ATE385574T1 (de) | 2002-02-28 | 2003-02-28 | Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US20050130250A1 (de) |
| EP (1) | EP1478928B1 (de) |
| AT (1) | ATE385574T1 (de) |
| AU (1) | AU2003208204A1 (de) |
| CA (1) | CA2373854A1 (de) |
| CY (1) | CY1107358T1 (de) |
| DE (1) | DE60318987T2 (de) |
| DK (1) | DK1478928T3 (de) |
| ES (1) | ES2298498T3 (de) |
| PT (1) | PT1478928E (de) |
| WO (1) | WO2003073102A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373854A1 (en) | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| US20090104620A1 (en) * | 2007-07-03 | 2009-04-23 | Axial Biotech, Inc. | Simplified Method of Determining Predisposition to Scoliosis |
| US20090035769A1 (en) * | 2007-12-31 | 2009-02-05 | Nelson Lesa M | Genetic Markers Associated with Scoliosis and Uses Thereof |
| US20090035772A1 (en) * | 2007-07-03 | 2009-02-05 | Axial Biotech, Inc. | Genetic Markers Associated With Scoliosis And Uses Thereof |
| US7655403B2 (en) * | 2006-12-02 | 2010-02-02 | Texas Scottish Rite Hospital For Children | CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis |
| WO2008113174A1 (en) * | 2007-03-19 | 2008-09-25 | Chu Sainte-Justine | Methods of stratifying adolescent idiopathic scoliosis, isolated nucleic acid molecules for use in same and kits using same |
| MX2009010400A (es) | 2007-03-30 | 2010-02-18 | Chu Sainte Justine | Método para la determinacion de riesgo de escoliosis. |
| TWI443337B (zh) * | 2008-10-10 | 2014-07-01 | Ct Hospitalier Universitaire Sainte Justine | 用於脊柱側彎之分類及診斷的方法 |
| EP2598875B1 (de) * | 2010-10-04 | 2016-12-07 | Chu Sainte-Justine | Verfahren zur skoliose-diagnose auf biomechanischer basis |
| CA2914213A1 (en) | 2013-06-17 | 2014-12-24 | Alain Moreau | A method of increasing gipcr signalization in the cells of a scoliotic subject |
| US20160139146A1 (en) | 2013-06-17 | 2016-05-19 | Chu Sainte-Justine | Gi protein phosphorylation as marker for scoliosis and scoliosis progression, methods of increasing gipcr signaling in scoliotic subjects |
| WO2014201560A1 (en) | 2013-06-17 | 2014-12-24 | Chu Ste-Justine | New markers for severe progression of idiopathic scoliosis and uses thereof to stratify scoliotic patients and predict the risk of developing scoliosis |
| US10247737B2 (en) | 2013-09-09 | 2019-04-02 | Chu Sainte-Justine | Kits for classifying a subject having or at risk for developing idiopathic scoliosis |
| KR102397233B1 (ko) | 2014-09-25 | 2022-05-12 | 프로제너티, 인크. | 위치추정 능력을 갖는 전기기계 알약 장치 |
| CA2989480C (en) | 2015-06-16 | 2024-03-05 | Centro De Investigacion Biomedica En Red (Ciber) | Kit and method for the diagnosis/prognosis of idiopathic scoliosis |
| EP3500177A1 (de) * | 2016-08-18 | 2019-06-26 | Mitchell Lawrence Jones | Systeme zur gewinnung von proben mithilfe einnehmbarer vorrichtungen |
| JP2019526423A (ja) | 2016-09-09 | 2019-09-19 | ミッチェル・ローレンス・ジョーンズＭｉｔｃｈｅｌｌ Ｌａｗｒｅｎｃｅ ＪＯＮＥＳ | 分注可能物質の送達のための電気機械的摂取可能装置 |
| WO2018106945A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| KR102329597B1 (ko) | 2017-03-31 | 2021-11-23 | 프로제너티, 인크. | 섭취가능한 디바이스용 측위 시스템 및 방법 |
| EP3883635A1 (de) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Verfahren und vorrichtungen zur behandlung einer krankheit mit biotherapeutika |
| CN111575361A (zh) * | 2020-04-20 | 2020-08-25 | 孙欣 | 一种褪黑素通路调控因子治疗ais患者的测试方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856124A (en) * | 1994-06-17 | 1999-01-05 | The General Hospital Corporation | DNA encoding high-affinity melatonin receptors |
| DE69735852D1 (de) * | 1996-07-18 | 2006-06-14 | Gen Hospital Corp | Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen |
| JPH119282A (ja) * | 1997-06-19 | 1999-01-19 | Nippon Chem Res Kk | メラトニン受容体発現細胞とその用途 |
| AU6385200A (en) * | 1999-07-30 | 2001-02-19 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for prognostication, diagnosis, prevention, and treatment of bone-related disorders and other disorders |
| CA2373854A1 (en) * | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
-
2002
- 2002-02-28 CA CA002373854A patent/CA2373854A1/en not_active Abandoned
-
2003
- 2003-02-28 WO PCT/CA2003/000286 patent/WO2003073102A1/en not_active Ceased
- 2003-02-28 PT PT03706157T patent/PT1478928E/pt unknown
- 2003-02-28 DK DK03706157T patent/DK1478928T3/da active
- 2003-02-28 EP EP03706157A patent/EP1478928B1/de not_active Expired - Lifetime
- 2003-02-28 ES ES03706157T patent/ES2298498T3/es not_active Expired - Lifetime
- 2003-02-28 AU AU2003208204A patent/AU2003208204A1/en not_active Abandoned
- 2003-02-28 US US10/505,951 patent/US20050130250A1/en not_active Abandoned
- 2003-02-28 AT AT03706157T patent/ATE385574T1/de not_active IP Right Cessation
- 2003-02-28 DE DE60318987T patent/DE60318987T2/de not_active Expired - Lifetime
-
2008
- 2008-03-24 CY CY20081100337T patent/CY1107358T1/el unknown
- 2008-09-11 US US12/232,141 patent/US7989175B2/en not_active Expired - Fee Related
-
2011
- 2011-06-21 US US13/165,226 patent/US20110256582A1/en not_active Abandoned
- 2011-06-21 US US13/165,404 patent/US20120009600A1/en not_active Abandoned
-
2012
- 2012-12-24 US US13/726,416 patent/US8652791B2/en not_active Expired - Fee Related
-
2013
- 2013-12-30 US US14/143,811 patent/US20140113313A1/en not_active Abandoned
-
2016
- 2016-05-19 US US15/159,222 patent/US20160258947A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1478928B1 (de) | 2008-02-06 |
| DE60318987T2 (de) | 2009-01-29 |
| DE60318987D1 (de) | 2008-03-20 |
| US20160258947A1 (en) | 2016-09-08 |
| CY1107358T1 (el) | 2012-12-19 |
| US20110256582A1 (en) | 2011-10-20 |
| EP1478928A1 (de) | 2004-11-24 |
| CA2373854A1 (en) | 2003-08-28 |
| US20090111110A1 (en) | 2009-04-30 |
| US7989175B2 (en) | 2011-08-02 |
| WO2003073102A1 (en) | 2003-09-04 |
| HK1071601A1 (en) | 2005-07-22 |
| DK1478928T3 (da) | 2008-05-19 |
| US20140113313A1 (en) | 2014-04-24 |
| US20130115615A1 (en) | 2013-05-09 |
| ES2298498T3 (es) | 2008-05-16 |
| AU2003208204A1 (en) | 2003-09-09 |
| US8652791B2 (en) | 2014-02-18 |
| PT1478928E (pt) | 2008-04-09 |
| US20050130250A1 (en) | 2005-06-16 |
| US20120009600A1 (en) | 2012-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE385574T1 (de) | Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen | |
| CY1109106T1 (el) | Εγκαιρη διαγνωση ασθενειων διαταραχης διαμορφωσης πρωτεϊνων | |
| DE69938662D1 (de) | Spurendetektion von analyten mit hilfe artifizieller olfaktometrie | |
| EP1563300A4 (de) | Diagnoseverfahren für sprue/zeliakie | |
| DE602005013957D1 (de) | Verfahren zur durchführung von vollbluttests | |
| ATE310955T1 (de) | Zusammensetzungen und verfahren zum nachweis und zur behandlung von mit chemokinrezeptoren verbundenen krankheiten | |
| EP2520935A3 (de) | Organspezifische Proteine und Verfahren zu deren Verwendung | |
| DE602004026014D1 (de) | Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben | |
| ATE515575T1 (de) | Verfahren und sonden für den nachweis von krebs | |
| WO2002093129A3 (en) | Methods for analyzing interactions between proteins in live and intact cells | |
| ATE418072T1 (de) | Verfahren zur diagnose von gebärmutterhalskrebs | |
| EP1543331A4 (de) | Verfahren zur diagnose von morbus alzheimer | |
| DE60331857D1 (de) | Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit | |
| ATE514948T1 (de) | In vitro verfahren zur diagnose von neurodegenerativen erkrankungen | |
| EP2508886A3 (de) | Mittel und Verfahren zur Klassifizierung von Proben von Multiple-Sklerose-Patienten. | |
| ATE326982T1 (de) | Testsystem zur evaluierung der kompatibilität biologisch aktiver substanzen mit copolymeren | |
| FI990380A7 (fi) | Diagnostinen ja seulontamenetelmä | |
| DE602005013430D1 (de) | Verwendung von asc als marker für kolorektalkarzinome | |
| DE69912453D1 (de) | Verfahren und materialien zur diagnose instabiler angina | |
| ATE403739T1 (de) | Verfahren zur verwendung teilungsarretierter zellen in screening-assays | |
| ATA19972000A (de) | Pibf für die diagnose von tumoren | |
| SE0200974D0 (sv) | Screening method for gastritis | |
| ATE408827T1 (de) | Quantifizierung von stressbelastung | |
| ATE550662T1 (de) | Diagnose- und behandlungsverfahren sowie dafür geeignete mittel | |
| ATE461452T1 (de) | Verfahren zum nachweis von menschlichem parvovirus-antigen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1478928 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |