ATE386128T1 - Nicht-pathogenes kinetoplastid protein- expressionssystem - Google Patents

Nicht-pathogenes kinetoplastid protein- expressionssystem

Info

Publication number
ATE386128T1
ATE386128T1 AT00983103T AT00983103T ATE386128T1 AT E386128 T1 ATE386128 T1 AT E386128T1 AT 00983103 T AT00983103 T AT 00983103T AT 00983103 T AT00983103 T AT 00983103T AT E386128 T1 ATE386128 T1 AT E386128T1
Authority
AT
Austria
Prior art keywords
leptomonas
kinetoplastid
pathogene
protein expression
inconstans
Prior art date
Application number
AT00983103T
Other languages
English (en)
Inventor
Kirill Alexandrov
Mathias Grun
Original Assignee
Jena Bioscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jena Bioscience Gmbh filed Critical Jena Bioscience Gmbh
Application granted granted Critical
Publication of ATE386128T1 publication Critical patent/ATE386128T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
    • C12N2840/445—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor for trans-splicing, e.g. polypyrimidine tract, branch point splicing

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00983103T 1999-11-05 2000-11-02 Nicht-pathogenes kinetoplastid protein- expressionssystem ATE386128T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99122222 1999-11-05

Publications (1)

Publication Number Publication Date
ATE386128T1 true ATE386128T1 (de) 2008-03-15

Family

ID=8239347

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00983103T ATE386128T1 (de) 1999-11-05 2000-11-02 Nicht-pathogenes kinetoplastid protein- expressionssystem

Country Status (9)

Country Link
EP (1) EP1242602B1 (de)
JP (1) JP2003513632A (de)
AT (1) ATE386128T1 (de)
AU (1) AU1997901A (de)
CA (1) CA2388151C (de)
DE (1) DE60038045T2 (de)
DK (1) DK1242602T3 (de)
ES (1) ES2301495T3 (de)
WO (1) WO2001032896A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2362383B (en) * 2000-05-19 2003-12-31 Devgen Nv Gene expression system
DE10214406A1 (de) * 2002-03-30 2003-10-09 Nutrinova Gmbh Verfahren und Marker zur einfachen Transformation und Selektion von rekombinanten Protisten
US7261887B2 (en) 2002-11-12 2007-08-28 Rosalind Franklin University Of Medicine And Science Leishmania as carriers for the delivery of proteins and peptides
EP2412382A1 (de) 2010-07-29 2012-02-01 University Court of the University of Edinburgh Rekombinanter Trypanosoma theileri-Parasit
EP2740791A1 (de) * 2012-12-05 2014-06-11 MicroCoat Biotechnologie GmbH Verfahren für die rekombinante Herstellung von Pfeilschwanzkrebs-Faktor-C-Protein in Protozoen
GB201508025D0 (en) 2015-05-11 2015-06-24 Ucl Business Plc Fabry disease gene therapy
JP7437162B2 (ja) * 2017-06-30 2024-02-22 リンマテック バイオロジクス エージー 改変されかつ完全に機能カスタマイズされた糖タンパク質
PL240561B1 (pl) * 2017-10-09 2022-05-02 Gdanski Univ Medyczny Wektory DNA zdolne do transformacji i integracji z chromosomem Leishmania tarentolae zawierające gen kodujący butyrylocholinoesterazę BChE
CA3166728A1 (en) * 2020-01-07 2021-07-15 Limmatech Biologics Ag Engineered leishmania cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62282585A (ja) * 1986-05-31 1987-12-08 Sanraku Inc ハイブリツドプラスミド
JP3172710B2 (ja) * 1997-07-07 2001-06-04 理化学研究所 Ｒｎａポリメラーゼ
AU1840000A (en) * 1998-12-02 2000-06-19 Nisha Garg Kinetoplastid protein expression system
US20010010928A1 (en) * 1999-03-26 2001-08-02 Stephen M. Beverley Protozoan expression system

Also Published As

Publication number Publication date
DK1242602T3 (da) 2008-06-02
DE60038045T2 (de) 2009-02-05
DE60038045D1 (de) 2008-03-27
CA2388151C (en) 2010-01-12
EP1242602A1 (de) 2002-09-25
WO2001032896A1 (en) 2001-05-10
JP2003513632A (ja) 2003-04-15
AU1997901A (en) 2001-05-14
CA2388151A1 (en) 2001-05-10
ES2301495T3 (es) 2008-07-01
EP1242602B1 (de) 2008-02-13

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