ATE386128T1 - Nicht-pathogenes kinetoplastid protein- expressionssystem - Google Patents
Nicht-pathogenes kinetoplastid protein- expressionssystemInfo
- Publication number
- ATE386128T1 ATE386128T1 AT00983103T AT00983103T ATE386128T1 AT E386128 T1 ATE386128 T1 AT E386128T1 AT 00983103 T AT00983103 T AT 00983103T AT 00983103 T AT00983103 T AT 00983103T AT E386128 T1 ATE386128 T1 AT E386128T1
- Authority
- AT
- Austria
- Prior art keywords
- leptomonas
- kinetoplastid
- pathogene
- protein expression
- inconstans
- Prior art date
Links
- 241000222712 Kinetoplastida Species 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
- 241000382814 Wallaceina inconstans Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000222718 Crithidia fasciculata Species 0.000 abstract 1
- 241000222702 Leishmania tarentolae Species 0.000 abstract 1
- 241000222698 Leptomonas Species 0.000 abstract 1
- 241000222699 Leptomonas seymouri Species 0.000 abstract 1
- 241000222700 Leptomonas sp. Species 0.000 abstract 1
- 241000409490 Leptomonas sp. Cfm Species 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
- C12N2840/445—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor for trans-splicing, e.g. polypyrimidine tract, branch point splicing
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99122222 | 1999-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE386128T1 true ATE386128T1 (de) | 2008-03-15 |
Family
ID=8239347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00983103T ATE386128T1 (de) | 1999-11-05 | 2000-11-02 | Nicht-pathogenes kinetoplastid protein- expressionssystem |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1242602B1 (de) |
| JP (1) | JP2003513632A (de) |
| AT (1) | ATE386128T1 (de) |
| AU (1) | AU1997901A (de) |
| CA (1) | CA2388151C (de) |
| DE (1) | DE60038045T2 (de) |
| DK (1) | DK1242602T3 (de) |
| ES (1) | ES2301495T3 (de) |
| WO (1) | WO2001032896A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2362383B (en) * | 2000-05-19 | 2003-12-31 | Devgen Nv | Gene expression system |
| DE10214406A1 (de) * | 2002-03-30 | 2003-10-09 | Nutrinova Gmbh | Verfahren und Marker zur einfachen Transformation und Selektion von rekombinanten Protisten |
| US7261887B2 (en) | 2002-11-12 | 2007-08-28 | Rosalind Franklin University Of Medicine And Science | Leishmania as carriers for the delivery of proteins and peptides |
| EP2412382A1 (de) | 2010-07-29 | 2012-02-01 | University Court of the University of Edinburgh | Rekombinanter Trypanosoma theileri-Parasit |
| EP2740791A1 (de) | 2012-12-05 | 2014-06-11 | MicroCoat Biotechnologie GmbH | Verfahren für die rekombinante Herstellung von Pfeilschwanzkrebs-Faktor-C-Protein in Protozoen |
| GB201508025D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Fabry disease gene therapy |
| EP3645732A2 (de) * | 2017-06-30 | 2020-05-06 | Limmatech Biologics AG | Manipulierte und vollfunktionelle massgeschneiderte glycoproteine |
| PL240561B1 (pl) * | 2017-10-09 | 2022-05-02 | Gdanski Univ Medyczny | Wektory DNA zdolne do transformacji i integracji z chromosomem Leishmania tarentolae zawierające gen kodujący butyrylocholinoesterazę BChE |
| AU2021206008A1 (en) * | 2020-01-07 | 2022-07-28 | Limmatech Biologics Ag | Engineered Leishmania cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62282585A (ja) * | 1986-05-31 | 1987-12-08 | Sanraku Inc | ハイブリツドプラスミド |
| JP3172710B2 (ja) * | 1997-07-07 | 2001-06-04 | 理化学研究所 | Ｒｎａポリメラーゼ |
| WO2000032796A2 (en) * | 1998-12-02 | 2000-06-08 | University Of Georgia Research Foundation, Inc. | Kinetoplastid protein expression system |
| US20010010928A1 (en) * | 1999-03-26 | 2001-08-02 | Stephen M. Beverley | Protozoan expression system |
-
2000
- 2000-11-02 WO PCT/EP2000/010794 patent/WO2001032896A1/en not_active Ceased
- 2000-11-02 DK DK00983103T patent/DK1242602T3/da active
- 2000-11-02 JP JP2001535578A patent/JP2003513632A/ja active Pending
- 2000-11-02 DE DE60038045T patent/DE60038045T2/de not_active Expired - Lifetime
- 2000-11-02 EP EP00983103A patent/EP1242602B1/de not_active Expired - Lifetime
- 2000-11-02 CA CA002388151A patent/CA2388151C/en not_active Expired - Fee Related
- 2000-11-02 AU AU19979/01A patent/AU1997901A/en not_active Abandoned
- 2000-11-02 ES ES00983103T patent/ES2301495T3/es not_active Expired - Lifetime
- 2000-11-02 AT AT00983103T patent/ATE386128T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2388151A1 (en) | 2001-05-10 |
| CA2388151C (en) | 2010-01-12 |
| WO2001032896A1 (en) | 2001-05-10 |
| AU1997901A (en) | 2001-05-14 |
| DK1242602T3 (da) | 2008-06-02 |
| JP2003513632A (ja) | 2003-04-15 |
| EP1242602B1 (de) | 2008-02-13 |
| DE60038045D1 (de) | 2008-03-27 |
| EP1242602A1 (de) | 2002-09-25 |
| DE60038045T2 (de) | 2009-02-05 |
| ES2301495T3 (es) | 2008-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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