ATE421994T1 - Genexpressionsmethode - Google Patents

Genexpressionsmethode

Info

Publication number
ATE421994T1
ATE421994T1 AT04806256T AT04806256T ATE421994T1 AT E421994 T1 ATE421994 T1 AT E421994T1 AT 04806256 T AT04806256 T AT 04806256T AT 04806256 T AT04806256 T AT 04806256T AT E421994 T1 ATE421994 T1 AT E421994T1
Authority
AT
Austria
Prior art keywords
protein
gene encoding
host cell
heterologous protein
gene expression
Prior art date
Application number
AT04806256T
Other languages
English (en)
Inventor
Darrell Sleep
Gillian Shuttleworth
Christopher John Arthur Finnis
Original Assignee
Novozymes Biopharma Dk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biopharma Dk As filed Critical Novozymes Biopharma Dk As
Application granted granted Critical
Publication of ATE421994T1 publication Critical patent/ATE421994T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04806256T 2003-12-23 2004-12-23 Genexpressionsmethode ATE421994T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0329681.1A GB0329681D0 (en) 2003-12-23 2003-12-23 Gene expression technique

Publications (1)

Publication Number Publication Date
ATE421994T1 true ATE421994T1 (de) 2009-02-15

Family

ID=30776264

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04806256T ATE421994T1 (de) 2003-12-23 2004-12-23 Genexpressionsmethode

Country Status (15)

Country Link
US (3) US20070275889A1 (de)
EP (2) EP2048236B1 (de)
JP (1) JP5052899B2 (de)
KR (1) KR101262682B1 (de)
CN (2) CN101818121A (de)
AT (1) ATE421994T1 (de)
AU (2) AU2004303601C1 (de)
CA (1) CA2551503A1 (de)
DE (1) DE602004019304D1 (de)
DK (1) DK2048236T3 (de)
ES (1) ES2321948T3 (de)
GB (2) GB0329681D0 (de)
SG (2) SG149003A1 (de)
WO (1) WO2005061718A1 (de)
ZA (1) ZA200605588B (de)

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CN102994541B (zh) * 2012-12-19 2015-04-15 江南大学 一种共表达upr关键基因和下游靶基因增强葡萄糖氧化酶分泌的方法
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CN103436516B (zh) * 2013-08-23 2015-04-22 华南理工大学 利用大肠杆菌原核表达系统生产的小麦蛋白质二硫键异构酶及方法和应用
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CN106661541B (zh) 2014-04-17 2021-09-03 贝林格尔·英格海姆Rcv两合公司 被工程化为过表达辅助蛋白的重组宿主细胞
JP7007261B2 (ja) 2015-08-20 2022-01-24 アルブミディクス リミティド アルブミン変異体及びコンジュゲート
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JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
WO2017190671A1 (zh) * 2016-05-04 2017-11-09 北京普罗吉生物科技发展有限公司 高效表达重组人血清白蛋白工程菌的构建
JP7227159B2 (ja) 2017-01-16 2023-02-21 ナンシャ・バイオロジックス・（ホンコン）・リミテッド 酵母における組換えｉｌ－１１の生産のためのシステムおよび方法
CN106834322B (zh) * 2017-03-14 2020-09-04 中国科学院南海海洋研究所 抗毒素so_1445或其编码基因在提高质粒在宿主细胞中的稳定性中的应用
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CN112391402B (zh) * 2020-11-17 2023-03-28 华中科技大学 一种提高解脂耶氏酵母中目的蛋白表达水平的方法
US20240150807A1 (en) * 2021-03-10 2024-05-09 Sumitomo Pharma Co., Ltd. Method for Producing Cysteine Knot Protein
CN114410496B (zh) * 2022-02-16 2023-10-03 江南大学 一种提高毕赤酵母外源蛋白产量的方法
KR20240094203A (ko) * 2022-12-15 2024-06-25 씨제이제일제당 (주) 트리코더마 속 균주 유래 pdi를 이용하여 재조합 단백질을 생산하는 방법
CN117903295B (zh) * 2024-03-19 2024-05-31 北京国科星联科技有限公司 一种用于分泌表达乳铁蛋白的马克斯克鲁维酵母及其构建方法与应用
CN118460394B (zh) * 2024-07-12 2024-09-24 通化安睿特生物制药股份有限公司 一种用于制备转铁蛋白的工程菌及其应用
CN118895293B (zh) * 2024-10-08 2025-01-28 通化安睿特生物制药股份有限公司 一种产人白蛋白的重组工程菌及其构建方法和应用

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Also Published As

Publication number Publication date
US20120231503A1 (en) 2012-09-13
AU2004303601B2 (en) 2008-03-06
EP2048236A1 (de) 2009-04-15
US20180105818A1 (en) 2018-04-19
KR20070005568A (ko) 2007-01-10
CN101818121A (zh) 2010-09-01
SG182155A1 (en) 2012-07-30
DE602004019304D1 (de) 2009-03-19
DK2048236T3 (da) 2013-05-21
CN1922325B (zh) 2010-06-09
US20070275889A1 (en) 2007-11-29
CA2551503A1 (en) 2005-07-07
WO2005061718A1 (en) 2005-07-07
KR101262682B1 (ko) 2013-05-15
JP5052899B2 (ja) 2012-10-17
GB0614614D0 (en) 2006-08-30
AU2004303601C1 (en) 2009-01-08
JP2007515962A (ja) 2007-06-21
EP1709181A1 (de) 2006-10-11
HK1099938A1 (en) 2007-08-31
EP1709181B1 (de) 2009-01-28
GB0329681D0 (en) 2004-01-28
EP2048236B1 (de) 2013-03-20
AU2008202538A1 (en) 2008-06-26
ES2321948T3 (es) 2009-06-15
SG149003A1 (en) 2009-01-29
CN1922325A (zh) 2007-02-28
ZA200605588B (en) 2009-02-25
GB2424889A (en) 2006-10-11
AU2004303601A1 (en) 2005-07-07

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