ATE38669T1 - Verfahren zur herstellung von 4-hydroxycumarinderivaten. - Google Patents

Verfahren zur herstellung von 4-hydroxycumarinderivaten.

Info

Publication number: ATE38669T1
Authority: AT; Austria
Prior art keywords: chem; group; range; atom; alkyl
Prior art date: 1984-09-26

Application number

AT85201436T

Other languages

English (en)

Inventor

Ian David Entwistle

Peter Boehm

Original Assignee

Shell Int Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-09-26

Filing date

1985-09-10

Publication date

1988-12-15

1985-09-10 Application filed by Shell Int Research filed Critical Shell Int Research

1988-12-15 Application granted granted Critical

1988-12-15 Publication of ATE38669T1 publication Critical patent/ATE38669T1/de

Links

VXIXUWQIVKSKSA-UHFFFAOYSA-N 4-hydroxycoumarin Chemical class C1=CC=CC2=C1OC(=O)C=C2O VXIXUWQIVKSKSA-UHFFFAOYSA-N 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical group COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
238000009835 boiling Methods 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
235000019253 formic acid Nutrition 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000004430 oxygen atom Chemical group O* 0.000 abstract 2
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
KEIFWROAQVVDBN-UHFFFAOYSA-N 1,2-dihydronaphthalene Chemical compound C1=CC=C2C=CCCC2=C1 KEIFWROAQVVDBN-UHFFFAOYSA-N 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
230000002429 anti-coagulating effect Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
150000008282 halocarbons Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
239000003128 rodenticide Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Vibration Dampers (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Control Of Electric Motors In General (AREA)
Electric Propulsion And Braking For Vehicles (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Furan Compounds (AREA)

AT85201436T 1984-09-26 1985-09-10 Verfahren zur herstellung von 4-hydroxycumarinderivaten. ATE38669T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848424317A GB8424317D0 (en)	1984-09-26	1984-09-26	4-hydroxycourmarin derivatives
EP85201436A EP0177080B1 (de)	1984-09-26	1985-09-10	Verfahren zur Herstellung von 4-Hydroxycumarin-Derivaten

Publications (1)

Publication Number	Publication Date
ATE38669T1 true ATE38669T1 (de)	1988-12-15

Family

ID=10567286

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85201436T ATE38669T1 (de)	1984-09-26	1985-09-10	Verfahren zur herstellung von 4-hydroxycumarinderivaten.

Country Status (28)

Country	Link
EP (1)	EP0177080B1 (de)
JP (2)	JPH0794449B2 (de)
KR (1)	KR930009794B1 (de)
AT (1)	ATE38669T1 (de)
AU (1)	AU583533B2 (de)
BR (1)	BR8504673A (de)
CA (1)	CA1263396A (de)
DE (1)	DE3566258D1 (de)
DK (1)	DK162993C (de)
EG (1)	EG17061A (de)
ES (1)	ES8604920A1 (de)
FI (1)	FI86718C (de)
GB (1)	GB8424317D0 (de)
GR (1)	GR852319B (de)
HU (1)	HU196982B (de)
IE (1)	IE58616B1 (de)
IL (1)	IL76490A (de)
IN (1)	IN166513B (de)
MA (1)	MA20532A1 (de)
NO (1)	NO169772C (de)
NZ (1)	NZ213591A (de)
OA (1)	OA08104A (de)
PH (1)	PH22719A (de)
PT (1)	PT81183B (de)
SU (1)	SU1358785A3 (de)
ZA (1)	ZA857326B (de)
ZM (1)	ZM6985A1 (de)
ZW (1)	ZW16985A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8424317D0 (en) *	1984-09-26	1984-10-31	Shell Int Research	4-hydroxycourmarin derivatives
GB9324517D0 (en) *	1993-11-30	1994-01-19	Octel Chem Ltd	Process for the preparation of substituted 4-hydroxycoumarins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1458670A (en) *	1973-05-23	1976-12-15	Ward Blenkinsop & Co Ltd	Anti coagulant 3-tetrahydronaphthyl-4-hydroxy-coumarin deri vatives
EP0098629B1 (de) *	1982-06-14	1987-08-26	Shell Internationale Researchmaatschappij B.V.	Anti-Koagulierungsmittel des 4-Hydroxycumarintyps, deren Zubereitung und diese enthaltende Ratten vernichtende Zusammenstellungen
GB8424317D0 (en) *	1984-09-26	1984-10-31	Shell Int Research	4-hydroxycourmarin derivatives

1984
- 1984-09-26 GB GB848424317A patent/GB8424317D0/en active Pending
1985
- 1985-09-06 CA CA000490120A patent/CA1263396A/en not_active Expired
- 1985-09-10 EP EP85201436A patent/EP0177080B1/de not_active Expired
- 1985-09-10 DE DE8585201436T patent/DE3566258D1/de not_active Expired
- 1985-09-10 AT AT85201436T patent/ATE38669T1/de not_active IP Right Cessation
- 1985-09-20 ZM ZM69/85A patent/ZM6985A1/xx unknown
- 1985-09-20 PH PH32818A patent/PH22719A/en unknown
- 1985-09-23 GR GR852319A patent/GR852319B/el unknown
- 1985-09-24 NZ NZ213591A patent/NZ213591A/en unknown
- 1985-09-24 ES ES547237A patent/ES8604920A1/es not_active Expired
- 1985-09-24 BR BR8504673A patent/BR8504673A/pt not_active IP Right Cessation
- 1985-09-24 IE IE235485A patent/IE58616B1/en not_active IP Right Cessation
- 1985-09-24 MA MA20758A patent/MA20532A1/fr unknown
- 1985-09-24 SU SU853956452A patent/SU1358785A3/ru active
- 1985-09-24 DK DK433385A patent/DK162993C/da not_active IP Right Cessation
- 1985-09-24 FI FI853662A patent/FI86718C/fi not_active IP Right Cessation
- 1985-09-24 KR KR1019850006999A patent/KR930009794B1/ko not_active Expired - Lifetime
- 1985-09-24 NO NO853748A patent/NO169772C/no not_active IP Right Cessation
- 1985-09-24 IN IN776/DEL/85A patent/IN166513B/en unknown
- 1985-09-24 ZW ZW169/85A patent/ZW16985A1/xx unknown
- 1985-09-24 IL IL76490A patent/IL76490A/xx not_active IP Right Cessation
- 1985-09-24 OA OA58684A patent/OA08104A/xx unknown
- 1985-09-24 PT PT81183A patent/PT81183B/pt not_active IP Right Cessation
- 1985-09-24 JP JP60209026A patent/JPH0794449B2/ja not_active Expired - Lifetime
- 1985-09-24 AU AU47822/85A patent/AU583533B2/en not_active Expired
- 1985-09-24 HU HU853592A patent/HU196982B/hu unknown
- 1985-09-24 ZA ZA857326A patent/ZA857326B/xx unknown
- 1985-09-24 EG EG606/85A patent/EG17061A/xx active
1994
- 1994-07-06 JP JP6176207A patent/JP2602783B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0177080A1 (de)	1986-04-09
JPH0794449B2 (ja)	1995-10-11
IE852354L (en)	1986-03-24
IL76490A0 (en)	1986-01-31
ZM6985A1 (en)	1986-01-23
KR930009794B1 (ko)	1993-10-11
FI853662L (fi)	1986-03-27
JP2602783B2 (ja)	1997-04-23
BR8504673A (pt)	1986-07-15
FI853662A0 (fi)	1985-09-24
IL76490A (en)	1989-07-31
AU4782285A (en)	1986-04-10
NO169772C (no)	1992-08-05
ES8604920A1 (es)	1986-03-01
JPH0770103A (ja)	1995-03-14
PT81183A (en)	1985-10-01
NZ213591A (en)	1988-02-29
ZW16985A1 (en)	1985-12-18
DE3566258D1 (en)	1988-12-22
MA20532A1 (fr)	1986-04-01
JPS6185377A (ja)	1986-04-30
ES547237A0 (es)	1986-03-01
GR852319B (de)	1986-01-24
NO169772B (no)	1992-04-27
DK433385A (da)	1986-03-27
EP0177080B1 (de)	1988-11-17
IN166513B (de)	1990-05-19
CA1263396A (en)	1989-11-28
DK433385D0 (da)	1985-09-24
PT81183B (pt)	1987-09-30
KR860002491A (ko)	1986-04-26
OA08104A (en)	1987-03-31
IE58616B1 (en)	1993-10-20
HU196982B (en)	1989-02-28
FI86718C (fi)	1992-10-12
PH22719A (en)	1988-11-28
ZA857326B (en)	1986-07-30
EG17061A (en)	1993-02-28
SU1358785A3 (ru)	1987-12-07
NO853748L (no)	1986-04-01
HUT40097A (en)	1986-11-28
DK162993C (da)	1992-06-01
FI86718B (fi)	1992-06-30
GB8424317D0 (en)	1984-10-31
AU583533B2 (en)	1989-05-04
DK162993B (da)	1992-01-06

Legal Events

Date	Code	Title	Description
1989-03-15	UEP	Publication of translation of european patent specification
2005-12-15	EELA	Cancelled due to lapse of time

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EP0667332A4 (de)	1995-12-27	Verfahren zur herstellung von fluorierten dicarbonylverbindungen.
ATE38669T1 (de)	1988-12-15	Verfahren zur herstellung von 4-hydroxycumarinderivaten.
EP1270563A4 (de)	2003-06-18	Fluorierte oxetan-derivate und verfahren zu deren herstellung
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ATE86257T1 (de)	1993-03-15	Verfahren zur herstellung von thiazolobenzimidazolen und zwischenprodukte.
DE69213680D1 (de)	1996-10-17	Neues Verfahren zur Herstellung von 20-Oxo, 17-Alpha, 21-Dihydroxy Derivaten von Pregnan und neue Zwischenprodukte dafür
JPS56115786A (en)	1981-09-11	3-azaerythrinane derivative