ATE388236T1 - Verfahren zur herstellung des coenzyms q10 - Google Patents

Verfahren zur herstellung des coenzyms q10

Info

Publication number: ATE388236T1
Authority: AT; Austria
Prior art keywords: coenzyme; reduced coenzyme; recovering; present; microbial cells
Prior art date: 2001-12-27

Application number

AT02805906T

Other languages

English (en)

Inventor

Kazuyoshi Yajima

Takahisa Kato

Akihisa Kanda

Shiro Kitamura

Yasuyoshi Ueda

Original Assignee

Kaneka Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-27

Filing date

2002-12-27

Publication date

2008-03-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19189359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE388236(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-27 Application filed by Kaneka Corp filed Critical Kaneka Corp

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE388236T1 publication Critical patent/ATE388236T1/de

Links

ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
QNTNKSLOFHEFPK-UPTCCGCDSA-N ubiquinol-10 Chemical compound COC1=C(O)C(C)=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C(O)=C1OC QNTNKSLOFHEFPK-UPTCCGCDSA-N 0.000 abstract 6
ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 abstract 4
230000000813 microbial effect Effects 0.000 abstract 3
239000005515 coenzyme Substances 0.000 abstract 1
235000017471 coenzyme Q10 Nutrition 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/66—Preparation of oxygen-containing organic compounds containing the quinoid structure

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT02805906T 2001-12-27 2002-12-27 Verfahren zur herstellung des coenzyms q10 ATE388236T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2001398545		2001-12-27

Publications (1)

Publication Number	Publication Date
ATE388236T1 true ATE388236T1 (de)	2008-03-15

Family

ID=19189359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02805906T ATE388236T1 (de)	2001-12-27	2002-12-27	Verfahren zur herstellung des coenzyms q10

Country Status (12)

Country	Link
US (4)	US20050069996A1 (de)
EP (1)	EP1466983B1 (de)
JP (4)	JP4256782B2 (de)
KR (1)	KR100913464B1 (de)
CN (1)	CN100523205C (de)
AT (1)	ATE388236T1 (de)
AU (1)	AU2002357526B2 (de)
CA (1)	CA2471763C (de)
DE (1)	DE60225478C5 (de)
RU (1)	RU2298035C2 (de)
TW (2)	TWI349039B (de)
WO (1)	WO2003056024A1 (de)

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KR101406044B1 (ko) *	2007-06-08	2014-06-12	한국생산기술연구원	감귤박을 탄소원으로 첨가한 배지에서 로도토룰라균의배양을 통한 코엔자임큐텐의 제조방법
WO2009025277A1 (ja) *	2007-08-22	2009-02-26	Kaneka Corporation	還元型補酵素ｑ10の製造方法、ならびに、その安定化方法
CN101307338B (zh) *	2008-07-17	2012-04-25	任雷	还原型辅酶q10的制备方法
BRPI1010576A2 (pt)	2009-05-11	2016-03-15	Berg Biosystems Llc	métodos para tratamento de distúrbios oncológicos usando transferidores epimetabólicos, moléculas intracelulares multidimensionais ou influenciadores ambientais.
WO2011130380A2 (en) *	2010-04-13	2011-10-20	Syracuse University	Coenzyme q10 production using sporidiobolus johnsonii
EP2597156B1 (de) *	2010-07-22	2018-06-27	Kaneka Corporation	Verfahren zur herstellung eines fettlöslichen bioaktiven stoffes
US9655849B2 (en)	2011-03-18	2017-05-23	Particle Dynamics International, Llc	Solid particulate compositions comprising coenzyme Q10
EP2694463B8 (de)	2011-04-04	2019-10-09	Berg LLC	Behandlung von tumoren im zentralnervensystem mit coenzym q10
CN102557912B (zh) *	2011-12-31	2015-01-07	内蒙古金达威药业有限公司	一种辅酶q10提取液的皂化方法
US9360454B2 (en) *	2012-03-02	2016-06-07	Berg Llc	Methods and kits for detection of coenzyme Q10
SG11201508272YA (en)	2013-04-08	2015-11-27	Berg Llc	Treatment of cancer using coenzyme q10 combination therapies
JP6595478B2 (ja)	2013-09-04	2019-10-23	バーグエルエルシー	コエンザイムｑ１０の連続注入によるがんの治療方法
CN103819326B (zh) *	2013-12-11	2016-08-17	湖南科源生物制品有限公司	一种从微生物中分离纯化辅酶q10的方法
JP2016208909A (ja) *	2015-05-08	2016-12-15	株式会社カネカ	脂溶性生理活性物質の製造方法
CN107709567B (zh) *	2015-06-23	2021-11-02	株式会社钟化	还原型辅酶q10的制造方法
WO2017087576A1 (en)	2015-11-16	2017-05-26	Berg Llc	Methods of treatment of temozolomide-resistant glioma using coenzyme q10
CN105886562A (zh) *	2016-05-31	2016-08-24	兰州天和生物催化技术有限公司	微生物发酵法制备辅酶q10的方法
EP3480317A4 (de) *	2016-07-01	2020-01-22	Kaneka Corporation	Verfahren zur herstellung von koenzym q10
CN108048496B (zh) *	2017-12-25	2020-11-10	浙江新和成股份有限公司	氧化型辅酶q10的发酵生产方法、及由其制备而得的高含量氧化型辅酶q10
US10774350B2 (en)	2017-12-25	2020-09-15	Zhejiang Nhu Company Ltd.	Method for fermentative production of oxidized coenzyme Q10
WO2019189290A1 (ja) *	2018-03-28	2019-10-03	株式会社カネカ	補酵素ｑ１０の製造方法
JP7539831B2 (ja) *	2018-04-27	2024-08-26	株式会社カネカ	補酵素ｑ１０の製造方法
CN108997153B (zh) *	2018-07-25	2021-02-02	中国人民大学	从光合细菌中逐级提取多种高价值物质的方法
CN109055417B (zh)	2018-08-28	2020-07-07	浙江新和成股份有限公司	一种重组微生物、其制备方法及其在生产辅酶q10中的应用
CN109762757B (zh) *	2018-12-25	2020-01-07	神舟生物科技有限责任公司	一种高产辅酶q10类球红细菌及其诱变选育和应用
US11471426B2 (en)	2019-10-16	2022-10-18	American River Nutrition, Llc	Compositions comprising quinone and/or quinol and methods of preparations and use thereof
CN112755589B (zh) *	2021-02-23	2022-04-15	山东泰和水处理科技股份有限公司	精制辅酶q10的萃取方法及装置
JP2023133924A (ja) *	2022-03-14	2023-09-27	株式会社リコー	余剰粉体除去用洗浄液、立体造形物の製造方法、及び造形液と洗浄液のセット
CN115584357B (zh) *	2022-11-02	2023-10-20	广东润和生物科技有限公司	一种辅酶q10的发酵提取方法
CN117586110B (zh) *	2023-11-22	2025-07-25	湖南祥民制药有限公司	一种辅酶q10的分离提纯方法

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JP3742602B2 (ja) *	2001-05-09	2006-02-08	株式会社カネカ	還元型補酵素ｑの安定な溶液
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US20040197886A1 (en) *	2001-07-13	2004-10-07	Takahiro Ueda	Method of crystallizing reduced coenzyme Q10 from aqueous solution
TWI237019B (en) *	2001-07-13	2005-08-01	Kaneka Corp	Method of producing reduced coenzyme Q10
TWI310029B (de) *	2001-07-13	2009-05-21	Kaneka Corp
TWI235146B (en) *	2001-07-16	2005-07-01	Kaneka Corp	Method of stabilizing reduced coenzyme q10 and method of acidic crystallization
JP3822479B2 (ja) *	2001-10-10	2006-09-20	株式会社カネカ	還元型補酵素ｑ水溶液の安定化組成
TWI329510B (en) *	2001-10-10	2010-09-01	Kaneka Corp	Method of stabilizing reduced coenzyme q10
TWI349039B (en) *	2001-12-27	2011-09-21	Kaneka Corp	Processes for producing coenzyme q10
JP3781118B2 (ja)	2003-03-03	2006-05-31	セイコーエプソン株式会社	配線基板の製造方法

2002
- 2002-12-26 TW TW097132867A patent/TWI349039B/zh not_active IP Right Cessation
- 2002-12-26 TW TW091137404A patent/TWI305547B/zh not_active IP Right Cessation
- 2002-12-27 KR KR1020047010068A patent/KR100913464B1/ko not_active Expired - Fee Related
- 2002-12-27 US US10/500,249 patent/US20050069996A1/en not_active Abandoned
- 2002-12-27 RU RU2004122912/13A patent/RU2298035C2/ru not_active IP Right Cessation
- 2002-12-27 WO PCT/JP2002/013766 patent/WO2003056024A1/ja not_active Ceased
- 2002-12-27 JP JP2003556541A patent/JP4256782B2/ja not_active Expired - Fee Related
- 2002-12-27 CA CA2471763A patent/CA2471763C/en not_active Expired - Lifetime
- 2002-12-27 AT AT02805906T patent/ATE388236T1/de not_active IP Right Cessation
- 2002-12-27 CN CNB028262417A patent/CN100523205C/zh not_active Expired - Lifetime
- 2002-12-27 DE DE60225478.7T patent/DE60225478C5/de not_active Expired - Lifetime
- 2002-12-27 EP EP02805906A patent/EP1466983B1/de not_active Expired - Lifetime
- 2002-12-27 AU AU2002357526A patent/AU2002357526B2/en not_active Expired
2007
- 2007-10-31 US US11/981,181 patent/US7910340B2/en not_active Expired - Lifetime
2008
- 2008-05-07 JP JP2008121453A patent/JP5074287B2/ja not_active Expired - Fee Related
2011
- 2011-02-03 US US13/020,500 patent/US9315839B2/en not_active Expired - Fee Related
2012
- 2012-04-17 JP JP2012094126A patent/JP5788831B2/ja not_active Expired - Fee Related
2014
- 2014-06-18 JP JP2014125185A patent/JP2014166191A/ja active Pending
2016
- 2016-03-21 US US15/076,025 patent/US9926580B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP5074287B2 (ja)	2012-11-14
US9315839B2 (en)	2016-04-19
KR100913464B1 (ko)	2009-08-25
US7910340B2 (en)	2011-03-22
JP2012157360A (ja)	2012-08-23
AU2002357526A1 (en)	2003-07-15
AU2002357526B2 (en)	2007-10-18
TW200900507A (en)	2009-01-01
RU2004122912A (ru)	2005-06-27
CN1608136A (zh)	2005-04-20
TWI305547B (en)	2009-01-21
CN100523205C (zh)	2009-08-05
JP5788831B2 (ja)	2015-10-07
RU2298035C2 (ru)	2007-04-27
US20110136191A1 (en)	2011-06-09
JP2014166191A (ja)	2014-09-11
EP1466983B1 (de)	2008-03-05
EP1466983A1 (de)	2004-10-13
CA2471763C (en)	2012-02-14
DE60225478D1 (de)	2008-04-17
KR20040076266A (ko)	2004-08-31
TW200301306A (en)	2003-07-01
US9926580B2 (en)	2018-03-27
JPWO2003056024A1 (ja)	2005-05-12
US20080171373A1 (en)	2008-07-17
US20160304915A1 (en)	2016-10-20
WO2003056024A1 (fr)	2003-07-10
TWI349039B (en)	2011-09-21
EP1466983A4 (de)	2005-11-09
DE60225478C5 (de)	2015-09-17
JP2008253271A (ja)	2008-10-23
CA2471763A1 (en)	2003-07-10
JP4256782B2 (ja)	2009-04-22
US20050069996A1 (en)	2005-03-31
DE60225478T2 (de)	2009-02-26

Legal Events

Date	Code	Title	Description
2008-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE388236T1 (de)	2008-03-15	Verfahren zur herstellung des coenzyms q10
DE60127343D1 (de)	2007-05-03	Kontinuierliches Verfahren zur Herstellung von Wasserstoffperoxid in organischen Lösungsmitteln, wobei die Konzentration an Wasserstoff kleiner als 4,5>%Vol. und die Konzentration von Sauerstoff kleiner als 21,5 %Vol. beträgt.
DE60035418D1 (de)	2007-08-16	Wasserstoff-durchlässige metallmembran und verfahren zu ihrer herstellung
ATE293014T1 (de)	2005-04-15	Katalysator zum abbau von distickstoffoxid sowie methode zur durchführung von verfahren, welche die bildung von distickstoffoxid beinhalten
DE69200983D1 (de)	1995-02-09	Verfahren zur Herstellung von Wasserstoffsuperoxyd.
EP0686427A4 (de)	1996-11-20	Katalysator zur verarbeitung von abwasser, methode zu dessen herstellung und methode zur verarbeitung von abwasser unter anwendung des katalysators
DE69803076D1 (de)	2002-01-31	Verfahren zum einsatzhärten
PL1621258T3 (pl)	2011-12-30	Sposób wytwarzania cienkich folii organicznych
AU1408900A (en)	2000-06-19	Method for synthesizing cdna
DE69329500D1 (de)	2000-11-02	Ein verfahren zur herstellung von immunosuppressiva und eine neuartige mikrobielle spezies, die dabei eingesetzt wird
ATE399771T1 (de)	2008-07-15	Verfahren zur herstellung von 1,2-epoxy-3- chlorpropan
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