ATE388236T1 - Verfahren zur herstellung des coenzyms q10 - Google Patents

Verfahren zur herstellung des coenzyms q10

Info

Publication number
ATE388236T1
ATE388236T1 AT02805906T AT02805906T ATE388236T1 AT E388236 T1 ATE388236 T1 AT E388236T1 AT 02805906 T AT02805906 T AT 02805906T AT 02805906 T AT02805906 T AT 02805906T AT E388236 T1 ATE388236 T1 AT E388236T1
Authority
AT
Austria
Prior art keywords
coenzyme
reduced coenzyme
recovering
present
microbial cells
Prior art date
Application number
AT02805906T
Other languages
English (en)
Inventor
Kazuyoshi Yajima
Takahisa Kato
Akihisa Kanda
Shiro Kitamura
Yasuyoshi Ueda
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19189359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE388236(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kaneka Corp filed Critical Kaneka Corp
Application granted granted Critical
Publication of ATE388236T1 publication Critical patent/ATE388236T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/66Preparation of oxygen-containing organic compounds containing the quinoid structure

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02805906T 2001-12-27 2002-12-27 Verfahren zur herstellung des coenzyms q10 ATE388236T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001398545 2001-12-27

Publications (1)

Publication Number Publication Date
ATE388236T1 true ATE388236T1 (de) 2008-03-15

Family

ID=19189359

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02805906T ATE388236T1 (de) 2001-12-27 2002-12-27 Verfahren zur herstellung des coenzyms q10

Country Status (12)

Country Link
US (4) US20050069996A1 (de)
EP (1) EP1466983B1 (de)
JP (4) JP4256782B2 (de)
KR (1) KR100913464B1 (de)
CN (1) CN100523205C (de)
AT (1) ATE388236T1 (de)
AU (1) AU2002357526B2 (de)
CA (1) CA2471763C (de)
DE (1) DE60225478C5 (de)
RU (1) RU2298035C2 (de)
TW (2) TWI305547B (de)
WO (1) WO2003056024A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI305547B (en) 2001-12-27 2009-01-21 Kaneka Corp Processes for producing coenzyme q10
TW200302055A (en) * 2002-01-18 2003-08-01 Kaneka Corp Ubiquinol-enriched fat-containing foods
JP4426832B2 (ja) 2002-12-03 2010-03-03 株式会社分子生理化学研究所 コエンザイムq−10及びその2電子還元体の分析方法
WO2006092449A2 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
WO2007126086A1 (ja) * 2006-04-28 2007-11-08 Kaneka Corporation 還元型補酵素q10の精製方法
KR101406044B1 (ko) * 2007-06-08 2014-06-12 한국생산기술연구원 감귤박을 탄소원으로 첨가한 배지에서 로도토룰라균의배양을 통한 코엔자임큐텐의 제조방법
US20110123505A1 (en) * 2007-08-22 2011-05-26 Kaneka Corporation Method of producing reduced coenzyme q10 and method of stabilizing the same
CN101307338B (zh) * 2008-07-17 2012-04-25 任雷 还原型辅酶q10的制备方法
CN102481271A (zh) 2009-05-11 2012-05-30 博格生物系统有限责任公司 利用表观代谢转变剂、多维细胞内分子或环境影响剂治疗代谢障碍的方法
US20110269196A1 (en) * 2010-04-13 2011-11-03 Syracuse University Coenzyme q10 production using sporidiobolus johnsonii
WO2012011589A1 (ja) * 2010-07-22 2012-01-26 株式会社カネカ 脂溶性生理活性物質の製造方法
US9655849B2 (en) 2011-03-18 2017-05-23 Particle Dynamics International, Llc Solid particulate compositions comprising coenzyme Q10
CA2832324C (en) 2011-04-04 2022-03-15 Berg Llc Methods of treating central nervous system tumors
CN102557912B (zh) * 2011-12-31 2015-01-07 内蒙古金达威药业有限公司 一种辅酶q10提取液的皂化方法
EP3578990A1 (de) * 2012-03-02 2019-12-11 Berg LLC Verfahren und kits zum nachweis des coenzyms q10
NZ713868A (en) 2013-04-08 2021-12-24 Berg Llc Treatment of cancer using coenzyme q10 combination therapies
KR102370843B1 (ko) 2013-09-04 2022-03-04 버그 엘엘씨 코엔자임 q10의 연속주입에 의한 암치료 방법
CN103819326B (zh) * 2013-12-11 2016-08-17 湖南科源生物制品有限公司 一种从微生物中分离纯化辅酶q10的方法
JP2016208909A (ja) * 2015-05-08 2016-12-15 株式会社カネカ 脂溶性生理活性物質の製造方法
JP6757724B2 (ja) 2015-06-23 2020-09-23 株式会社カネカ 還元型補酵素q10の製造方法
WO2017087576A1 (en) 2015-11-16 2017-05-26 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10
CN105886562A (zh) * 2016-05-31 2016-08-24 兰州天和生物催化技术有限公司 微生物发酵法制备辅酶q10的方法
CN109415744B (zh) * 2016-07-01 2023-04-28 株式会社钟化 辅酶q10的制造方法
US10774350B2 (en) 2017-12-25 2020-09-15 Zhejiang Nhu Company Ltd. Method for fermentative production of oxidized coenzyme Q10
CN108048496B (zh) * 2017-12-25 2020-11-10 浙江新和成股份有限公司 氧化型辅酶q10的发酵生产方法、及由其制备而得的高含量氧化型辅酶q10
JP7421471B2 (ja) * 2018-03-28 2024-01-24 株式会社カネカ 補酵素q10の製造方法
WO2019208676A1 (ja) * 2018-04-27 2019-10-31 株式会社カネカ 補酵素q10の製造方法
CN108997153B (zh) * 2018-07-25 2021-02-02 中国人民大学 从光合细菌中逐级提取多种高价值物质的方法
CN109055417B (zh) 2018-08-28 2020-07-07 浙江新和成股份有限公司 一种重组微生物、其制备方法及其在生产辅酶q10中的应用
CN109762757B (zh) * 2018-12-25 2020-01-07 神舟生物科技有限责任公司 一种高产辅酶q10类球红细菌及其诱变选育和应用
US11471426B2 (en) 2019-10-16 2022-10-18 American River Nutrition, Llc Compositions comprising quinone and/or quinol and methods of preparations and use thereof
CN112755589B (zh) * 2021-02-23 2022-04-15 山东泰和水处理科技股份有限公司 精制辅酶q10的萃取方法及装置
JP2023133924A (ja) 2022-03-14 2023-09-27 株式会社リコー 余剰粉体除去用洗浄液、立体造形物の製造方法、及び造形液と洗浄液のセット
CN115584357B (zh) * 2022-11-02 2023-10-20 广东润和生物科技有限公司 一种辅酶q10的发酵提取方法
CN117586110B (zh) * 2023-11-22 2025-07-25 湖南祥民制药有限公司 一种辅酶q10的分离提纯方法
EP4717761A2 (de) 2024-09-30 2026-04-01 Kod-Bio Lda Verfahren zur extraktion von biopigmenten aus mikrobiellen kulturen

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JPS5452790A (en) * 1977-10-04 1979-04-25 Kanegafuchi Chem Ind Co Ltd Preparation of coenzyme q
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JPS5857155B2 (ja) 1978-03-07 1983-12-19 協和醗酵工業株式会社 発酵法によるコエンチ−ムq↓1↓0の製造法
JPS54126792A (en) * 1978-03-20 1979-10-02 Hiroshi Aida Production of coenzyme q10
JPS5527A (en) * 1978-05-25 1980-01-05 Kanegafuchi Chem Ind Co Ltd Microbiological preparation of coenzyme q10
JPS5528A (en) * 1978-05-29 1980-01-05 Hiroshi Aida Preparation of coenzyme q9
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JPS593197B2 (ja) 1978-09-25 1984-01-23 十條製紙株式会社 補酵素q↓1↓0の製造法
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JPS63102691A (ja) 1987-09-11 1988-05-07 Nisshin Flour Milling Co Ltd 補酵素q↓1↓0の製造法
JPH088836B2 (ja) 1991-10-31 1996-01-31 社団法人長野県農村工業研究所 酵素により特性を改変した澱粉粒の利用方法
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JP3889481B2 (ja) 1996-08-16 2007-03-07 株式会社カネカ 医薬組成物
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ATE399209T1 (de) * 2000-11-20 2008-07-15 Kaneka Corp Verfahren zur herstellung von coenzym q 10
JP2002191367A (ja) 2000-12-27 2002-07-09 Kanegafuchi Chem Ind Co Ltd コエンザイムq10の製造法
JP2002345469A (ja) * 2001-04-25 2002-12-03 Kanegafuchi Chem Ind Co Ltd コエンザイムq10の製造法
JP3742602B2 (ja) * 2001-05-09 2006-02-08 株式会社カネカ 還元型補酵素qの安定な溶液
TWI310029B (de) * 2001-07-13 2009-05-21 Kaneka Corp
CN1266102C (zh) * 2001-07-13 2006-07-26 钟渊化学工业株式会社 还原型辅酶q10在水溶液中结晶的方法
TW200604159A (en) * 2001-07-13 2006-02-01 Kaneka Corp Method of producing reduced coenzyme Q10 as oily product
TWI237018B (en) * 2001-07-13 2005-08-01 Kaneka Corp Method of producing reduced coenzyme Q10 crystals
TWI237019B (en) * 2001-07-13 2005-08-01 Kaneka Corp Method of producing reduced coenzyme Q10
TWI235146B (en) * 2001-07-16 2005-07-01 Kaneka Corp Method of stabilizing reduced coenzyme q10 and method of acidic crystallization
TWI329510B (en) * 2001-10-10 2010-09-01 Kaneka Corp Method of stabilizing reduced coenzyme q10
JP3822479B2 (ja) * 2001-10-10 2006-09-20 株式会社カネカ 還元型補酵素q水溶液の安定化組成
TWI305547B (en) * 2001-12-27 2009-01-21 Kaneka Corp Processes for producing coenzyme q10
JP3781118B2 (ja) 2003-03-03 2006-05-31 セイコーエプソン株式会社 配線基板の製造方法

Also Published As

Publication number Publication date
RU2298035C2 (ru) 2007-04-27
CA2471763A1 (en) 2003-07-10
EP1466983A1 (de) 2004-10-13
DE60225478D1 (de) 2008-04-17
DE60225478T2 (de) 2009-02-26
JP4256782B2 (ja) 2009-04-22
KR100913464B1 (ko) 2009-08-25
AU2002357526B2 (en) 2007-10-18
JP2014166191A (ja) 2014-09-11
US20160304915A1 (en) 2016-10-20
US9315839B2 (en) 2016-04-19
US9926580B2 (en) 2018-03-27
US7910340B2 (en) 2011-03-22
DE60225478C5 (de) 2015-09-17
TW200900507A (en) 2009-01-01
JP5788831B2 (ja) 2015-10-07
TWI349039B (en) 2011-09-21
CA2471763C (en) 2012-02-14
TW200301306A (en) 2003-07-01
WO2003056024A1 (fr) 2003-07-10
US20080171373A1 (en) 2008-07-17
JP2008253271A (ja) 2008-10-23
CN1608136A (zh) 2005-04-20
CN100523205C (zh) 2009-08-05
EP1466983A4 (de) 2005-11-09
RU2004122912A (ru) 2005-06-27
KR20040076266A (ko) 2004-08-31
JP5074287B2 (ja) 2012-11-14
US20050069996A1 (en) 2005-03-31
US20110136191A1 (en) 2011-06-09
TWI305547B (en) 2009-01-21
EP1466983B1 (de) 2008-03-05
JPWO2003056024A1 (ja) 2005-05-12
JP2012157360A (ja) 2012-08-23
AU2002357526A1 (en) 2003-07-15

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