ATE389009T1 - Vorrichtung und verfahren für kontinuierliche zellkultur - Google Patents

Vorrichtung und verfahren für kontinuierliche zellkultur

Info

Publication number
ATE389009T1
ATE389009T1 AT02749038T AT02749038T ATE389009T1 AT E389009 T1 ATE389009 T1 AT E389009T1 AT 02749038 T AT02749038 T AT 02749038T AT 02749038 T AT02749038 T AT 02749038T AT E389009 T1 ATE389009 T1 AT E389009T1
Authority
AT
Austria
Prior art keywords
sample
path
cell culture
continuous cell
detector
Prior art date
Application number
AT02749038T
Other languages
English (en)
Inventor
Brian Ellison
Colin Gibson
Norman Grant
Gerard Hyland
David Lloyd
John Magee
David Pooley
William Stewart
Original Assignee
Univ Cardiff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cardiff filed Critical Univ Cardiff
Application granted granted Critical
Publication of ATE389009T1 publication Critical patent/ATE389009T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N22/00Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Electromagnetism (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT02749038T 2001-07-19 2002-07-19 Vorrichtung und verfahren für kontinuierliche zellkultur ATE389009T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0117715.3A GB0117715D0 (en) 2001-07-19 2001-07-19 Microwave biochemical analysis

Publications (1)

Publication Number Publication Date
ATE389009T1 true ATE389009T1 (de) 2008-03-15

Family

ID=9918876

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02749038T ATE389009T1 (de) 2001-07-19 2002-07-19 Vorrichtung und verfahren für kontinuierliche zellkultur

Country Status (11)

Country Link
US (2) US20040175294A1 (de)
EP (2) EP1892287A3 (de)
JP (2) JP4260621B2 (de)
AT (1) ATE389009T1 (de)
AU (1) AU2002319453B9 (de)
BR (1) BR0211249A (de)
CA (1) CA2454293A1 (de)
DE (1) DE60225559T2 (de)
GB (1) GB0117715D0 (de)
NZ (1) NZ530665A (de)
WO (1) WO2003008532A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6380751B2 (en) 1992-06-11 2002-04-30 Cascade Microtech, Inc. Wafer probe station having environment control enclosure
US5345170A (en) 1992-06-11 1994-09-06 Cascade Microtech, Inc. Wafer probe station having integrated guarding, Kelvin connection and shielding systems
US6232789B1 (en) 1997-05-28 2001-05-15 Cascade Microtech, Inc. Probe holder for low current measurements
US5561377A (en) 1995-04-14 1996-10-01 Cascade Microtech, Inc. System for evaluating probing networks
US5914613A (en) 1996-08-08 1999-06-22 Cascade Microtech, Inc. Membrane probing system with local contact scrub
US6002263A (en) 1997-06-06 1999-12-14 Cascade Microtech, Inc. Probe station having inner and outer shielding
US6256882B1 (en) 1998-07-14 2001-07-10 Cascade Microtech, Inc. Membrane probing system
US6578264B1 (en) 1999-06-04 2003-06-17 Cascade Microtech, Inc. Method for constructing a membrane probe using a depression
US6445202B1 (en) 1999-06-30 2002-09-03 Cascade Microtech, Inc. Probe station thermal chuck with shielding for capacitive current
US6838890B2 (en) 2000-02-25 2005-01-04 Cascade Microtech, Inc. Membrane probing system
US6965226B2 (en) 2000-09-05 2005-11-15 Cascade Microtech, Inc. Chuck for holding a device under test
US6914423B2 (en) 2000-09-05 2005-07-05 Cascade Microtech, Inc. Probe station
DE10143173A1 (de) 2000-12-04 2002-06-06 Cascade Microtech Inc Wafersonde
WO2003052435A1 (en) 2001-08-21 2003-06-26 Cascade Microtech, Inc. Membrane probing system
US6777964B2 (en) 2002-01-25 2004-08-17 Cascade Microtech, Inc. Probe station
JP2005527823A (ja) 2002-05-23 2005-09-15 カスケード マイクロテック インコーポレイテッド デバイスのテスト用プローブ
US6847219B1 (en) 2002-11-08 2005-01-25 Cascade Microtech, Inc. Probe station with low noise characteristics
US6724205B1 (en) 2002-11-13 2004-04-20 Cascade Microtech, Inc. Probe for combined signals
US7250779B2 (en) 2002-11-25 2007-07-31 Cascade Microtech, Inc. Probe station with low inductance path
US6861856B2 (en) 2002-12-13 2005-03-01 Cascade Microtech, Inc. Guarded tub enclosure
GB0307352D0 (en) 2003-03-29 2003-05-07 Qinetiq Ltd Improvements in and relating to the analysis of compounds
US20120221256A1 (en) * 2003-03-29 2012-08-30 Midas Mediscience Functional characterization of biological samples
US7221172B2 (en) 2003-05-06 2007-05-22 Cascade Microtech, Inc. Switched suspended conductor and connection
US7057404B2 (en) 2003-05-23 2006-06-06 Sharp Laboratories Of America, Inc. Shielded probe for testing a device under test
US7492172B2 (en) 2003-05-23 2009-02-17 Cascade Microtech, Inc. Chuck for holding a device under test
US7250626B2 (en) 2003-10-22 2007-07-31 Cascade Microtech, Inc. Probe testing structure
DE202004021093U1 (de) 2003-12-24 2006-09-28 Cascade Microtech, Inc., Beaverton Aktiver Halbleiterscheibenmessfühler
US7187188B2 (en) 2003-12-24 2007-03-06 Cascade Microtech, Inc. Chuck with integrated wafer support
DE102004010217A1 (de) * 2004-02-27 2005-09-15 Carl Zeiss Jena Gmbh Anordnung und Verfahren zur spektroskopischen Bestimmung der Bestandteile und Konzentrationen pumpfähiger organischer Verbindungen
JP2008502167A (ja) 2004-06-07 2008-01-24 カスケード マイクロテック インコーポレイテッド 熱光学チャック
US7330041B2 (en) 2004-06-14 2008-02-12 Cascade Microtech, Inc. Localizing a temperature of a device for testing
US7368927B2 (en) 2004-07-07 2008-05-06 Cascade Microtech, Inc. Probe head having a membrane suspended probe
KR20070058522A (ko) 2004-09-13 2007-06-08 캐스케이드 마이크로테크 인코포레이티드 양측 프루빙 구조
JP2006174828A (ja) * 2004-11-29 2006-07-06 Olympus Corp 生体試料培養観察システム、インキュベータボックス、供給手段、および培養容器
US7535247B2 (en) 2005-01-31 2009-05-19 Cascade Microtech, Inc. Interface for testing semiconductors
US7656172B2 (en) 2005-01-31 2010-02-02 Cascade Microtech, Inc. System for testing semiconductors
RU2007135288A (ru) * 2005-02-23 2009-03-27 Алфред Майкл ВИГВЕРИ (AU) Система наблюдения для обнаружения микроорганизмов
GB0504284D0 (en) 2005-03-02 2005-04-06 Boc Group Plc Conveyor system
US20060219941A1 (en) * 2005-03-29 2006-10-05 Clifford Edward T Bubble type radiation detectors having automated read-out
ITMI20050693A1 (it) * 2005-04-19 2006-10-20 C N R Consiglio Naz Delle Ricerche Apparecchiatura per la coltura di cellule eucariotiche e-o procariotiche
GB0510709D0 (en) 2005-05-26 2005-06-29 Cymtox Ltd Water monitoring system
US7449899B2 (en) 2005-06-08 2008-11-11 Cascade Microtech, Inc. Probe for high frequency signals
JP5080459B2 (ja) 2005-06-13 2012-11-21 カスケード マイクロテック インコーポレイテッド 広帯域能動/受動差動信号プローブ
US7525102B1 (en) * 2005-10-03 2009-04-28 Sparta, Inc. Agent detection in the presence of background clutter
DE102006022307A1 (de) * 2006-05-11 2007-11-15 Respironics Novametrix, LLC, Wallingford Einwegbioreaktor mit Sensoranordnung
DE202007018733U1 (de) 2006-06-09 2009-03-26 Cascade Microtech, Inc., Beaverton Messfühler für differentielle Signale mit integrierter Symmetrieschaltung
US7403028B2 (en) 2006-06-12 2008-07-22 Cascade Microtech, Inc. Test structure and probe for differential signals
US7723999B2 (en) 2006-06-12 2010-05-25 Cascade Microtech, Inc. Calibration structures for differential signal probing
US7764072B2 (en) 2006-06-12 2010-07-27 Cascade Microtech, Inc. Differential signal probing system
US7443186B2 (en) 2006-06-12 2008-10-28 Cascade Microtech, Inc. On-wafer test structures for differential signals
US20080012578A1 (en) * 2006-07-14 2008-01-17 Cascade Microtech, Inc. System for detecting molecular structure and events
US8014959B2 (en) * 2007-05-07 2011-09-06 Sparta, Inc. Population of background suppression lists from limited data in agent detection systems
US7876114B2 (en) 2007-08-08 2011-01-25 Cascade Microtech, Inc. Differential waveguide probe
US9952296B2 (en) * 2007-12-21 2018-04-24 Koninklijke Philip N.V. Magnetic resonance safety monitoring systems and methods
US7888957B2 (en) 2008-10-06 2011-02-15 Cascade Microtech, Inc. Probing apparatus with impedance optimized interface
NL2002196C2 (en) * 2008-11-11 2010-05-17 Avantium Int Bv SAMPLE ANALYZES APPARATUS AND A METHOD OR ANALYZING A SAMPLE.
WO2010059247A2 (en) 2008-11-21 2010-05-27 Cascade Microtech, Inc. Replaceable coupon for a probing apparatus
US8319503B2 (en) 2008-11-24 2012-11-27 Cascade Microtech, Inc. Test apparatus for measuring a characteristic of a device under test
EP2420113A4 (de) * 2009-04-14 2014-04-02 Rf Thummim Technologies Inc Verfahren und vorrichtung zur erregung von resonanzen in molekülen
CA2830480A1 (en) 2010-03-17 2011-09-22 Rf Thummim Technologies, Inc. Method and apparatus for electromagnetically producing a disturbance in a medium with simultaneous resonance of acoustic waves created by the disturbance
CN102305800B (zh) * 2011-07-29 2013-05-08 华南理工大学 基于超宽带的易燃液体检测方法
CN102519898B (zh) * 2011-12-29 2013-07-10 上海智城分析仪器制造有限公司 单光源检测摇床发酵液体的装置
JP6227355B2 (ja) * 2013-09-27 2017-11-08 スタンレー電気株式会社 水素製造装置
TWI512285B (zh) * 2014-03-18 2015-12-11 Univ Kun Shan A method for measuring the number of cells and measuring the number of cells with a precision counting function
JP6228282B1 (ja) * 2016-09-27 2017-11-08 株式会社協和医療器 菌培養検査装置及び菌培養検査方法
US11455298B2 (en) 2019-02-06 2022-09-27 Parsons Corporation Goal-directed semantic search
US11922252B1 (en) * 2020-01-14 2024-03-05 Oceanit Laboratories, Inc. Metamaterials technology for ore tracking
CN111349559B (zh) * 2020-03-13 2022-10-14 中国人民解放军军事科学院军事医学研究院 一种小型宽带微波生物效应照射装置
JP7637477B2 (ja) * 2020-05-14 2025-02-28 株式会社日立ハイテク 細胞検出装置及び細胞検出方法
WO2022053953A1 (en) * 2020-09-09 2022-03-17 Know Labs, Inc. Systems and methods for analyzing in vitro flowing fluids and determining variability in a state of a medium

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327180A (en) * 1979-09-14 1982-04-27 Board Of Governors, Wayne State Univ. Method and apparatus for electromagnetic radiation of biological material
US4337648A (en) * 1980-11-03 1982-07-06 Jodon Engineering Associates, Inc. Dual probe coupler
FI831936A0 (fi) * 1983-05-30 1983-05-30 Labsystems Oy Anordning foer maetning av fluorescens, turbiditet, luminescens eller absorption
US5089385A (en) * 1987-06-01 1992-02-18 The United States Of America As Represented By The Secretary Of The Air Force Method of culturing cells in a flow-through cell cultivation system
US5028541A (en) * 1987-06-01 1991-07-02 The United States Of America As Represented By The Secretary Of The Air Force Flow-through cell cultivation system
US4948975A (en) * 1988-09-08 1990-08-14 The United States Of America As Represented By The Secretary Of The Air Force Quantitative luminescence imaging system
JPH02119772A (ja) * 1988-10-29 1990-05-07 Shimadzu Corp 細胞培養装置
US5150061A (en) * 1989-05-23 1992-09-22 Institut Francais Du Petrole Method and device for measuring the qualities of a multiphase fluid
US5144224A (en) * 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer
US5644244A (en) * 1991-06-21 1997-07-01 Texaco Inc. Method for analyzing a petroleum stream
GB9119382D0 (en) * 1991-09-11 1991-10-23 Knight Scient Ltd Apparatus for monitoring liquids
DE4211362C2 (de) * 1992-04-04 1995-04-20 Berthold Lab Prof Dr Vorrichtung zur Bestimmung von Materialparametern durch Mikrowellenmessungen
US5759847A (en) * 1995-07-14 1998-06-02 Difco Laboratories System and apparatus for automatically transferring media
GB2303916B (en) * 1995-07-29 1999-03-03 Siemens Plc Improvements in or relating to aqueous sample testing apparatus
US6122042A (en) * 1997-02-07 2000-09-19 Wunderman; Irwin Devices and methods for optically identifying characteristics of material objects
FR2771508B1 (fr) * 1997-11-26 2000-11-03 Pasteur Institut Appareil et procede de mesure de proprietes optiques par retroaction
ES2286750T3 (es) * 1998-05-01 2007-12-01 Gen-Probe Incorporated Dispositivo para agitar el contenido liquido de un contenedor.
AU8023500A (en) * 1999-10-13 2001-04-23 Mds Sciex System and method for detecting and identifying molecular events in a test sample

Also Published As

Publication number Publication date
EP1892287A3 (de) 2008-04-09
US20090269836A1 (en) 2009-10-29
DE60225559D1 (de) 2008-04-24
BR0211249A (pt) 2004-07-27
EP1409637B1 (de) 2008-03-12
AU2002319453B9 (en) 2009-07-30
DE60225559T2 (de) 2009-04-02
JP2009136286A (ja) 2009-06-25
JP2004535811A (ja) 2004-12-02
AU2002319453B2 (en) 2008-04-24
EP1409637A1 (de) 2004-04-21
EP1892287A2 (de) 2008-02-27
GB0117715D0 (en) 2001-09-12
WO2003008532A1 (en) 2003-01-30
NZ530665A (en) 2006-10-27
JP4260621B2 (ja) 2009-04-30
US20040175294A1 (en) 2004-09-09
CA2454293A1 (en) 2003-01-30

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