ATE389719T1 - Behandlungsverfahren mit wisp-polypeptiden - Google Patents

Behandlungsverfahren mit wisp-polypeptiden

Info

Publication number: ATE389719T1
Authority: AT; Austria
Prior art keywords: administration; cartilage; treatment; injury; repair
Prior art date: 2000-10-16

Application number

AT01987803T

Other languages

English (en)

Inventor

Luc Desnoyer

Ellen Filvaroff

Diane Pennica

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-16

Filing date

2001-10-12

Publication date

2008-04-15

2001-10-12 Application filed by Genentech Inc filed Critical Genentech Inc

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE389719T1 publication Critical patent/ATE389719T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 4
229920001184 polypeptide Polymers 0.000 title abstract 4
102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
210000000845 cartilage Anatomy 0.000 abstract 5
208000027418 Wounds and injury Diseases 0.000 abstract 3
230000006378 damage Effects 0.000 abstract 3
230000003412 degenerative effect Effects 0.000 abstract 3
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
208000014674 injury Diseases 0.000 abstract 3
239000005557 antagonist Substances 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
206010003246 arthritis Diseases 0.000 abstract 1
230000015556 catabolic process Effects 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
210000001612 chondrocyte Anatomy 0.000 abstract 1
239000003102 growth factor Substances 0.000 abstract 1
238000001356 surgical procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT01987803T 2000-10-16 2001-10-12 Behandlungsverfahren mit wisp-polypeptiden ATE389719T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US24122200P	2000-10-16	2000-10-16

Publications (1)

Publication Number	Publication Date
ATE389719T1 true ATE389719T1 (de)	2008-04-15

Family

ID=22909763

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT01987803T ATE389719T1 (de)	2000-10-16	2001-10-12	Behandlungsverfahren mit wisp-polypeptiden
AT10000199T ATE544855T1 (de)	2000-10-16	2001-10-12	Wisp polypeptide, und deren therapeutische anwendungen
AT08001040T ATE456655T1 (de)	2000-10-16	2001-10-12	Behandlungsverfahren unter verwendung von wisp- polypeptiden

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT10000199T ATE544855T1 (de)	2000-10-16	2001-10-12	Wisp polypeptide, und deren therapeutische anwendungen
AT08001040T ATE456655T1 (de)	2000-10-16	2001-10-12	Behandlungsverfahren unter verwendung von wisp- polypeptiden

Country Status (10)

Country	Link
US (2)	US7687460B2 (de)
EP (3)	EP2180053B1 (de)
JP (1)	JP4202128B2 (de)
AT (3)	ATE389719T1 (de)
AU (2)	AU2437702A (de)
CA (1)	CA2425145C (de)
DE (2)	DE60141236D1 (de)
ES (3)	ES2338492T3 (de)
IL (3)	IL155279A0 (de)
WO (1)	WO2002033085A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4202128B2 (ja) *	2000-10-16	2008-12-24	ジェネンテック・インコーポレーテッド	Ｗｉｓｐポリペプチドを用いる治療方法
WO2005025603A2 (en) *	2003-09-11	2005-03-24	Genentech, Inc.	Methods of using wisp antagonists
SE0401069D0 (sv) *	2004-04-26	2004-04-26	Anamar Medical Ab	Use of Compounds for the Treatment of Diseases and Conditions
AU2007261530B2 (en) *	2006-06-20	2014-02-06	Genzyme Corporation	Serum-free media and their uses for chondrocyte expansion
AU2008246125B2 (en)	2007-04-26	2013-01-24	Genera Istrazivanja D.O.O.	Blood biomarkers for bone fracture and cartilage injury
JP5985152B2 (ja)	2008-01-18	2016-09-06	バーナムインスティテュートフォーメディカルリサーチ	Ｒｇｄ１ペプチドの内部移行に関係する方法および組成物
CN102869384B (zh) *	2009-06-22	2016-01-13	伯纳姆医学研究所	使用带有c-端元件的肽和蛋白质的方法和组合物
AU2010273570B2 (en) *	2009-07-14	2014-07-03	Novartis Ag	Mesenchymal stem cell differentiation
US20140037659A1 (en) *	2011-01-31	2014-02-06	Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.	Snx9 as a novel biomarker for chronic inflammation and associated immunosuppresion and a new regulator of t cell receptor expression and function
KR102148303B1 (ko)	2012-02-11	2020-08-26	제넨테크, 인크.	R-스폰딘 전위 및 그의 사용 방법
JO3564B1 (ar)	2013-03-08	2020-07-05	Novartis Ag	ببتيدات وتركيبات لعلاج ضرر المفاصل
US9301971B2 (en)	2013-03-08	2016-04-05	Novartis Ag	Peptides and compositions for treatment of joint damage
JP2019501943A (ja) *	2016-01-14	2019-01-24	スパイナルサイト，エルエルシー	軟骨細胞または軟骨型細胞を再生するための細胞混成物
CA3025960A1 (en) *	2016-06-02	2017-12-07	Nestec S.A.	Methods for treating sarcopenia and muscle injury
AR116566A1 (es)	2018-10-03	2021-05-19	Novartis Ag	Administración sostenida de polipéptidos similares a la angiopoyetina 3
EP3711772A1 (de) *	2019-03-20	2020-09-23	Oslo Universitetssykehus HF	Rekombinante proteine und fusionsproteine
KR102167443B1 (ko) *	2019-03-25	2020-10-19	주식회사 카티프라임	체외 골관절염 모델 및 이를 이용한 골관절염 치료제 스크리닝 방법
CN111700881B (zh) *	2020-07-02	2021-05-18	四川大学	Wnt蛋白＼ZIF-8纳米复合体、其制备方法及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5364839A (en)	1990-06-18	1994-11-15	Genetics Institute, Inc.	Osteoinductive pharmaceutical formulations
US5206023A (en)	1991-01-31	1993-04-27	Robert F. Shaw	Method and compositions for the treatment and repair of defects or lesions in cartilage
US5408040A (en)	1991-08-30	1995-04-18	University Of South Florida	Connective tissue growth factor(CTGF)
CA2177061A1 (en)	1993-12-22	1995-06-29	Gideon A. Rodan	Dna encoding the wnt-x growth factor
US5444047A (en)	1994-06-16	1995-08-22	Dipasquale; Gene	Treatment of arthritic and post-surgical orthopedic conditions with Insulin-like Growth Factor-I
WO2000053753A2 (en) *	1999-03-08	2000-09-14	Genentech, Inc.	Promotion or inhibition of angiogenesis and cardiovascularization
AU7610396A (en)	1996-11-08	1998-06-03	Human Genome Sciences, Inc.	Connective tissue growth factor-3
AU7980598A (en) *	1997-06-19	1999-01-04	Incyte Pharmaceuticals, Inc.	Polynucleotides encoding a growth factor-like protein (as amended)
US20020192209A1 (en) *	1997-09-17	2002-12-19	Genentech, Inc.	Methods and compositions for inhibiting neoplastic cell growth
EP2014770A3 (de) *	1997-10-29	2009-02-18	Genentech, Inc.	WNT-1-induziertes sekretiertes Polypeptid WISP-2
WO1999062927A1 (en) *	1998-06-05	1999-12-09	Human Genome Sciences, Inc.	Connective tissue growth factor-4
KR100342045B1 (ko) *	1999-04-16	2002-06-27	김순택	2차전지
WO2001007085A1 (en) *	1999-07-23	2001-02-01	Case Western Reserve University	Novel methods and reagents useful in the treatment of osteoarthritis
US20020063763A1 (en) *	2000-11-29	2002-05-30	Mantell David Allen	Apparatus and method for removing air bubbles from an ink jet printhead
GB9930768D0 (en) *	1999-12-29	2000-02-16	Pfizer Ltd	Composition
US6812339B1 (en) *	2000-09-08	2004-11-02	Applera Corporation	Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
JP4202128B2 (ja) *	2000-10-16	2008-12-24	ジェネンテック・インコーポレーテッド	Ｗｉｓｐポリペプチドを用いる治療方法

2001
- 2001-10-12 JP JP2002536453A patent/JP4202128B2/ja not_active Expired - Fee Related
- 2001-10-12 ES ES08001040T patent/ES2338492T3/es not_active Expired - Lifetime
- 2001-10-12 EP EP10000199A patent/EP2180053B1/de not_active Expired - Lifetime
- 2001-10-12 AT AT01987803T patent/ATE389719T1/de active
- 2001-10-12 AU AU2437702A patent/AU2437702A/xx active Pending
- 2001-10-12 ES ES01987803T patent/ES2304401T3/es not_active Expired - Lifetime
- 2001-10-12 DE DE60141236T patent/DE60141236D1/de not_active Expired - Lifetime
- 2001-10-12 IL IL15527901A patent/IL155279A0/xx unknown
- 2001-10-12 US US10/399,093 patent/US7687460B2/en not_active Expired - Fee Related
- 2001-10-12 AT AT10000199T patent/ATE544855T1/de active
- 2001-10-12 EP EP08001040A patent/EP1927659B1/de not_active Expired - Lifetime
- 2001-10-12 AU AU2002224377A patent/AU2002224377B2/en not_active Ceased
- 2001-10-12 DE DE60133301T patent/DE60133301T2/de not_active Expired - Lifetime
- 2001-10-12 EP EP01987803A patent/EP1326980B1/de not_active Expired - Lifetime
- 2001-10-12 AT AT08001040T patent/ATE456655T1/de active
- 2001-10-12 ES ES10000199T patent/ES2381935T3/es not_active Expired - Lifetime
- 2001-10-12 WO PCT/US2001/032142 patent/WO2002033085A2/en not_active Ceased
- 2001-10-12 CA CA2425145A patent/CA2425145C/en not_active Expired - Fee Related
2003
- 2003-04-08 IL IL155279A patent/IL155279A/en not_active IP Right Cessation
2009
- 2009-08-07 US US12/537,888 patent/US8138152B2/en not_active Expired - Fee Related
- 2009-08-19 IL IL200484A patent/IL200484A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO2002033085A2 (en)	2002-04-25
DE60133301T2 (de)	2009-05-14
ATE456655T1 (de)	2010-02-15
IL155279A0 (en)	2003-11-23
AU2002224377B2 (en)	2007-07-19
EP2180053A2 (de)	2010-04-28
EP2180053B1 (de)	2012-02-08
CA2425145C (en)	2011-08-30
EP2180053A3 (de)	2010-11-10
ES2304401T3 (es)	2008-10-16
US20050054563A1 (en)	2005-03-10
EP1326980A2 (de)	2003-07-16
IL200484A (en)	2012-05-31
JP2004534720A (ja)	2004-11-18
US7687460B2 (en)	2010-03-30
IL200484A0 (en)	2010-04-29
ATE544855T1 (de)	2012-02-15
DE60133301D1 (de)	2008-04-30
US8138152B2 (en)	2012-03-20
AU2002224377B8 (en)	2002-04-29
JP4202128B2 (ja)	2008-12-24
EP1927659B1 (de)	2010-01-27
DE60141236D1 (de)	2010-03-18
WO2002033085A9 (en)	2002-07-25
IL155279A (en)	2011-05-31
EP1927659A1 (de)	2008-06-04
EP1326980B1 (de)	2008-03-19
CA2425145A1 (en)	2002-04-25
US20100093628A1 (en)	2010-04-15
ES2338492T3 (es)	2010-05-07
ES2381935T3 (es)	2012-06-01
AU2437702A (en)	2002-04-29
WO2002033085A3 (en)	2003-04-17

Legal Events

Date

Code

Title

Description

2008-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1326980

Country of ref document: EP

Publication	Publication Date	Title
IL200484A0 (en)	2010-04-29	Use of wisp polypeptides wisp for the preparation of medicaments
IL151408A0 (en)	2003-04-10	Use of insulin for the treatment of cartilagenous disorders
ATE265529T1 (de)	2004-05-15	Bmp-10 zusammensetzungen
DK0968012T3 (da)	2006-12-27	Osteogene indretninger og fremgangsmåder til anvendelse deraf til reparation af knogler
DE69729125D1 (de)	2004-06-17	Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese
ATE258984T1 (de)	2004-02-15	Bmp-11 zusammensetzungen
ES2182902T3 (es)	2003-03-16	Sistema de reparacion de superficies de articulaciones.
ATE390142T1 (de)	2008-04-15	Synergistische zusammensetzung zur behandlung von diabetes mellitus
PT807633E (pt)	2003-02-28	Novas pirimidin-4-onas substituidas em 2,3, e fundidas com heteroarilo em (5,6)
EA200400734A1 (ru)	2004-12-30	Способ и композиция для потенциирования действия опиатного анальгетика
DE69821793D1 (de)	2004-03-25	Neuronale verwendungen des bmp-11
DE60140960D1 (de)	2010-02-11	Verwendung von serp-1 in kombination mit einem immunosuppressor zur behandlung von arthritis
EP1499190A4 (de)	2005-06-15	Verfahren zur behandlung von lebererkrankungen und leberschäden mit wachstumshormon und foxm1b
IT1293305B1 (it)	1999-02-16	Sali di acidi difosfonici e loro impiego farmacologico nel trattamento dell'osteoporosi
DE69808475D1 (de)	2002-11-07	Aminosäurederivate zur behandlung von schlaganfall
DK0918455T3 (da)	2003-08-04	Anvendelse af galanin til reparation af nerveskader
DE69941134D1 (de)	2009-08-27	Verwendung von R (+)- g(a)-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol zur Behandlung von Schlafstörungen
BR9709007A (pt)	2000-01-04	Uso de azaspirano substituìdo no tratamento da asma.