ATE456655T1 - Behandlungsverfahren unter verwendung von wisp- polypeptiden - Google Patents
Behandlungsverfahren unter verwendung von wisp- polypeptidenInfo
- Publication number
- ATE456655T1 ATE456655T1 AT08001040T AT08001040T ATE456655T1 AT E456655 T1 ATE456655 T1 AT E456655T1 AT 08001040 T AT08001040 T AT 08001040T AT 08001040 T AT08001040 T AT 08001040T AT E456655 T1 ATE456655 T1 AT E456655T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- cartilage
- treatment
- injury
- repair
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 210000000845 cartilage Anatomy 0.000 abstract 5
- 208000027418 Wounds and injury Diseases 0.000 abstract 3
- 230000006378 damage Effects 0.000 abstract 3
- 230000003412 degenerative effect Effects 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000014674 injury Diseases 0.000 abstract 3
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000001612 chondrocyte Anatomy 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24122200P | 2000-10-16 | 2000-10-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE456655T1 true ATE456655T1 (de) | 2010-02-15 |
Family
ID=22909763
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10000199T ATE544855T1 (de) | 2000-10-16 | 2001-10-12 | Wisp polypeptide, und deren therapeutische anwendungen |
| AT08001040T ATE456655T1 (de) | 2000-10-16 | 2001-10-12 | Behandlungsverfahren unter verwendung von wisp- polypeptiden |
| AT01987803T ATE389719T1 (de) | 2000-10-16 | 2001-10-12 | Behandlungsverfahren mit wisp-polypeptiden |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10000199T ATE544855T1 (de) | 2000-10-16 | 2001-10-12 | Wisp polypeptide, und deren therapeutische anwendungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01987803T ATE389719T1 (de) | 2000-10-16 | 2001-10-12 | Behandlungsverfahren mit wisp-polypeptiden |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7687460B2 (de) |
| EP (3) | EP1927659B1 (de) |
| JP (1) | JP4202128B2 (de) |
| AT (3) | ATE544855T1 (de) |
| AU (2) | AU2437702A (de) |
| CA (1) | CA2425145C (de) |
| DE (2) | DE60133301T2 (de) |
| ES (3) | ES2304401T3 (de) |
| IL (3) | IL155279A0 (de) |
| WO (1) | WO2002033085A2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2304401T3 (es) * | 2000-10-16 | 2008-10-16 | Genentech, Inc. | Metodos de tratamiento que utilizan polipeptidos wisp. |
| US20060292150A1 (en) * | 2003-09-11 | 2006-12-28 | Luc Desnoyers | Methods of using wisp antagonists |
| SE0401069D0 (sv) * | 2004-04-26 | 2004-04-26 | Anamar Medical Ab | Use of Compounds for the Treatment of Diseases and Conditions |
| AU2007261530B2 (en) * | 2006-06-20 | 2014-02-06 | Genzyme Corporation | Serum-free media and their uses for chondrocyte expansion |
| EP2147311A4 (de) * | 2007-04-26 | 2010-08-11 | Genera Istrazivanja D O O | Blut-biomarker für knochenbruch und knorpelverletzung |
| AU2009234338B2 (en) | 2008-01-18 | 2014-07-24 | Burnham Institute For Medical Research | Methods and compositions related to internalizing RGD peptides |
| BRPI1015424B1 (pt) | 2009-06-22 | 2022-01-18 | Burnham Institute For Medical Research | Composição compreendendo um elemento cendr e uma co-composição e composição para uso no reforço da internalização, penetração, ou ambas, de uma co-composição |
| PL2453921T3 (pl) | 2009-07-14 | 2015-11-30 | Scripps Research Inst | Różnicowanie mezenchymalnych komórek macierzystych |
| EP2671079B1 (de) * | 2011-01-31 | 2018-12-26 | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. | Snx9 als neue biomarker für chronische entzündungen und zugehörige immunosuppression sowie ein neuer regulator der t-zell-rezeptorexpression und funktion |
| MX366804B (es) | 2012-02-11 | 2019-07-25 | Genentech Inc | Translocaciones de la r-espondina y sus metodos de uso. |
| US9301971B2 (en) | 2013-03-08 | 2016-04-05 | Novartis Ag | Peptides and compositions for treatment of joint damage |
| UY35368A (es) | 2013-03-08 | 2014-10-31 | Irm Llc | Péptidos y composiciones para el tratamiento de daño articular |
| AU2017207445B2 (en) * | 2016-01-14 | 2023-12-07 | Spinalcyte, Llc | Cellular blend for the regeneration of chondrocytes or cartilage type cells |
| JP2019527193A (ja) * | 2016-06-02 | 2019-09-26 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | サルコペニア及び筋損傷を治療する方法 |
| AR116566A1 (es) | 2018-10-03 | 2021-05-19 | Novartis Ag | Administración sostenida de polipéptidos similares a la angiopoyetina 3 |
| EP3711772A1 (de) * | 2019-03-20 | 2020-09-23 | Oslo Universitetssykehus HF | Rekombinante proteine und fusionsproteine |
| KR102167443B1 (ko) * | 2019-03-25 | 2020-10-19 | 주식회사 카티프라임 | 체외 골관절염 모델 및 이를 이용한 골관절염 치료제 스크리닝 방법 |
| CN111700881B (zh) * | 2020-07-02 | 2021-05-18 | 四川大学 | Wnt蛋白\ZIF-8纳米复合体、其制备方法及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364839A (en) | 1990-06-18 | 1994-11-15 | Genetics Institute, Inc. | Osteoinductive pharmaceutical formulations |
| US5206023A (en) | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
| US5408040A (en) * | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
| WO1995017416A1 (en) | 1993-12-22 | 1995-06-29 | Merck & Co., Inc. | Dna encoding the wnt-x growth factor |
| US5444047A (en) * | 1994-06-16 | 1995-08-22 | Dipasquale; Gene | Treatment of arthritic and post-surgical orthopedic conditions with Insulin-like Growth Factor-I |
| ES2246056T3 (es) | 1996-11-08 | 2006-02-01 | Human Genome Sciences, Inc. | Factor 3 de crecimiento de tejido conjuntivo. |
| CA2294564A1 (en) * | 1997-06-19 | 1998-12-23 | Incyte Pharmaceuticals, Inc. | Polynucleotides encoding a growth factor-like protein |
| US20020192209A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| IL135704A (en) * | 1997-10-29 | 2008-04-13 | Genentech Inc | Method of diagnosing neoplastic cell growth by detection of the wnt-1 induced secreted polypeptide wisp-1 |
| AU4411499A (en) * | 1998-06-05 | 1999-12-20 | Human Genome Sciences, Inc. | Connective tissue growth factor-4 |
| AU2600800A (en) * | 1999-03-08 | 2000-09-28 | Genentech Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| KR100342045B1 (ko) * | 1999-04-16 | 2002-06-27 | 김순택 | 2차전지 |
| WO2001007085A1 (en) | 1999-07-23 | 2001-02-01 | Case Western Reserve University | Novel methods and reagents useful in the treatment of osteoarthritis |
| GB9930768D0 (en) | 1999-12-29 | 2000-02-16 | Pfizer Ltd | Composition |
| US20020063763A1 (en) * | 2000-11-29 | 2002-05-30 | Mantell David Allen | Apparatus and method for removing air bubbles from an ink jet printhead |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| ES2304401T3 (es) * | 2000-10-16 | 2008-10-16 | Genentech, Inc. | Metodos de tratamiento que utilizan polipeptidos wisp. |
-
2001
- 2001-10-12 ES ES01987803T patent/ES2304401T3/es not_active Expired - Lifetime
- 2001-10-12 AT AT10000199T patent/ATE544855T1/de active
- 2001-10-12 IL IL15527901A patent/IL155279A0/xx unknown
- 2001-10-12 AU AU2437702A patent/AU2437702A/xx active Pending
- 2001-10-12 ES ES10000199T patent/ES2381935T3/es not_active Expired - Lifetime
- 2001-10-12 DE DE60133301T patent/DE60133301T2/de not_active Expired - Lifetime
- 2001-10-12 DE DE60141236T patent/DE60141236D1/de not_active Expired - Lifetime
- 2001-10-12 AT AT08001040T patent/ATE456655T1/de active
- 2001-10-12 AT AT01987803T patent/ATE389719T1/de active
- 2001-10-12 EP EP08001040A patent/EP1927659B1/de not_active Expired - Lifetime
- 2001-10-12 EP EP10000199A patent/EP2180053B1/de not_active Expired - Lifetime
- 2001-10-12 EP EP01987803A patent/EP1326980B1/de not_active Expired - Lifetime
- 2001-10-12 US US10/399,093 patent/US7687460B2/en not_active Expired - Fee Related
- 2001-10-12 WO PCT/US2001/032142 patent/WO2002033085A2/en not_active Ceased
- 2001-10-12 CA CA2425145A patent/CA2425145C/en not_active Expired - Fee Related
- 2001-10-12 JP JP2002536453A patent/JP4202128B2/ja not_active Expired - Fee Related
- 2001-10-12 AU AU2002224377A patent/AU2002224377B2/en not_active Ceased
- 2001-10-12 ES ES08001040T patent/ES2338492T3/es not_active Expired - Lifetime
-
2003
- 2003-04-08 IL IL155279A patent/IL155279A/en not_active IP Right Cessation
-
2009
- 2009-08-07 US US12/537,888 patent/US8138152B2/en not_active Expired - Fee Related
- 2009-08-19 IL IL200484A patent/IL200484A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002224377B8 (en) | 2002-04-29 |
| EP2180053A2 (de) | 2010-04-28 |
| AU2437702A (en) | 2002-04-29 |
| EP2180053B1 (de) | 2012-02-08 |
| IL155279A (en) | 2011-05-31 |
| ATE389719T1 (de) | 2008-04-15 |
| CA2425145A1 (en) | 2002-04-25 |
| AU2002224377B2 (en) | 2007-07-19 |
| WO2002033085A3 (en) | 2003-04-17 |
| ES2338492T3 (es) | 2010-05-07 |
| US8138152B2 (en) | 2012-03-20 |
| US20100093628A1 (en) | 2010-04-15 |
| CA2425145C (en) | 2011-08-30 |
| IL200484A0 (en) | 2010-04-29 |
| WO2002033085A9 (en) | 2002-07-25 |
| ES2381935T3 (es) | 2012-06-01 |
| EP1927659A1 (de) | 2008-06-04 |
| US20050054563A1 (en) | 2005-03-10 |
| DE60133301D1 (de) | 2008-04-30 |
| DE60141236D1 (de) | 2010-03-18 |
| JP4202128B2 (ja) | 2008-12-24 |
| EP1326980B1 (de) | 2008-03-19 |
| EP2180053A3 (de) | 2010-11-10 |
| DE60133301T2 (de) | 2009-05-14 |
| ES2304401T3 (es) | 2008-10-16 |
| ATE544855T1 (de) | 2012-02-15 |
| IL155279A0 (en) | 2003-11-23 |
| US7687460B2 (en) | 2010-03-30 |
| JP2004534720A (ja) | 2004-11-18 |
| EP1326980A2 (de) | 2003-07-16 |
| EP1927659B1 (de) | 2010-01-27 |
| IL200484A (en) | 2012-05-31 |
| WO2002033085A2 (en) | 2002-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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