ATE390403T1 - Verfahren zur herstellung eines optisch aktiven 3,5-dihydroxycarbonsäurederivats - Google Patents
Verfahren zur herstellung eines optisch aktiven 3,5-dihydroxycarbonsäurederivatsInfo
- Publication number
- ATE390403T1 ATE390403T1 AT02777941T AT02777941T ATE390403T1 AT E390403 T1 ATE390403 T1 AT E390403T1 AT 02777941 T AT02777941 T AT 02777941T AT 02777941 T AT02777941 T AT 02777941T AT E390403 T1 ATE390403 T1 AT E390403T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- acid derivative
- producing
- dihydroxycarbonic
- complex
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- RUSJDZRTPDUURW-UHFFFAOYSA-N 3,5-dihydroxyhexanoic acid Chemical class CC(O)CC(O)CC(O)=O RUSJDZRTPDUURW-UHFFFAOYSA-N 0.000 abstract 2
- ZQPJZYKENZNLOW-UHFFFAOYSA-N 5-hydroxy-3-oxohexanoic acid Chemical class CC(O)CC(=O)CC(O)=O ZQPJZYKENZNLOW-UHFFFAOYSA-N 0.000 abstract 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000012327 Ruthenium complex Substances 0.000 abstract 1
- MUALRAIOVNYAIW-UHFFFAOYSA-N binap Chemical compound C1=CC=CC=C1P(C=1C(=C2C=CC=CC2=CC=1)C=1C2=CC=CC=C2C=CC=1P(C=1C=CC=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 MUALRAIOVNYAIW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
- C07C67/29—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
- Oscillators With Electromechanical Resonators (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001327019 | 2001-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE390403T1 true ATE390403T1 (de) | 2008-04-15 |
Family
ID=19143304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02777941T ATE390403T1 (de) | 2001-10-24 | 2002-10-24 | Verfahren zur herstellung eines optisch aktiven 3,5-dihydroxycarbonsäurederivats |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6998495B2 (de) |
| EP (1) | EP1439162B1 (de) |
| JP (1) | JP4195384B2 (de) |
| KR (1) | KR20040058230A (de) |
| AT (1) | ATE390403T1 (de) |
| CA (1) | CA2464446A1 (de) |
| DE (1) | DE60225825T2 (de) |
| WO (1) | WO2003040082A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5232374B2 (ja) * | 2006-09-29 | 2013-07-10 | 関東化学株式会社 | ２位に置換基を有する光学活性キヌクリジノール類の製造方法 |
| CN103483195A (zh) * | 2013-09-10 | 2014-01-01 | 黄冈华阳药业有限公司 | (3r,5s)-6-氯-3,5-二羟基己酸叔丁酯的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62265293A (ja) * | 1986-05-13 | 1987-11-18 | Takasago Corp | ルテニウム−ホスフイン錯体 |
| JPH0678277B2 (ja) * | 1988-02-19 | 1994-10-05 | 高砂香料工業株式会社 | 光学活性アルコールおよびその誘導体の製造方法 |
| IE894067L (en) * | 1988-12-21 | 1990-06-21 | Ackley Michael | Process for the production of 3,5,6-trihydroxyhexanoic acid¹derivative |
| DE69009237T2 (de) * | 1989-02-27 | 1994-12-01 | Takasago Perfumery Co Ltd | Verfahren zur Herstellung von optisch aktiven Estern der 6-t-Butoxy-3,5-dihydroxyhexansäure. |
| FR2670206B1 (fr) | 1990-12-11 | 1993-01-22 | Rhone Poulenc Sante | Procede de preparation de derives de l'acide dihydroxy-3,5 pentanouique. |
| FR2670211B1 (fr) | 1990-12-11 | 1993-01-22 | Rhone Poulenc Sante | Procede de preparation de derives de l'acide dihydroxy-3,5 oxo-6 hexanouique. |
| JP3149265B2 (ja) | 1992-05-12 | 2001-03-26 | 鐘淵化学工業株式会社 | 光学活性な３，５−ジヒドロキシ脂肪酸エステル誘導体の製造法 |
| FR2693190B1 (fr) * | 1992-07-02 | 1994-09-23 | Elf Aquitaine | Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO. |
| US5508435A (en) * | 1992-07-29 | 1996-04-16 | Merck & Co., Inc. | Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides |
-
2002
- 2002-10-24 US US10/492,507 patent/US6998495B2/en not_active Expired - Fee Related
- 2002-10-24 DE DE60225825T patent/DE60225825T2/de not_active Expired - Lifetime
- 2002-10-24 JP JP2003542130A patent/JP4195384B2/ja not_active Expired - Fee Related
- 2002-10-24 EP EP02777941A patent/EP1439162B1/de not_active Expired - Lifetime
- 2002-10-24 KR KR10-2004-7006030A patent/KR20040058230A/ko not_active Withdrawn
- 2002-10-24 WO PCT/JP2002/011036 patent/WO2003040082A1/ja not_active Ceased
- 2002-10-24 AT AT02777941T patent/ATE390403T1/de not_active IP Right Cessation
- 2002-10-24 CA CA002464446A patent/CA2464446A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1439162B1 (de) | 2008-03-26 |
| CA2464446A1 (en) | 2003-05-15 |
| KR20040058230A (ko) | 2004-07-03 |
| JPWO2003040082A1 (ja) | 2005-03-03 |
| WO2003040082A1 (en) | 2003-05-15 |
| EP1439162A1 (de) | 2004-07-21 |
| US6998495B2 (en) | 2006-02-14 |
| JP4195384B2 (ja) | 2008-12-10 |
| DE60225825T2 (de) | 2009-04-16 |
| EP1439162A4 (de) | 2006-03-08 |
| DE60225825D1 (en) | 2008-05-08 |
| US20040254392A1 (en) | 2004-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |