ATE390633T1 - Reagens zum nachweis eines morbus-alzheimer- risikofaktors, nachweiskit dafür und verfahren zum nachweis eines morbus-alzheimer-risikofaktors unter verwendung davon - Google Patents
Reagens zum nachweis eines morbus-alzheimer- risikofaktors, nachweiskit dafür und verfahren zum nachweis eines morbus-alzheimer-risikofaktors unter verwendung davonInfo
- Publication number
- ATE390633T1 ATE390633T1 AT02800770T AT02800770T ATE390633T1 AT E390633 T1 ATE390633 T1 AT E390633T1 AT 02800770 T AT02800770 T AT 02800770T AT 02800770 T AT02800770 T AT 02800770T AT E390633 T1 ATE390633 T1 AT E390633T1
- Authority
- AT
- Austria
- Prior art keywords
- alzheimer
- detecting
- risk factor
- disease risk
- apolipoprotein
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108010060159 Apolipoprotein E4 Proteins 0.000 abstract 3
- 108010060219 Apolipoprotein E2 Proteins 0.000 abstract 1
- 108010060215 Apolipoprotein E3 Proteins 0.000 abstract 1
- 102000008128 Apolipoprotein E3 Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001308465 | 2001-10-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE390633T1 true ATE390633T1 (de) | 2008-04-15 |
Family
ID=19127771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02800770T ATE390633T1 (de) | 2001-10-04 | 2002-10-04 | Reagens zum nachweis eines morbus-alzheimer- risikofaktors, nachweiskit dafür und verfahren zum nachweis eines morbus-alzheimer-risikofaktors unter verwendung davon |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050266501A1 (de) |
| EP (1) | EP1434053B1 (de) |
| JP (1) | JP4153873B2 (de) |
| AT (1) | ATE390633T1 (de) |
| DE (1) | DE60225821T2 (de) |
| WO (1) | WO2003031971A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| GB2408508A (en) | 2003-11-28 | 2005-06-01 | Astrazeneca Ab | Apolipoprotein antibodies |
| US7612179B2 (en) | 2003-11-28 | 2009-11-03 | Astrazeneca Ab | antibodies binding to a C-terminal fragment of apoliopoprotein E |
| US9335331B2 (en) * | 2005-04-11 | 2016-05-10 | Cornell Research Foundation, Inc. | Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject |
| PT1976877E (pt) | 2005-11-30 | 2014-04-29 | Abbvie Inc | Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações |
| BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
| WO2007092380A2 (en) * | 2006-02-06 | 2007-08-16 | Berkeley Heartlab, Inc. | Apolipoprotein e genotyping and accompanying internet-based health management system |
| JP2009531712A (ja) * | 2006-03-23 | 2009-09-03 | デ グスマン ブレイヤー、エメリタ | アポリポタンパク質フィンガープリント技術 |
| DE102006056337A1 (de) * | 2006-11-29 | 2008-06-05 | B.R.A.H.M.S Ag | In vitro Verfahren zur Diagnose und Frühdiagnose von neurodegenerativen Erkrankungen |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (de) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Verfahren zur behandlung von amyloidosen |
| GB0921447D0 (en) * | 2009-12-04 | 2010-01-20 | Randox Lab Ltd | Assay |
| EP2558494B1 (de) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta-bindende proteine |
| CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
| EP2847218A4 (de) * | 2012-05-08 | 2015-12-30 | Univ Ramot | Apoe4-antikörper zur behandlung neurodegenerativer erkrankungen |
| GB2511525A (en) * | 2013-03-05 | 2014-09-10 | Randox Teoranta | Methods and Compositions for the Diagnosis of Alzheimer's Disease |
| KR101509641B1 (ko) * | 2013-05-08 | 2015-04-06 | 경북대학교 산학협력단 | 아포지단백질 m을 포함하는 알츠하이머 질환 진단용 마커 조성물 |
| EP3163303A1 (de) * | 2015-11-02 | 2017-05-03 | Biocross, S.L. | Verfahren für apolipoproteinnachweis |
| EP3309550A1 (de) * | 2016-10-12 | 2018-04-18 | sphingotec GmbH | Verfahren zum nachweis von apolipoprotein e4 |
| CN117607456A (zh) * | 2017-07-31 | 2024-02-27 | 奎斯特诊断投资有限公司 | 通过质谱法进行的载脂蛋白e同种型检测 |
| CN112362876B (zh) * | 2020-08-06 | 2023-12-15 | 武汉天德生物科技有限公司 | 一种检测早期老年痴呆症的胶体金试纸条及其制备方法 |
| CN112540179B (zh) * | 2020-08-06 | 2023-07-07 | 武汉天德生物科技有限公司 | 一种测试ApoE4蛋白含量的ELISA试剂盒 |
| CN112540178B (zh) * | 2020-08-06 | 2023-12-19 | 武汉天德生物科技有限公司 | 一种检测早期老年痴呆症的免疫组化试剂盒及其使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US19821A (en) * | 1858-03-30 | Improvement in cotton-presses | ||
| US5472858A (en) * | 1991-06-04 | 1995-12-05 | Wisconsin Alumni Research Foundation | Production of recombinant proteins in insect larvae |
| WO1994009155A1 (en) * | 1992-10-13 | 1994-04-28 | Duke University | Methods of detecting alzheimer's disease |
| US5773220A (en) * | 1995-07-28 | 1998-06-30 | University Of Pittsburgh | Determination of Alzheimer's disease risk using apolipoprotein E and .alpha. |
| JP3397066B2 (ja) * | 1996-12-27 | 2003-04-14 | 富士レビオ株式会社 | 免疫学的測定方法を用いたアポ蛋白eフェノタイプの同定方法 |
| US20010019821A1 (en) * | 1999-03-31 | 2001-09-06 | Smith Jack V. | Method for manufacturing and detecting and normalizing HIV for rapid analysis |
-
2002
- 2002-10-04 JP JP2003534903A patent/JP4153873B2/ja not_active Expired - Fee Related
- 2002-10-04 EP EP02800770A patent/EP1434053B1/de not_active Expired - Lifetime
- 2002-10-04 AT AT02800770T patent/ATE390633T1/de not_active IP Right Cessation
- 2002-10-04 DE DE60225821T patent/DE60225821T2/de not_active Expired - Lifetime
- 2002-10-04 WO PCT/JP2002/010363 patent/WO2003031971A1/ja not_active Ceased
- 2002-10-04 US US10/490,390 patent/US20050266501A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003031971A1 (fr) | 2003-04-17 |
| EP1434053B1 (de) | 2008-03-26 |
| JP4153873B2 (ja) | 2008-09-24 |
| EP1434053A4 (de) | 2005-11-30 |
| US20050266501A1 (en) | 2005-12-01 |
| DE60225821D1 (de) | 2008-05-08 |
| JPWO2003031971A1 (ja) | 2005-01-27 |
| DE60225821T2 (de) | 2009-04-30 |
| EP1434053A1 (de) | 2004-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |