ATE391188T1 - Cst (compartmentalised self tagging) - Google Patents

Cst (compartmentalised self tagging)

Info

Publication number
ATE391188T1
ATE391188T1 AT04798378T AT04798378T ATE391188T1 AT E391188 T1 ATE391188 T1 AT E391188T1 AT 04798378 T AT04798378 T AT 04798378T AT 04798378 T AT04798378 T AT 04798378T AT E391188 T1 ATE391188 T1 AT E391188T1
Authority
AT
Austria
Prior art keywords
cst
tagging
compartmentalized self
compartmentalized
self tagging
Prior art date
Application number
AT04798378T
Other languages
English (en)
Inventor
Philipp Holliger
Zoryana Oliynyk
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE391188T1 publication Critical patent/ATE391188T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Details Of Garments (AREA)
  • Gloves (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Catching Or Destruction (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
AT04798378T 2003-11-03 2004-11-03 Cst (compartmentalised self tagging) ATE391188T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0325653.4A GB0325653D0 (en) 2003-11-03 2003-11-03 CST emulsions

Publications (1)

Publication Number Publication Date
ATE391188T1 true ATE391188T1 (de) 2008-04-15

Family

ID=29725871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04798378T ATE391188T1 (de) 2003-11-03 2004-11-03 Cst (compartmentalised self tagging)

Country Status (9)

Country Link
US (2) US7691576B2 (de)
EP (1) EP1680516B1 (de)
AT (1) ATE391188T1 (de)
DE (1) DE602004012881T2 (de)
DK (1) DK1680516T3 (de)
ES (1) ES2303959T3 (de)
GB (1) GB0325653D0 (de)
WO (1) WO2005045072A1 (de)
ZA (1) ZA200603523B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0325653D0 (en) 2003-11-03 2003-12-10 Medical Res Council CST emulsions
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2530167A1 (de) 2006-05-11 2012-12-05 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2077912B1 (de) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorkohlenstoffemulsionsstabilisierende tenside
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
DK2191016T3 (en) * 2007-08-20 2015-06-08 Gen Hospital Corp INSULATION OF PROTEIN FACTORS BINDING DIRECT OR INDIRECT WITH NUCLEIC ACIDS
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (de) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken
WO2010111231A1 (en) 2009-03-23 2010-09-30 Raindance Technologies, Inc. Manipulation of microfluidic droplets
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
EP4484577A3 (de) 2010-02-12 2025-03-26 Bio-Rad Laboratories, Inc. Digitale analytanalyse
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
EP3412778A1 (de) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Verfahren zur bildung gemischter tröpfchen
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP3216872B1 (de) 2011-06-02 2020-04-01 Bio-Rad Laboratories, Inc. Enzymquantifizierung
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US9701959B2 (en) 2012-02-02 2017-07-11 Invenra Inc. High throughput screen for biologically active polypeptides
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
US9890417B2 (en) * 2014-11-03 2018-02-13 Agilent Technologies, Inc. Signal amplification of fluorescence in situ hybridization
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
JP6934477B2 (ja) 2016-01-19 2021-09-15 ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム 熱安定逆転写酵素
US12116570B2 (en) 2016-09-29 2024-10-15 Roche Sequencing Solutions, Inc. Directed evolution of enzymes by plasmid tagging in droplets
WO2019084538A1 (en) 2017-10-27 2019-05-02 Board Of Regents, The University Of Texas System TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF
US12270026B1 (en) * 2020-03-05 2025-04-08 Ansa Biotechnologies, Inc. Directed evolution method for template-independent polymerases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759226B1 (en) 2000-05-24 2004-07-06 Third Wave Technologies, Inc. Enzymes for the detection of specific nucleic acid sequences
WO1998023733A2 (en) 1996-11-27 1998-06-04 University Of Washington Thermostable polymerases having altered fidelity
ES2230701T3 (es) 1997-07-07 2005-05-01 Medical Research Council Procedimiento de seleccion in vitro.
EP1100889A4 (de) 1998-07-17 2002-03-06 Mirus Corp Micell systeme
GB9900298D0 (en) 1999-01-07 1999-02-24 Medical Res Council Optical sorting method
GB0022458D0 (en) * 2000-09-13 2000-11-01 Medical Res Council Directed evolution method
US7225943B2 (en) * 2000-12-22 2007-06-05 Simplehuman Llc Trash can assembly and improvements thereto
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
EP1801213A3 (de) 2003-11-03 2007-10-24 Medical Research Council Polymerase
GB0325653D0 (en) 2003-11-03 2003-12-10 Medical Res Council CST emulsions

Also Published As

Publication number Publication date
US20070134682A1 (en) 2007-06-14
US20100184071A1 (en) 2010-07-22
DK1680516T3 (da) 2008-07-21
US7691576B2 (en) 2010-04-06
EP1680516A1 (de) 2006-07-19
DE602004012881T2 (de) 2008-10-16
DE602004012881D1 (en) 2008-05-15
ES2303959T3 (es) 2008-09-01
EP1680516B1 (de) 2008-04-02
ZA200603523B (en) 2007-07-25
WO2005045072A1 (en) 2005-05-19
GB0325653D0 (en) 2003-12-10
US8133673B2 (en) 2012-03-13

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