ATE392950T1 - Laserstrahlungsdesorptionsgerät zur manipulation einer flüssigprobe in form von einzeltropfen zur ermöglichung ihrer chemischen und biologischen behandlung - Google Patents

Laserstrahlungsdesorptionsgerät zur manipulation einer flüssigprobe in form von einzeltropfen zur ermöglichung ihrer chemischen und biologischen behandlung

Info

Publication number
ATE392950T1
ATE392950T1 AT05775290T AT05775290T ATE392950T1 AT E392950 T1 ATE392950 T1 AT E392950T1 AT 05775290 T AT05775290 T AT 05775290T AT 05775290 T AT05775290 T AT 05775290T AT E392950 T1 ATE392950 T1 AT E392950T1
Authority
AT
Austria
Prior art keywords
sample
liquid sample
laser radiation
drops
chemical
Prior art date
Application number
AT05775290T
Other languages
English (en)
Inventor
Jean-Christophe Fourrier
Francois Caron
Pierre Tabourier
Christian Druon
Denis Loyaux
Jean-Pierre Lepesant
Christian Rolando
Original Assignee
Univ Lille Sciences Tech
Centre Nat Rech Scient
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Lille Sciences Tech, Centre Nat Rech Scient, Sanofi Aventis filed Critical Univ Lille Sciences Tech
Application granted granted Critical
Publication of ATE392950T1 publication Critical patent/ATE392950T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • H01J49/0418Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/089Virtual walls for guiding liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427Electrowetting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Hydrology & Water Resources (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT05775290T 2004-06-04 2005-06-06 Laserstrahlungsdesorptionsgerät zur manipulation einer flüssigprobe in form von einzeltropfen zur ermöglichung ihrer chemischen und biologischen behandlung ATE392950T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0406081A FR2871076A1 (fr) 2004-06-04 2004-06-04 Dispositif pour desorption par rayonnement laser incorporant une manipulation de l'echantillon liquide sous forme de gouttes individuelles permettant leur traitement chimique et biochimique

Publications (1)

Publication Number Publication Date
ATE392950T1 true ATE392950T1 (de) 2008-05-15

Family

ID=34946330

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05775290T ATE392950T1 (de) 2004-06-04 2005-06-06 Laserstrahlungsdesorptionsgerät zur manipulation einer flüssigprobe in form von einzeltropfen zur ermöglichung ihrer chemischen und biologischen behandlung

Country Status (14)

Country Link
US (1) US7750290B2 (de)
EP (1) EP1750840B1 (de)
JP (1) JP4950035B2 (de)
KR (1) KR101003883B1 (de)
CN (1) CN100515567C (de)
AT (1) ATE392950T1 (de)
AU (1) AU2005259080B2 (de)
BR (1) BRPI0511804A (de)
CA (1) CA2569256C (de)
DE (1) DE602005006271T2 (de)
FR (1) FR2871076A1 (de)
IL (1) IL179829A (de)
MX (1) MXPA06014114A (de)
WO (1) WO2006003292A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109603932A (zh) * 2018-12-12 2019-04-12 深圳大学 一种双聚焦微流体芯片

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2871150B1 (fr) * 2004-06-04 2006-09-22 Univ Lille Sciences Tech Dispositif de manipulation de gouttes destine a l'analyse biochimique, procede de fabrication du dispositif, et systeme d'analyse microfluidique
EP1859330B1 (de) 2005-01-28 2012-07-04 Duke University Vorrichtungen und verfahren zur manipulation von tropfen auf einer leiterplatte
WO2006138543A1 (en) * 2005-06-16 2006-12-28 Core-Microsolutions, Inc. Biosensor detection by means of droplet driving, agitation, and evaporation
US8492168B2 (en) 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8613889B2 (en) 2006-04-13 2013-12-24 Advanced Liquid Logic, Inc. Droplet-based washing
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
WO2007123908A2 (en) 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Droplet-based multiwell operations
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
EP2016189B1 (de) * 2006-04-18 2012-01-25 Advanced Liquid Logic, Inc. Pyrosequenzierung auf tröpfchenbasis
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US7727723B2 (en) 2006-04-18 2010-06-01 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
US9675972B2 (en) 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
US7619217B2 (en) * 2006-05-26 2009-11-17 Purdue Research Foundation High power laser induced acoustic desorption probe
FR2901717A1 (fr) * 2006-05-30 2007-12-07 Centre Nat Rech Scient Procede de traitement de gouttes dans un circuit microfluidique.
JP4651715B2 (ja) * 2006-07-05 2011-03-16 株式会社日立ハイテクノロジーズ 液体分析装置
EP2573562A3 (de) 2007-02-09 2013-10-30 Advanced Liquid Logic, Inc. Tröpfchenaktuatorvorrichtungen und Verfahren zur Manipulation von Kügelchen
WO2009032863A2 (en) 2007-09-04 2009-03-12 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
US9631244B2 (en) 2007-10-17 2017-04-25 Advanced Liquid Logic, Inc. Reagent storage on a droplet actuator
US8460528B2 (en) * 2007-10-17 2013-06-11 Advanced Liquid Logic Inc. Reagent storage and reconstitution for a droplet actuator
CA2709928A1 (en) 2007-12-23 2009-07-09 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods of conducting droplet operations
US8367370B2 (en) * 2008-02-11 2013-02-05 Wheeler Aaron R Droplet-based cell culture and cell assays using digital microfluidics
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
US8187864B2 (en) * 2008-10-01 2012-05-29 The Governing Council Of The University Of Toronto Exchangeable sheets pre-loaded with reagent depots for digital microfluidics
US8053239B2 (en) 2008-10-08 2011-11-08 The Governing Council Of The University Of Toronto Digital microfluidic method for protein extraction by precipitation from heterogeneous mixtures
WO2010040227A1 (en) 2008-10-10 2010-04-15 The Governing Council Of The University Of Toronto Hybrid digital and channel microfluidic devices and methods of use thereof
US9851365B2 (en) 2009-02-26 2017-12-26 The Governing Council Of The University Of Toronto Digital microfluidic liquid-liquid extraction device and method of use thereof
US8202736B2 (en) * 2009-02-26 2012-06-19 The Governing Council Of The University Of Toronto Method of hormone extraction using digital microfluidics
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
CN101670998B (zh) * 2009-09-16 2011-10-26 哈尔滨工业大学 点面电极系统及利用该系统进行微流体驱动的方法
WO2011057197A2 (en) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel electrophoresis and molecular analysis
TWI385029B (zh) * 2009-12-18 2013-02-11 Univ Nat Chiao Tung 產生可移除外殼之包覆式液滴的微流體系統及方法
EP2516669B1 (de) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Enzymassays auf einem tropfenaktuator
US10232374B2 (en) 2010-05-05 2019-03-19 Miroculus Inc. Method of processing dried samples using digital microfluidic device
US9476811B2 (en) 2010-10-01 2016-10-25 The Governing Council Of The University Of Toronto Digital microfluidic devices and methods incorporating a solid phase
DE102010054581A1 (de) * 2010-12-15 2012-06-21 Bruker Daltonik Gmbh Probenpräparation für die Ionisierung mit matrixunterstützter Laserdesorption
WO2012154745A2 (en) 2011-05-09 2012-11-15 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
WO2013016413A2 (en) 2011-07-25 2013-01-31 Advanced Liquid Logic Inc Droplet actuator apparatus and system
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
CN103381376B (zh) * 2012-05-02 2014-12-10 李木 一种无人值守型数字式微流控系统及其控制方法
EP2867645B1 (de) 2012-06-27 2019-06-05 Advanced Liquid Logic, Inc. Verfahren und tropfenaktuatorkonzepte zur reduzierung einer bläschenbildung
CN104136124B (zh) * 2013-01-09 2017-07-25 泰肯贸易股份公司 带有废物空腔的微流体系统
CA2903295A1 (en) 2013-03-05 2014-09-12 Micromass Uk Limited Charging plate for enhancing multiply charged ions by laser desorption
GB201303922D0 (en) * 2013-03-05 2013-04-17 Micromass Ltd Charging plate for enhancing multiply charged ions by laser desorption
JP6622811B2 (ja) 2014-12-31 2019-12-18 アボット・ラボラトリーズAbbott Laboratories デジタルマイクロ流体希釈装置、システムおよび関連方法
BR112017021256A2 (pt) * 2015-04-03 2018-06-26 Abbott Laboratories dispositivos e métodos para a análise de amostras
US10695762B2 (en) 2015-06-05 2020-06-30 Miroculus Inc. Evaporation management in digital microfluidic devices
CN108026494A (zh) 2015-06-05 2018-05-11 米罗库鲁斯公司 限制蒸发和表面结垢的空气基质数字微流控装置和方法
CN109715781A (zh) 2016-08-22 2019-05-03 米罗库鲁斯公司 用于数字微流控设备中的并行液滴控制的反馈系统
CN110383061A (zh) 2016-12-28 2019-10-25 米罗库鲁斯公司 数字微流控设备和方法
US11623219B2 (en) 2017-04-04 2023-04-11 Miroculus Inc. Digital microfluidics apparatuses and methods for manipulating and processing encapsulated droplets
EP3658908B1 (de) 2017-07-24 2025-11-12 Integra Biosciences AG Digitale mikrofluidiksysteme und verfahren mit integrierter plasmasammelvorrichtung
CA3073058A1 (en) 2017-09-01 2019-03-07 Miroculus Inc. Digital microfluidics devices and methods of using them
CN108535239B (zh) * 2018-03-28 2021-05-25 上海艾瑞德生物科技有限公司 基于微液滴的微流控芯片和检测系统
WO2019226919A1 (en) 2018-05-23 2019-11-28 Miroculus Inc. Control of evaporation in digital microfluidics
CN109164073B (zh) * 2018-08-03 2021-12-21 大连大学 用于水体重金属离子测定的数字微流控芯片系统及方法
US10913067B2 (en) * 2018-10-01 2021-02-09 Sharp Life Science (Eu) Limited Barrier droplet configurations against migration between droplets on AM-EWOD devices
JP7022845B2 (ja) * 2018-10-19 2022-02-18 株式会社日立ハイテク 生化学用カートリッジ及び生化学分析装置
EP3917670A4 (de) 2019-01-31 2022-11-02 Miroculus Inc. Nichtverschmutzende zusammensetzungen und verfahren zum manipulieren und verarbeiten von eingekapselten tröpfchen
KR102572486B1 (ko) * 2019-02-25 2023-08-30 고쿠리츠켄큐카이하츠호진 상교기쥬츠 소고켄큐쇼 개방 공간형의 액체 조작 장치
US12582991B2 (en) 2019-02-28 2026-03-24 Integra Biosciences Ag Digital microfluidics devices and methods of using them
CN109894167B (zh) * 2019-03-25 2021-09-28 上海天马微电子有限公司 微流控芯片
CN114206499B (zh) 2019-04-08 2024-10-08 米罗库鲁斯公司 多盒式数字微流控装置和使用方法
US11524298B2 (en) 2019-07-25 2022-12-13 Miroculus Inc. Digital microfluidics devices and methods of use thereof
CN111030418B (zh) * 2019-12-03 2021-04-02 广州大学 一种基于电浸润现象的双腔微泵
US11772093B2 (en) 2022-01-12 2023-10-03 Miroculus Inc. Methods of mechanical microfluidic manipulation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705813A (en) * 1995-11-01 1998-01-06 Hewlett-Packard Company Integrated planar liquid handling system for maldi-TOF MS
US6565727B1 (en) * 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
WO2002007503A1 (en) * 2000-07-25 2002-01-31 The Regents Of The University Of California Electrowetting-driven micropumping
JP2004529463A (ja) * 2001-03-19 2004-09-24 ユィロス・アクチボラグ マイクロ流体システム(ms)
CA2442342A1 (en) * 2001-03-19 2002-09-26 Gyros Ab A microfluidic system (edi)
AU2002359508A1 (en) * 2001-11-26 2003-06-10 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
WO2003071275A1 (de) * 2002-02-22 2003-08-28 Sunyx Surface Nanotechnologies Gmbh Ultraphobe oberfläche mit einer vielzahl reversibel erzeugbarer hydrophiler und/oder oleophiler bereiche
WO2004054455A1 (en) * 2002-12-13 2004-07-01 Pelikan Technologies, Inc. Method and apparatus for measuring analytes
US7329545B2 (en) * 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
US6989234B2 (en) * 2002-09-24 2006-01-24 Duke University Method and apparatus for non-contact electrostatic actuation of droplets
US6911132B2 (en) * 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
JPWO2004051234A1 (ja) * 2002-11-29 2006-04-06 日本電気株式会社 試料乾燥装置およびこれを用いた質量分析装置、質量分析システム
CN1650426A (zh) * 2002-12-17 2005-08-03 富士通株式会社 半导体装置及叠层型半导体装置
WO2005019875A2 (en) * 2003-08-22 2005-03-03 Stratos Biosystems, Llc Electrowetting sample presentation device
FR2871150B1 (fr) * 2004-06-04 2006-09-22 Univ Lille Sciences Tech Dispositif de manipulation de gouttes destine a l'analyse biochimique, procede de fabrication du dispositif, et systeme d'analyse microfluidique

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109603932A (zh) * 2018-12-12 2019-04-12 深圳大学 一种双聚焦微流体芯片
WO2020119282A1 (zh) * 2018-12-12 2020-06-18 深圳大学 一种双聚焦微流体芯片

Also Published As

Publication number Publication date
US20080156983A1 (en) 2008-07-03
EP1750840A1 (de) 2007-02-14
CA2569256A1 (fr) 2006-01-12
CA2569256C (fr) 2012-03-06
BRPI0511804A (pt) 2008-01-15
US7750290B2 (en) 2010-07-06
IL179829A0 (en) 2007-05-15
CN100515567C (zh) 2009-07-22
WO2006003292A1 (fr) 2006-01-12
FR2871076A1 (fr) 2005-12-09
MXPA06014114A (es) 2007-03-07
JP4950035B2 (ja) 2012-06-13
DE602005006271T2 (de) 2009-07-16
JP2008501944A (ja) 2008-01-24
HK1109101A1 (zh) 2008-05-30
AU2005259080A1 (en) 2006-01-12
EP1750840B1 (de) 2008-04-23
KR20070052245A (ko) 2007-05-21
CN101035621A (zh) 2007-09-12
KR101003883B1 (ko) 2010-12-30
IL179829A (en) 2010-12-30
DE602005006271D1 (de) 2008-06-05
AU2005259080B2 (en) 2010-05-20

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