ATE394107T1 - Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure - Google Patents

Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure

Info

Publication number: ATE394107T1
Authority: AT; Austria
Prior art keywords: colon; prevention; treatment; acid; microadenoma
Prior art date: 1996-05-23

Application number

AT97925934T

Other languages

English (en)

Inventor

Joyce Gibson

Leonhard Capuano

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-23

Filing date

1997-05-22

Publication date

2008-05-15

1997-05-22 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2008-05-15 Application granted granted Critical

2008-05-15 Publication of ATE394107T1 publication Critical patent/ATE394107T1/de

Links

230000002265 prevention Effects 0.000 title abstract 3
239000002253 acid Substances 0.000 title abstract 2
206010048832 Colon adenoma Diseases 0.000 title 1
210000001072 colon Anatomy 0.000 title 1
238000000034 method Methods 0.000 abstract 3
208000003200 Adenoma Diseases 0.000 abstract 1
206010001233 Adenoma benign Diseases 0.000 abstract 1
206010009944 Colon cancer Diseases 0.000 abstract 1
208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000003613 bile acid Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
231100000357 carcinogen Toxicity 0.000 abstract 1
239000003183 carcinogenic agent Substances 0.000 abstract 1
231100000433 cytotoxic Toxicity 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 abstract 1
229960003964 deoxycholic acid Drugs 0.000 abstract 1
KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT97925934T 1996-05-23 1997-05-22 Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure ATE394107T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1820296P	1996-05-23	1996-05-23

Publications (1)

Publication Number	Publication Date
ATE394107T1 true ATE394107T1 (de)	2008-05-15

Family

ID=21786767

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97925934T ATE394107T1 (de)	1996-05-23	1997-05-22	Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure

Country Status (10)

Country	Link
US (1)	US6426340B1 (de)
EP (1)	EP0906106B1 (de)
JP (2)	JP2000510858A (de)
AT (1)	ATE394107T1 (de)
AU (1)	AU3091597A (de)
CA (1)	CA2253593C (de)
DE (1)	DE69738667D1 (de)
ES (1)	ES2306459T3 (de)
PT (1)	PT906106E (de)
WO (1)	WO1997044043A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2224523C2 (ru) *	1998-07-24	2004-02-27	Сео Хонг Ю	Водный раствор, содержащий желчную кислоту, и способ его получения
ES2211184T3 (es) *	1998-08-06	2004-07-01	Wolfgang Stremmel	Fosfatidilcolina como medicamento con efecto protector de mucosas.
AP1954A (en) *	1999-09-28	2009-02-10	Panacea Biotec Ltd	Controlled release compositions comprising nimesulide.
US7053076B2 (en)	2001-08-29	2006-05-30	Xenoport, Inc.	Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
CA2503811A1 (en) *	2002-11-01	2004-05-21	James Kaput	Identification of diet-regulated disease-associated genes
US20090074785A1 (en) *	2007-01-16	2009-03-19	Smith Jeffrey W	Compositions and methods for treatment of colorectal cancer
EP2255813A1 (de) *	2009-05-29	2010-12-01	The Royal College of Surgeons in Ireland	Ursodeoxycholsäurederivate zur Behandlung von Diarrhöe
ES2586931T3 (es)	2010-11-04	2016-10-19	Albireo Ab	Inhibidores de IBAT para el tratamiento de enfermedades hepáticas
CN106659726A (zh)	2014-06-25	2017-05-10	Ea制药株式会社	固体制剂及其着色防止或着色减少方法
EP3413875B1 (de)	2016-02-09	2020-01-29	Albireo AB	Cholestyraminpellets und verfahren zur herstellung davon
EP3413877B1 (de)	2016-02-09	2021-04-07	Albireo AB	Orale cholestyraminformulierungen und verwendung davon
EP3413878B1 (de)	2016-02-09	2021-04-14	Albireo AB	Orale cholestyraminformulierungen und verwendung davon
JP2020530448A (ja)	2017-08-09	2020-10-22	アルビレオ・アクチボラグ	コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用
JP7391048B2 (ja)	2018-06-05	2023-12-04	アルビレオ・アクチボラグ	ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
MX2020013839A (es)	2018-06-20	2021-03-25	Albireo Ab	Formulacion farmaceutica de odevixibat.
US11801226B2 (en)	2018-06-20	2023-10-31	Albireo Ab	Pharmaceutical formulation of odevixibat
GB201812382D0 (en)	2018-07-30	2018-09-12	Nzp Uk Ltd	Compounds
US11549878B2 (en)	2018-08-09	2023-01-10	Albireo Ab	In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en)	2018-08-09	2021-05-18	Albireo Ab	Oral cholestyramine formulation and use thereof
US10722457B2 (en)	2018-08-09	2020-07-28	Albireo Ab	Oral cholestyramine formulation and use thereof
RS63899B1 (sr)	2019-02-06	2023-02-28	Albireo Ab	Benzotiadiazepinska jedinjenja i njihova upotreba kao modulatora žučnih kiselina
TWI835997B (zh)	2019-02-06	2024-03-21	瑞典商艾爾比瑞歐公司	苯并噻氮呯化合物及其用作膽酸調節劑之用途
EP4069359B1 (de)	2019-12-04	2024-01-03	Albireo AB	Benzothia(di)azepinverbindungen und ihre verwendung als gallensäuremodulatoren
JP7665620B2 (ja)	2019-12-04	2025-04-21	アルビレオ・アクチボラグ	ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
CA3158181A1 (en)	2019-12-04	2021-06-10	Albireo Ab	Benzothia(di)azepine compounds and their use as bile acid modulators
US11014898B1 (en)	2020-12-04	2021-05-25	Albireo Ab	Benzothiazepine compounds and their use as bile acid modulators
BR112022010505A2 (pt)	2019-12-04	2022-09-06	Albireo Ab	Compostos de benzotia(di)azepina e seu uso como moduladores do ácido biliar
CA3186857A1 (en)	2020-08-03	2022-02-10	Per-Goran Gillberg	Benzothia(di)azepine compounds and their use as bile acid modulators
AU2021379076A1 (en)	2020-11-12	2023-06-08	Albireo Ab	Odevixibat for treating progressive familial intrahepatic cholestasis (pfic)
AU2021390172A1 (en)	2020-12-04	2023-06-22	Albireo Ab	Benzothia(di)azepine compounds and their use as bile acid modulators
TW202313579A (zh)	2021-06-03	2023-04-01	瑞典商艾爾比瑞歐公司	苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8825526D0 (en) *	1988-11-01	1988-12-07	Enzymatix Ltd	Diagnosis
US5175320A (en) *	1989-04-17	1992-12-29	Giuliani S.P.A.	Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5843929A (en)	1996-03-22	1998-12-01	Mayo Foundation For Medical Education And Research	Chemoprevention of metachronous adenomatous colorectal polyps

1997
- 1997-05-22 AT AT97925934T patent/ATE394107T1/de not_active IP Right Cessation
- 1997-05-22 ES ES97925934T patent/ES2306459T3/es not_active Expired - Lifetime
- 1997-05-22 CA CA002253593A patent/CA2253593C/en not_active Expired - Fee Related
- 1997-05-22 PT PT97925934T patent/PT906106E/pt unknown
- 1997-05-22 AU AU30915/97A patent/AU3091597A/en not_active Abandoned
- 1997-05-22 JP JP09541562A patent/JP2000510858A/ja active Pending
- 1997-05-22 DE DE69738667T patent/DE69738667D1/de not_active Expired - Lifetime
- 1997-05-22 EP EP97925934A patent/EP0906106B1/de not_active Expired - Lifetime
- 1997-05-22 WO PCT/EP1997/002632 patent/WO1997044043A1/en not_active Ceased
2000
- 2000-10-06 US US09/684,585 patent/US6426340B1/en not_active Expired - Fee Related
2009
- 2009-11-02 JP JP2009252071A patent/JP2010059175A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
EP0906106B1 (de)	2008-05-07
JP2000510858A (ja)	2000-08-22
JP2010059175A (ja)	2010-03-18
EP0906106A1 (de)	1999-04-07
ES2306459T3 (es)	2008-11-01
AU3091597A (en)	1997-12-09
WO1997044043A1 (en)	1997-11-27
PT906106E (pt)	2008-08-07
CA2253593C (en)	2008-07-08
DE69738667D1 (de)	2008-06-19
US6426340B1 (en)	2002-07-30
CA2253593A1 (en)	1997-11-27

Legal Events

Date

Code

Title

Description

2008-11-15

UEP

Publication of translation of european patent specification

Ref document number: 0906106

Country of ref document: EP

2012-02-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69738667D1 (de)	2008-06-19	Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure
NO970039D0 (no)	1997-01-06	Fremgangsmåte for inhibering av cancer matastaser ved oral administrering av opplöselig modifisert sitruspektin
IS4972A (is)	1999-02-10	Notkun klóbindiefnisins klíókínól við að framleiða lyfjablöndu til að meðhöndla Alzheimers-sjúkdóm
EP0902789A4 (de)	1999-04-14
TR200101335T2 (tr)	2001-09-21	İktidarsızlık tedavisi için pirazolopirimidinon türevleri
TR199900827T2 (xx)	1999-07-21	Siklooksigenaz-2 inhibit�rlerinin neoplazinin tedavisinde ve �nlenmesinde kullan�m�.
ATE170077T1 (de)	1998-09-15	Verfahren zur behandlung von krebs durch kombinationstherapie mit 2'- halomethylidenderivaten und einem s- oder m-phase spezifischen antineoplastischen wirkstoff
NZ308789A (en)	1999-07-29	Tetralin derivatives and medicaments
SG144712A1 (en)	2008-08-28	Nordihydroguaiartic derivaties for use in treatment of tumors
MY119375A (en)	2005-05-31	Treatment of tinnitus using neuroprotective agents
DE60022525T2 (de)	2006-06-14	Ramipril zur vorbeugung von kardiovaskulären vorfällen
IL113566A0 (en)	1995-08-31	Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration
MY118526A (en)	2004-11-30	Method for improving the pharmacokinetics of tipranavir
MY121623A (en)	2006-02-28	Methods of preventing breast cancer.
MY118986A (en)	2005-02-28	Use of (alpha)-1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
DK1124566T3 (da)	2003-06-02	Ikke-fermenteret osmotisk laxativ til behandling og forebyggelse af colorectale cancere
TR199701520T1 (xx)	1998-04-21	Ac�n�n iyile�tirilmesi i�in analjesik bile�ikleri �reten h�cre soyu.
NO983177L (no)	1998-07-10	Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
HU9700661D0 (en)	1997-05-28	Use of alpha-1-adrenoreceptor antagonists for profilacting and treating cancer
DE69329760D1 (de)	2001-01-18	Behandlung von magen- und darmgeschwüren mit morphogenen
AU6846300A (en)	2001-03-13	Use of cyamemazine for cold turkey benzodiazepine treatment
AU4042795A (en)	1996-02-22	Treatment of non-small cell lung carcinoma
MX9604692A (es)	1998-04-30	Derivados de quinoxalina para el tratamiento de tinnitus.
IL126158A0 (en)	1999-05-09	Method for treating substance abuse
WO1995005364A3 (en)	1995-03-23	Inhibitors of biogenic amine transporters