ATE396273T1 - G-protein chimären - Google Patents

G-protein chimären

Info

Publication number: ATE396273T1
Authority: AT; Austria
Prior art keywords: amino acids; chimeric; compound; observing; alpha
Prior art date: 1997-09-13

Application number

AT04078332T

Other languages

English (en)

Inventor

Andrew J Brown

Simon J Dowell

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-13

Filing date

1998-09-11

Publication date

2008-06-15

1998-09-11 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2008-06-15 Application granted granted Critical

2008-06-15 Publication of ATE396273T1 publication Critical patent/ATE396273T1/de

Links

150000001413 amino acids Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
230000006303 immediate early viral mRNA transcription Effects 0.000 abstract 2
210000005253 yeast cell Anatomy 0.000 abstract 2
108700008625 Reporter Genes Proteins 0.000 abstract 1
240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
210000004899 c-terminal region Anatomy 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4722—G-proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT04078332T 1997-09-13 1998-09-11 G-protein chimären ATE396273T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9719496.3A GB9719496D0 (en)	1997-09-13	1997-09-13	G protien chimeras

Publications (1)

Publication Number	Publication Date
ATE396273T1 true ATE396273T1 (de)	2008-06-15

Family

ID=10819017

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT04078332T ATE396273T1 (de)	1997-09-13	1998-09-11	G-protein chimären
AT98942898T ATE291627T1 (de)	1997-09-13	1998-09-11	Chimäre des g-proteins

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT98942898T ATE291627T1 (de)	1997-09-13	1998-09-11	Chimäre des g-proteins

Country Status (9)

Country	Link
US (1)	US6509447B1 (de)
EP (2)	EP1533379B1 (de)
JP (2)	JP4587563B2 (de)
AT (2)	ATE396273T1 (de)
AU (1)	AU9086398A (de)
DE (2)	DE69829485T2 (de)
ES (1)	ES2308104T3 (de)
GB (1)	GB9719496D0 (de)
WO (1)	WO1999014344A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7067277B1 (en)	1999-12-23	2006-06-27	H. Lundbeck A/S	Chimeric G proteins and uses thereof
US20070105096A1 (en) *	2002-04-16	2007-05-10	Katsutoshi Sasaki	Endocrine cell lines and methods of using same
DE10233516A1 (de) *	2002-07-23	2004-02-12	Aventis Pharma Deutschland Gmbh	Verfahren zur Identifizierung von Substanzen
CA2605228A1 (en)	2005-04-27	2007-03-08	Arena Pharmaceuticals, Inc.	Combination therapy for the treatment of obesity and diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level
MX2007016508A (es)	2005-06-30	2008-03-04	Prosidion Ltd	Agonistas del receptor acoplado a la proteina g.
US7833730B2 (en)	2006-04-11	2010-11-16	Arena Pharmaceuticals, Inc.	Methods of using GPR119 to identify compounds useful for increasing bone mass in an individual
US20100048632A1 (en)	2007-01-04	2010-02-25	Matthew Colin Thor Fyfe	Piperidine GPCR Agonists
PE20081849A1 (es)	2007-01-04	2009-01-26	Prosidion Ltd	Derivados de piperidin-4-il-propoxi-benzamida como agonistas de gpcr
PE20081659A1 (es)	2007-01-04	2008-10-24	Prosidion Ltd	Agonistas de gpcr
WO2009034388A1 (en)	2007-09-10	2009-03-19	Prosidion Limited	Compounds for the treatment of metabolic disorders
GB0720390D0 (en)	2007-10-18	2007-11-28	Prosidion Ltd	G-Protein coupled receptor agonists
GB0720389D0 (en)	2007-10-18	2008-11-12	Prosidion Ltd	G-Protein Coupled Receptor Agonists
EP2108960A1 (de)	2008-04-07	2009-10-14	Arena Pharmaceuticals, Inc.	Verfahren zur Verwendung eines A G Protein-gekoppelten Rezeptors zur Identifikation von Peptid YY (PYY) Sekretagoga und nützliche Verbindungen zur Behandlung von durch (PYY) Sekretagoga modulierten Zuständen und nützliche Verbindungen zur Behandlung von Zuständen durch PYY
GB0904284D0 (en)	2009-03-12	2009-04-22	Prosidion Ltd	Compounds for the treatment of metabolic disorders
GB0904285D0 (en)	2009-03-12	2009-04-22	Prosidion Ltd	Compounds for the treatment of metabolic disorders
GB0904287D0 (en)	2009-03-12	2009-04-22	Prosidion Ltd	Compounds for the treatment of metabolic disorders
US9809862B2 (en) *	2014-08-11	2017-11-07	Georgia Tech Research Corporation	G-protein coupled receptor (GPCR)-based biosensors and uses thereof
CA3152190A1 (en) *	2019-08-26	2021-03-04	The Brigham & Women's Hospital, Inc.	Compositions and uses for engineered therapeutic microbes and associated receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5691188A (en) *	1994-02-14	1997-11-25	American Cyanamid Company	Transformed yeast cells expressing heterologous G-protein coupled receptor
WO1998016557A1 (en) *	1996-10-11	1998-04-23	The General Hospital Corporation	Assays for g-protein-linked receptors

1997
- 1997-09-13 GB GBGB9719496.3A patent/GB9719496D0/en not_active Ceased
1998
- 1998-09-11 JP JP2000511882A patent/JP4587563B2/ja not_active Expired - Fee Related
- 1998-09-11 EP EP04078332A patent/EP1533379B1/de not_active Expired - Lifetime
- 1998-09-11 AU AU90863/98A patent/AU9086398A/en not_active Abandoned
- 1998-09-11 AT AT04078332T patent/ATE396273T1/de not_active IP Right Cessation
- 1998-09-11 WO PCT/GB1998/002759 patent/WO1999014344A1/en not_active Ceased
- 1998-09-11 DE DE69829485T patent/DE69829485T2/de not_active Expired - Lifetime
- 1998-09-11 ES ES04078332T patent/ES2308104T3/es not_active Expired - Lifetime
- 1998-09-11 US US09/508,429 patent/US6509447B1/en not_active Expired - Fee Related
- 1998-09-11 AT AT98942898T patent/ATE291627T1/de not_active IP Right Cessation
- 1998-09-11 EP EP98942898A patent/EP1012311B1/de not_active Expired - Lifetime
- 1998-09-11 DE DE69839536T patent/DE69839536D1/de not_active Expired - Lifetime
2010
- 2010-07-14 JP JP2010159611A patent/JP5108062B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1533379A1 (de)	2005-05-25
EP1012311A1 (de)	2000-06-28
ES2308104T3 (es)	2008-12-01
DE69829485T2 (de)	2006-05-04
JP5108062B2 (ja)	2012-12-26
JP4587563B2 (ja)	2010-11-24
AU9086398A (en)	1999-04-05
DE69839536D1 (de)	2008-07-03
WO1999014344A1 (en)	1999-03-25
EP1012311B1 (de)	2005-03-23
EP1533379B1 (de)	2008-05-21
DE69829485D1 (de)	2005-04-28
JP2010279369A (ja)	2010-12-16
ATE291627T1 (de)	2005-04-15
GB9719496D0 (en)	1997-11-19
US6509447B1 (en)	2003-01-21
JP2001516587A (ja)	2001-10-02

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Legal Events

Date	Code	Title	Description
2008-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties