ATE396277T1 - Verfahren zum nachweis einer milden beeinträchtigten glukosetoleranz oder insulin- hyposekretion - Google Patents
Verfahren zum nachweis einer milden beeinträchtigten glukosetoleranz oder insulin- hyposekretionInfo
- Publication number
- ATE396277T1 ATE396277T1 AT03715457T AT03715457T ATE396277T1 AT E396277 T1 ATE396277 T1 AT E396277T1 AT 03715457 T AT03715457 T AT 03715457T AT 03715457 T AT03715457 T AT 03715457T AT E396277 T1 ATE396277 T1 AT E396277T1
- Authority
- AT
- Austria
- Prior art keywords
- myoinositol
- glucose tolerance
- impaired glucose
- quantifying
- sample
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
- 208000002705 Glucose Intolerance Diseases 0.000 title abstract 3
- 201000009104 prediabetes syndrome Diseases 0.000 title abstract 3
- 102000004877 Insulin Human genes 0.000 title abstract 2
- 108090001061 Insulin Proteins 0.000 title abstract 2
- 229940125396 insulin Drugs 0.000 title abstract 2
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 5
- 229960000367 inositol Drugs 0.000 abstract 5
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 5
- 108091000080 Phosphotransferase Proteins 0.000 abstract 3
- 102000020233 phosphotransferase Human genes 0.000 abstract 3
- CXONXVMMINSQBV-NNYOXOHSSA-N (2r,3r,4s,5r)-5-[[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate Chemical compound NC(=S)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)[O-])=C1 CXONXVMMINSQBV-NNYOXOHSSA-N 0.000 abstract 2
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 2
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Insulating Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002097121 | 2002-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396277T1 true ATE396277T1 (de) | 2008-06-15 |
Family
ID=28671856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03715457T ATE396277T1 (de) | 2002-03-29 | 2003-03-27 | Verfahren zum nachweis einer milden beeinträchtigten glukosetoleranz oder insulin- hyposekretion |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7452687B2 (de) |
| EP (2) | EP1491636B1 (de) |
| JP (2) | JP4466912B2 (de) |
| CN (2) | CN101565740A (de) |
| AT (1) | ATE396277T1 (de) |
| AU (1) | AU2003227237A1 (de) |
| DE (2) | DE60321151D1 (de) |
| ES (2) | ES2333181T3 (de) |
| WO (1) | WO2003083133A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006129513A1 (ja) | 2005-05-30 | 2006-12-07 | Ajinomoto Co., Inc. | 肝疾患評価装置、肝疾患評価方法、肝疾患評価システム、肝疾患評価プログラムおよび記録媒体 |
| JP4581994B2 (ja) | 2002-12-09 | 2010-11-17 | 味の素株式会社 | 生体状態情報処理装置、生体状態情報処理方法、生体状態情報管理システム、プログラム、および、記録媒体 |
| US7148041B2 (en) * | 2003-09-25 | 2006-12-12 | Allergan, Inc. | Animal product free media and processes for obtaining a botulinum toxin |
| EP2172775A4 (de) | 2007-06-25 | 2010-12-01 | Ajinomoto Kk | Verfahren zur bewertung der anreicherung von viszeralfett |
| WO2009054350A1 (ja) * | 2007-10-25 | 2009-04-30 | Ajinomoto Co., Inc. | 耐糖能異常の評価方法 |
| JP5722548B2 (ja) * | 2010-03-31 | 2015-05-20 | シーシーアイ株式会社 | バイオセンサ |
| GB201017547D0 (en) * | 2010-10-18 | 2010-12-01 | Univ Cardiff | Method and device for the detection of sulphur containing species |
| JP5815362B2 (ja) | 2011-10-17 | 2015-11-17 | シスメックス株式会社 | 耐糖能分析装置、耐糖能分析システム及びコンピュータプログラム |
| RU2498306C2 (ru) * | 2011-12-23 | 2013-11-10 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский центр профилактической медицины" Министерства здравоохранения Российской Федерации (ФГБУ "ГНИЦПМ" Минздрава России) | Способ раннего выявления высокого риска развития нарушения толерантности к глюкозе на фоне приема метопролола у больных стабильной стенокардией напряжения |
| CN102645414B (zh) * | 2012-04-06 | 2014-04-02 | 上海蓝怡科技有限公司 | 测定尿液肌醇的试剂盒 |
| JP2015099094A (ja) * | 2013-11-19 | 2015-05-28 | 国立大学法人徳島大学 | ３次元イムノクロマトグラフィ方式を用いた糖尿病検査診断用シート、糖尿病検査診断用デバイス、およびミオイノシトールの検出方法 |
| CN103937870B (zh) * | 2014-04-25 | 2016-05-25 | 中国人民解放军第四军医大学 | 一种连续检测胰岛素敏感性的方法 |
| CN107003315B (zh) * | 2014-12-25 | 2018-09-25 | 株式会社日立制作所 | 胰岛素分泌能力分析装置、具备该装置的胰岛素分泌能力分析系统以及胰岛素分泌能力分析方法 |
| CN115901909B (zh) * | 2021-08-12 | 2026-04-21 | 西南医科大学附属医院 | 一种定量检测血液中肌肉肌醇的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750348A (en) * | 1989-03-08 | 1998-05-12 | The University Of Virginia Patents Foundation | Method for detecting insulin resistance |
| ATE177153T1 (de) | 1990-09-18 | 1999-03-15 | Asahi Chemical Ind | Myo-inositoldehydrogenase |
| JPH0661278B2 (ja) | 1990-09-18 | 1994-08-17 | 旭化成工業株式会社 | ミオイノシトールの高感度定量法および定量用組成物 |
| JP3251976B2 (ja) | 1992-06-23 | 2002-01-28 | 旭化成株式会社 | ミオ・イノシトールデヒドロゲナーゼを生産する実質上純粋な微生物 |
| WO1998042863A1 (en) * | 1997-03-26 | 1998-10-01 | Asahi Kasei Kogyo Kabushiki Kaisha | Highly sensitive method for assaying chiro-inositol and compositions for the assay |
| WO1999060406A1 (en) | 1998-05-21 | 1999-11-25 | Insmed Pharmaceuticals, Inc. | Myo-inositol as a predictor of glycemic control in mammals |
| US6309852B1 (en) | 1998-12-11 | 2001-10-30 | Kyowa Medex Co., Ltd. | Method and reagent for quantitative determination of 1,5-anhydroglucitol |
| JP4412780B2 (ja) * | 1998-12-11 | 2010-02-10 | 協和メデックス株式会社 | １，５−アンヒドログルシトールの定量法および定量試薬 |
| JP2000298131A (ja) | 1999-04-14 | 2000-10-24 | Ryuzo Kawamori | 前糖尿病状態の検出方法 |
| JP3975279B2 (ja) | 1999-11-01 | 2007-09-12 | 旭化成ファーマ株式会社 | 糖尿病予備群の検査方法 |
| DE602004022884D1 (de) | 2003-07-11 | 2009-10-08 | Panasonic Corp | Aufzeichnungsmedium, Aufzeichnungsverfahren, Wiedergabevorrichtung und -verfahren sowie computerlesbares Programm |
| WO2009012446A2 (en) * | 2007-07-18 | 2009-01-22 | Marvell World Trade Ltd. | Access point with simultaneous downlink transmission of independent data for multiple client stations |
-
2003
- 2003-03-27 WO PCT/JP2003/003771 patent/WO2003083133A1/ja not_active Ceased
- 2003-03-27 AT AT03715457T patent/ATE396277T1/de not_active IP Right Cessation
- 2003-03-27 AU AU2003227237A patent/AU2003227237A1/en not_active Abandoned
- 2003-03-27 JP JP2003580566A patent/JP4466912B2/ja not_active Expired - Lifetime
- 2003-03-27 CN CNA2009100048902A patent/CN101565740A/zh active Pending
- 2003-03-27 ES ES08003297T patent/ES2333181T3/es not_active Expired - Lifetime
- 2003-03-27 ES ES03715457T patent/ES2302919T3/es not_active Expired - Lifetime
- 2003-03-27 US US10/509,120 patent/US7452687B2/en not_active Expired - Lifetime
- 2003-03-27 EP EP03715457A patent/EP1491636B1/de not_active Expired - Lifetime
- 2003-03-27 DE DE60321151T patent/DE60321151D1/de not_active Expired - Lifetime
- 2003-03-27 CN CNB038097346A patent/CN100526473C/zh not_active Expired - Fee Related
- 2003-03-27 DE DE60330411T patent/DE60330411D1/de not_active Expired - Lifetime
- 2003-03-27 EP EP08003297A patent/EP1923469B1/de not_active Expired - Lifetime
-
2008
- 2008-10-09 US US12/248,876 patent/US20090042279A1/en not_active Abandoned
-
2010
- 2010-01-22 JP JP2010011525A patent/JP5004367B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1491636A1 (de) | 2004-12-29 |
| EP1491636A4 (de) | 2006-07-26 |
| ES2302919T3 (es) | 2008-08-01 |
| JP5004367B2 (ja) | 2012-08-22 |
| AU2003227237A1 (en) | 2003-10-13 |
| EP1491636B1 (de) | 2008-05-21 |
| EP1923469A1 (de) | 2008-05-21 |
| CN100526473C (zh) | 2009-08-12 |
| JP4466912B2 (ja) | 2010-05-26 |
| HK1070923A1 (en) | 2005-06-30 |
| CN1650025A (zh) | 2005-08-03 |
| EP1923469B1 (de) | 2009-12-02 |
| DE60330411D1 (de) | 2010-01-14 |
| DE60321151D1 (de) | 2008-07-03 |
| JPWO2003083133A1 (ja) | 2005-08-04 |
| US20090042279A1 (en) | 2009-02-12 |
| CN101565740A (zh) | 2009-10-28 |
| ES2333181T3 (es) | 2010-02-17 |
| HK1114532A1 (en) | 2008-10-31 |
| JP2010094135A (ja) | 2010-04-30 |
| US20050214885A1 (en) | 2005-09-29 |
| US7452687B2 (en) | 2008-11-18 |
| WO2003083133A1 (en) | 2003-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |