ATE397663T1 - Humane ltrpc7 proteine, dafür kodierende nukleinsäuren und deren verwendungen - Google Patents
Humane ltrpc7 proteine, dafür kodierende nukleinsäuren und deren verwendungenInfo
- Publication number
- ATE397663T1 ATE397663T1 AT01270129T AT01270129T ATE397663T1 AT E397663 T1 ATE397663 T1 AT E397663T1 AT 01270129 T AT01270129 T AT 01270129T AT 01270129 T AT01270129 T AT 01270129T AT E397663 T1 ATE397663 T1 AT E397663T1
- Authority
- AT
- Austria
- Prior art keywords
- ltrpc7
- methods
- calcium
- proteins
- human
- Prior art date
Links
- 101000844518 Homo sapiens Transient receptor potential cation channel subfamily M member 7 Proteins 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000003611 TRPM7 Human genes 0.000 abstract 4
- 101150045183 TRPM7 gene Proteins 0.000 abstract 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 3
- 229910052791 calcium Inorganic materials 0.000 abstract 3
- 239000011575 calcium Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108091006146 Channels Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 102000003615 TRPM2 Human genes 0.000 abstract 1
- 101150095096 TRPM2 gene Proteins 0.000 abstract 1
- 108010037150 Transient Receptor Potential Channels Proteins 0.000 abstract 1
- 102000011753 Transient Receptor Potential Channels Human genes 0.000 abstract 1
- 230000001086 cytosolic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 230000037041 intracellular level Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24823500P | 2000-11-13 | 2000-11-13 | |
| US25446800P | 2000-12-08 | 2000-12-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397663T1 true ATE397663T1 (de) | 2008-06-15 |
Family
ID=26939221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01270129T ATE397663T1 (de) | 2000-11-13 | 2001-11-13 | Humane ltrpc7 proteine, dafür kodierende nukleinsäuren und deren verwendungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8580525B2 (de) |
| EP (1) | EP1337635B1 (de) |
| JP (1) | JP4393065B2 (de) |
| AT (1) | ATE397663T1 (de) |
| AU (1) | AU2002253807B2 (de) |
| CA (1) | CA2428698C (de) |
| DE (1) | DE60134336D1 (de) |
| WO (1) | WO2002059307A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002059307A2 (en) * | 2000-11-13 | 2002-08-01 | The Queen's Medical Center | Human ltrpc7 proteins, nucleic acid molecules encoding them, and uses thereof |
| CA2517981A1 (en) * | 2003-03-05 | 2004-09-16 | Metabolex, Inc. | Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-trp |
| US20070083941A1 (en) * | 2005-10-06 | 2007-04-12 | Wyeth | Rat TRPM7 polynucleotide and encoded protein |
| EP3548888B1 (de) | 2016-12-02 | 2023-04-05 | Sophion Bioscience A/S | Dichtungsverstärker |
| WO2018100206A1 (en) * | 2016-12-02 | 2018-06-07 | Sophion Bioscience A/S | Seal enhancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1048727B1 (de) | 1998-11-12 | 2006-05-17 | Eiken Kagaku Kabushiki Kaisha | Gen, welches für neues transmembranprotein kodiert |
| EP2006300A3 (de) * | 1998-12-30 | 2009-03-11 | Beth Israel Deaconess Medical Center, Inc. | Charakterisierung einer Calciumkanalfamilie |
| CA2370519C (en) | 1999-04-26 | 2010-07-20 | Beth Israel Deaconess Medical Center, Inc. | Nucleic acids encoding a mutt domain-containing polypeptide |
| EP1307555A2 (de) * | 2000-07-31 | 2003-05-07 | Millennium Pharmaceuticals, Inc. | 18610, humaner transienter rezeptor und seine verwendungen |
| US20040010118A1 (en) * | 2000-08-16 | 2004-01-15 | Zerhusen Bryan D. | Novel proteins and nucleic acids encoding same |
| WO2002059307A2 (en) * | 2000-11-13 | 2002-08-01 | The Queen's Medical Center | Human ltrpc7 proteins, nucleic acid molecules encoding them, and uses thereof |
-
2001
- 2001-11-13 WO PCT/US2001/047784 patent/WO2002059307A2/en not_active Ceased
- 2001-11-13 CA CA2428698A patent/CA2428698C/en not_active Expired - Fee Related
- 2001-11-13 JP JP2002559792A patent/JP4393065B2/ja not_active Expired - Fee Related
- 2001-11-13 EP EP01270129A patent/EP1337635B1/de not_active Expired - Lifetime
- 2001-11-13 DE DE60134336T patent/DE60134336D1/de not_active Expired - Lifetime
- 2001-11-13 AU AU2002253807A patent/AU2002253807B2/en not_active Ceased
- 2001-11-13 AT AT01270129T patent/ATE397663T1/de not_active IP Right Cessation
-
2008
- 2008-05-28 US US12/128,471 patent/US8580525B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60134336D1 (de) | 2008-07-17 |
| US20090098546A1 (en) | 2009-04-16 |
| CA2428698C (en) | 2012-08-21 |
| AU2002253807B2 (en) | 2007-10-18 |
| CA2428698A1 (en) | 2002-08-01 |
| WO2002059307A2 (en) | 2002-08-01 |
| JP4393065B2 (ja) | 2010-01-06 |
| JP2004535549A (ja) | 2004-11-25 |
| US8580525B2 (en) | 2013-11-12 |
| EP1337635A2 (de) | 2003-08-27 |
| EP1337635B1 (de) | 2008-06-04 |
| WO2002059307A3 (en) | 2003-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |