ATE397672T1 - Katalytische rnas mit aminoacylierender aktivität - Google Patents

Katalytische rnas mit aminoacylierender aktivität

Info

Publication number
ATE397672T1
ATE397672T1 AT00982217T AT00982217T ATE397672T1 AT E397672 T1 ATE397672 T1 AT E397672T1 AT 00982217 T AT00982217 T AT 00982217T AT 00982217 T AT00982217 T AT 00982217T AT E397672 T1 ATE397672 T1 AT E397672T1
Authority
AT
Austria
Prior art keywords
molecules
catalytic
activity
catalytic rnas
aminoacylation
Prior art date
Application number
AT00982217T
Other languages
English (en)
Inventor
Suga Hiroaki
Kourouklis Dimitrios
Hirohide Saito
Nick Lee
Neil Bonzagni
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE397672T1 publication Critical patent/ATE397672T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
AT00982217T 1999-11-24 2000-11-22 Katalytische rnas mit aminoacylierender aktivität ATE397672T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16733199P 1999-11-24 1999-11-24
US21438200P 2000-06-28 2000-06-28

Publications (1)

Publication Number Publication Date
ATE397672T1 true ATE397672T1 (de) 2008-06-15

Family

ID=26863053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00982217T ATE397672T1 (de) 1999-11-24 2000-11-22 Katalytische rnas mit aminoacylierender aktivität

Country Status (8)

Country Link
US (1) US7001723B1 (de)
EP (1) EP1232285B1 (de)
JP (1) JP4745577B2 (de)
AT (1) ATE397672T1 (de)
AU (1) AU1927601A (de)
CA (1) CA2391433C (de)
DE (1) DE60039120D1 (de)
WO (1) WO2001038582A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE437946T1 (de) 2002-02-15 2009-08-15 Univ New York State Res Found Ribozyme mit breiter trna-aminoacylierungswirkung
WO2007066627A1 (ja) * 2005-12-06 2007-06-14 The University Of Tokyo 多目的アシル化触媒とその用途
JP5200241B2 (ja) 2006-11-17 2013-06-05 国立大学法人 東京大学 Ｎ末端に非天然骨格をもつポリペプチドの翻訳合成とその応用
JP5605602B2 (ja) 2007-03-26 2014-10-15 国立大学法人 東京大学 環状ペプチド化合物の合成方法
JP5920835B2 (ja) 2010-12-01 2016-05-18 田辺三菱製薬株式会社 無細胞翻訳系でＦａｂを提示しうるポリヌクレオチド構築物ならびにそれを用いたＦａｂの製造方法およびスクリーニング方法
JP5948673B2 (ja) 2011-03-10 2016-07-06 ジーンフロンティア株式会社 リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639595A (en) * 1990-05-01 1997-06-17 Isis Phamaceuticals, Inc. Identification of novel drugs and reagents
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5998142A (en) 1993-09-08 1999-12-07 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US6063566A (en) 1994-05-13 2000-05-16 The Scripps Research Institute Catalytic RNA molecules
ES2127106B1 (es) 1996-03-21 1999-11-16 Menarini Lab Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos.
US5792613A (en) * 1996-06-12 1998-08-11 The Curators Of The University Of Missouri Method for obtaining RNA aptamers based on shape selection
US5871924A (en) 1997-01-27 1999-02-16 Nexstar Pharmaceuticals, Inc. Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis
DE19801153A1 (de) 1998-01-14 1999-07-15 Jenne Andreas Verfahren zur Selektion von Ribozymen, die Ribonucleinsäuren in trans an 2'-OH-Gruppen kovalent modifizieren können und durch dieses Verfahren erhältliche Ribozyme

Also Published As

Publication number Publication date
JP4745577B2 (ja) 2011-08-10
CA2391433C (en) 2011-02-08
DE60039120D1 (de) 2008-07-17
CA2391433A1 (en) 2001-05-31
US7001723B1 (en) 2006-02-21
AU1927601A (en) 2001-06-04
WO2001038582A1 (en) 2001-05-31
EP1232285A4 (de) 2005-01-12
EP1232285A1 (de) 2002-08-21
EP1232285B1 (de) 2008-06-04
JP2003514572A (ja) 2003-04-22

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