ATE398288T1 - Hoch-durchsatz prion tests - Google Patents

Hoch-durchsatz prion tests

Info

Publication number
ATE398288T1
ATE398288T1 AT06006458T AT06006458T ATE398288T1 AT E398288 T1 ATE398288 T1 AT E398288T1 AT 06006458 T AT06006458 T AT 06006458T AT 06006458 T AT06006458 T AT 06006458T AT E398288 T1 ATE398288 T1 AT E398288T1
Authority
AT
Austria
Prior art keywords
sample
prpsc
followed
analysis
specific detection
Prior art date
Application number
AT06006458T
Other languages
English (en)
Inventor
Walter Eberle
Werner Stock
Baerbel Winter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE398288T1 publication Critical patent/ATE398288T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT06006458T 2004-11-15 2005-11-14 Hoch-durchsatz prion tests ATE398288T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04027088 2004-11-15

Publications (1)

Publication Number Publication Date
ATE398288T1 true ATE398288T1 (de) 2008-07-15

Family

ID=34927388

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06006457T ATE389182T1 (de) 2004-11-15 2005-11-14 Prion-assays mit hoher durchlaufleistung
AT06006458T ATE398288T1 (de) 2004-11-15 2005-11-14 Hoch-durchsatz prion tests

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06006457T ATE389182T1 (de) 2004-11-15 2005-11-14 Prion-assays mit hoher durchlaufleistung

Country Status (5)

Country Link
US (1) US7741054B2 (de)
EP (3) EP1677114A1 (de)
AT (2) ATE389182T1 (de)
CA (1) CA2523745C (de)
DE (2) DE602005007458D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084201A1 (en) 2009-01-26 2010-07-29 Commissariat A L'energie Atomique Et Aux Energies Alternatives Novel derivative of erythromycin for the treatment and diagnosis of prion disease
CN103344760B (zh) * 2013-07-23 2015-08-26 成都安铂奥金生物科技有限公司 一种高通量免疫组化检测方法及多样品免疫组化检测板
EP2842962A1 (de) * 2013-08-30 2015-03-04 Ludwig-Maximilians-Universität München Verfahren zur Isolierung eines rekombinanten Prionproteins und Verwendung davon
EP3399034B1 (de) * 2017-05-05 2022-12-28 Siemens Healthcare Diagnostics Inc. Vorrichtung zur extraktion von nukleinsäuren aus biologischen probenmaterialien mit lösungsmittelfreien reagenzien

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2208511A (en) * 1987-08-07 1989-04-05 Bayer Ag Variants of bovine pancreatic trypsin inhibitor produced by recombinant dna technology
JP2848840B2 (ja) * 1989-03-03 1999-01-20 国際試薬株式会社 Ｇｏｔアイソザイムの分別定量法
DE19730132C2 (de) * 1997-07-14 2000-01-20 Fraunhofer Ges Forschung Verfahren zum Nachweis von Prionen sowie eine Vorrichtung hierzu
DE10107083C2 (de) * 2001-02-13 2003-02-20 Abdulgabar Salama Pentosan Polysulfat als Ligand zum Nachweis von Prionen
DE10119713A1 (de) * 2001-04-21 2002-10-24 Prionics Ag Zuerich Verfahren zur Untersuchung von Prion-Protein enthaltenden Proben auf das eventuelle Vorliegen der PrPSc-Form
DE60212836T2 (de) * 2001-05-16 2007-01-25 Gpc Biotech Ag Pyridylpyrimidin-derivate als wirksame verbindungen gegen prionen-krankheiten
WO2003001211A1 (en) * 2001-06-22 2003-01-03 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for testing the presence of prion proteins in tissue and culture samples
AU2002352042A1 (en) * 2002-11-18 2004-06-15 Prionics Ag Method for the detection of prpsc

Also Published As

Publication number Publication date
DE602005005284D1 (de) 2008-04-24
CA2523745C (en) 2011-08-09
EP1677115A3 (de) 2006-09-20
DE602005007458D1 (de) 2008-07-24
US7741054B2 (en) 2010-06-22
DE602005005284T2 (de) 2009-04-16
EP1677115A2 (de) 2006-07-05
EP1674870A3 (de) 2006-09-20
EP1674870B1 (de) 2008-06-11
EP1677115B1 (de) 2008-03-12
CA2523745A1 (en) 2006-05-15
US20060121507A1 (en) 2006-06-08
EP1677114A1 (de) 2006-07-05
ATE389182T1 (de) 2008-03-15
EP1674870A2 (de) 2006-06-28

Similar Documents

Publication Publication Date Title
DE60028040D1 (de) Annexin-proteine und auto-antikörper als serummarker für lungenkrebs und ösophaguskrebs
ATE246378T1 (de) Verfahren zum feststellen der preparationsgüte von objektträgern und proben
WO2010021822A3 (en) Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites
WO2004097903A3 (en) Single tool defect classification solution
ATE394680T1 (de) Verfahren und vorrichtung zur charakterisierung von analyten
WO2005086647A3 (en) Immuno-pcr method for the detection of a biomolecule in a test sample
ATE536553T1 (de) Verfahren zum nachweis grösserer ungünstiger kardiovaskulärer und zerebrovaskulärer ereignisse
WO2008063663A3 (en) Poly (ethylene glycol) anti-body detection assays and kits for performing thereof
ATE370414T1 (de) Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
TW200801515A (en) Alzheimer's disease-specific alterations of the ERK1/ERK2 phosphorylation ratio- alzheimer's disease-specific molecular biomarkers (ADSMB)
WO2011037827A3 (en) Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
RU2011140006A (ru) Способ детекции вещества в биологическом образце
ATE398288T1 (de) Hoch-durchsatz prion tests
DE602005017016D1 (de) Verfahren zur beurteilung der gefahr und veranlagung, eine mit dem vorliegen von anti-epcr-antikörpern verbundene symptomatik zu entwickeln
EP1560025A3 (de) Marker spezifisch für Diabetes
WO2002033420A3 (en) A urine test for the diagnosis of prion diseases
ATE532796T1 (de) Immunassays zur spezifischen bestimmung von scca- isoformen
JP6017724B1 (ja) 十二指腸液試料の膵液由来成分検出用試料としての適性評価方法
WO2020146719A8 (en) Co-assays to functional cancer biomarker assays
FR3089634B1 (fr) Methode pour la detection de la presence, l’identification et la quantification dans un echantillon sanguin d'anticoagulants inhibiteurs d’enzymes de la coagulation du sang, et moyens pour son implementation
TW200942819A (en) Alzheimer's disease-specific alterations of the ErK1/ErK2 phosphorylation ratio-alzheimer's disease-specific molecular biomarkers (ADSMB)
ATE534907T1 (de) Verfahren für den nachweis von l523s-expression in biologischen proben
MY200831A (en) A Biomarker for Detecting Strongyloides, Methods of Detecting Strongyloides and Diagnosing Strongyloidiasis in a Biological Sample, and a Diagnostic Kit Comprising Thereof
Cainé et al. Detection of semen in forensic samples
WO2005037056A3 (en) Method for the detection of a biomolecule in a test sample

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties