ATE398452T1 - 6-aryl-7-halo-imidazoä1,2-aüpyrimidine als mittel gegen krebs - Google Patents

6-aryl-7-halo-imidazoä1,2-aüpyrimidine als mittel gegen krebs

Info

Publication number: ATE398452T1
Authority: AT; Austria
Prior art keywords: halo; aryl; imidazoä1; aüpyrimidine; against cancer
Prior art date: 2003-09-24

Application number

AT04784454T

Other languages

English (en)

Inventor

Nan Zhang

Semiramis Ayral-Kaloustian

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-24

Filing date

2004-09-17

Publication date

2008-07-15

2004-09-17 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE398452T1 publication Critical patent/ATE398452T1/de

Links

206010028980 Neoplasm Diseases 0.000 title abstract 2
201000011510 cancer Diseases 0.000 title 1
241000124008 Mammalia Species 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT04784454T 2003-09-24 2004-09-17 6-aryl-7-halo-imidazoä1,2-aüpyrimidine als mittel gegen krebs ATE398452T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US50548603P	2003-09-24	2003-09-24

Publications (1)

Publication Number	Publication Date
ATE398452T1 true ATE398452T1 (de)	2008-07-15

Family

ID=34393021

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04784454T ATE398452T1 (de)	2003-09-24	2004-09-17	6-aryl-7-halo-imidazoä1,2-aüpyrimidine als mittel gegen krebs

Country Status (14)

Country	Link
US (2)	US7285555B2 (de)
EP (1)	EP1684763B1 (de)
JP (1)	JP4695595B2 (de)
CN (1)	CN100486580C (de)
AT (1)	ATE398452T1 (de)
AU (1)	AU2004275728A1 (de)
BR (1)	BRPI0414778A (de)
CA (1)	CA2537520A1 (de)
DE (1)	DE602004014525D1 (de)
DK (1)	DK1684763T3 (de)
ES (1)	ES2308256T3 (de)
MX (1)	MXPA06002939A (de)
PL (1)	PL1684763T3 (de)
WO (1)	WO2005030218A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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WO2000035422A2 (en) *	1998-12-18	2000-06-22	Hadasit Medical Research Services & Development Ltd.	Method of administering a compound to multi-drug resistant cells
DK2495016T3 (da)	2005-12-23	2019-12-16	Ariad Pharma Inc	Bicykliske heteroarylforbindelser
CN101600350A (zh) *	2007-01-08	2009-12-09	巴斯夫欧洲公司	唑并嘧啶在防治植物病原性有害真菌中的用途
CN107935870A (zh) *	2017-11-09	2018-04-20	华中药业股份有限公司	一种2‑甲氨基‑5‑氯二苯甲酮的合成方法

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JP2794510B2 (ja) *	1992-03-27	1998-09-10	富士写真フイルム株式会社	ハロゲン化銀写真感光材料
IL108747A (en) *	1993-03-04	1999-03-12	Shell Int Research	Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation
IL108731A (en) *	1993-03-04	1997-03-18	Shell Int Research	6, N-DISUBSTITUTED-£1, 2, 4\| TRIAZOLO-£1, 5-a\| PYRIMIDINE- 7-AMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
RU2147584C1 (ru) *	1995-10-27	2000-04-20	Американ Цианамид Компани	Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов
US5817663A (en) *	1996-10-07	1998-10-06	American Cyanamid Company	Pentafluorophenylazolopyrimidines
DE69810924T2 (de)	1997-03-18	2003-09-04	Basf Ag	Verfahren zur herstellung von arylmalonaten
US5750766A (en) *	1997-03-18	1998-05-12	American Cyanamid Company	Process for the preparation of arylmalonates
US5948783A (en) *	1997-04-14	1999-09-07	American Cyanamid Company	Fungicidal trifluoromethylalkylamino-triazolopyrimidines
TWI252231B (en)	1997-04-14	2006-04-01	American Cyanamid Co	Fungicidal trifluorophenyl-triazolopyrimidines
US6117876A (en) *	1997-04-14	2000-09-12	American Cyanamid Company	Fungicidal trifluorophenyl-triazolopyrimidines
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TW460476B (en)	1997-04-14	2001-10-21	American Cyanamid Co	Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US5994360A (en) *	1997-07-14	1999-11-30	American Cyanamid Company	Fungicidal 5-alkyl-triazolopyrimidines
US6020338A (en) *	1998-02-11	2000-02-01	American Cyanamid Company	Fungicidal 7-alkyl-triazolopyrimidines
KR100368102B1 (ko)	1998-02-11	2003-03-17	아메리칸사이아나미드컴파니	살진균성 7-알킬-트리아졸로피리미딘
US6124301A (en) *	1998-03-17	2000-09-26	American Cyanamid Company	Enhancement of the efficacy of triazolopyrimidines
JPH11322517A (ja)	1998-03-17	1999-11-24	American Cyanamid Co	トリアゾロピリミジン類の効力の増進
JP3747435B2 (ja)	1998-03-23	2006-02-22	ワイス・ホールディングズ・コーポレイション	殺菌剤６−（２−ハロ−４−アルコキシフェニル）−トリアゾロピリミジン
US5981534A (en) *	1998-09-25	1999-11-09	American Cyanamid Company	Fungicidal 6-(2,6-difluoro-4-alkoxyphenyl)-triazolopyrimidines
US6284762B1 (en) *	1998-03-23	2001-09-04	American Cyanamid Company	Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
US6268371B1 (en) *	1998-09-10	2001-07-31	American Cyanamid Co.	Fungicidal mixtures
US6117865A (en) *	1998-09-10	2000-09-12	American Cyanamid Company	Fungicidal trifluorophenyl-triazolopyrimidines
US6156925A (en) *	1998-09-25	2000-12-05	American Cyanamid Company	Process for the preparation of halogenated phenylmaloates
US5986135A (en) *	1998-09-25	1999-11-16	American Cyanamid Company	Fungicidal trifluoromethylalkylamino-triazolopyrimidines
DK1130962T3 (da)	1998-09-25	2004-05-17	Basf Ag	Ikke-vandigt suspensionskoncentrat
US6242451B1 (en) *	1998-09-25	2001-06-05	Klaus-Juergen Pees	Fungicidal trihalophenyl-triazolopyrimidines
US5985883A (en) *	1998-09-25	1999-11-16	American Cyanamid Company	Fungicidal trichlorophenyl-triazolopyrimidines
JP2000103790A (ja)	1998-09-25	2000-04-11	American Cyanamid Co	殺菌・殺カビ性のトリハロフェニル―トリアゾロピリミジン類
ES2203021T3 (es)	1998-09-25	2004-04-01	Basf Aktiengesellschaft	Mezclas fungicidas.
US6277856B1 (en) *	1998-09-25	2001-08-21	American Cynamid Co.	Fungicidal mixtures
JP4025468B2 (ja)	1999-07-29	2007-12-19	三井化学株式会社	有機電界発光素子
WO2001035738A2 (en)	1999-11-18	2001-05-25	Basf Corporation	Non-aqueous concentrated spreading oil composition
US6559151B2 (en) *	2000-05-08	2003-05-06	Basf Aktiengesellschaft	6-(2-trifluoromethyl-phenyl)-triazolopyrimidines
NZ523807A (en) *	2000-06-30	2004-09-24	Wyeth Corp	Substituted-triazolopyrimidines as anticancer agents
SK3522003A3 (en) *	2000-08-25	2003-08-05	Basf Ag	Fungicidal formulation
PT1341794E (pt)	2000-12-06	2004-11-30	Wyeth Corp	6-(trifluorometil-fenil)-triazolopirimidinas fungicidas
WO2002067679A1 (en)	2001-02-19	2002-09-06	Basf Aktiengesellschaft	Fungicidal mixtures
US7105664B2 (en)	2001-04-11	2006-09-12	Basf Aktiengesellschaft	5-Halogen-6-phenyl-7-fluoroalkylamino-triazolopyrimidines as fungicides
EP1431299B1 (de)	2001-09-04	2007-05-23	Sumitomo Chemical Company, Limited	IMIDAZO(1,2-a)PYRIMIDINE UND DIESE ENTHALTENDE FUNGIZIDZUSAMMENSETZUNGEN
AU2003211651A1 (en) *	2002-04-19	2003-11-03	Sumitomo Chemical Company, Limited	5,6-DIPHENYLIMIDAZO(1,2-a)PYRIMIDINE AND BACTERICIDAL COMPOSITION CONTAINING THE SAME

2004
- 2004-09-17 WO PCT/US2004/030595 patent/WO2005030218A1/en not_active Ceased
- 2004-09-17 AT AT04784454T patent/ATE398452T1/de not_active IP Right Cessation
- 2004-09-17 MX MXPA06002939A patent/MXPA06002939A/es active IP Right Grant
- 2004-09-17 CN CNB2004800273126A patent/CN100486580C/zh not_active Expired - Fee Related
- 2004-09-17 EP EP04784454A patent/EP1684763B1/de not_active Expired - Lifetime
- 2004-09-17 AU AU2004275728A patent/AU2004275728A1/en not_active Withdrawn
- 2004-09-17 CA CA002537520A patent/CA2537520A1/en not_active Abandoned
- 2004-09-17 BR BRPI0414778-2A patent/BRPI0414778A/pt not_active IP Right Cessation
- 2004-09-17 ES ES04784454T patent/ES2308256T3/es not_active Expired - Lifetime
- 2004-09-17 DK DK04784454T patent/DK1684763T3/da active
- 2004-09-17 PL PL04784454T patent/PL1684763T3/pl unknown
- 2004-09-17 DE DE602004014525T patent/DE602004014525D1/de not_active Expired - Lifetime
- 2004-09-17 JP JP2006528080A patent/JP4695595B2/ja not_active Expired - Fee Related
- 2004-09-24 US US10/950,542 patent/US7285555B2/en not_active Expired - Fee Related
2007
- 2007-09-19 US US11/903,100 patent/US7915266B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20080255157A1 (en)	2008-10-16
CN100486580C (zh)	2009-05-13
JP4695595B2 (ja)	2011-06-08
CN1856311A (zh)	2006-11-01
CA2537520A1 (en)	2005-04-07
BRPI0414778A (pt)	2006-11-21
MXPA06002939A (es)	2006-05-31
ES2308256T3 (es)	2008-12-01
JP2007506745A (ja)	2007-03-22
AU2004275728A1 (en)	2005-04-07
EP1684763A1 (de)	2006-08-02
WO2005030218A1 (en)	2005-04-07
US20050065167A1 (en)	2005-03-24
US7285555B2 (en)	2007-10-23
DK1684763T3 (da)	2008-09-01
PL1684763T3 (pl)	2008-11-28
DE602004014525D1 (de)	2008-07-31
EP1684763B1 (de)	2008-06-18
US7915266B2 (en)	2011-03-29

Legal Events

Date	Code	Title	Description
2008-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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