ATE398456T1 - Verwendung von negativ-geladenen phospholipiden zur herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration - Google Patents
Verwendung von negativ-geladenen phospholipiden zur herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegenerationInfo
- Publication number
- ATE398456T1 ATE398456T1 AT02754804T AT02754804T ATE398456T1 AT E398456 T1 ATE398456 T1 AT E398456T1 AT 02754804 T AT02754804 T AT 02754804T AT 02754804 T AT02754804 T AT 02754804T AT E398456 T1 ATE398456 T1 AT E398456T1
- Authority
- AT
- Austria
- Prior art keywords
- negatively charged
- macular degeneration
- phospholipides
- medication
- prevention
- Prior art date
Links
- 208000002780 macular degeneration Diseases 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 150000003904 phospholipids Chemical class 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 2
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- 235000021466 carotenoid Nutrition 0.000 abstract 2
- 150000001747 carotenoids Chemical class 0.000 abstract 2
- ZGSPNIOCEDOHGS-UHFFFAOYSA-L disodium [3-[2,3-di(octadeca-9,12-dienoyloxy)propoxy-oxidophosphoryl]oxy-2-hydroxypropyl] 2,3-di(octadeca-9,12-dienoyloxy)propyl phosphate Chemical compound [Na+].[Na+].CCCCCC=CCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COP([O-])(=O)OCC(O)COP([O-])(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COC(=O)CCCCCCCC=CCC=CCCCCC ZGSPNIOCEDOHGS-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10141018A DE10141018A1 (de) | 2001-08-22 | 2001-08-22 | Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE398456T1 true ATE398456T1 (de) | 2008-07-15 |
Family
ID=7696167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02754804T ATE398456T1 (de) | 2001-08-22 | 2002-07-01 | Verwendung von negativ-geladenen phospholipiden zur herstellung eines medikaments zur behandlung und/oder vorbeugung von makuladegeneration |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030050283A1 (de) |
| EP (1) | EP1418922B1 (de) |
| JP (1) | JP2005501109A (de) |
| AT (1) | ATE398456T1 (de) |
| CA (1) | CA2458132A1 (de) |
| DE (2) | DE10141018A1 (de) |
| WO (1) | WO2003018028A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7470659B2 (en) * | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| WO2006034556A1 (en) * | 2004-09-29 | 2006-04-06 | Michael Ary Bos | Caratenoid composition and method for preparation thereof |
| WO2006091796A2 (en) * | 2005-02-22 | 2006-08-31 | Acucela, Inc. | Compositions and methods for diagnosing and treating retinal diseases |
| US20090155381A1 (en) * | 2005-09-08 | 2009-06-18 | Regina Goralczyc | Method of treatment or prevention of age-related macular degeneration |
| US20070071805A1 (en) * | 2005-09-26 | 2007-03-29 | Vasogen Ireland Ltd. | Treatment of inflammation and vascular abnormalities of the eye |
| US20070254832A1 (en) * | 2006-02-17 | 2007-11-01 | Pressler Milton L | Methods for the treatment of macular degeneration and related eye conditions |
| WO2007096744A1 (en) * | 2006-02-21 | 2007-08-30 | Pfizer Products Inc. | Methods for the treatment of macular degeneration and related eye conditions |
| CA2681850C (en) * | 2007-04-20 | 2013-07-23 | Acucela Inc. | Styrenyl derivative compounds for treating ophthalmic diseases and disorders |
| RU2470910C9 (ru) | 2007-06-29 | 2013-05-20 | Акьюсела, Инк. | Соединения, представляющие собой алкинилфенильные производные, для лечения офтальмических заболеваний и расстройств |
| CN103553945B (zh) | 2007-10-05 | 2015-01-07 | 奥克塞拉有限公司 | 用于治疗疾病的烷氧基化合物 |
| US20090312438A1 (en) * | 2008-06-13 | 2009-12-17 | Bernstein Paul S | Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium |
| EP2804605A4 (de) | 2012-01-20 | 2015-07-08 | Acucela Inc | Substituierte heterocyclische verbindungen zur behandlung von krankheiten |
| CA2903483A1 (en) | 2013-03-12 | 2014-10-09 | Acucela Inc. | Substituted 3-phenylpropylamine derivatives for the treatment of ophthalmic diseases and disorders |
| MX388028B (es) * | 2014-08-11 | 2025-03-19 | Univ Louisiana State | Suministro de antioxidantes bioactivos, nanoencapsulados. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4914088A (en) * | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
| KR920700691A (ko) * | 1989-04-04 | 1992-08-10 | 존.에프.맥인티리 | 상처부위, 절개부위, 찰과상 부위에 치료제의 투여에 대한 리포좀(liposomes)의 용도 |
| EP0459148B1 (de) * | 1990-05-29 | 1996-01-03 | Ocular Research Of Boston Inc. | Zusammensetzung zur Behandlung von Dry Eye Erkrankungen |
| EP0531933B1 (de) * | 1991-09-09 | 1997-07-09 | Canon Kabushiki Kaisha | Quantitativer Nachweis vom Lipid |
| GB2301775B (en) * | 1995-06-07 | 1999-08-04 | Howard Foundation | Treatment of age-related macular degeneration with carotenoids |
| US6075058A (en) * | 1998-12-12 | 2000-06-13 | Tufts University | Compositions for increased bioavailability of carotenoids |
-
2001
- 2001-08-22 DE DE10141018A patent/DE10141018A1/de not_active Ceased
-
2002
- 2002-07-01 DE DE60227178T patent/DE60227178D1/de not_active Expired - Lifetime
- 2002-07-01 JP JP2003522546A patent/JP2005501109A/ja active Pending
- 2002-07-01 WO PCT/EP2002/007237 patent/WO2003018028A1/en not_active Ceased
- 2002-07-01 CA CA002458132A patent/CA2458132A1/en not_active Abandoned
- 2002-07-01 AT AT02754804T patent/ATE398456T1/de not_active IP Right Cessation
- 2002-07-01 US US10/186,849 patent/US20030050283A1/en not_active Abandoned
- 2002-07-01 EP EP02754804A patent/EP1418922B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1418922B1 (de) | 2008-06-18 |
| WO2003018028A1 (en) | 2003-03-06 |
| DE10141018A1 (de) | 2003-03-13 |
| CA2458132A1 (en) | 2003-03-06 |
| US20030050283A1 (en) | 2003-03-13 |
| JP2005501109A (ja) | 2005-01-13 |
| DE60227178D1 (de) | 2008-07-31 |
| EP1418922A1 (de) | 2004-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |