ATE497391T1 - Verfahren zur behandlung von postoperativen schmerzen durch verabreichung eines antikörpers gegen nervenwachstumsfaktor und diesen enthaltende zusammensetzungen - Google Patents
Verfahren zur behandlung von postoperativen schmerzen durch verabreichung eines antikörpers gegen nervenwachstumsfaktor und diesen enthaltende zusammensetzungenInfo
- Publication number
- ATE497391T1 ATE497391T1 AT03779091T AT03779091T ATE497391T1 AT E497391 T1 ATE497391 T1 AT E497391T1 AT 03779091 T AT03779091 T AT 03779091T AT 03779091 T AT03779091 T AT 03779091T AT E497391 T1 ATE497391 T1 AT E497391T1
- Authority
- AT
- Austria
- Prior art keywords
- antibody
- growth factor
- nerve growth
- administration
- same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Surgery (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41723702P | 2002-10-08 | 2002-10-08 | |
| PCT/US2003/032089 WO2004032870A2 (en) | 2002-10-08 | 2003-10-08 | Methods for treating post-surgical pain by admisnistering a nerve growth factor antagonist and compositions containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE497391T1 true ATE497391T1 (de) | 2011-02-15 |
Family
ID=32093988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03779091T ATE497391T1 (de) | 2002-10-08 | 2003-10-08 | Verfahren zur behandlung von postoperativen schmerzen durch verabreichung eines antikörpers gegen nervenwachstumsfaktor und diesen enthaltende zusammensetzungen |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7252822B2 (de) |
| EP (1) | EP1556083B1 (de) |
| JP (1) | JP4584713B2 (de) |
| KR (1) | KR101080716B1 (de) |
| CN (1) | CN1723039B (de) |
| AT (1) | ATE497391T1 (de) |
| AU (1) | AU2003285864C1 (de) |
| BR (1) | BR0315164A (de) |
| CA (1) | CA2501626A1 (de) |
| DE (1) | DE60335957D1 (de) |
| DK (1) | DK1556083T3 (de) |
| ES (1) | ES2357948T3 (de) |
| IL (1) | IL167654A (de) |
| MX (1) | MXPA05003502A (de) |
| NO (1) | NO20052219L (de) |
| NZ (1) | NZ539101A (de) |
| PL (1) | PL211654B1 (de) |
| PT (1) | PT1556083E (de) |
| RU (1) | RU2338555C2 (de) |
| SI (1) | SI1556083T1 (de) |
| UA (1) | UA89610C2 (de) |
| WO (1) | WO2004032870A2 (de) |
| ZA (1) | ZA200502612B (de) |
Families Citing this family (68)
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| US6703047B2 (en) * | 2001-02-02 | 2004-03-09 | Incept Llc | Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use |
| UA80447C2 (en) * | 2002-10-08 | 2007-09-25 | Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic | |
| AU2003304238A1 (en) | 2002-10-08 | 2005-01-13 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same |
| PL211654B1 (pl) | 2002-10-08 | 2012-06-29 | Rinat Neuroscience Corp | Przeciwciało skierowane przeciwko NGF do zastosowania w leczeniu bólu pooperacyjnego, zastosowanie tego przeciwciała do wytwarzania leku do leczenia bólu pooperacyjnego i kompozycja farmaceutyczna zawierająca przeciwciało skierowane przeciwko NGF do zastosowania w leczeniu bólu pooperacyjnego |
| US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
| SI1575517T1 (sl) | 2002-12-24 | 2012-06-29 | Rinat Neuroscience Corp | Protitelesa proti ĺ˝iväśnemu rastnemu dejavniku in metode njihove uporabe |
| US7569364B2 (en) * | 2002-12-24 | 2009-08-04 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
| DE602004030535D1 (de) | 2003-02-19 | 2011-01-27 | Rinat Neuroscience Corp | Verfahren zur behandlung von schmerzen durch verabreichung eines nervenwachstumsfaktor-antagonisten und eines nsaid und diese enthaltende zusammensetzung |
| CN100581621C (zh) * | 2003-05-16 | 2010-01-20 | 拉瓦勒大学 | Cns氯化物调节及其用途 |
| RS20100555A (sr) | 2003-07-15 | 2011-08-31 | Amgen Inc. | Humana anti-ngf neutrališuća antitela kao selektivni inhibitori ngf signalnog puta |
| ITRM20030601A1 (it) | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti. |
| EP1732949B1 (de) | 2004-04-07 | 2010-01-27 | Rinat Neuroscience Corp. | Verfahren zur schmerzbehandlung in knochenkrebs durch verabreichung eines ngf-antagonisten |
| WO2005110490A1 (en) | 2004-05-14 | 2005-11-24 | Universite Laval | Phospholipase c gamma modulation and uses thereof for management of pain and nociception |
| ME00226B (me) | 2004-07-15 | 2011-02-10 | Medarex Llc | Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade |
| KR101298383B1 (ko) | 2005-01-24 | 2013-08-20 | 엘란 파마 인터내셔널 리미티드 | Ngf에 대한 특이적 결합 멤버 |
| ITRM20050290A1 (it) * | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
| WO2007035906A2 (en) | 2005-09-21 | 2007-03-29 | The Regents Of The University Of California | Systems and methods for imaging-treatment of pain |
| US9789161B2 (en) * | 2006-04-28 | 2017-10-17 | Warsaw Orthopedic, Inc. | Methods for treating back or neck pain caused by NGF using a therapeutic agent consisting of ReN-1820, ALE-0540 and capsaicin |
| AU2008218925A1 (en) | 2007-02-20 | 2008-08-28 | Anaptysbio, Inc. | Somatic hypermutation systems |
| EP2187964B1 (de) | 2007-08-10 | 2014-10-08 | Regeneron Pharmaceuticals, Inc. | Hochaffine humane antikörper gegen den humanen nervenwachstumsfaktor |
| US8309088B2 (en) | 2007-08-10 | 2012-11-13 | Regeneron Pharmaceuticals, Inc. | Method of treating osteoarthritis with an antibody to NGF |
| CA2709135C (en) * | 2007-12-17 | 2018-06-05 | Pfizer Limited | Treatment of interstitial cystitis |
| CA2713786A1 (en) | 2008-02-04 | 2009-08-13 | Lay Line Genomics S.P.A. | Anti-trka antibodies and antigen-binding derivatives thereof |
| US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
| WO2009150623A1 (en) * | 2008-06-13 | 2009-12-17 | Pfizer Inc | Treatment of chronic prostatitis |
| WO2010032220A1 (en) * | 2008-09-19 | 2010-03-25 | Pfizer Inc. | Stable liquid antibody formulation |
| EP2354225B1 (de) | 2008-09-24 | 2015-04-22 | Ribomic Inc. | Aptamer für ngf und verwendung davon |
| JP5752601B2 (ja) | 2008-12-08 | 2015-07-22 | ブイエム ファーマ エルエルシー | タンパク質受容体チロシンキナーゼ阻害薬の組成物 |
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| SG175436A1 (en) | 2009-05-04 | 2011-12-29 | Abbott Res Bv | Antibodies against nerve growth factor (ngf) with enhanced in vivo stability |
| KR20190047135A (ko) | 2010-03-01 | 2019-05-07 | 바이엘 헬스케어 엘엘씨 | 조직 인자 경로 억제제 (tfpi)에 대한 최적화된 모노클로날 항체 |
| TW201201835A (en) | 2010-03-17 | 2012-01-16 | Abbott Res Bv | Anti-nerve growth factor (NGF) antibody compositions |
| CA2794199C (en) | 2010-03-24 | 2017-11-14 | Shionogi & Co., Ltd. | Aptamer for ngf and use thereof |
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| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9783601B2 (en) * | 2010-12-01 | 2017-10-10 | Alderbio Holdings Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
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| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| BR112013029201B1 (pt) | 2011-05-13 | 2022-08-09 | Array Biopharma Inc | Compostos de pirrolidinil ureia e pirrolidinil tioureia, seu processo de preparação, seu uso e composições farmacêuticas |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| US8926978B2 (en) | 2011-10-25 | 2015-01-06 | Anaptysbio, Inc. | Antibodies directed against nerve growth factor (NGF) |
| JP2015503592A (ja) * | 2012-01-05 | 2015-02-02 | ビーチ ツリー ラボ、インコーポレイテッド | 神経成長因子の投与による疼痛処置方法 |
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| US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
| US8613919B1 (en) | 2012-08-31 | 2013-12-24 | Bayer Healthcare, Llc | High concentration antibody and protein formulations |
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| WO2014078322A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| CN104781255B (zh) | 2012-11-13 | 2017-10-24 | 阵列生物制药公司 | 作为trka激酶抑制剂的n‑吡咯烷基、n’‑吡唑基‑脲、硫脲、胍和氰基胍化合物 |
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