ATE398457T1 - Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor - Google Patents

Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor

Info

Publication number
ATE398457T1
ATE398457T1 AT03075776T AT03075776T ATE398457T1 AT E398457 T1 ATE398457 T1 AT E398457T1 AT 03075776 T AT03075776 T AT 03075776T AT 03075776 T AT03075776 T AT 03075776T AT E398457 T1 ATE398457 T1 AT E398457T1
Authority
AT
Austria
Prior art keywords
topoisomerase
inhibitor
preparation containing
combination preparation
anthracycline derivative
Prior art date
Application number
AT03075776T
Other languages
English (en)
Inventor
Maria Cristina Geroni
Marina Ripamonti
Michele Caruso
Antonio Suarato
Original Assignee
Nerviano Medical Sciences Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences Srl filed Critical Nerviano Medical Sciences Srl
Application granted granted Critical
Publication of ATE398457T1 publication Critical patent/ATE398457T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03075776T 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor ATE398457T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9909925.1A GB9909925D0 (en) 1999-04-29 1999-04-29 Combined preparations comprising anthracycline derivatives

Publications (1)

Publication Number Publication Date
ATE398457T1 true ATE398457T1 (de) 2008-07-15

Family

ID=10852508

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03075776T ATE398457T1 (de) 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor
AT00925158T ATE246507T1 (de) 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00925158T ATE246507T1 (de) 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Country Status (16)

Country Link
US (2) US6537990B1 (de)
EP (3) EP1977753A1 (de)
JP (1) JP2002543112A (de)
CN (5) CN1222294C (de)
AR (1) AR023616A1 (de)
AT (2) ATE398457T1 (de)
AU (1) AU4397700A (de)
DE (2) DE60004348T2 (de)
DK (1) DK1173187T3 (de)
ES (2) ES2307867T3 (de)
GB (1) GB9909925D0 (de)
HK (1) HK1045462B (de)
MY (1) MY136610A (de)
PT (1) PT1173187E (de)
TW (1) TWI222863B (de)
WO (1) WO2000066093A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916882D0 (en) * 1999-07-19 1999-09-22 Pharmacia & Upjohn Spa Antitumor synergistic composition
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
US20030133939A1 (en) * 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
ATE554756T1 (de) * 2001-03-14 2012-05-15 Bristol Myers Squibb Co Kombination aus epothilon-analog und chemotherapeutika zur behandlung von proliferativen erkrankungen
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20080075762A1 (en) * 2001-10-03 2008-03-27 Paul Tardi Compositions for delivery of drug combinations
WO2003061566A2 (en) * 2002-01-24 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anti-cancer combination and use thereof
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
JP2006519209A (ja) * 2003-02-26 2006-08-24 ファルマシア・イタリア・ソシエタ・ペル・アツィオーニ ネモルビシン（ｎｅｍｏｒｕｂｉｃｉｎ）の肝臓内投与により肝臓癌を治療するための方法
MXPA05009849A (es) * 2003-03-18 2005-12-06 Pharmacia Italia Spa Terapia combinada que comprende nemorubicina y un inhibidor de la ciclooxigenasa-2.
CN100500212C (zh) * 2005-04-06 2009-06-17 山东蓝金生物工程有限公司 一种抗实体肿瘤药物组合物
AU2006272555B2 (en) 2005-07-25 2012-03-08 Aptevo Research And Development Llc B-cell reduction using CD37-specific and CD20-specific binding molecules
US7776832B2 (en) * 2006-04-21 2010-08-17 Gem Pharmaceuticals, Llc Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines
CN105837690A (zh) 2006-06-12 2016-08-10 新兴产品开发西雅图有限公司 具有效应功能的单链多价结合蛋白
US20090004134A1 (en) * 2006-09-08 2009-01-01 Obeid Michel Sarkis Kit for treating a health condition by inducing translocation of an erp57 protein to a cellular membrane
EP2109462A1 (de) * 2007-01-29 2009-10-21 Nerviano Medical Sciences S.r.l. Antitumor-kombination mit einem morpholinyl-anthracyclin und einem antikörper
US8940334B2 (en) 2007-05-11 2015-01-27 Nerviano Medical Sciences S.R.L. Pharmaceutical composition of an anthracycline
US20110021517A1 (en) * 2008-02-26 2011-01-27 Nerviano Medical Sciences S.R.L. Antitumor combination comprising a morpholinyl anthracycline derivative and demethylating agents
NZ603059A (en) * 2008-04-11 2014-07-25 Emergent Product Dev Seattle Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
KR20170110083A (ko) 2014-12-23 2017-10-10 인털렉츄얼 프라퍼티 어쏘시에이츠, 엘엘씨 경피 투여를 위한 방법 및 제형
HK1251480A1 (zh) 2015-09-21 2019-02-01 Aptevo Research And Development Llc Cd3结合多肽
EP4324460A3 (de) 2017-09-15 2024-04-24 Dyve Biosciences, Inc. Natriumhydrogencarbonat zur verwendung in der behandlung von gicht und verwandten erkrankungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
US5902809A (en) * 1997-07-03 1999-05-11 Paracure, Inc. Arglabin compounds and therapeutic uses thereof
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9820012D0 (en) * 1998-09-14 1998-11-04 Pharmacia & Upjohn Spa Use of an anthracycline derivative for the treatment of a liver tumor

Also Published As

Publication number Publication date
CN1507869A (zh) 2004-06-30
HK1045462B (zh) 2006-04-28
CN1853645A (zh) 2006-11-01
EP1977753A1 (de) 2008-10-08
WO2000066093A2 (en) 2000-11-09
AR023616A1 (es) 2002-09-04
DK1173187T3 (da) 2003-10-20
ES2307867T3 (es) 2008-12-01
US20030087839A1 (en) 2003-05-08
EP1323423B1 (de) 2008-06-18
JP2002543112A (ja) 2002-12-17
MY136610A (en) 2008-10-31
US6537990B1 (en) 2003-03-25
ATE246507T1 (de) 2003-08-15
EP1323423A1 (de) 2003-07-02
CN1853642A (zh) 2006-11-01
GB9909925D0 (en) 1999-06-30
AU4397700A (en) 2000-11-17
DE60039260D1 (de) 2008-07-31
ES2204572T3 (es) 2004-05-01
CN1535688A (zh) 2004-10-13
TWI222863B (en) 2004-11-01
PT1173187E (pt) 2003-10-31
DE60004348T2 (de) 2004-02-26
DE60004348D1 (de) 2003-09-11
US6586428B2 (en) 2003-07-01
CN1349406A (zh) 2002-05-15
EP1173187A2 (de) 2002-01-23
HK1045462A1 (en) 2002-11-29
CN1222294C (zh) 2005-10-12
WO2000066093A3 (en) 2001-01-25
EP1173187B1 (de) 2003-08-06

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