ATE398629T1 - Verfahren zur herstellung einer phytosterolzusammensetzung - Google Patents
Verfahren zur herstellung einer phytosterolzusammensetzungInfo
- Publication number
- ATE398629T1 ATE398629T1 AT00922365T AT00922365T ATE398629T1 AT E398629 T1 ATE398629 T1 AT E398629T1 AT 00922365 T AT00922365 T AT 00922365T AT 00922365 T AT00922365 T AT 00922365T AT E398629 T1 ATE398629 T1 AT E398629T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrocarbon
- phytosterols
- complex
- metal salt
- producing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 3
- 229930195733 hydrocarbon Natural products 0.000 abstract 3
- 150000002430 hydrocarbons Chemical class 0.000 abstract 3
- 229940068065 phytosterols Drugs 0.000 abstract 3
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 abstract 1
- VGSSUFQMXBFFTM-UHFFFAOYSA-N (24R)-24-ethyl-5alpha-cholestane-3beta,5,6beta-triol Natural products C1C(O)C2(O)CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 VGSSUFQMXBFFTM-UHFFFAOYSA-N 0.000 abstract 1
- ARYTXMNEANMLMU-UHFFFAOYSA-N 24alpha-methylcholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(C)C(C)C)C1(C)CC2 ARYTXMNEANMLMU-UHFFFAOYSA-N 0.000 abstract 1
- OILXMJHPFNGGTO-NRHJOKMGSA-N Brassicasterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@](C)([C@H]([C@@H](/C=C/[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 OILXMJHPFNGGTO-NRHJOKMGSA-N 0.000 abstract 1
- SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 abstract 1
- BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 abstract 1
- LGJMUZUPVCAVPU-JFBKYFIKSA-N Sitostanol Natural products O[C@@H]1C[C@H]2[C@@](C)([C@@H]3[C@@H]([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)CC2)CC1 LGJMUZUPVCAVPU-JFBKYFIKSA-N 0.000 abstract 1
- OILXMJHPFNGGTO-ZRUUVFCLSA-N UNPD197407 Natural products C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)C=C[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZRUUVFCLSA-N 0.000 abstract 1
- 229940076810 beta sitosterol Drugs 0.000 abstract 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 abstract 1
- 235000004420 brassicasterol Nutrition 0.000 abstract 1
- OILXMJHPFNGGTO-ZAUYPBDWSA-N brassicasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZAUYPBDWSA-N 0.000 abstract 1
- ARYTXMNEANMLMU-ATEDBJNTSA-N campestanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]2(C)CC1 ARYTXMNEANMLMU-ATEDBJNTSA-N 0.000 abstract 1
- 235000000431 campesterol Nutrition 0.000 abstract 1
- SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 abstract 1
- 230000000536 complexating effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229950005143 sitosterol Drugs 0.000 abstract 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 abstract 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
- LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B13/00—Recovery of fats, fatty oils or fatty acids from waste materials
- C11B13/02—Recovery of fats, fatty oils or fatty acids from waste materials from soap stock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B13/00—Recovery of fats, fatty oils or fatty acids from waste materials
- C11B13/005—Recovery of fats, fatty oils or fatty acids from waste materials of residues of the fabrication of wood-cellulose (in particular tall-oil)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/74—Recovery of fats, fatty oils, fatty acids or other fatty substances, e.g. lanolin or waxes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30013599A | 1999-04-27 | 1999-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE398629T1 true ATE398629T1 (de) | 2008-07-15 |
Family
ID=23157859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00922365T ATE398629T1 (de) | 1999-04-27 | 2000-04-27 | Verfahren zur herstellung einer phytosterolzusammensetzung |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1173464B1 (de) |
| JP (1) | JP2002543088A (de) |
| AT (1) | ATE398629T1 (de) |
| AU (1) | AU4279400A (de) |
| BR (1) | BR0010062A (de) |
| CA (1) | CA2372154A1 (de) |
| CY (1) | CY1110390T1 (de) |
| DE (1) | DE60039232D1 (de) |
| DK (1) | DK1173464T3 (de) |
| ES (1) | ES2308979T3 (de) |
| PT (1) | PT1173464E (de) |
| SI (1) | SI1173464T1 (de) |
| WO (1) | WO2000064921A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001053320A2 (en) * | 2000-01-21 | 2001-07-26 | Forbes Medi-Tech Inc. | Crystalline composites comprising phytosterols and phytostanols or derivatives thereof |
| JP4707862B2 (ja) * | 2001-04-16 | 2011-06-22 | 花王株式会社 | 植物ステロールの製法 |
| CA2531312A1 (en) * | 2003-07-29 | 2005-02-17 | Unilever Plc | Food product comprising phytosterols |
| EP1568760A1 (de) * | 2004-02-06 | 2005-08-31 | Härting Glade, Thomas Francis | Verfahren zur Raffination eines Rohstoffs enthalten Schwarzlauge, Rohtallöl oder Tallpech |
| CA2717956C (en) | 2008-03-10 | 2017-01-10 | Sunpine Ab | Recovery of phytosterols from residual vegetable oil streams |
| JP5378001B2 (ja) * | 2009-02-17 | 2013-12-25 | 花王株式会社 | 脂肪酸アルキルエステルの精製方法 |
| JP5412301B2 (ja) * | 2009-02-17 | 2014-02-12 | 花王株式会社 | 植物油の精製・製造方法 |
| US10383886B2 (en) | 2010-01-11 | 2019-08-20 | Phoenix Biotechnology, Inc. | Method of treating neurological conditions with oleandrin |
| US9011937B2 (en) * | 2010-11-22 | 2015-04-21 | Phoenix Biotechnology, Inc. | Method of treating neurological conditions with extract of Nerium species or Thevetia species |
| US10307450B2 (en) | 2010-01-11 | 2019-06-04 | Phoenix Biotechnology, Inc. | Method of treating neurological conditions with extract of Nerium species or Thevetia species |
| US8039025B1 (en) | 2010-10-15 | 2011-10-18 | Life Plus, LLC | Methods and dosage forms for the treatment of human cancers |
| US10702567B2 (en) | 2016-09-14 | 2020-07-07 | Phoenix Biotechnology, Inc. | Method and compositions for treating viral infection |
| US10596186B2 (en) | 2016-09-14 | 2020-03-24 | Phoenix Biotechnology, Inc. | Method and compositions for treating viral infections |
| US10729735B1 (en) | 2016-09-14 | 2020-08-04 | Phoenix Biotechnology, Inc. | Method and compostitions for treating coronavirus infection |
| US11629309B2 (en) | 2017-09-14 | 2023-04-18 | Fermenta Biotech Limited | Solvent free process for extraction of cholesterol from milk fat |
| CN111417384A (zh) | 2017-09-14 | 2020-07-14 | 菲尼克斯生物技术公司 | 用于治疗神经系统病况的方法和改进的神经保护性组合物 |
| US11331291B2 (en) | 2017-09-14 | 2022-05-17 | Phoenix Biotechnology, Inc. | Method of and improved composition for treating triterpene-responsive conditions, diseases or disorders |
| CA3146266A1 (en) * | 2019-09-27 | 2021-04-01 | Basf Se | Process for the purification of phytosterol |
| US11806359B2 (en) | 2020-03-31 | 2023-11-07 | Phoenix Biotechnology, Inc. | Method and compositions for treating Coronavirus infection |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE827199C (de) * | 1948-02-09 | 1952-01-07 | Konink Veenendaalsche Sajeten | Verfahren zur Gewinnung von Sterinen |
| NL127423C (de) * | 1967-05-11 | |||
| US3840570A (en) * | 1970-12-07 | 1974-10-08 | Procter & Gamble | Process for preparing sterols from tall oil pitch |
| US4044031A (en) * | 1976-07-02 | 1977-08-23 | Ake Allan Johansson | Process for the separation of sterols |
| DE2656208A1 (de) * | 1976-12-11 | 1978-06-15 | Henkel Kgaa | Verfahren zur isolierung von sterinen aus fettverarbeitungsrueckstaenden |
| US4425275A (en) * | 1982-07-12 | 1984-01-10 | Eastman Kodak Company | Process for separating 3-hydroxy steroids or sterols from mixtures such as lipids |
| SK284250B6 (sk) * | 1994-09-29 | 2004-12-01 | The University Of British Columbia | Kompozícia znižujúca cholesterol, jej použitie a terapeuticky účinný produkt s jej obsahom |
-
2000
- 2000-04-27 ES ES00922365T patent/ES2308979T3/es not_active Expired - Lifetime
- 2000-04-27 AT AT00922365T patent/ATE398629T1/de not_active IP Right Cessation
- 2000-04-27 CA CA 2372154 patent/CA2372154A1/en not_active Abandoned
- 2000-04-27 DE DE60039232T patent/DE60039232D1/de not_active Expired - Lifetime
- 2000-04-27 PT PT00922365T patent/PT1173464E/pt unknown
- 2000-04-27 EP EP20000922365 patent/EP1173464B1/de not_active Expired - Lifetime
- 2000-04-27 SI SI200031006T patent/SI1173464T1/sl unknown
- 2000-04-27 BR BR0010062A patent/BR0010062A/pt not_active Application Discontinuation
- 2000-04-27 JP JP2000614270A patent/JP2002543088A/ja active Pending
- 2000-04-27 AU AU42794/00A patent/AU4279400A/en not_active Abandoned
- 2000-04-27 DK DK00922365T patent/DK1173464T3/da active
- 2000-04-27 WO PCT/CA2000/000455 patent/WO2000064921A2/en not_active Ceased
-
2008
- 2008-07-21 CY CY20081100754T patent/CY1110390T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000064921A2 (en) | 2000-11-02 |
| CY1110390T1 (el) | 2012-05-23 |
| WO2000064921A3 (en) | 2001-07-12 |
| CA2372154A1 (en) | 2000-11-02 |
| DK1173464T3 (da) | 2008-10-06 |
| AU4279400A (en) | 2000-11-10 |
| SI1173464T1 (sl) | 2009-02-28 |
| BR0010062A (pt) | 2002-05-21 |
| DE60039232D1 (de) | 2008-07-31 |
| JP2002543088A (ja) | 2002-12-17 |
| PT1173464E (pt) | 2008-08-05 |
| EP1173464A2 (de) | 2002-01-23 |
| ES2308979T3 (es) | 2008-12-16 |
| EP1173464B1 (de) | 2008-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1173464 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |