ATE398629T1 - Verfahren zur herstellung einer phytosterolzusammensetzung - Google Patents

Verfahren zur herstellung einer phytosterolzusammensetzung

Info

Publication number: ATE398629T1
Authority: AT; Austria
Prior art keywords: hydrocarbon; phytosterols; complex; metal salt; producing
Prior art date: 1999-04-27

Application number

AT00922365T

Other languages

English (en)

Inventor

James Coss

James Kutney

Radka Milanova

Paul Jollez

Original Assignee

Forbes Medi Tech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-27

Filing date

2000-04-27

Publication date

2008-07-15

2000-04-27 Application filed by Forbes Medi Tech Inc filed Critical Forbes Medi Tech Inc

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE398629T1 publication Critical patent/ATE398629T1/de

Links

239000000203 mixture Substances 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
239000004215 Carbon black (E152) Substances 0.000 abstract 3
229930195733 hydrocarbon Natural products 0.000 abstract 3
150000002430 hydrocarbons Chemical class 0.000 abstract 3
229940068065 phytosterols Drugs 0.000 abstract 3
LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 abstract 2
239000002184 metal Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 abstract 1
VGSSUFQMXBFFTM-UHFFFAOYSA-N (24R)-24-ethyl-5alpha-cholestane-3beta,5,6beta-triol Natural products C1C(O)C2(O)CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 VGSSUFQMXBFFTM-UHFFFAOYSA-N 0.000 abstract 1
ARYTXMNEANMLMU-UHFFFAOYSA-N 24alpha-methylcholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(C)C(C)C)C1(C)CC2 ARYTXMNEANMLMU-UHFFFAOYSA-N 0.000 abstract 1
OILXMJHPFNGGTO-NRHJOKMGSA-N Brassicasterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@](C)([C@H]([C@@H](/C=C/[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 OILXMJHPFNGGTO-NRHJOKMGSA-N 0.000 abstract 1
SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 abstract 1
BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 abstract 1
LGJMUZUPVCAVPU-JFBKYFIKSA-N Sitostanol Natural products O[C@@H]1C[C@H]2[C@@](C)([C@@H]3[C@@H]([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)CC2)CC1 LGJMUZUPVCAVPU-JFBKYFIKSA-N 0.000 abstract 1
OILXMJHPFNGGTO-ZRUUVFCLSA-N UNPD197407 Natural products C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)C=C[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZRUUVFCLSA-N 0.000 abstract 1
229940076810 beta sitosterol Drugs 0.000 abstract 1
NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 abstract 1
235000004420 brassicasterol Nutrition 0.000 abstract 1
OILXMJHPFNGGTO-ZAUYPBDWSA-N brassicasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZAUYPBDWSA-N 0.000 abstract 1
ARYTXMNEANMLMU-ATEDBJNTSA-N campestanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]2(C)CC1 ARYTXMNEANMLMU-ATEDBJNTSA-N 0.000 abstract 1
235000000431 campesterol Nutrition 0.000 abstract 1
SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 abstract 1
230000000536 complexating effect Effects 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229950005143 sitosterol Drugs 0.000 abstract 1
KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 abstract 1
NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 abstract 1
239000011877 solvent mixture Substances 0.000 abstract 1
LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1
239000002023 wood Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B13/00—Recovery of fats, fatty oils or fatty acids from waste materials
- C11B13/02—Recovery of fats, fatty oils or fatty acids from waste materials from soap stock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B13/00—Recovery of fats, fatty oils or fatty acids from waste materials
- C11B13/005—Recovery of fats, fatty oils or fatty acids from waste materials of residues of the fabrication of wood-cellulose (in particular tall-oil)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/74—Recovery of fats, fatty oils, fatty acids or other fatty substances, e.g. lanolin or waxes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Wood Science & Technology (AREA)
Hematology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Obesity (AREA)
Diabetes (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT00922365T 1999-04-27 2000-04-27 Verfahren zur herstellung einer phytosterolzusammensetzung ATE398629T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30013599A	1999-04-27	1999-04-27

Publications (1)

Publication Number	Publication Date
ATE398629T1 true ATE398629T1 (de)	2008-07-15

Family

ID=23157859

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00922365T ATE398629T1 (de)	1999-04-27	2000-04-27	Verfahren zur herstellung einer phytosterolzusammensetzung

Country Status (13)

Country	Link
EP (1)	EP1173464B1 (de)
JP (1)	JP2002543088A (de)
AT (1)	ATE398629T1 (de)
AU (1)	AU4279400A (de)
BR (1)	BR0010062A (de)
CA (1)	CA2372154A1 (de)
CY (1)	CY1110390T1 (de)
DE (1)	DE60039232D1 (de)
DK (1)	DK1173464T3 (de)
ES (1)	ES2308979T3 (de)
PT (1)	PT1173464E (de)
SI (1)	SI1173464T1 (de)
WO (1)	WO2000064921A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA02007096A (es) *	2000-01-21	2003-01-28	Forbes Medi Tech Inc	Nuevos compuestos cristalinos que comprenden fitosteroles y fitostanoles o derivados de los mismos.
JP4707862B2 (ja) *	2001-04-16	2011-06-22	花王株式会社	植物ステロールの製法
MXPA06001003A (es) *	2003-07-29	2006-04-11	Unilever Nv	Producto alimenticio que comprende fitosteroles.
EP1568760A1 (de) *	2004-02-06	2005-08-31	Härting Glade, Thomas Francis	Verfahren zur Raffination eines Rohstoffs enthalten Schwarzlauge, Rohtallöl oder Tallpech
EP2252626B1 (de)	2008-03-10	2014-07-23	SunPine AB	Rückgewinnung von phytosterolen aus restpflanzenölströmen
JP5412301B2 (ja) *	2009-02-17	2014-02-12	花王株式会社	植物油の精製・製造方法
JP5378001B2 (ja) *	2009-02-17	2013-12-25	花王株式会社	脂肪酸アルキルエステルの精製方法
US9011937B2 (en)	2010-11-22	2015-04-21	Phoenix Biotechnology, Inc.	Method of treating neurological conditions with extract of Nerium species or Thevetia species
US10307450B2 (en)	2010-01-11	2019-06-04	Phoenix Biotechnology, Inc.	Method of treating neurological conditions with extract of Nerium species or Thevetia species
US10383886B2 (en)	2010-01-11	2019-08-20	Phoenix Biotechnology, Inc.	Method of treating neurological conditions with oleandrin
US8039025B1 (en)	2010-10-15	2011-10-18	Life Plus, LLC	Methods and dosage forms for the treatment of human cancers
US10729735B1 (en)	2016-09-14	2020-08-04	Phoenix Biotechnology, Inc.	Method and compostitions for treating coronavirus infection
US10702567B2 (en)	2016-09-14	2020-07-07	Phoenix Biotechnology, Inc.	Method and compositions for treating viral infection
US10596186B2 (en)	2016-09-14	2020-03-24	Phoenix Biotechnology, Inc.	Method and compositions for treating viral infections
MX2020002884A (es)	2017-09-14	2020-10-05	Phoenix Biotechnology Inc	Método y composición neuroprotectora mejorada para tratar afecciones neurológicas.
US11629309B2 (en)	2017-09-14	2023-04-18	Fermenta Biotech Limited	Solvent free process for extraction of cholesterol from milk fat
US11331291B2 (en)	2017-09-14	2022-05-17	Phoenix Biotechnology, Inc.	Method of and improved composition for treating triterpene-responsive conditions, diseases or disorders
CA3146266A1 (en) *	2019-09-27	2021-04-01	Basf Se	Process for the purification of phytosterol
US11806359B2 (en)	2020-03-31	2023-11-07	Phoenix Biotechnology, Inc.	Method and compositions for treating Coronavirus infection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE827199C (de) *	1948-02-09	1952-01-07	Konink Veenendaalsche Sajeten	Verfahren zur Gewinnung von Sterinen
NL127423C (de) *	1967-05-11
US3840570A (en) *	1970-12-07	1974-10-08	Procter & Gamble	Process for preparing sterols from tall oil pitch
US4044031A (en) *	1976-07-02	1977-08-23	Ake Allan Johansson	Process for the separation of sterols
DE2656208A1 (de) *	1976-12-11	1978-06-15	Henkel Kgaa	Verfahren zur isolierung von sterinen aus fettverarbeitungsrueckstaenden
US4425275A (en) *	1982-07-12	1984-01-10	Eastman Kodak Company	Process for separating 3-hydroxy steroids or sterols from mixtures such as lipids
ES2464465T3 (es) *	1994-09-29	2014-06-02	Pharmachem Laboratories, Inc.	Composiciones de esteroles a partir de jabón de pulpa

2000
- 2000-04-27 DE DE60039232T patent/DE60039232D1/de not_active Expired - Lifetime
- 2000-04-27 DK DK00922365T patent/DK1173464T3/da active
- 2000-04-27 SI SI200031006T patent/SI1173464T1/sl unknown
- 2000-04-27 AU AU42794/00A patent/AU4279400A/en not_active Abandoned
- 2000-04-27 BR BR0010062A patent/BR0010062A/pt not_active Application Discontinuation
- 2000-04-27 WO PCT/CA2000/000455 patent/WO2000064921A2/en not_active Ceased
- 2000-04-27 EP EP20000922365 patent/EP1173464B1/de not_active Expired - Lifetime
- 2000-04-27 AT AT00922365T patent/ATE398629T1/de not_active IP Right Cessation
- 2000-04-27 CA CA 2372154 patent/CA2372154A1/en not_active Abandoned
- 2000-04-27 PT PT00922365T patent/PT1173464E/pt unknown
- 2000-04-27 ES ES00922365T patent/ES2308979T3/es not_active Expired - Lifetime
- 2000-04-27 JP JP2000614270A patent/JP2002543088A/ja active Pending
2008
- 2008-07-21 CY CY20081100754T patent/CY1110390T1/el unknown

Also Published As

Publication number	Publication date
BR0010062A (pt)	2002-05-21
ES2308979T3 (es)	2008-12-16
WO2000064921A2 (en)	2000-11-02
EP1173464B1 (de)	2008-06-18
JP2002543088A (ja)	2002-12-17
CY1110390T1 (el)	2012-05-23
CA2372154A1 (en)	2000-11-02
DK1173464T3 (da)	2008-10-06
WO2000064921A3 (en)	2001-07-12
SI1173464T1 (sl)	2009-02-28
EP1173464A2 (de)	2002-01-23
AU4279400A (en)	2000-11-10
PT1173464E (pt)	2008-08-05
DE60039232D1 (de)	2008-07-31

Legal Events

Date

Code

Title

Description

2008-12-15

UEP

Publication of translation of european patent specification

Ref document number: 1173464

Country of ref document: EP

2012-01-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE398629T1 (de)	2008-07-15	Verfahren zur herstellung einer phytosterolzusammensetzung
DE60009326D1 (de)	2004-04-29	Verfahren zur herstellung von silicoaluminophosphat-molekularsieben
ATE411336T1 (de)	2008-10-15	Verfahren zur behandlung von birkenrinde und die isolierung von natürlichen produkten davon
ATE302786T1 (de)	2005-09-15	Verfahren zur herstllung von clarithromycin polymorphen und polymorph iv
PE20040819A1 (es)	2004-12-25	Proceso para recuperar un metal precioso a partir de un material
DE69920017D1 (de)	2004-10-14	Neue form vom irbesartan, verfahren um diese form zu erhalten und sie enthaltende pharmazeutische zusammensetzungen
DK0783514T3 (da)	2002-08-05	Sterolsammensætninger fra pulpdannende sæbe
ATE491716T1 (de)	2011-01-15	Verfahren zur herstellung von drospirenon
DE60119711D1 (de)	2006-06-22	Verfahren zur herstellung von funktionalierten polyalkyleniminen, diese enthaltende zusammenstellungen und ihre verwendungen
HUP9900009A2 (hu)	1999-03-29	Terpénmentes és/vagy magas flavonoid glikozid tartalmú Gingkgo biloba flavonoid extraktum
DE69617419D1 (de)	2002-01-10	Pyrometallurgisches verfahren zur behandlung von wolframhaltigen materialien
NO20023276L (no)	2002-09-09	Fremgangsmåter fremstilling av betulinsyre
DE69820580D1 (de)	2004-01-29	Verfahren zur Abtrennung von Metallen durch micellare Ultrafiltration, geeignet zur Behandlung von radioaktiven Abfallstoffen
ATE159259T1 (de)	1997-11-15	Verfahren zur herstellung taurin-konjugierter gallensäure
ATE14317T1 (de)	1985-08-15	Verfahren zur herstellung von zwischenprodukten in der synthese von vitamin d3-metaboliten und neue zwischenprodukte.
Purohit et al.	1991	A betulinic acid glycoside from Schefflera venulosa
Dodson et al.	1959	Microbiological transformations. IV. The oxidation of dehydroisoandrosterone at C-7
Balssa et al.	2014	An easy stereoselective synthesis of 5 (10)-estrene-3β, 17α-diol, a biological marker of pregnancy in the mare
Kirk et al.	1983	Synthesis of [26, 27-2 H 6] cholesterol and derivatives substituted in the side chain
ATE232542T1 (de)	2003-02-15	Neue 19-nor 11-beta-substituierte steroide, ein verfahren zu ihrer herstellung sowie zwischenprodukten dieses verfahrens und ihre anwendung als medikamenten
DK1150968T3 (da)	2004-05-10	Fremgangsmåde til fremstilling af phytosteriner
CN103720720A (zh)	2014-04-16	天然孕马结合雌激素纯化精制方法及其所用非离子非极性精细分离树脂的应用
DE60014096D1 (de)	2004-10-28	Durch 11-beta-aryl-17,17-spirothiolan substituierte steroide
US4279828A (en)	1981-07-21	Process for separating 3-hydroxy steroids or sterols from mixtures such as lipids
SE540791C2 (en)	2018-11-13	Extraction of phytosterols