ATE399165T1 - Chinolinverbindungen und deren verwendungen - Google Patents

Chinolinverbindungen und deren verwendungen

Info

Publication number
ATE399165T1
ATE399165T1 AT04782827T AT04782827T ATE399165T1 AT E399165 T1 ATE399165 T1 AT E399165T1 AT 04782827 T AT04782827 T AT 04782827T AT 04782827 T AT04782827 T AT 04782827T AT E399165 T1 ATE399165 T1 AT E399165T1
Authority
AT
Austria
Prior art keywords
compounds
release
quinoline compounds
methods
receptor signaling
Prior art date
Application number
AT04782827T
Other languages
English (en)
Inventor
Singh Rajinder
Lin Hui
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE399165T1 publication Critical patent/ATE399165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT04782827T 2003-09-12 2004-09-01 Chinolinverbindungen und deren verwendungen ATE399165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50260503P 2003-09-12 2003-09-12

Publications (1)

Publication Number Publication Date
ATE399165T1 true ATE399165T1 (de) 2008-07-15

Family

ID=34421502

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04782827T ATE399165T1 (de) 2003-09-12 2004-09-01 Chinolinverbindungen und deren verwendungen

Country Status (6)

Country Link
US (1) US8008501B2 (de)
EP (1) EP1675850B1 (de)
AT (1) ATE399165T1 (de)
DE (1) DE602004014629D1 (de)
ES (1) ES2308251T3 (de)
WO (1) WO2005033103A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113519A1 (en) 2004-05-14 2005-12-01 Irm Llc Compounds and compositions as ppar modulators
CA2834062A1 (en) 2011-05-10 2012-11-15 Merck Sharp & Dohme Corp. Pyridyl aminopyridines as syk inhibitors
EP2706853B1 (de) 2011-05-10 2017-06-14 Merck Sharp & Dohme Corp. Aminopyrimidine als syk-hemmer
US9145391B2 (en) 2011-05-10 2015-09-29 Merck Sharp & Dohme Corp. Bipyridylaminopyridines as Syk inhibitors
US9216173B2 (en) 2011-10-05 2015-12-22 Merck Sharp & Dohme Corp. 2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
EP2763975B1 (de) 2011-10-05 2016-04-06 Merck Sharp & Dohme Corp. 3-pyridyl-carboxamidhaltige milztyrosinkinase-(syk)-hemmer
WO2013052391A1 (en) 2011-10-05 2013-04-11 Merck Sharp & Dohme Corp. PHENYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS
EP2863914B1 (de) 2012-06-20 2018-10-03 Merck Sharp & Dohme Corp. Pyrazolylderivate als syk-hemmer
EP2863913B1 (de) 2012-06-20 2018-09-12 Merck Sharp & Dohme Corp. Imidazolylanaloga als syk-hemmer
EP2863915B1 (de) 2012-06-22 2017-12-06 Merck Sharp & Dohme Corp. Substituierte diazin- und triazin-milz-tyrosinkinase-hemmer
EP2863916B1 (de) 2012-06-22 2018-07-18 Merck Sharp & Dohme Corp. Substituierte pyridin-milz-tyrosinkinaseinhibitoren
US9353066B2 (en) 2012-08-20 2016-05-31 Merck Sharp & Dohme Corp. Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors
WO2014048065A1 (en) 2012-09-28 2014-04-03 Merck Sharp & Dohme Corp. Triazolyl derivatives as syk inhibitors
EP2931281B1 (de) 2012-12-12 2018-01-17 Merck Sharp & Dohme Corp. Aminopyridinhaltige milz-tyrosinkinase-hemmer
EP2934525B1 (de) 2012-12-21 2019-05-08 Merck Sharp & Dohme Corp. Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer
WO2014176210A1 (en) 2013-04-26 2014-10-30 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
EP2988749B1 (de) 2013-04-26 2019-08-14 Merck Sharp & Dohme Corp. Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer
WO2015094997A1 (en) 2013-12-20 2015-06-25 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
WO2015095444A1 (en) 2013-12-20 2015-06-25 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
US9822107B2 (en) 2013-12-20 2017-11-21 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
WO2015138273A1 (en) 2014-03-13 2015-09-17 Merck Sharp & Dohme Corp. 2-pyrazine carboxamides as spleen tyrosine kinase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES448386A1 (es) * 1975-06-05 1978-04-16 Hoechst Ag Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico.
DE3225169A1 (de) 1982-07-06 1984-01-12 Basf Ag, 6700 Ludwigshafen Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von pilzen
DE3621540A1 (de) * 1986-06-27 1988-01-07 Basf Ag Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von bakterien und pilzen
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
JP4245682B2 (ja) * 1997-12-25 2009-03-25 協和発酵キリン株式会社 キノリン誘導体、イソキノリン誘導体、およびシンノリン誘導体、並びに抗炎症剤および抗アレルギー剤

Also Published As

Publication number Publication date
US8008501B2 (en) 2011-08-30
WO2005033103A1 (en) 2005-04-14
EP1675850B1 (de) 2008-06-25
US20050113412A1 (en) 2005-05-26
DE602004014629D1 (de) 2008-08-07
EP1675850A1 (de) 2006-07-05
ES2308251T3 (es) 2008-12-01

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