ATE399165T1 - Chinolinverbindungen und deren verwendungen - Google Patents

Chinolinverbindungen und deren verwendungen

Info

Publication number
ATE399165T1
ATE399165T1 AT04782827T AT04782827T ATE399165T1 AT E399165 T1 ATE399165 T1 AT E399165T1 AT 04782827 T AT04782827 T AT 04782827T AT 04782827 T AT04782827 T AT 04782827T AT E399165 T1 ATE399165 T1 AT E399165T1
Authority
AT
Austria
Prior art keywords
compounds
release
quinoline compounds
methods
receptor signaling
Prior art date
Application number
AT04782827T
Other languages
English (en)
Inventor
Singh Rajinder
Lin Hui
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE399165T1 publication Critical patent/ATE399165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT04782827T 2003-09-12 2004-09-01 Chinolinverbindungen und deren verwendungen ATE399165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50260503P 2003-09-12 2003-09-12

Publications (1)

Publication Number Publication Date
ATE399165T1 true ATE399165T1 (de) 2008-07-15

Family

ID=34421502

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04782827T ATE399165T1 (de) 2003-09-12 2004-09-01 Chinolinverbindungen und deren verwendungen

Country Status (6)

Country Link
US (1) US8008501B2 (de)
EP (1) EP1675850B1 (de)
AT (1) ATE399165T1 (de)
DE (1) DE602004014629D1 (de)
ES (1) ES2308251T3 (de)
WO (1) WO2005033103A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070034993A (ko) * 2004-05-14 2007-03-29 아이알엠 엘엘씨 Ｐｐａｒ 조절제로서의 화합물 및 조성물
EP2706853B1 (de) 2011-05-10 2017-06-14 Merck Sharp & Dohme Corp. Aminopyrimidine als syk-hemmer
JP2014513687A (ja) 2011-05-10 2014-06-05 メルク・シャープ・アンド・ドーム・コーポレーション Ｓｙｋ阻害薬としてのピリジルアミノピリジン
WO2012154518A1 (en) 2011-05-10 2012-11-15 Merck Sharp & Dohme Corp. Bipyridylaminopyridines as syk inhibitors
US8987456B2 (en) 2011-10-05 2015-03-24 Merck Sharp & Dohme Corp. 3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
WO2013052391A1 (en) 2011-10-05 2013-04-11 Merck Sharp & Dohme Corp. PHENYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS
EP2763976B1 (de) 2011-10-05 2016-05-18 Merck Sharp & Dohme Corp. 2-pyridyl-carboxamid-haltige milztyrosinkinase-hemmer
US9242984B2 (en) 2012-06-20 2016-01-26 Merck Sharp & Dohme Corp. Pyrazolyl derivatives as Syk inhibitors
WO2013192128A1 (en) 2012-06-20 2013-12-27 Merck Sharp & Dohme Corp. Imidazolyl analogs as syk inhibitors
WO2013192088A1 (en) 2012-06-22 2013-12-27 Merck Sharp & Dohme Corp. SUBSTITUTED DIAZINE AND TRIAZINE SPLEEN TYROSINE KINASE (Syk) INHIBITORS
EP2863916B1 (de) 2012-06-22 2018-07-18 Merck Sharp & Dohme Corp. Substituierte pyridin-milz-tyrosinkinaseinhibitoren
WO2014031438A2 (en) 2012-08-20 2014-02-27 Merck Sharp & Dohme Corp. SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS
EP2900665B1 (de) 2012-09-28 2018-01-03 Merck Sharp & Dohme Corp. Triazolylderivate als syk-hemmer
US9624210B2 (en) 2012-12-12 2017-04-18 Merck Sharp & Dohme Corp. Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors
EP2934525B1 (de) 2012-12-21 2019-05-08 Merck Sharp & Dohme Corp. Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer
EP2988744A4 (de) 2013-04-26 2016-11-02 Merck Sharp & Dohme Thiazolsubstituierte aminoheteroaryle als milztyrosinkinasehemmer
EP2988749B1 (de) 2013-04-26 2019-08-14 Merck Sharp & Dohme Corp. Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer
US9670196B2 (en) 2013-12-20 2017-06-06 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors
WO2015094997A1 (en) 2013-12-20 2015-06-25 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
EP3083559B1 (de) 2013-12-20 2021-03-10 Merck Sharp & Dohme Corp. Thiazolsubstituierte aminoheteroaryle als milztyrosinkinasehemmer
EP3116506B1 (de) 2014-03-13 2019-04-17 Merck Sharp & Dohme Corp. 2-pyrazincarboxamide als milz-tyrosinkinase-inhibitoren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178596C (nl) * 1975-06-05 1986-04-16 Hoechst Ag Werkwijze voor het bereiden van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor het bereiden van daarin als geneeskrachtige verbindingen te gebruiken 5-methylisoxazool-4-carbonzuuraniliden.
DE3225169A1 (de) 1982-07-06 1984-01-12 Basf Ag, 6700 Ludwigshafen Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von pilzen
DE3621540A1 (de) * 1986-06-27 1988-01-07 Basf Ag Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von bakterien und pilzen
WO1994024095A1 (en) 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
JP4245682B2 (ja) 1997-12-25 2009-03-25 協和発酵キリン株式会社 キノリン誘導体、イソキノリン誘導体、およびシンノリン誘導体、並びに抗炎症剤および抗アレルギー剤

Also Published As

Publication number Publication date
WO2005033103A1 (en) 2005-04-14
US20050113412A1 (en) 2005-05-26
ES2308251T3 (es) 2008-12-01
DE602004014629D1 (de) 2008-08-07
EP1675850B1 (de) 2008-06-25
US8008501B2 (en) 2011-08-30
EP1675850A1 (de) 2006-07-05

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