ATE399774T1 - N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen - Google Patents

N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen

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Publication number
ATE399774T1
ATE399774T1 AT99943025T AT99943025T ATE399774T1 AT E399774 T1 ATE399774 T1 AT E399774T1 AT 99943025 T AT99943025 T AT 99943025T AT 99943025 T AT99943025 T AT 99943025T AT E399774 T1 ATE399774 T1 AT E399774T1
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AT
Austria
Prior art keywords
iminomethyl
medications
production
pharmaceutical preparations
preparations containing
Prior art date
Application number
AT99943025T
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English (en)
Inventor
Dennis Bigg
De Lassauniere Pierre Chabrier
Serge Auvin
Jeremiah Harnett
Gerard Ulibarri
Original Assignee
Sod Conseils Rech Applic
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Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
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Publication of ATE399774T1 publication Critical patent/ATE399774T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P39/06—Free radical scavengers or antioxidants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
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  • Biochemistry (AREA)
AT99943025T 1998-09-23 1999-09-22 N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen ATE399774T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9811867A FR2784678B1 (fr) 1998-09-23 1998-09-23 Nouveaux derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ATE399774T1 true ATE399774T1 (de) 2008-07-15

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ID=9530743

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AT99943025T ATE399774T1 (de) 1998-09-23 1999-09-22 N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen

Country Status (26)

Country Link
US (5) US6482822B1 (de)
EP (1) EP1115720B1 (de)
JP (1) JP2003517444A (de)
KR (1) KR100655340B1 (de)
CN (1) CN1144799C (de)
AR (1) AR024837A1 (de)
AT (1) ATE399774T1 (de)
AU (1) AU759958B2 (de)
BR (1) BR9913899A (de)
CA (1) CA2344223A1 (de)
CZ (1) CZ299664B6 (de)
DE (1) DE69939021D1 (de)
DK (1) DK1115720T3 (de)
ES (1) ES2310045T3 (de)
FR (1) FR2784678B1 (de)
HK (1) HK1043365B (de)
HU (1) HUP0104013A3 (de)
IL (2) IL141997A0 (de)
MY (1) MY123219A (de)
NO (1) NO328466B1 (de)
NZ (1) NZ511188A (de)
PL (1) PL347471A1 (de)
PT (1) PT1115720E (de)
RU (1) RU2230742C2 (de)
WO (1) WO2000017191A2 (de)
ZA (1) ZA200103206B (de)

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RU2428983C2 (ru) * 2005-09-02 2011-09-20 Санесис Фармасьютикалз, Инк. Способы применения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
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CA3012229C (en) 2008-07-08 2020-11-10 Incyte Holdings Corporation 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
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CN104119295B (zh) * 2013-04-27 2018-04-10 天津药物研究院 吩噻嗪类一氧化氮供体、其制备方法和用途
EP3744715A1 (de) 2013-11-08 2020-12-02 Incyte Holdings Corporation Verfahren zur synthese eines indolamin-2,3-dioxygenaseinhibitors
CN107110874B (zh) 2014-09-26 2019-06-04 雅培医护站股份有限公司 用于测定流体样品中的凝固的传感器
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FR2784678A1 (fr) 2000-04-21
IL141997A0 (en) 2002-03-10
CN1335841A (zh) 2002-02-13
IL141997A (en) 2008-07-08
US7186752B2 (en) 2007-03-06
RU2230742C2 (ru) 2004-06-20
HK1043365A1 (en) 2002-09-13
WO2000017191A2 (fr) 2000-03-30
CZ20011056A3 (cs) 2002-01-16
FR2784678B1 (fr) 2002-11-29
US6809090B2 (en) 2004-10-26
NZ511188A (en) 2003-08-29
ZA200103206B (en) 2002-07-19
CZ299664B6 (cs) 2008-10-08
PT1115720E (pt) 2008-10-08
EP1115720A2 (de) 2001-07-18
MY123219A (en) 2006-05-31
US20040097494A1 (en) 2004-05-20
NO20011478L (no) 2001-03-22
US6620840B1 (en) 2003-09-16
DE69939021D1 (de) 2008-08-14
US20050197329A1 (en) 2005-09-08
NO20011478D0 (no) 2001-03-22
DK1115720T3 (da) 2008-11-03
CA2344223A1 (fr) 2000-03-30
AU5631599A (en) 2000-04-10
AR024837A1 (es) 2002-10-30
HUP0104013A2 (hu) 2002-04-29
HK1043365B (zh) 2005-01-07
US6482822B1 (en) 2002-11-19
BR9913899A (pt) 2001-07-03
NO328466B1 (no) 2010-02-22
JP2003517444A (ja) 2003-05-27
KR100655340B1 (ko) 2006-12-08
EP1115720B1 (de) 2008-07-02
AU759958B2 (en) 2003-05-01
ES2310045T3 (es) 2008-12-16
KR20010085832A (ko) 2001-09-07
CN1144799C (zh) 2004-04-07
US20050027009A1 (en) 2005-02-03
HUP0104013A3 (en) 2003-01-28
PL347471A1 (en) 2002-04-08

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