ATE399866T1 - Apoptosis induzierendes protein und dieses kodierendes gen - Google Patents
Apoptosis induzierendes protein und dieses kodierendes genInfo
- Publication number
- ATE399866T1 ATE399866T1 AT97917435T AT97917435T ATE399866T1 AT E399866 T1 ATE399866 T1 AT E399866T1 AT 97917435 T AT97917435 T AT 97917435T AT 97917435 T AT97917435 T AT 97917435T AT E399866 T1 ATE399866 T1 AT E399866T1
- Authority
- AT
- Austria
- Prior art keywords
- apoptosis
- gene encoding
- inducing protein
- kinase activity
- protein
- Prior art date
Links
- 102000010565 Apoptosis Regulatory Proteins Human genes 0.000 title abstract 2
- 108010063104 Apoptosis Regulatory Proteins Proteins 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 3
- 102100023275 Dual specificity mitogen-activated protein kinase kinase 3 Human genes 0.000 abstract 1
- 102100023274 Dual specificity mitogen-activated protein kinase kinase 4 Human genes 0.000 abstract 1
- 101710146518 Dual specificity mitogen-activated protein kinase kinase 4 Proteins 0.000 abstract 1
- 101001115394 Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Proteins 0.000 abstract 1
- 101001018196 Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Proteins 0.000 abstract 1
- 102100033127 Mitogen-activated protein kinase kinase kinase 5 Human genes 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12232096 | 1996-04-19 | ||
| JP24106396A JP3839103B2 (ja) | 1996-04-19 | 1996-08-23 | アポトーシス誘導タンパク質およびそれをコードする遺伝子 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE399866T1 true ATE399866T1 (de) | 2008-07-15 |
Family
ID=26459470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97917435T ATE399866T1 (de) | 1996-04-19 | 1997-04-18 | Apoptosis induzierendes protein und dieses kodierendes gen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6194187B1 (de) |
| EP (1) | EP0896055B1 (de) |
| JP (1) | JP3839103B2 (de) |
| AT (1) | ATE399866T1 (de) |
| AU (1) | AU2576397A (de) |
| DE (1) | DE69738803D1 (de) |
| WO (1) | WO1997040143A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999040912A1 (en) * | 1998-02-11 | 1999-08-19 | The Brigham And Women's Hospital, Inc. | Method of stimulating apoptosis using trichothecene mycotoxins |
| US6080546A (en) * | 1999-07-23 | 2000-06-27 | Isis Pharmaceuticals Inc. | Antisense modulation of MEKK5 expression |
| US20030224378A1 (en) * | 2001-04-10 | 2003-12-04 | Plowman Gregory D. | Novel human protein kinases and protein kinase-like enzymes |
| WO2002038179A1 (en) * | 2000-11-10 | 2002-05-16 | Kissei Pharmaceutical Co., Ltd. | Preventives or remedies for endoplasmic reticulum stress-associated diseases |
| WO2003063905A1 (en) * | 2002-01-31 | 2003-08-07 | Center For Advanced Science And Technology Incubation, Ltd. | Preventives or remedies for immunological diseases |
| AU2003294668A1 (en) * | 2002-09-06 | 2004-04-08 | Institut Curie | Use of inhibitors of compounds involved in the jun kinase (jnk) biochemical cellular pathway for the treatment or diagnosis of liposarcomas |
| WO2004048565A1 (ja) | 2002-11-22 | 2004-06-10 | Takeda Pharmaceutical Company Limited | アポトーシス関連蛋白質およびその用途 |
| JP4488720B2 (ja) * | 2002-11-22 | 2010-06-23 | 武田薬品工業株式会社 | アポトーシス関連蛋白質およびその用途 |
| WO2005009470A1 (ja) * | 2003-07-28 | 2005-02-03 | Osaka Industrial Promotion Organization | Ask1阻害剤を有効成分とする心不全治療薬およびそのスクリーニング方法 |
| JP4659736B2 (ja) * | 2004-04-27 | 2011-03-30 | 武田薬品工業株式会社 | スクリーニング方法 |
| WO2005114199A1 (en) * | 2004-05-13 | 2005-12-01 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 5 (map3k5) |
| WO2009030094A1 (fr) * | 2007-09-06 | 2009-03-12 | Zhejiang University | Fonction et utilisation d'une nouvelle protéine induisant une apoptose associée aux lysosomes contenant les domaines ph et fyve (lapf) |
| WO2011041293A1 (en) | 2009-09-30 | 2011-04-07 | Takeda Pharmaceutical Company Limited | Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors |
| SI2531501T1 (sl) | 2010-02-03 | 2014-04-30 | Takeda Pharmaceutical Company Limited | Inhibitorji kinaze-1, ki regulirajo signal apoptoze |
| US10654833B2 (en) | 2018-06-28 | 2020-05-19 | Hepatikos Therapeutics, Llc | ASK1 isoindolin-1-one inhibitors and methods of use thereof |
-
1996
- 1996-08-23 JP JP24106396A patent/JP3839103B2/ja not_active Expired - Fee Related
-
1997
- 1997-04-18 WO PCT/JP1997/001348 patent/WO1997040143A1/ja not_active Ceased
- 1997-04-18 AU AU25763/97A patent/AU2576397A/en not_active Abandoned
- 1997-04-18 AT AT97917435T patent/ATE399866T1/de not_active IP Right Cessation
- 1997-04-18 US US09/171,410 patent/US6194187B1/en not_active Expired - Lifetime
- 1997-04-18 EP EP97917435A patent/EP0896055B1/de not_active Expired - Lifetime
- 1997-04-18 DE DE69738803T patent/DE69738803D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3839103B2 (ja) | 2006-11-01 |
| US6194187B1 (en) | 2001-02-27 |
| WO1997040143A1 (en) | 1997-10-30 |
| DE69738803D1 (de) | 2008-08-14 |
| EP0896055A2 (de) | 1999-02-10 |
| EP0896055B1 (de) | 2008-07-02 |
| EP0896055A4 (de) | 2004-05-12 |
| JPH1093A (ja) | 1998-01-06 |
| AU2576397A (en) | 1997-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |