ATE400287T1 - Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit - Google Patents

Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit

Info

Publication number
ATE400287T1
ATE400287T1 AT02735312T AT02735312T ATE400287T1 AT E400287 T1 ATE400287 T1 AT E400287T1 AT 02735312 T AT02735312 T AT 02735312T AT 02735312 T AT02735312 T AT 02735312T AT E400287 T1 ATE400287 T1 AT E400287T1
Authority
AT
Austria
Prior art keywords
disease
treatment
neurodegenerative diseases
low dose
lhrh antagonists
Prior art date
Application number
AT02735312T
Other languages
English (en)
Inventor
Juergen Engel
Rainer Voegeli
Original Assignee
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh
Application granted granted Critical
Publication of ATE400287T1 publication Critical patent/ATE400287T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT02735312T 2001-04-30 2002-04-27 Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit ATE400287T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28743401P 2001-04-30 2001-04-30

Publications (1)

Publication Number Publication Date
ATE400287T1 true ATE400287T1 (de) 2008-07-15

Family

ID=23102886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735312T ATE400287T1 (de) 2001-04-30 2002-04-27 Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit

Country Status (27)

Country Link
US (1) US7288517B2 (de)
EP (1) EP1392348B1 (de)
JP (1) JP2004529207A (de)
KR (1) KR20040000446A (de)
CN (1) CN1317030C (de)
AT (1) ATE400287T1 (de)
AU (1) AU2002310788B2 (de)
BG (1) BG108339A (de)
BR (1) BR0209290A (de)
CA (1) CA2444876A1 (de)
CZ (1) CZ20033167A3 (de)
DE (1) DE60227507D1 (de)
DK (1) DK1392348T3 (de)
ES (1) ES2307760T3 (de)
HU (1) HUP0400067A2 (de)
IL (1) IL156777A0 (de)
MX (1) MXPA03008666A (de)
NO (1) NO20034322D0 (de)
NZ (1) NZ544417A (de)
PL (1) PL362319A1 (de)
PT (1) PT1392348E (de)
RU (1) RU2319501C2 (de)
SI (1) SI1392348T1 (de)
SK (1) SK14512003A3 (de)
UA (1) UA80679C2 (de)
WO (1) WO2002102401A1 (de)
ZA (1) ZA200305326B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US20020077327A1 (en) * 1999-09-23 2002-06-20 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
AU7102201A (en) * 2000-07-05 2002-01-14 Yamanouchi Pharma Co Ltd Propane-1,3-dione derivatives
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
EP1752452A4 (de) * 2004-06-04 2010-07-14 Astellas Pharma Inc Propan-1,3-dionderivat und dessen salz
US20080171736A1 (en) * 2004-12-23 2008-07-17 Gregory Christopher W Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists
WO2006071274A2 (en) * 2004-12-23 2006-07-06 Voyager Pharmaceutical Corporation Leuprolide acetate and acetylcholinesterase inhibitors or nmda receptor antagonists for the treatment of alzheimer’s disease
RU2404973C2 (ru) * 2005-03-31 2010-11-27 Астеллас Фарма Инк. Производное соединение пропан-1,3-диона или его соль
US8642598B2 (en) * 2006-10-21 2014-02-04 Abbvie Inc. Heterocyclic compounds and their use as glycogen synthase kinase 3 inhibitors
WO2009039983A2 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
WO2009043441A1 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag D-ala-gln-octadecyl ester as a therapeutic agent
EP2095818A1 (de) * 2008-02-29 2009-09-02 AEterna Zentaris GmbH Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen
EP2307040B1 (de) * 2008-05-29 2015-09-09 Isr Immune System Regulation Ab Gnrh und sexhormone zur behandlung von viruserkrankungen, insbesondere hiv/aids
CN103119035B (zh) 2010-09-27 2015-09-30 雅培股份有限两合公司 杂环化合物和它们作为糖原合成酶激酶-3抑制剂的用途
US9090592B2 (en) 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
EP3560555A1 (de) * 2018-04-26 2019-10-30 LifeArc Zusammensetzung zur behandlung einer oder mehrerer östrogenvermittelter krankheiten
WO2025155903A1 (en) * 2024-01-19 2025-07-24 Temple University-Of The Commonwealth System Of Higher Education Compositions of antioxidant translation modulators for treating neurodegenerative disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135743A (en) 1960-06-29 1964-06-02 Sterling Drug Inc Steroido[2. 3-d]isoxazoles and preparation thereof
JP2000511532A (ja) 1996-05-20 2000-09-05 メルク エンド カンパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモンのアンタゴニスト
DE19911771B4 (de) 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
WO2000069859A1 (en) 1999-05-14 2000-11-23 Neurocrine Biosciences, Inc. Imidazo- and pyrrolo[1,2-a]pyrimid-4-ones as gonadotropin-releasing hormone receptor antagonists
CA2309395A1 (en) 1999-06-04 2000-12-04 Richard Lloyd Bowen Methods for preventing and treating alzheimer's disease
ES2249302T3 (es) * 1999-10-15 2006-04-01 Neurocrine Biosciences, Inc. Antagonistas del receptor de la hormona liberadora de gonadotropina y sus metodos de uso relacionados.
WO2001078780A1 (en) 2000-04-13 2001-10-25 Takeda Chemical Industries, Ltd. Preventives/remedies for alzheimer's disease
AU7102201A (en) 2000-07-05 2002-01-14 Yamanouchi Pharma Co Ltd Propane-1,3-dione derivatives

Also Published As

Publication number Publication date
EP1392348B1 (de) 2008-07-09
KR20040000446A (ko) 2004-01-03
CN1317030C (zh) 2007-05-23
CA2444876A1 (en) 2002-12-27
IL156777A0 (en) 2004-02-08
JP2004529207A (ja) 2004-09-24
EP1392348A1 (de) 2004-03-03
NO20034322L (no) 2003-09-26
ZA200305326B (en) 2003-07-30
HK1072000A1 (en) 2005-08-12
MXPA03008666A (es) 2004-10-15
ES2307760T3 (es) 2008-12-01
RU2319501C2 (ru) 2008-03-20
CN1575185A (zh) 2005-02-02
WO2002102401A1 (en) 2002-12-27
NO20034322D0 (no) 2003-09-26
CZ20033167A3 (cs) 2004-08-18
DE60227507D1 (de) 2008-08-21
RU2003134949A (ru) 2005-02-10
US7288517B2 (en) 2007-10-30
US20020177556A1 (en) 2002-11-28
SK14512003A3 (sk) 2004-08-03
AU2002310788B2 (en) 2007-04-05
UA80679C2 (en) 2007-10-25
PL362319A1 (en) 2004-10-18
NZ544417A (en) 2008-03-28
SI1392348T1 (sl) 2008-12-31
DK1392348T3 (da) 2008-09-29
HUP0400067A2 (hu) 2004-04-28
BR0209290A (pt) 2004-07-13
BG108339A (bg) 2004-11-30
PT1392348E (pt) 2008-09-09

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