ATE401338T1 - Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendung - Google Patents
Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendungInfo
- Publication number
- ATE401338T1 ATE401338T1 AT05815291T AT05815291T ATE401338T1 AT E401338 T1 ATE401338 T1 AT E401338T1 AT 05815291 T AT05815291 T AT 05815291T AT 05815291 T AT05815291 T AT 05815291T AT E401338 T1 ATE401338 T1 AT E401338T1
- Authority
- AT
- Austria
- Prior art keywords
- fibrin
- rheumatoid arthritis
- peptides derived
- recognized
- citrulline
- Prior art date
Links
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 title abstract 3
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002173 citrulline Drugs 0.000 title abstract 3
- 235000013477 citrulline Nutrition 0.000 title abstract 3
- 102000009123 Fibrin Human genes 0.000 title abstract 2
- 108010073385 Fibrin Proteins 0.000 title abstract 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title abstract 2
- 229950003499 fibrin Drugs 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 206010039073 rheumatoid arthritis Diseases 0.000 title abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0411782A FR2877345B1 (fr) | 2004-11-04 | 2004-11-04 | Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations |
| FR0413711A FR2879604B1 (fr) | 2004-12-22 | 2004-12-22 | Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations |
| FR0508422 | 2005-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401338T1 true ATE401338T1 (de) | 2008-08-15 |
Family
ID=35677372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05815291T ATE401338T1 (de) | 2004-11-04 | 2005-11-03 | Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8207299B2 (de) |
| EP (1) | EP1814901B1 (de) |
| JP (1) | JP5060300B2 (de) |
| AT (1) | ATE401338T1 (de) |
| DE (1) | DE602005008277D1 (de) |
| ES (1) | ES2310853T3 (de) |
| WO (1) | WO2006048556A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8683158B2 (en) | 2005-12-30 | 2014-03-25 | Intel Corporation | Steering system management code region accesses |
| FR2900657B1 (fr) * | 2006-05-03 | 2009-04-17 | Univ Toulouse | Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide |
| US20100047256A1 (en) | 2007-01-25 | 2010-02-25 | Imperial Innovations Limited | Methods |
| ES2307421B1 (es) * | 2007-04-30 | 2009-09-28 | Consejo Superiorde Investigaciones Cientificas (Csic) | Polipeptido quimerico fibrina-filagrina citruinado capaz de detectar los anticuerpos generados en la artritis reumatoide. |
| CA2707870C (en) * | 2007-12-03 | 2015-01-27 | Sqi Diagnostics Systems Inc. | Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies |
| FR2908134B1 (fr) * | 2007-12-04 | 2012-10-12 | Univ Toulouse 3 Paul Sabatier | Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide |
| EP2325195A1 (de) | 2009-11-23 | 2011-05-25 | Toscana Biomarkers S.r.l. | Virale citrullinierte Peptide und Verwendungen dafür |
| EP2402368A1 (de) | 2010-07-02 | 2012-01-04 | Toscana Biomarkers S.r.l. | Histoncitrullinierte Peptide und deren Verwendungen |
| EP2527841A1 (de) | 2011-05-25 | 2012-11-28 | Toscana Biomarkers S.r.l. | Verfahren zur Diagnose rheumatoider Arthritis |
| US10424553B2 (en) * | 2016-10-31 | 2019-09-24 | Micron Technology, Inc. | Semiconductor devices with underfill control features, and associated systems and methods |
| FR3108515B1 (fr) * | 2020-03-26 | 2022-03-25 | Ct Hospitalier Universitaire Toulouse | Colonne d’aphérèse pour le traitement de la polyarthrite rhumatoïde |
| GB202103164D0 (en) * | 2021-03-08 | 2021-04-21 | Adiga Life Sciences Inc | Therapy |
| FR3120865B1 (fr) * | 2021-03-19 | 2025-02-28 | Univ Toulouse 3 Paul Sabatier | Molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations |
| FR3120866B1 (fr) * | 2021-03-19 | 2025-02-28 | Univ Toulouse 3 Paul Sabatier | Molécule hybride comprenant un peptide citrulliné dérivé de la fibrine et un anticorps ou fragment d’anticorps se liant à CD38 et/ou CD138, et ses utilisations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2795735B1 (fr) * | 1999-07-01 | 2001-09-07 | Univ Toulouse | Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide |
| NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
-
2005
- 2005-11-03 AT AT05815291T patent/ATE401338T1/de not_active IP Right Cessation
- 2005-11-03 WO PCT/FR2005/002736 patent/WO2006048556A1/fr not_active Ceased
- 2005-11-03 US US11/577,674 patent/US8207299B2/en active Active
- 2005-11-03 EP EP05815291A patent/EP1814901B1/de not_active Expired - Lifetime
- 2005-11-03 JP JP2007538475A patent/JP5060300B2/ja not_active Expired - Lifetime
- 2005-11-03 DE DE602005008277T patent/DE602005008277D1/de not_active Expired - Lifetime
- 2005-11-03 ES ES05815291T patent/ES2310853T3/es not_active Expired - Lifetime
-
2012
- 2012-06-05 US US13/489,072 patent/US9249208B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005008277D1 (de) | 2008-08-28 |
| US9249208B2 (en) | 2016-02-02 |
| WO2006048556A1 (fr) | 2006-05-11 |
| US20130028922A1 (en) | 2013-01-31 |
| EP1814901B1 (de) | 2008-07-16 |
| ES2310853T3 (es) | 2009-01-16 |
| JP2008518898A (ja) | 2008-06-05 |
| JP5060300B2 (ja) | 2012-10-31 |
| US20090028885A1 (en) | 2009-01-29 |
| US8207299B2 (en) | 2012-06-26 |
| EP1814901A1 (de) | 2007-08-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE401338T1 (de) | Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendung | |
| MX2007010349A (es) | Composiciones y metodos para clasificar muestras biologicas. | |
| WO2003093494A3 (en) | Apparatus including ion transport detecting structures and methods of use | |
| DK1668368T3 (da) | Detektion af histon-modifikation i cellefrie nukleosomer | |
| ATE541054T1 (de) | Bio-barcode erkennung für zielmoleküle | |
| DE602006018477D1 (de) | Dna und antikörpern sowie verwendungen davon | |
| DE602006017365D1 (de) | Zusammensetzungen für die identifizierung von adenoviren | |
| MX2021011543A (es) | Sistemas de fluidos de punto de cuidado y usos de los mismos. | |
| NO20072721L (no) | Polypeptides that bind BR3 and uses thereof | |
| WO2002077259A3 (en) | Biochips including ion transport detecting structures and methods of use | |
| ATE431854T1 (de) | Auf bio-barcodes beruhender nachweis von zielanalyten | |
| ATE463512T1 (de) | Identifizierung und charakterisierung von funktionsblockierenden anti-ed-b-fibronektin antikörpern | |
| MX2009010751A (es) | Composiciones y metodos de deteccion. | |
| WO2005114218A3 (en) | Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule | |
| WO2009058331A3 (en) | Biomarkers for the detection of early stage ovarian cancer | |
| UA94945C2 (ru) | Способ выделения и определения вирусной нагрузки в образце панкреатина | |
| DE602007006634D1 (de) | Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten | |
| EA200702193A1 (ru) | Гликозилирование белков | |
| ATE416262T1 (de) | Einen grössenausschlussschritt verwendendes verbessertes bisulfit-verfahren | |
| DK1864131T3 (da) | Naturlig ligand af G protein koblet receptor RCC356 og anvendelser deraf | |
| WO2006076687A3 (en) | Elisa assays using prion-specific peptide reagents | |
| ATE333521T1 (de) | Detektion von vancomycin-resistenten enterococcus-subspezies | |
| MX2008000282A (es) | Anticuerpos monoclonales, lineas celulares de hibridomas, metodos y kits para la deteccion de fitasa. | |
| MX2010004821A (es) | Metodo para agrupar muestras para realizar un ensayo biologico. | |
| DE602006018424D1 (de) | Peptide zum nachweis von ehrlichia ewingii antikörper |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |