ATE40140T1 - Aromatase inhibierende steroide. - Google Patents

Aromatase inhibierende steroide.

Info

Publication number: ATE40140T1
Authority: AT; Austria
Prior art keywords: group; alkyl; unsubstituted; chem; substituted
Prior art date: 1985-08-01

Application number

AT86305647T

Other languages

English (en)

Inventor

Franco Faustini

Alessio Roberto D

Vittoria Villa

Salle Enrico Di

Paolo Lombardi

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-01

Filing date

1986-07-23

Publication date

1989-02-15

1986-07-23 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1989-02-15 Application granted granted Critical

1989-02-15 Publication of ATE40140T1 publication Critical patent/ATE40140T1/de

Links

102000014654 Aromatase Human genes 0.000 title 1
108010078554 Aromatase Proteins 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
150000003431 steroids Chemical class 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
LUJVUUWNAPIQQI-QAGGRKNESA-N androsta-1,4-diene-3,17-dione Chemical class O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 LUJVUUWNAPIQQI-QAGGRKNESA-N 0.000 abstract 1
239000003886 aromatase inhibitor Substances 0.000 abstract 1
229940046844 aromatase inhibitors Drugs 0.000 abstract 1
230000001419 dependent effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
229940088597 hormone Drugs 0.000 abstract 1
239000005556 hormone Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D63/00—Flexible elongated elements, e.g. straps, for bundling or supporting articles
- B65D63/10—Non-metallic straps, tapes, or bands; Filamentary elements, e.g. strings, threads or wires; Joints between ends thereof
- B65D63/12—Joints produced by deformation or tying of ends of elements
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S383/00—Flexible bags
- Y10S383/905—Dead fold, ductile, closure element
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T24/00—Buckles, buttons, clasps, etc.
- Y10T24/15—Bag fasteners
- Y10T24/153—Plastic band bag tie
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T24/00—Buckles, buttons, clasps, etc.
- Y10T24/15—Bag fasteners
- Y10T24/157—Twist-to-close bag tie
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24008—Structurally defined web or sheet [e.g., overall dimension, etc.] including fastener for attaching to external surface
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31786—Of polyester [e.g., alkyd, etc.]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Mechanical Engineering (AREA)
Diabetes (AREA)
Hematology (AREA)
Oncology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Package Frames And Binding Bands (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)

AT86305647T 1985-08-01 1986-07-23 Aromatase inhibierende steroide. ATE40140T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858519398A GB8519398D0 (en)	1985-08-01	1985-08-01	Steroidic aromatase inhibitors
EP86305647A EP0210832B1 (de)	1985-08-01	1986-07-23	Aromatase inhibierende Steroide

Publications (1)

Publication Number	Publication Date
ATE40140T1 true ATE40140T1 (de)	1989-02-15

Family

ID=10583186

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86305647T ATE40140T1 (de)	1985-08-01	1986-07-23	Aromatase inhibierende steroide.

Country Status (20)

Country	Link
US (1)	US4771043A (de)
EP (1)	EP0210832B1 (de)
JP (1)	JPH07635B2 (de)
KR (1)	KR870002049A (de)
AT (1)	ATE40140T1 (de)
AU (1)	AU584225B2 (de)
CA (1)	CA1252085A (de)
DE (1)	DE3661833D1 (de)
DK (1)	DK164173C (de)
ES (1)	ES2001476A6 (de)
FI (1)	FI84273C (de)
GB (1)	GB8519398D0 (de)
GR (1)	GR861951B (de)
HU (1)	HU197028B (de)
IE (1)	IE60754B1 (de)
IL (1)	IL79465A0 (de)
NZ (1)	NZ216922A (de)
PT (1)	PT83061B (de)
SU (1)	SU1540656A3 (de)
ZA (1)	ZA865525B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8615092D0 (en) *	1986-06-20	1986-07-23	Erba Farmitalia	Androst-4-ene-317-diones
GB8624251D0 (en) *	1986-10-09	1986-11-12	Erba Farmitalia	"1,2-beta-methylene-4-substituted androstene-3,17 dione derivatives
JPH0655982A (ja) *	1992-08-07	1994-03-01	Ikeda Bussan Co Ltd	加飾部材付内装材
JPH0672255A (ja) *	1992-08-31	1994-03-15	Ikeda Bussan Co Ltd	加飾部材付内装材
US20040082557A1 (en) *	2001-01-26	2004-04-29	Wajszczuk Charles Paul	Methods for treating estrogen-dependent disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB892620A (en) *	1957-07-20	1962-03-28	Syntex Sa	Cyclopentanophenanthrene derivatives
GB1042291A (en) *	1961-11-08	1966-09-14	Organon Labor Ltd	í¸-6ª‡-amino steroids and the preparation thereof
GB992998A (en) *	1962-07-17	1965-05-26	Shionogi & Co	Process for preparing 5ª-hydroxy-6ª-aminosteroids of the pregnane series
US3320291A (en) *	1962-10-23	1967-05-16	Du Pont	5-fluoro-6-nitrimino-and 6-keto steroids and their preparation
US3239510A (en) *	1963-03-30	1966-03-08	Shionogi & Co	6-dialkylamino-4-pregnene-3, 20-diones
US3781276A (en) *	1972-07-11	1973-12-25	Schering Corp	6-azido-6-dehydro steroids of the progesterone series,methods for their manufacture and intermediates produced therby
US4028348A (en) *	1976-02-17	1977-06-07	Richter Gedeon Vegyeszeti Gyar Rt	6-Amino-5β,19-cycloandrostane derivatives
AU577677B2 (en) *	1986-02-25	1988-09-29	Development Finance Corporation Of New Zealand, The	Cutting apparatus

1985
- 1985-08-01 GB GB858519398A patent/GB8519398D0/en active Pending
1986
- 1986-07-18 HU HU862969A patent/HU197028B/hu not_active IP Right Cessation
- 1986-07-21 ES ES8600446A patent/ES2001476A6/es not_active Expired
- 1986-07-21 AU AU60381/86A patent/AU584225B2/en not_active Ceased
- 1986-07-21 US US06/887,438 patent/US4771043A/en not_active Expired - Fee Related
- 1986-07-21 IL IL79465A patent/IL79465A0/xx not_active IP Right Cessation
- 1986-07-22 NZ NZ216922A patent/NZ216922A/xx unknown
- 1986-07-23 AT AT86305647T patent/ATE40140T1/de not_active IP Right Cessation
- 1986-07-23 DE DE8686305647T patent/DE3661833D1/de not_active Expired
- 1986-07-23 EP EP86305647A patent/EP0210832B1/de not_active Expired
- 1986-07-24 ZA ZA865525A patent/ZA865525B/xx unknown
- 1986-07-24 DK DK352086A patent/DK164173C/da not_active IP Right Cessation
- 1986-07-24 JP JP61172925A patent/JPH07635B2/ja not_active Expired - Lifetime
- 1986-07-24 GR GR861951A patent/GR861951B/el unknown
- 1986-07-25 FI FI863068A patent/FI84273C/fi not_active IP Right Cessation
- 1986-07-25 CA CA000514647A patent/CA1252085A/en not_active Expired
- 1986-07-25 SU SU864027926A patent/SU1540656A3/ru active
- 1986-07-25 PT PT83061A patent/PT83061B/pt not_active IP Right Cessation
- 1986-07-25 IE IE197086A patent/IE60754B1/en not_active IP Right Cessation
- 1986-07-26 KR KR1019860006111A patent/KR870002049A/ko not_active Ceased

Also Published As

Publication number	Publication date
JPH07635B2 (ja)	1995-01-11
JPS6270393A (ja)	1987-03-31
FI84273B (fi)	1991-07-31
AU584225B2 (en)	1989-05-18
DK352086A (da)	1987-02-02
DE3661833D1 (de)	1989-02-23
GR861951B (en)	1986-11-25
FI84273C (fi)	1991-11-11
FI863068A0 (fi)	1986-07-25
DK164173B (da)	1992-05-18
NZ216922A (en)	1989-07-27
KR870002049A (ko)	1987-03-28
IE60754B1 (en)	1994-08-10
IE861970L (en)	1987-02-01
HUT42783A (en)	1987-08-28
US4771043A (en)	1988-09-13
PT83061B (pt)	1989-02-28
ZA865525B (en)	1987-03-25
SU1540656A3 (ru)	1990-01-30
CA1252085A (en)	1989-04-04
IL79465A0 (en)	1986-10-31
AU6038186A (en)	1987-02-05
PT83061A (en)	1986-08-01
ES2001476A6 (es)	1988-06-01
HU197028B (en)	1989-02-28
EP0210832A1 (de)	1987-02-04
DK352086D0 (da)	1986-07-24
DK164173C (da)	1992-10-12
FI863068L (fi)	1987-02-02
EP0210832B1 (de)	1989-01-18
GB8519398D0 (en)	1985-09-04

Legal Events

Date	Code	Title	Description
1989-05-15	UEP	Publication of translation of european patent specification
1996-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ES8802429A1 (es)	1988-06-01	Un procedimiento para la preparacion de androsta-1,4-dien-3,17-dionas
FI884087A0 (fi)	1988-09-06	Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion.
GB8622330D0 (en)	1986-10-22	4-substituted 6-alkylidenandrostene-3,17-dione derivatives
FI91070B (fi)	1994-01-31	Parannus androsta-1,4-dieeni-3,17-dionin 6-metyleenijohdannaisten synteesissä
DE3760277D1 (en)	1989-08-03	New 6- or 7-methylenandrosta-1, 4-diene-3,17-dione derivatives and process for their preparation
DE3873862D1 (de)	1992-09-24	17-substituierte androsta-1,4-dien-3-on-derivate.
FI865259A0 (fi)	1986-12-22	Foerfarande foer framstaellning av 10 -alkynylestrenderivat.
DK352086A (da)	1987-02-02	Steroide aromatase-inhibitorer
DK1163258T3 (da)	2003-03-31	Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis
GB1033920A (en)	1966-06-22	Novel derivatives of triphenylethanols