ATE403739T1 - Verfahren zur verwendung teilungsarretierter zellen in screening-assays - Google Patents
Verfahren zur verwendung teilungsarretierter zellen in screening-assaysInfo
- Publication number
- ATE403739T1 ATE403739T1 AT03751966T AT03751966T ATE403739T1 AT E403739 T1 ATE403739 T1 AT E403739T1 AT 03751966 T AT03751966 T AT 03751966T AT 03751966 T AT03751966 T AT 03751966T AT E403739 T1 ATE403739 T1 AT E403739T1
- Authority
- AT
- Austria
- Prior art keywords
- arrested cells
- screening assay
- division arrested
- cells
- assays
- Prior art date
Links
- 238000007423 screening assay Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000007878 drug screening assay Methods 0.000 abstract 1
- 238000012203 high throughput assay Methods 0.000 abstract 1
- 238000003567 signal transduction assay Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/251,467 US7045281B2 (en) | 2002-09-20 | 2002-09-20 | Method for using division arrested cells in screening assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE403739T1 true ATE403739T1 (de) | 2008-08-15 |
Family
ID=31992746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03751966T ATE403739T1 (de) | 2002-09-20 | 2003-09-04 | Verfahren zur verwendung teilungsarretierter zellen in screening-assays |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US7045281B2 (de) |
| EP (1) | EP1581645B1 (de) |
| JP (1) | JP4317922B2 (de) |
| AT (1) | ATE403739T1 (de) |
| AU (1) | AU2003270073B2 (de) |
| CA (1) | CA2499621A1 (de) |
| DE (1) | DE60322743D1 (de) |
| WO (1) | WO2004027374A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045281B2 (en) * | 2002-09-20 | 2006-05-16 | Cell & Molecular Technologies, Inc. | Method for using division arrested cells in screening assays |
| JP2006507817A (ja) * | 2002-10-04 | 2006-03-09 | ニューテクバイオ・リミテッド | 細胞表面タンパク質のシグナル伝達活性を活性化する分子の存在および／またはレベルを決定するための遺伝子レポーターアッセイ、キット、および細胞 |
| ES2641271T3 (es) * | 2006-10-30 | 2017-11-08 | Le Centre National De La Recherche Scientifique (Cnrs) | Ensayo de gen indicador, kit y células con sensibilidad y/o especificidad mejoradas para determinar el nivel del TNF-alfa |
| ES2409356T3 (es) * | 2007-10-30 | 2013-06-26 | Le Centre National De La Recherche Scientifique (Cnrs) | Método de realización de un ensayo para neutralizar anticuerpos |
| WO2009111572A2 (en) * | 2008-03-04 | 2009-09-11 | Le Centre Nationale De La Recherche Scientifique | Cell, method and kit for conducting an assay for neutralizing antibodies |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998136A (en) * | 1996-08-19 | 1999-12-07 | Arcaris, Inc. | Selection systems and methods for identifying genes and gene products involved in cell proliferation |
| US20010046497A1 (en) * | 2000-04-21 | 2001-11-29 | Zhang Fang Liang | G-protein coupled receptor and methods |
| US6897067B2 (en) * | 2000-11-03 | 2005-05-24 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
| EP1330516B1 (de) | 2000-11-03 | 2007-01-17 | The Regents Of The University Of Michigan | Oberflächentransfektion und expressionsverfahren |
| CA2437576A1 (en) | 2001-02-15 | 2002-08-22 | Kosan Biosciences, Inc. | Method for evaluating therapeutic efficacy |
| US6723527B2 (en) * | 2001-10-26 | 2004-04-20 | Board Of Regents, The University Of Texas System | Methods for determining toxicity reversing agents |
| US7045281B2 (en) * | 2002-09-20 | 2006-05-16 | Cell & Molecular Technologies, Inc. | Method for using division arrested cells in screening assays |
-
2002
- 2002-09-20 US US10/251,467 patent/US7045281B2/en not_active Expired - Lifetime
-
2003
- 2003-09-04 AT AT03751966T patent/ATE403739T1/de not_active IP Right Cessation
- 2003-09-04 JP JP2004537712A patent/JP4317922B2/ja not_active Expired - Fee Related
- 2003-09-04 WO PCT/US2003/027537 patent/WO2004027374A2/en not_active Ceased
- 2003-09-04 EP EP03751966A patent/EP1581645B1/de not_active Expired - Lifetime
- 2003-09-04 DE DE60322743T patent/DE60322743D1/de not_active Expired - Lifetime
- 2003-09-04 CA CA002499621A patent/CA2499621A1/en not_active Abandoned
- 2003-09-04 AU AU2003270073A patent/AU2003270073B2/en not_active Expired
-
2006
- 2006-02-27 US US11/363,983 patent/US20060148007A1/en not_active Abandoned
-
2007
- 2007-07-10 US US11/775,708 patent/US20080081327A1/en not_active Abandoned
-
2008
- 2008-06-12 US US12/138,218 patent/US20080248516A1/en not_active Abandoned
-
2010
- 2010-01-11 US US12/685,223 patent/US7960101B2/en not_active Expired - Fee Related
-
2011
- 2011-05-06 US US13/102,917 patent/US20110275101A1/en not_active Abandoned
-
2012
- 2012-05-01 US US13/461,649 patent/US20120276545A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110275101A1 (en) | 2011-11-10 |
| US20120276545A1 (en) | 2012-11-01 |
| WO2004027374A2 (en) | 2004-04-01 |
| US7045281B2 (en) | 2006-05-16 |
| US20040058329A1 (en) | 2004-03-25 |
| US20080081327A1 (en) | 2008-04-03 |
| EP1581645B1 (de) | 2008-08-06 |
| JP4317922B2 (ja) | 2009-08-19 |
| US20060148007A1 (en) | 2006-07-06 |
| EP1581645A4 (de) | 2006-11-29 |
| AU2003270073B2 (en) | 2006-09-07 |
| US20080248516A1 (en) | 2008-10-09 |
| CA2499621A1 (en) | 2004-04-01 |
| EP1581645A2 (de) | 2005-10-05 |
| WO2004027374A3 (en) | 2005-08-04 |
| US20100203561A1 (en) | 2010-08-12 |
| DE60322743D1 (de) | 2008-09-18 |
| US7960101B2 (en) | 2011-06-14 |
| AU2003270073A1 (en) | 2004-04-08 |
| JP2006500025A (ja) | 2006-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |