ATE403739T1 - Verfahren zur verwendung teilungsarretierter zellen in screening-assays - Google Patents

Verfahren zur verwendung teilungsarretierter zellen in screening-assays

Info

Publication number
ATE403739T1
ATE403739T1 AT03751966T AT03751966T ATE403739T1 AT E403739 T1 ATE403739 T1 AT E403739T1 AT 03751966 T AT03751966 T AT 03751966T AT 03751966 T AT03751966 T AT 03751966T AT E403739 T1 ATE403739 T1 AT E403739T1
Authority
AT
Austria
Prior art keywords
arrested cells
screening assay
division arrested
cells
assays
Prior art date
Application number
AT03751966T
Other languages
English (en)
Inventor
Thomas Livelli
Zhong Zhong
Mark Federici
Mei Cong
Original Assignee
Invitrogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitrogen Corp filed Critical Invitrogen Corp
Application granted granted Critical
Publication of ATE403739T1 publication Critical patent/ATE403739T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT03751966T 2002-09-20 2003-09-04 Verfahren zur verwendung teilungsarretierter zellen in screening-assays ATE403739T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/251,467 US7045281B2 (en) 2002-09-20 2002-09-20 Method for using division arrested cells in screening assays

Publications (1)

Publication Number Publication Date
ATE403739T1 true ATE403739T1 (de) 2008-08-15

Family

ID=31992746

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03751966T ATE403739T1 (de) 2002-09-20 2003-09-04 Verfahren zur verwendung teilungsarretierter zellen in screening-assays

Country Status (8)

Country Link
US (7) US7045281B2 (de)
EP (1) EP1581645B1 (de)
JP (1) JP4317922B2 (de)
AT (1) ATE403739T1 (de)
AU (1) AU2003270073B2 (de)
CA (1) CA2499621A1 (de)
DE (1) DE60322743D1 (de)
WO (1) WO2004027374A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7045281B2 (en) * 2002-09-20 2006-05-16 Cell & Molecular Technologies, Inc. Method for using division arrested cells in screening assays
DK1573016T3 (da) * 2002-10-04 2014-07-28 Biomonitor Ltd Genreporterassay, -kit og -celler.
ES2729501T3 (es) * 2006-10-30 2019-11-04 Centre Nat Rech Scient Ensayo de gen indicador, kit y células con sensibilidad y/o especificidad mejoradas para determinar el nivel del TNF-gamma
EP2220488B1 (de) * 2007-10-30 2013-01-09 Le Centre National De La Recherche Scientifique (CNRS) Verfahren zur durchführung eines tests zur neutralisierung von antikörpern
EP2262905B1 (de) * 2008-03-04 2015-02-25 Centre National De La Recherche Scientifique Zelle, verfahren und kit zur durchführung eines tests zur neutralisierung von antikörpern

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998136A (en) * 1996-08-19 1999-12-07 Arcaris, Inc. Selection systems and methods for identifying genes and gene products involved in cell proliferation
US20010046497A1 (en) * 2000-04-21 2001-11-29 Zhang Fang Liang G-protein coupled receptor and methods
EP1330516B1 (de) 2000-11-03 2007-01-17 The Regents Of The University Of Michigan Oberflächentransfektion und expressionsverfahren
US6897067B2 (en) * 2000-11-03 2005-05-24 Regents Of The University Of Michigan Surface transfection and expression procedure
EP1365726A2 (de) * 2001-02-15 2003-12-03 Kosan Biosciences, Inc. Verfahern zur beurteilung der therapeutischen wirksamkeit
US6723527B2 (en) * 2001-10-26 2004-04-20 Board Of Regents, The University Of Texas System Methods for determining toxicity reversing agents
US7045281B2 (en) * 2002-09-20 2006-05-16 Cell & Molecular Technologies, Inc. Method for using division arrested cells in screening assays

Also Published As

Publication number Publication date
US20040058329A1 (en) 2004-03-25
DE60322743D1 (de) 2008-09-18
EP1581645A4 (de) 2006-11-29
AU2003270073A1 (en) 2004-04-08
EP1581645B1 (de) 2008-08-06
US7960101B2 (en) 2011-06-14
JP4317922B2 (ja) 2009-08-19
US20100203561A1 (en) 2010-08-12
WO2004027374A3 (en) 2005-08-04
US20110275101A1 (en) 2011-11-10
EP1581645A2 (de) 2005-10-05
CA2499621A1 (en) 2004-04-01
JP2006500025A (ja) 2006-01-05
US20120276545A1 (en) 2012-11-01
WO2004027374A2 (en) 2004-04-01
US20060148007A1 (en) 2006-07-06
AU2003270073B2 (en) 2006-09-07
US20080081327A1 (en) 2008-04-03
US7045281B2 (en) 2006-05-16
US20080248516A1 (en) 2008-10-09

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