ATE403752T1 - Genetischer marker zur differenzierung von mycobakterien - Google Patents

Genetischer marker zur differenzierung von mycobakterien

Info

Publication number
ATE403752T1
ATE403752T1 AT03706832T AT03706832T ATE403752T1 AT E403752 T1 ATE403752 T1 AT E403752T1 AT 03706832 T AT03706832 T AT 03706832T AT 03706832 T AT03706832 T AT 03706832T AT E403752 T1 ATE403752 T1 AT E403752T1
Authority
AT
Austria
Prior art keywords
mycobacterium
present
mycobacteria
differentiation
genetic marker
Prior art date
Application number
AT03706832T
Other languages
English (en)
Inventor
Stewart Cole
Roland Brosch
Stephen Gordon
Karin Eiglmeier
Thierry Garnier
Original Assignee
Pasteur Institut
Veterinary Lab Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Veterinary Lab Agency filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE403752T1 publication Critical patent/ATE403752T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
AT03706832T 2002-02-25 2003-02-25 Genetischer marker zur differenzierung von mycobakterien ATE403752T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02290458A EP1338657B9 (de) 2002-02-25 2002-02-25 Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine

Publications (1)

Publication Number Publication Date
ATE403752T1 true ATE403752T1 (de) 2008-08-15

Family

ID=27635905

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02290458T ATE360097T1 (de) 2002-02-25 2002-02-25 Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine
AT03706832T ATE403752T1 (de) 2002-02-25 2003-02-25 Genetischer marker zur differenzierung von mycobakterien

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02290458T ATE360097T1 (de) 2002-02-25 2002-02-25 Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine

Country Status (12)

Country Link
US (1) US7977047B2 (de)
EP (2) EP1338657B9 (de)
JP (1) JP4738740B2 (de)
AT (2) ATE360097T1 (de)
AU (1) AU2003208539B2 (de)
CA (1) CA2477195C (de)
CY (1) CY1106584T1 (de)
DE (2) DE60219589T2 (de)
DK (1) DK1338657T3 (de)
ES (1) ES2286212T3 (de)
PT (1) PT1338657E (de)
WO (1) WO2003070981A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914299B9 (de) 2002-04-05 2012-05-02 Institut Pasteur Identifizierung der Virulenz-assoziierten Region RD1, die die Entwicklung von verbesserten Impstoffen mit M. microti ermöglicht
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
GB0406271D0 (en) * 2004-03-19 2004-04-21 Isis Innovation Diagnostic test
ES2375406T3 (es) 2004-04-26 2012-02-29 Wako Pure Chemical Industries, Ltd. Sonda y cebador para la detección de bacilos tuberculosos, y procedimiento para la detección de bacilos tuberculosos humanos con el uso de los mismos.
AU2005336287B2 (en) * 2005-09-05 2012-02-02 Bio-Rad Innovations Use of both RD9 and IS6110 as nucleic acid targets for the diagnosis of tuberculosis, and provision of multiplex-compliant IS6110 and RD9 targets
BRPI0604958B1 (pt) * 2006-11-23 2022-05-17 Fundação Oswaldo Cruz Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg
WO2010132112A2 (en) 2009-05-14 2010-11-18 Wisconsin Alumni Research Foundation Immunogenic compositions against tuberculosis
KR101498705B1 (ko) * 2010-07-02 2015-03-06 (주)바이오니아 결핵 진단용 프라이머, 프로브, 이를 포함하는 키트 및 상기 키트를 이용한 결핵 진단 방법
JP2013055947A (ja) * 2012-10-26 2013-03-28 Bio-Rad Innovations 結核の診断のための核酸標的としてのrd9およびis6110の使用、ならびにマルチプレックス−コンプライアントis6110およびrd9標的の提供
RU2697502C2 (ru) * 2014-07-24 2019-08-14 Эбботт Молекьюлар Инк. Композиции и способы обнаружения и анализа микобактерии туберкулеза (mycobacterium tuberculosis)
WO2017156436A1 (en) * 2016-03-11 2017-09-14 S&R Pharmaceuticals, Llc Assays and methods for detecting mycobacterial infections
CN106868113A (zh) * 2017-01-24 2017-06-20 中国疾病预防控制中心传染病预防控制所 用于鉴定牛型结核分枝杆菌的snp标记及其应用
US20240218457A1 (en) * 2021-05-03 2024-07-04 The Board Of Trustees Of The Leland Stanford Junior University Method for diagnosing active tuberculosis and progression to active tuberculosis
KR20220164261A (ko) 2021-06-04 2022-12-13 (주)아모레퍼시픽 단백질 분해효소 안정성 증진용 조성물, 이를 포함하는 동결건조 조성물, 이를 포함하는 화장품 키트, 및 이의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5714593A (en) * 1995-02-01 1998-02-03 Institut Pasteur DNA from mycobacterium tuberculosis which codes for a 45/47 kilodalton protein
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
FR2791067B1 (fr) * 1999-03-16 2003-01-31 Pasteur Institut Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins
AU5559300A (en) * 1999-07-06 2001-01-22 Institut Pasteur Method of making and identifying attenuated microorganisms, compositions utilizing the sequences responsible for attenuation, and preparations containing attenuated microorganisms

Also Published As

Publication number Publication date
JP2005518203A (ja) 2005-06-23
ES2286212T3 (es) 2007-12-01
EP1338657A1 (de) 2003-08-27
AU2003208539A1 (en) 2003-09-09
EP1338657B9 (de) 2007-10-10
PT1338657E (pt) 2007-06-21
US20060127897A1 (en) 2006-06-15
WO2003070981A2 (en) 2003-08-28
ATE360097T1 (de) 2007-05-15
DK1338657T3 (da) 2007-07-30
DE60219589D1 (de) 2007-05-31
EP1478777A2 (de) 2004-11-24
CA2477195A1 (en) 2003-08-28
EP1338657B1 (de) 2007-04-18
EP1478777B1 (de) 2008-08-06
CA2477195C (en) 2015-01-06
DE60219589T2 (de) 2008-02-14
US7977047B2 (en) 2011-07-12
WO2003070981A8 (en) 2004-10-07
WO2003070981A3 (en) 2003-12-04
DE60322674D1 (de) 2008-09-18
AU2003208539B2 (en) 2008-11-20
JP4738740B2 (ja) 2011-08-03
CY1106584T1 (el) 2012-01-25

Similar Documents

Publication Publication Date Title
DE60322674D1 (de) Genetischer Marker zur Differenzierung von Mycobakterien
Jagielski et al. Current methods in the molecular typing of Mycobacterium tuberculosis and other mycobacteria
ES2157230T3 (es) Deteccion de mycobacteria por amplificacion multiple de acidos nucleicos.
Vasylyeva Identification of Bordetella bronchiseptica bacteria with the help of polymerase chain reaction in monoand multyplex format
CY1109210T1 (el) Διαγραφεισες αλληλουχιες στο μ. bovis bcg/m. bovis ΄η μ. tuberculosis, μεθοδος ανιχνευσεως μυκοβακτηριων που χρησιμοποιουν αυτες τις αλληλουχιες και εμβολια
ATE534749T1 (de) Sonde und primer zum nachweis von tuberkelbazillen sowie verfahren zum nachweis von tuberkelbazillen beim menschen damit
Hughes et al. Molecular analyses of mycobacteria other than the M. tuberculosis complex isolated from Northern Ireland cattle
WO2005075673A3 (en) Detection, identification and differentiation of proteus species using the spacer region
WO2007011367A3 (en) Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16s ribosomal rna gene and identification of bacterial species by amplicon sequencing
Slany A new cultivation‐independent tool for fast and reliable detection of M ycobacterium marinum
ATE431432T1 (de) Verfahren zum nachweis von mycobacterium tuberculosis
DE60327462D1 (de) Nachweis, identifizierung und differenzierung von eubakterien unter verwendung eines hybridisierungs-assays
Jeon et al. Variable number tandem repeat analysis of Mycobacterium bovis isolates from Gyeonggi-do, Korea
WO2011090875A3 (en) Primers, sequences and recombinant probes for identification of mycobacterium species
ATE548465T1 (de) Diagnoseverfahren und dafür geeignete produkte
ATE518964T1 (de) Verfahren und kit zum spezifischen nachweis von m. tuberculosis
WO2007034118A8 (fr) Procede de detection, dans un echantillon biologique de mycobacteries, et en particulier de mycobacteries caracteristiques de la tuberculose
EP1044282A1 (de) Eine methode zur diagnose, identifizierung und charakterisierung von m. tuberculosis und anderer mycobakterien durch einen mobilitäts shift assay
ATE486138T1 (de) Verfahren zum nachweis von bakterien der gattung mycobacterium (säureresistente bakterien)
DE602005022094D1 (de) Nukleinsäuresequenzen, die sich als primer und sonden bei der amplifikation und dem nachweis von hsv-dna verwenden lassen, sowie verfahren zur amplifikation und zum nachweis von hsv-dna unter einsatz einer amplifikation auf transkriptionsbasis
FR2857375B1 (fr) Procede de detection et/ou d'identification de bacteries de genre staphylococcus
ATE446386T1 (de) Verfahren zur überwachung genomischer dna von organismen
US20030219778A1 (en) Method for the diagnosis, identification and characterization of M. tuberculosis and other mycobacteria by shift mobility assay
Parthiban et al. Characterization of Pnca Gene Responsible for Pyrazinamidase Enzyme in Mycobacterium tuberculosis Clinical Isolate
WO2005085478A3 (en) Detection and identification of mycobacterium and nocardia using primers and probes directed to the seca1 gene

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties