ATE360097T1 - Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine - Google Patents

Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine

Info

Publication number
ATE360097T1
ATE360097T1 AT02290458T AT02290458T ATE360097T1 AT E360097 T1 ATE360097 T1 AT E360097T1 AT 02290458 T AT02290458 T AT 02290458T AT 02290458 T AT02290458 T AT 02290458T AT E360097 T1 ATE360097 T1 AT E360097T1
Authority
AT
Austria
Prior art keywords
mycobacterium
vaccines
diagnostics
mycobacterium tuberculosis
sequences specifically
Prior art date
Application number
AT02290458T
Other languages
English (en)
Inventor
Stewart Cole
Roland Brosch
Stephen Glyn Hewinson Gordon
Karin Eiglmeier
Thierry Garnier
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE360097T1 publication Critical patent/ATE360097T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
AT02290458T 2002-02-25 2002-02-25 Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine ATE360097T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02290458A EP1338657B9 (de) 2002-02-25 2002-02-25 Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine

Publications (1)

Publication Number Publication Date
ATE360097T1 true ATE360097T1 (de) 2007-05-15

Family

ID=27635905

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02290458T ATE360097T1 (de) 2002-02-25 2002-02-25 Spezifisch vom genom von mycobacterium tuberculosis deletierte sequenzen und deren verwendung in der diagnostik und als vakzine
AT03706832T ATE403752T1 (de) 2002-02-25 2003-02-25 Genetischer marker zur differenzierung von mycobakterien

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03706832T ATE403752T1 (de) 2002-02-25 2003-02-25 Genetischer marker zur differenzierung von mycobakterien

Country Status (12)

Country Link
US (1) US7977047B2 (de)
EP (2) EP1338657B9 (de)
JP (1) JP4738740B2 (de)
AT (2) ATE360097T1 (de)
AU (1) AU2003208539B2 (de)
CA (1) CA2477195C (de)
CY (1) CY1106584T1 (de)
DE (2) DE60219589T2 (de)
DK (1) DK1338657T3 (de)
ES (1) ES2286212T3 (de)
PT (1) PT1338657E (de)
WO (1) WO2003070981A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914299B9 (de) 2002-04-05 2012-05-02 Institut Pasteur Identifizierung der Virulenz-assoziierten Region RD1, die die Entwicklung von verbesserten Impstoffen mit M. microti ermöglicht
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
GB0406271D0 (en) * 2004-03-19 2004-04-21 Isis Innovation Diagnostic test
ES2375406T3 (es) 2004-04-26 2012-02-29 Wako Pure Chemical Industries, Ltd. Sonda y cebador para la detección de bacilos tuberculosos, y procedimiento para la detección de bacilos tuberculosos humanos con el uso de los mismos.
AU2005336287B2 (en) * 2005-09-05 2012-02-02 Bio-Rad Innovations Use of both RD9 and IS6110 as nucleic acid targets for the diagnosis of tuberculosis, and provision of multiplex-compliant IS6110 and RD9 targets
BRPI0604958B1 (pt) * 2006-11-23 2022-05-17 Fundação Oswaldo Cruz Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg
WO2010132112A2 (en) 2009-05-14 2010-11-18 Wisconsin Alumni Research Foundation Immunogenic compositions against tuberculosis
KR101498705B1 (ko) * 2010-07-02 2015-03-06 (주)바이오니아 결핵 진단용 프라이머, 프로브, 이를 포함하는 키트 및 상기 키트를 이용한 결핵 진단 방법
JP2013055947A (ja) * 2012-10-26 2013-03-28 Bio-Rad Innovations 結核の診断のための核酸標的としてのｒｄ９およびｉｓ６１１０の使用、ならびにマルチプレックス−コンプライアントｉｓ６１１０およびｒｄ９標的の提供
RU2697502C2 (ru) * 2014-07-24 2019-08-14 Эбботт Молекьюлар Инк. Композиции и способы обнаружения и анализа микобактерии туберкулеза (mycobacterium tuberculosis)
WO2017156436A1 (en) * 2016-03-11 2017-09-14 S&R Pharmaceuticals, Llc Assays and methods for detecting mycobacterial infections
CN106868113A (zh) * 2017-01-24 2017-06-20 中国疾病预防控制中心传染病预防控制所 用于鉴定牛型结核分枝杆菌的snp标记及其应用
US20240218457A1 (en) * 2021-05-03 2024-07-04 The Board Of Trustees Of The Leland Stanford Junior University Method for diagnosing active tuberculosis and progression to active tuberculosis
KR20220164261A (ko) 2021-06-04 2022-12-13 (주)아모레퍼시픽 단백질 분해효소 안정성 증진용 조성물, 이를 포함하는 동결건조 조성물, 이를 포함하는 화장품 키트, 및 이의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5714593A (en) * 1995-02-01 1998-02-03 Institut Pasteur DNA from mycobacterium tuberculosis which codes for a 45/47 kilodalton protein
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
FR2791067B1 (fr) * 1999-03-16 2003-01-31 Pasteur Institut Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins
AU5559300A (en) * 1999-07-06 2001-01-22 Institut Pasteur Method of making and identifying attenuated microorganisms, compositions utilizing the sequences responsible for attenuation, and preparations containing attenuated microorganisms

Also Published As

Publication number Publication date
JP2005518203A (ja) 2005-06-23
ES2286212T3 (es) 2007-12-01
EP1338657A1 (de) 2003-08-27
AU2003208539A1 (en) 2003-09-09
EP1338657B9 (de) 2007-10-10
PT1338657E (pt) 2007-06-21
US20060127897A1 (en) 2006-06-15
WO2003070981A2 (en) 2003-08-28
ATE403752T1 (de) 2008-08-15
DK1338657T3 (da) 2007-07-30
DE60219589D1 (de) 2007-05-31
EP1478777A2 (de) 2004-11-24
CA2477195A1 (en) 2003-08-28
EP1338657B1 (de) 2007-04-18
EP1478777B1 (de) 2008-08-06
CA2477195C (en) 2015-01-06
DE60219589T2 (de) 2008-02-14
US7977047B2 (en) 2011-07-12
WO2003070981A8 (en) 2004-10-07
WO2003070981A3 (en) 2003-12-04
DE60322674D1 (de) 2008-09-18
AU2003208539B2 (en) 2008-11-20
JP4738740B2 (ja) 2011-08-03
CY1106584T1 (el) 2012-01-25

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