ATE404551T1 - 3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung - Google Patents

3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung

Info

Publication number: ATE404551T1
Authority: AT; Austria
Prior art keywords: group; carbons; hydroxymethylbenzo; production; trihalomethoxy
Prior art date: 2001-05-07

Application number

AT02724673T

Other languages

English (en)

Inventor

Hirosi Saitou

Tsuyoshi Mizuno

Naoki Tsuchiya

Original Assignee

Teijin Pharma Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-07

Filing date

2002-05-02

Publication date

2008-08-15

2002-05-02 Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE404551T1 publication Critical patent/ATE404551T1/de

Links

YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000004951 trihalomethoxy group Chemical group 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 abstract 1
150000003462 sulfoxides Chemical class 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
125000004953 trihalomethyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

AT02724673T 2001-05-07 2002-05-02 3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung ATE404551T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2001135928		2001-05-07

Publications (1)

Publication Number	Publication Date
ATE404551T1 true ATE404551T1 (de)	2008-08-15

Family

ID=18983308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02724673T ATE404551T1 (de)	2001-05-07	2002-05-02	3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung

Country Status (13)

Country	Link
US (1)	US6774245B2 (de)
EP (1)	EP1298130B1 (de)
JP (1)	JP3999131B2 (de)
KR (1)	KR20030031486A (de)
CN (1)	CN1205204C (de)
AT (1)	ATE404551T1 (de)
CA (1)	CA2414298A1 (de)
DE (1)	DE60228182D1 (de)
HK (1)	HK1052352B (de)
NO (1)	NO20030058L (de)
NZ (1)	NZ523407A (de)
PL (1)	PL358478A1 (de)
WO (1)	WO2002090345A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ522150A (en) *	2001-02-22	2006-03-31	Teijin Ltd	Benzo[b]thiophene derivatives and processes for preparing the same
CL2004001034A1 (es) *	2003-05-14	2005-03-28	Teijin Pharma Ltd	Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r
AU2004266536A1 (en) *	2003-08-22	2005-03-03	Teijin Pharma Limited	Drug containing chymase inhibitor as the active ingredient
US20080015240A1 (en) *	2004-11-12	2008-01-17	Mitsuru Teramoto	Acid Salt of Benzimidazole Derivative and Crystal Thereof
JPWO2007049812A1 (ja)	2005-10-27	2009-04-30	帝人ファーマ株式会社	３−ヒドロキシメチルベンゾ［ｂ］チオフェン誘導体およびその製造方法
JP2007145827A (ja)	2005-10-27	2007-06-14	Teijin Pharma Ltd	ベンゾ［ｂ］チオフェン誘導体およびその製造方法
CN102850246B (zh) *	2012-07-10	2015-04-22	江西理工大学	一种苯胺类衍生物引入巯基的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL343316A1 (en) *	1998-03-31	2001-08-13	Shionogi & Co	Process for producing 5-hydroxybenzo[b]thiophene-3-carboxylic acid derivatives
PT1249450E (pt)	2000-01-17	2008-01-02	Teijin Pharma Ltd	Derivados de benzimidazole como inibidores de quimase humana

2002
- 2002-05-02 AT AT02724673T patent/ATE404551T1/de not_active IP Right Cessation
- 2002-05-02 CN CNB02801541XA patent/CN1205204C/zh not_active Expired - Fee Related
- 2002-05-02 HK HK03104594.9A patent/HK1052352B/en not_active IP Right Cessation
- 2002-05-02 NZ NZ523407A patent/NZ523407A/en unknown
- 2002-05-02 US US10/332,079 patent/US6774245B2/en not_active Expired - Fee Related
- 2002-05-02 CA CA002414298A patent/CA2414298A1/en not_active Abandoned
- 2002-05-02 WO PCT/JP2002/004383 patent/WO2002090345A1/ja not_active Ceased
- 2002-05-02 PL PL02358478A patent/PL358478A1/xx not_active Application Discontinuation
- 2002-05-02 EP EP02724673A patent/EP1298130B1/de not_active Expired - Lifetime
- 2002-05-02 JP JP2002587425A patent/JP3999131B2/ja not_active Expired - Fee Related
- 2002-05-02 KR KR1020027015842A patent/KR20030031486A/ko not_active Ceased
- 2002-05-02 DE DE60228182T patent/DE60228182D1/de not_active Expired - Fee Related
2003
- 2003-01-06 NO NO20030058A patent/NO20030058L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1298130A1 (de)	2003-04-02
HK1052352A1 (en)	2003-09-11
EP1298130B1 (de)	2008-08-13
HK1052352B (en)	2008-11-07
CA2414298A1 (en)	2002-12-30
CN1462271A (zh)	2003-12-17
US20030191325A1 (en)	2003-10-09
NO20030058D0 (no)	2003-01-06
NZ523407A (en)	2005-04-29
KR20030031486A (ko)	2003-04-21
JPWO2002090345A1 (ja)	2004-08-26
AU2002255294C1 (en)	2002-11-18
PL358478A1 (en)	2004-08-09
DE60228182D1 (de)	2008-09-25
JP3999131B2 (ja)	2007-10-31
WO2002090345A1 (fr)	2002-11-14
CN1205204C (zh)	2005-06-08
EP1298130A4 (de)	2005-03-30
US6774245B2 (en)	2004-08-10
NO20030058L (no)	2003-03-05

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Legal Events

Date	Code	Title	Description
2009-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties