ATE404554T1 - Pyrimidinderivate zur verwendung als antikrebsmittel - Google Patents

Pyrimidinderivate zur verwendung als antikrebsmittel

Info

Publication number: ATE404554T1
Authority: AT; Austria
Prior art keywords: anticancer agents; pyrimidine derivatives; substituents; man; text
Prior art date: 2005-04-05

Application number

AT06726601T

Other languages

English (en)

Inventor

Andrew Peter Thomas

Thorsten Nowak

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-05

Filing date

2006-03-31

Publication date

2008-08-15

2005-04-05 Priority claimed from GB0506883A external-priority patent/GB0506883D0/en

2005-12-21 Priority claimed from GB0525953A external-priority patent/GB0525953D0/en

2006-03-31 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE404554T1 publication Critical patent/ATE404554T1/de

Links

CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
239000002246 antineoplastic agent Substances 0.000 title 1
229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
102100039688 Insulin-like growth factor 1 receptor Human genes 0.000 abstract 1
101710184277 Insulin-like growth factor 1 receptor Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT06726601T 2005-04-05 2006-03-31 Pyrimidinderivate zur verwendung als antikrebsmittel ATE404554T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0506883A GB0506883D0 (en)	2005-04-05	2005-04-05	Chemical compounds
GB0525953A GB0525953D0 (en)	2005-12-21	2005-12-21	Chemical compounds

Publications (1)

Publication Number	Publication Date
ATE404554T1 true ATE404554T1 (de)	2008-08-15

Family

ID=36641343

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06726601T ATE404554T1 (de)	2005-04-05	2006-03-31	Pyrimidinderivate zur verwendung als antikrebsmittel

Country Status (18)

Country	Link
US (1)	US20080167297A1 (de)
EP (1)	EP1869032B8 (de)
JP (1)	JP2008534662A (de)
KR (1)	KR20070116994A (de)
AT (1)	ATE404554T1 (de)
AU (1)	AU2006231116A1 (de)
BR (1)	BRPI0609965A2 (de)
CA (1)	CA2602372A1 (de)
DE (1)	DE602006002271D1 (de)
DK (1)	DK1869032T3 (de)
ES (1)	ES2310406T3 (de)
HR (1)	HRP20080505T3 (de)
IL (1)	IL186034A0 (de)
MX (1)	MX2007012345A (de)
NO (1)	NO20074869L (de)
PT (1)	PT1869032E (de)
SI (1)	SI1869032T1 (de)
WO (1)	WO2006106307A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010111050A1 (en) *	2009-03-23	2010-09-30	Banyu Pharmaceutical Co., Ltd.	Novel aminopyridine derivatives having aurora a selective inhibitory action
AU2010229140A1 (en) *	2009-03-24	2011-11-10	Msd K.K.	Novel aminopyridine derivatives having Aurora A selective inhibitory action
US20110053916A1 (en) *	2009-08-14	2011-03-03	Vertex Pharmaceuticals Incorporated	Pyrimidine compounds as tuberculosis inhibitors
CA2845578C (en) *	2011-08-25	2016-02-16	Merck Sharp & Dohme Corp.	Pyrimidine pde10 inhibitors
WO2023163712A1 (en) *	2022-02-25	2023-08-31	Nalo Therapeutics	Modulators of myc family proto-oncogene protein
US20250170130A1 (en) *	2022-02-25	2025-05-29	Nalo Therapeutics	Modulators of myc family proto-oncogene protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2426180A1 (de) *	1974-05-29	1975-12-18	Bayer Ag	Verfahren zum faerben von polyurethankunststoffen
AU2001290912A1 (en) *	2000-09-15	2002-03-26	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
BR0116493A (pt) *	2000-12-21	2003-09-30	Vertex Pharma	Compostos de pirazol úteis como inibidores de proteìna cinase
US6939874B2 (en) *	2001-08-22	2005-09-06	Amgen Inc.	Substituted pyrimidinyl derivatives and methods of use
DK2316831T3 (da) *	2002-11-21	2013-06-10	Novartis Ag	2-(Morpholin-4-yl)pyrimidiner som phosphotidylinositol (PI)-3-kinaseinhibitorer samt deres anvendelse ved behandling af cancer
ES2328820T3 (es) *	2003-10-17	2009-11-18	Astrazeneca Ab	Derivados de 4-(pirazol-3-ilamino)pirimidina para uso en el tratamiento de cancer.

2006
- 2006-03-31 HR HR20080505T patent/HRP20080505T3/xx unknown
- 2006-03-31 US US11/909,940 patent/US20080167297A1/en not_active Abandoned
- 2006-03-31 ES ES06726601T patent/ES2310406T3/es not_active Expired - Lifetime
- 2006-03-31 JP JP2008504835A patent/JP2008534662A/ja active Pending
- 2006-03-31 MX MX2007012345A patent/MX2007012345A/es not_active Application Discontinuation
- 2006-03-31 BR BRPI0609965-3A patent/BRPI0609965A2/pt not_active IP Right Cessation
- 2006-03-31 PT PT06726601T patent/PT1869032E/pt unknown
- 2006-03-31 AT AT06726601T patent/ATE404554T1/de not_active IP Right Cessation
- 2006-03-31 KR KR1020077025674A patent/KR20070116994A/ko not_active Withdrawn
- 2006-03-31 DE DE602006002271T patent/DE602006002271D1/de not_active Expired - Fee Related
- 2006-03-31 DK DK06726601T patent/DK1869032T3/da active
- 2006-03-31 SI SI200630088T patent/SI1869032T1/sl unknown
- 2006-03-31 EP EP06726601A patent/EP1869032B8/de not_active Expired - Lifetime
- 2006-03-31 AU AU2006231116A patent/AU2006231116A1/en not_active Abandoned
- 2006-03-31 WO PCT/GB2006/001195 patent/WO2006106307A1/en not_active Ceased
- 2006-03-31 CA CA002602372A patent/CA2602372A1/en not_active Abandoned
2007
- 2007-09-18 IL IL186034A patent/IL186034A0/en unknown
- 2007-09-25 NO NO20074869A patent/NO20074869L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2310406T3 (es)	2009-01-01
EP1869032A1 (de)	2007-12-26
DE602006002271D1 (de)	2008-09-25
HRP20080505T3 (hr)	2008-11-30
AU2006231116A1 (en)	2006-10-12
SI1869032T1 (sl)	2008-12-31
MX2007012345A (es)	2007-11-23
JP2008534662A (ja)	2008-08-28
EP1869032B1 (de)	2008-08-13
WO2006106307A1 (en)	2006-10-12
US20080167297A1 (en)	2008-07-10
EP1869032B8 (de)	2009-03-25
NO20074869L (no)	2007-11-02
DK1869032T3 (da)	2008-11-10
CA2602372A1 (en)	2006-10-12
KR20070116994A (ko)	2007-12-11
HK1114387A1 (en)	2008-10-31
IL186034A0 (en)	2008-02-09
BRPI0609965A2 (pt)	2011-10-11
PT1869032E (pt)	2008-10-21

Legal Events

Date

Code

Title

Description

2009-02-15

UEP

Publication of translation of european patent specification

Ref document number: 1869032

Country of ref document: EP

2011-12-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
TN2010000101A1 (en)	2011-09-26	Fungicidal 2-alkylthio-2-quinolinyloxy -acetamide derivatives
MX2009009774A (es)	2009-09-23	Derivados de quinolina como fungicidas.
TN2010000102A1 (en)	2011-09-26	Novel fungicides
UA96314C2 (ru)	2011-10-25	Замещенные 1-(3-пиридинил)пиразол-4-илуксусные кислоты и их применение в качестве гербицидов и регуляторов роста растений
TW200637853A (en)	2006-11-01	Fungicides
NO20054856D0 (no)	2005-10-20	4-anilo-kinazolinderivater som antiproliferative midler
TW200800956A (en)	2008-01-01	2-Aminopyrimidine derivatives
ATE544760T1 (de)	2012-02-15	Heterocyclische hydrazidverbindung und ihre verwendung als pestizid
TW200734303A (en)	2007-09-16	Organic compounds
TW200618800A (en)	2006-06-16	Heterocyclic compounds
TN2010000064A1 (en)	2011-09-26	Novel herbicides
MX2010001364A (es)	2010-03-01	Derivados de ciclopentandiona puenteados triciclicos como herbicidas.
TW200637837A (en)	2006-11-01	Fungicides
GB0412769D0 (en)	2004-07-07	Organic compounds
NO20062130L (no)	2006-05-12	4-(pyrazol-3-ylamino)pyrimidinderivater for anvendelse i behandling av kreft
UA101963C2 (en)	2013-05-27	4-amino-pyrimidine derivatives
TW200728277A (en)	2007-08-01	Bicyclic derivatives as P38 inhibitors
MX2007000392A (es)	2007-06-15	Derivados de 2-pirrolidona sustituida como fungicidas e insecticidas.
GB0508318D0 (en)	2005-06-01	Organic compounds
IL186034A0 (en)	2008-02-09	Pyrimidine derivatives for use as anticancer agents
NO20081207L (no)	2008-05-27	Isoquinolines as IGF-1R inhibitors
TW200613251A (en)	2006-05-01	Organic compounds
MY159479A (en)	2017-01-13	Herbicides
DE602005007064D1 (de)	2008-07-03	Chromanderivate und ihre verwendung als liganden des 5-ht-rezeptors
GB0508715D0 (en)	2005-06-08	Chemical compounds