ATE404637T1 - Verbessertes verfahren und methode zur herstellung von asymmetrischen monofunktionalisierten indocyaninmarkern sowie erhaltene verbindungen - Google Patents

Verbessertes verfahren und methode zur herstellung von asymmetrischen monofunktionalisierten indocyaninmarkern sowie erhaltene verbindungen

Info

Publication number
ATE404637T1
ATE404637T1 AT01127884T AT01127884T ATE404637T1 AT E404637 T1 ATE404637 T1 AT E404637T1 AT 01127884 T AT01127884 T AT 01127884T AT 01127884 T AT01127884 T AT 01127884T AT E404637 T1 ATE404637 T1 AT E404637T1
Authority
AT
Austria
Prior art keywords
indolenine
indocyanine
monofunctionalized
markers
improved process
Prior art date
Application number
AT01127884T
Other languages
English (en)
Inventor
Giuseppe Caputo
Ciana Leopoldo Della
Original Assignee
Visen Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visen Medical Inc filed Critical Visen Medical Inc
Application granted granted Critical
Publication of ATE404637T1 publication Critical patent/ATE404637T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
AT01127884T 2000-11-28 2001-11-23 Verbessertes verfahren und methode zur herstellung von asymmetrischen monofunktionalisierten indocyaninmarkern sowie erhaltene verbindungen ATE404637T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00126019A EP1209205A1 (de) 2000-11-28 2000-11-28 Verbesserte Verfahren und Methode zur Herstellung von asymmetrischen monofunktionalisierten Indocyaninmarkern sowie erhaltene Verbindungen

Publications (1)

Publication Number Publication Date
ATE404637T1 true ATE404637T1 (de) 2008-08-15

Family

ID=8170514

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01127884T ATE404637T1 (de) 2000-11-28 2001-11-23 Verbessertes verfahren und methode zur herstellung von asymmetrischen monofunktionalisierten indocyaninmarkern sowie erhaltene verbindungen

Country Status (7)

Country Link
US (2) US6740755B2 (de)
EP (1) EP1209205A1 (de)
AT (1) ATE404637T1 (de)
AU (1) AU783884B2 (de)
CA (1) CA2363896A1 (de)
DE (1) DE60135296D1 (de)
ES (1) ES2312393T3 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10046215B4 (de) * 2000-09-19 2004-04-15 Institut für Chemo- und Biosensorik Münster e.V. i.Ins. Fluorochrome und deren Verwendung
CA2423806C (en) * 2000-09-29 2009-12-22 Molecular Probes, Inc. Modified carbocyanine dyes and their conjugates
ATE536993T1 (de) * 2002-01-02 2011-12-15 Visen Medical Inc Aminfunktionalisierte superparamagnetisierte nanoteilchen für die synthese von biokonjugaten
WO2003079015A1 (en) * 2002-03-11 2003-09-25 Visen Medical, Inc. Optical imaging probes
ITPZ20030002A1 (it) * 2003-08-12 2005-02-13 Giuseppe Caputo Composti del tipo cianina aventi un braccio di legame alchinilico
US7705150B2 (en) 2004-02-04 2010-04-27 Biosearch Technologies, Inc. Cyanine dyes
US8227621B2 (en) * 2005-06-30 2012-07-24 Li-Cor, Inc. Cyanine dyes and methods of use
FR2889700B1 (fr) * 2005-08-11 2012-11-23 Synthinnove Lab Marqueurs, leur procede de fabrication et leurs applications
US7947256B2 (en) * 2005-09-02 2011-05-24 Visen Medical, Inc. Biocompatible fluorescent imaging agents
CA2621137C (en) * 2005-09-02 2014-07-29 Visen Medical, Inc. Biocompatible n,n-disubstituted sulfonamide-containing fluorescent dye labels
EP1934202B1 (de) * 2005-09-02 2019-01-09 Visen Medical, Inc. Nah-infrarot-fluorophore, die sich von nicotinsäure und picolinsäure ableiten
WO2007136413A2 (en) 2005-12-22 2007-11-29 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
US8221721B2 (en) * 2007-02-09 2012-07-17 Visen Medical, Inc. Polycyclo dyes and use thereof
WO2008109832A2 (en) * 2007-03-08 2008-09-12 Visen Medical, Inc. Viable near-infrared fluorochrome labeled cells and methods of making and using same
US8815214B2 (en) * 2008-01-18 2014-08-26 Visen Medical, Inc. Fluorescent imaging agents
US8864821B2 (en) 2008-11-26 2014-10-21 Visen Medical, Inc. Methods and compositions for identifying subjects at risk of developing stent thrombosis
CN103687854A (zh) 2011-05-09 2014-03-26 文森医学公司 碳酸酐酶靶向剂及其使用方法
EP2734645A4 (de) 2011-07-18 2014-12-17 Univ Georgia State Res Found Carbocyanine zur g-quadruplex-dna-stabilisierung und telomerase-hemmung
US9375493B2 (en) 2012-03-30 2016-06-28 Visen Medical, Inc. Bacterial imaging agents and methods of using same
CN104955484B (zh) 2012-08-15 2019-01-15 文森医学公司 用于前列腺癌成像的前列腺特异性抗原药剂及其使用方法
WO2014144702A2 (en) 2013-03-15 2014-09-18 Visen Medical, Inc. 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof
CA2901379C (en) 2013-03-15 2023-05-16 Visen Medical, Inc. Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection
KR101720288B1 (ko) * 2016-05-11 2017-03-28 (주)바이오액츠 뇌 영상용 염료 및 이의 제조방법
CN110885570B (zh) * 2019-12-16 2021-05-25 常州工程职业技术学院 一种近红外染料的制备方法
WO2022191485A1 (ko) 2021-03-10 2022-09-15 에스에프씨 주식회사 리포터 및 이의 용도
CN116239893B (zh) * 2023-03-21 2024-07-09 大连理工大学 一种季铵盐修饰的花菁类荧光染料及其合成方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB355693A (en) 1930-02-24 1931-08-24 Ici Ltd Manufacture of intermediates and dyes from heterocyclic nitrogen compounds
IT1276833B1 (it) * 1995-10-09 1997-11-03 Sorin Biomedica Cardio Spa Coloranti fluorescenti della famiglia della solfo benz e indocianina
DE19921234B4 (de) * 1999-05-07 2005-07-28 Few Chemicals Gmbh Cyanin-Farbstoffe

Also Published As

Publication number Publication date
EP1209205A1 (de) 2002-05-29
AU9344001A (en) 2002-06-06
ES2312393T3 (es) 2009-03-01
US20050245734A1 (en) 2005-11-03
AU783884B2 (en) 2005-12-22
US6740755B2 (en) 2004-05-25
US20020065421A1 (en) 2002-05-30
DE60135296D1 (de) 2008-09-25
CA2363896A1 (en) 2002-05-28

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