ATE370131T1 - Verfahren zur herstellung von 5-(1,3-oxazol-2- yl)benzoesäurederivaten - Google Patents

Verfahren zur herstellung von 5-(1,3-oxazol-2- yl)benzoesäurederivaten

Info

Publication number: ATE370131T1
Authority: AT; Austria
Prior art keywords: sub; oxazole; producing; benzoic acid; acid derivatives
Prior art date: 2002-06-20

Application number

AT03761206T

Other languages

English (en)

Inventor

Michael Reeder

Rick Imbordino

Original Assignee

Pharmacia & Upjohn Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-20

Filing date

2003-06-20

Publication date

2007-09-15

2003-06-20 Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE370131T1 publication Critical patent/ATE370131T1/de

Links

IMAITKPPSLYKDS-UHFFFAOYSA-N 3-(1,3-oxazol-2-yl)benzoic acid Chemical class OC(=O)C1=CC=CC(C=2OC=CN=2)=C1 IMAITKPPSLYKDS-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 5
238000000034 method Methods 0.000 abstract 2
JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical group [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
150000002916 oxazoles Chemical class 0.000 abstract 1
235000005074 zinc chloride Nutrition 0.000 abstract 1
239000011592 zinc chloride Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Psychiatry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Catalysts (AREA)

AT03761206T 2002-06-20 2003-06-20 Verfahren zur herstellung von 5-(1,3-oxazol-2- yl)benzoesäurederivaten ATE370131T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US39028502P	2002-06-20	2002-06-20
US45047803P	2003-02-27	2003-02-27

Publications (1)

Publication Number	Publication Date
ATE370131T1 true ATE370131T1 (de)	2007-09-15

Family

ID=30003150

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03761206T ATE370131T1 (de)	2002-06-20	2003-06-20	Verfahren zur herstellung von 5-(1,3-oxazol-2- yl)benzoesäurederivaten

Country Status (17)

Country	Link
US (2)	US7115747B2 (de)
EP (1)	EP1532123B1 (de)
JP (1)	JP2005533811A (de)
CN (1)	CN1324017C (de)
AT (1)	ATE370131T1 (de)
AU (1)	AU2003249344A1 (de)
BR (1)	BR0312439A (de)
CA (1)	CA2489988A1 (de)
CO (1)	CO5670350A2 (de)
DE (1)	DE60315664D1 (de)
EA (1)	EA008389B1 (de)
IL (1)	IL165763A0 (de)
MX (1)	MXPA04012630A (de)
NO (1)	NO20045497L (de)
NZ (1)	NZ537390A (de)
PL (1)	PL374999A1 (de)
WO (1)	WO2004000821A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006508166A (ja) *	2002-11-27	2006-03-09	イーランファーマスーティカルズ、インコーポレイテッド	置換尿素及びカルバメート
TW200738701A (en) *	2005-07-26	2007-10-16	Du Pont	Fungicidal carboxamides
US7745484B2 (en) *	2005-11-21	2010-06-29	Amgen Inc.	Beta-secretase modulators and methods of use
US7872009B2 (en)	2005-11-21	2011-01-18	Amgen Inc.	Beta-Secretase modulators and methods of use
US7838676B2 (en) *	2005-11-21	2010-11-23	Amgen Inc.	Beta-secretase modulators and methods of use
JP5274258B2 (ja)	2005-11-21	2013-08-28	アムジエン・インコーポレーテツド	β−セクレターゼ調節物質及び使用方法
WO2008137954A2 (en) *	2007-05-07	2008-11-13	Environmental Packaging Technologies Limited	Universal shipping container
WO2008147547A1 (en)	2007-05-25	2008-12-04	Amgen Inc.	Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use
JP5440984B2 (ja)	2007-05-25	2014-03-12	アムジエン・インコーポレーテツド	β−セクレターゼ修飾剤としての置換ヒドロキシエチルアミン化合物および使用方法
US7803809B2 (en)	2008-11-12	2010-09-28	Amgen Inc.	Substituted pyrano [2,3-b] pyridinamine compounds as beta-secretase modulators and methods of use
CA2736130C (en)	2008-09-11	2014-01-14	Amgen Inc.	Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use
WO2011063272A1 (en)	2009-11-23	2011-05-26	Amgen Inc.	Amino heteroaryl compounds as beta-secretase modulators and methods of use
EP2504315A1 (de)	2009-11-23	2012-10-03	Amgen Inc.	Aminoheteroarylverbindungen als beta-sekretase-modulatoren und verwendungsverfahren dafür
US8735384B2 (en)	2010-01-19	2014-05-27	Amgen Inc.	Amino heteroaryl compounds as beta-secretase modulators and methods of use
AU2011227501B9 (en)	2010-03-15	2013-08-22	Amgen Inc.	Amino -dihydrooxazine and amino - dihydrothiazine spiro compounds as Beta - secretase modulators and their medical use
WO2011115938A1 (en)	2010-03-15	2011-09-22	Amgen Inc.	Spiro-tetracyclic ring compounds as beta - secretase modulators
US9346827B2 (en)	2011-02-07	2016-05-24	Amgen Inc.	5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use
US9296759B2 (en)	2011-09-21	2016-03-29	Amgen Inc.	Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use
WO2014078314A1 (en)	2012-11-15	2014-05-22	Amgen Inc.	Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use
US11272751B2 (en)	2016-03-01	2022-03-15	Nicholas Popejoy	Protective headgear, impact diffusing systems and methods
US9462841B1 (en)	2016-03-01	2016-10-11	William Popejoy	Protective headgear and shoulder pad apparatus and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PE20020276A1 (es) *	2000-06-30	2002-04-06	Elan Pharm Inc	COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
US7244755B2 (en) *	2001-10-04	2007-07-17	Pharmacia & Upjohn Company	Hydroxypropylamines
RS50504A (sr) *	2001-11-08	2007-04-10	Elan Pharmaceuticals Inc.,	Derivati n,n'-supstituisanog-1,3- diamino-2-hidroksipropana
GB0325830D0 (en) *	2003-11-05	2003-12-10	Novartis Ag	Organic compounds

2003
- 2003-06-20 DE DE60315664T patent/DE60315664D1/de not_active Expired - Lifetime
- 2003-06-20 AT AT03761206T patent/ATE370131T1/de not_active IP Right Cessation
- 2003-06-20 WO PCT/US2003/019585 patent/WO2004000821A1/en not_active Ceased
- 2003-06-20 PL PL03374999A patent/PL374999A1/xx unknown
- 2003-06-20 AU AU2003249344A patent/AU2003249344A1/en not_active Abandoned
- 2003-06-20 BR BR0312439-8A patent/BR0312439A/pt not_active IP Right Cessation
- 2003-06-20 MX MXPA04012630A patent/MXPA04012630A/es active IP Right Grant
- 2003-06-20 US US10/600,100 patent/US7115747B2/en not_active Expired - Fee Related
- 2003-06-20 NZ NZ537390A patent/NZ537390A/en unknown
- 2003-06-20 CN CNB038144476A patent/CN1324017C/zh not_active Expired - Fee Related
- 2003-06-20 EP EP03761206A patent/EP1532123B1/de not_active Expired - Lifetime
- 2003-06-20 JP JP2004516055A patent/JP2005533811A/ja active Pending
- 2003-06-20 CA CA002489988A patent/CA2489988A1/en not_active Abandoned
- 2003-06-20 EA EA200401510A patent/EA008389B1/ru unknown
2004
- 2004-12-14 IL IL16576304A patent/IL165763A0/xx unknown
- 2004-12-16 NO NO20045497A patent/NO20045497L/no not_active Application Discontinuation
2005
- 2005-01-20 CO CO05004558A patent/CO5670350A2/es not_active Application Discontinuation
2006
- 2006-10-03 US US11/538,155 patent/US20070105921A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO20045497L (no)	2005-03-07
EP1532123A1 (de)	2005-05-25
WO2004000821A1 (en)	2003-12-31
US7115747B2 (en)	2006-10-03
CN1324017C (zh)	2007-07-04
US20070105921A1 (en)	2007-05-10
EA008389B1 (ru)	2007-04-27
NO20045497D0 (no)	2004-12-16
CN1662510A (zh)	2005-08-31
JP2005533811A (ja)	2005-11-10
EP1532123B1 (de)	2007-08-15
CA2489988A1 (en)	2003-12-31
CO5670350A2 (es)	2006-08-31
EA200401510A1 (ru)	2005-06-30
PL374999A1 (en)	2005-11-14
BR0312439A (pt)	2005-05-10
DE60315664D1 (de)	2007-09-27
MXPA04012630A (es)	2005-09-30
AU2003249344A1 (en)	2004-01-06
IL165763A0 (en)	2006-01-15
US20040063965A1 (en)	2004-04-01
HK1081543A1 (zh)	2006-05-19
NZ537390A (en)	2006-07-28

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Legal Events

Date	Code	Title	Description
2008-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties