ATE404969T1 - Räumlich hochaufgelöstes erzeugen einer dauerhaften struktur - Google Patents

Räumlich hochaufgelöstes erzeugen einer dauerhaften struktur

Info

Publication number
ATE404969T1
ATE404969T1 AT04726458T AT04726458T ATE404969T1 AT E404969 T1 ATE404969 T1 AT E404969T1 AT 04726458 T AT04726458 T AT 04726458T AT 04726458 T AT04726458 T AT 04726458T AT E404969 T1 ATE404969 T1 AT E404969T1
Authority
AT
Austria
Prior art keywords
switch over
over signal
substance
state
spatial resolution
Prior art date
Application number
AT04726458T
Other languages
English (en)
Inventor
Stefan Hell
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10325459A external-priority patent/DE10325459A1/de
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE404969T1 publication Critical patent/ATE404969T1/de

Links

Classifications

    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B7/00Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
    • G11B7/004Recording, reproducing or erasing methods; Read, write or erase circuits therefor
    • G11B7/0045Recording
    • G11B7/00455Recording involving reflectivity, absorption or colour changes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/16Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • GPHYSICS
    • G02OPTICS
    • G02FOPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/01Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour 
    • G02F1/0126Opto-optical modulation, i.e. control of one light beam by another light beam, not otherwise provided for in this subclass
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/04Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/04Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam
    • G11C13/041Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam using photochromic storage elements
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B7/00Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
    • G11B7/24Record carriers characterised by shape, structure or physical properties, or by the selection of the material
    • G11B7/2403Layers; Shape, structure or physical properties thereof
    • G11B7/24035Recording layers
    • G11B7/24044Recording layers for storing optical interference patterns, e.g. holograms; for storing data in three dimensions [3D], e.g. volume storage
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B7/00Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
    • G11B7/24Record carriers characterised by shape, structure or physical properties, or by the selection of the material
    • G11B7/241Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material
    • G11B7/242Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers
    • G11B7/244Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only
    • G11B7/246Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only containing dyes
    • G11B7/2467Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only containing dyes azo-dyes

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nonlinear Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Microscoopes, Condenser (AREA)
  • Optical Integrated Circuits (AREA)
AT04726458T 2003-04-13 2004-04-08 Räumlich hochaufgelöstes erzeugen einer dauerhaften struktur ATE404969T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10317613 2003-04-13
US10/420,896 US7064824B2 (en) 2003-04-13 2003-04-22 High spatial resoulution imaging and modification of structures
DE10325459A DE10325459A1 (de) 2003-04-13 2003-06-05 Räumlich hochaufgelöstes Erzeugen einer dauerhaften Struktur

Publications (1)

Publication Number Publication Date
ATE404969T1 true ATE404969T1 (de) 2008-08-15

Family

ID=33298574

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04726458T ATE404969T1 (de) 2003-04-13 2004-04-08 Räumlich hochaufgelöstes erzeugen einer dauerhaften struktur

Country Status (3)

Country Link
US (1) US7064824B2 (de)
AT (1) ATE404969T1 (de)
DE (1) DE502004007840D1 (de)

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WO2006078857A2 (en) * 2005-01-16 2006-07-27 Baer Stephen C Single wavelength stimulated emission depletion microscopy
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JP4709278B2 (ja) * 2005-05-23 2011-06-22 エフ. ヘスス ハラルド 光変換可能な光学標識を用いる光学顕微鏡法
EP1907826B2 (de) 2005-07-22 2020-11-25 Carl Zeiss MicroImaging GmbH Auflösungsgesteigerte lumineszenz-mikroskopie
WO2007030835A2 (en) * 2005-09-10 2007-03-15 Baer Stephen C High resolution microscopy using an optically switchable fluorophore
DE102006009830B4 (de) * 2006-03-01 2019-06-13 Leica Microsystems Cms Gmbh Verfahren zur räumlich hochauflösenden Untersuchung von Proben
US7679741B2 (en) * 2006-03-01 2010-03-16 Leica Microsystems Cms Gmbh Method and microscope for high spatial resolution examination of samples
DE102006062823B4 (de) * 2006-03-01 2010-11-25 Leica Microsystems Cms Gmbh Verfahren und Mikroskop zur räumlich hochauflösenden Untersuchung von Proben
DE102006021317B3 (de) * 2006-05-06 2007-10-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Fluoreszenzlichtmikroskop zum räumlich hochauflösenden Abbilden einer Struktur einer Probe
DE102006026203A1 (de) * 2006-05-31 2007-12-06 Carl Zeiss Microimaging Gmbh Verfahren zum räumlich hochauflösenden Abbilden
DE102006026204A1 (de) * 2006-05-31 2007-12-06 Carl Zeiss Microimaging Gmbh Mikroskop mit erhöhter Auflösung
DE102006060180B9 (de) * 2006-12-18 2013-08-08 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Vorrichtung zum räumlich hochaufgelösten Abbilden einer mit einer Substanz markierten Struktur
US7924432B2 (en) * 2006-12-21 2011-04-12 Howard Hughes Medical Institute Three-dimensional interferometric microscopy
US7916304B2 (en) * 2006-12-21 2011-03-29 Howard Hughes Medical Institute Systems and methods for 3-dimensional interferometric microscopy
US8217992B2 (en) * 2007-01-11 2012-07-10 The Jackson Laboratory Microscopic imaging techniques
DE102007011305A1 (de) 2007-03-06 2008-09-11 Leica Microsystems Cms Gmbh Vorrichtung und Verfahren zur Strahljustage in einem optischen Strahlengang
DE102007033737A1 (de) * 2007-07-18 2009-01-22 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Bestimmen eines Messwerts auf der Basis von Einzelmolekülereignissen
DE102007048135B4 (de) * 2007-10-05 2012-02-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Fluoreszenzlichtmikroskopisches Messen einer Probe mit rotverschobenen Stokes-Linien
DE112009000171A5 (de) 2008-02-12 2011-02-10 Dodt, Hans-Ulrich, Prof. Dr. Vorrichtung zum optischen Abbilden einer Probe
EP2107363B1 (de) * 2008-03-31 2012-07-11 Deutsches Krebsforschungszentrum Verfahren zur fluoreszenz-mikroskopischen Abbildung einer Struktur in einer Probe mit hoher dreidimensionaler räumlicher Auflösung
US7772569B2 (en) * 2008-04-01 2010-08-10 The Jackson Laboratory 3D biplane microscopy
EP2291641B2 (de) 2008-05-21 2021-02-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Bildgebung einer bestimmten struktur in einer probe mit hoher räumlicher auflösung
US8174692B2 (en) * 2008-05-21 2012-05-08 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. High spatial resolution imaging of a structure of interest in a specimen
DE102008049886B4 (de) * 2008-09-30 2021-11-04 Carl Zeiss Microscopy Gmbh Vorrichtung, insbesondere ein Mikroskop, zur Untersuchung von Proben
EP2438555B1 (de) 2009-06-02 2017-03-08 Sofast GmbH Statistische Schwankungsanalyse für hochaufgelöste Abbildungen (SOFI)
US8547533B2 (en) 2009-12-28 2013-10-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Composite probes and use thereof in super resolution methods
FR2966258B1 (fr) * 2010-10-15 2013-05-03 Bioaxial Système de microscopie de superresolution de fluorescence et méthode pour des applications biologiques
EP2535755A1 (de) 2011-06-14 2012-12-19 Ecole Polytechnique Fédérale de Lausanne (EPFL) Kumulantmikroskopie
US9664614B2 (en) * 2011-07-11 2017-05-30 University Of Limerick Method for high resolution sum-frequency generation and infrared microscopy
DE102011108181B4 (de) * 2011-07-22 2015-02-26 Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Wirtschaft und Technologie, dieses vertreten durch den Präsidenten der Physikalisch-Technischen Bundesanstalt Verfahren zum ortsaufgelösten Messen einer Magnetisierung einer magnetischen Struktur und magnetooptischer Datenspeicher
JP5854680B2 (ja) * 2011-07-25 2016-02-09 キヤノン株式会社 撮像装置
EP2831497B1 (de) 2012-03-29 2025-05-07 École Polytechnique Fédérale de Lausanne (EPFL) Verfahren und vorrichtung für bildgebung mit multimodalen glasfasern
JP6335160B2 (ja) 2012-04-13 2018-05-30 バイオアキシアル エスエーエス 光学測定方法および光学測定装置
DE102013100172A1 (de) * 2013-01-09 2014-07-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum räumlich hochaufgelösten Abbilden einer einen Luminophor aufweisenden Struktur einer Probe
US10921255B2 (en) 2014-12-09 2021-02-16 Bioaxial Sas Optical measuring device and process
DE102015116435A1 (de) 2015-09-29 2017-03-30 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Spektralbereiche
DE102015121920A1 (de) 2015-12-16 2017-06-22 Carl Zeiss Microscopy Gmbh Hochauflösendes Kurzzeit-Mikroskopieverfahren und hochauflösendes Kurzzeit-Mikroskop
DE102017113683A1 (de) 2017-06-21 2018-12-27 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Wellenlängenbereiche
CN117795319A (zh) * 2021-07-26 2024-03-29 马克斯-普朗克科学促进学会 通过在分子周围连续移动聚焦光束来定位单一化的荧光团分子

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Also Published As

Publication number Publication date
DE502004007840D1 (de) 2008-09-25
US7064824B2 (en) 2006-06-20
US20040212799A1 (en) 2004-10-28

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