ATE405297T1 - Para-hydrogen markierte mittel und deren verwendung zur bilderzeugung durch nicht-proton magnetische resonanz - Google Patents

Para-hydrogen markierte mittel und deren verwendung zur bilderzeugung durch nicht-proton magnetische resonanz

Info

Publication number
ATE405297T1
ATE405297T1 AT98952931T AT98952931T ATE405297T1 AT E405297 T1 ATE405297 T1 AT E405297T1 AT 98952931 T AT98952931 T AT 98952931T AT 98952931 T AT98952931 T AT 98952931T AT E405297 T1 ATE405297 T1 AT E405297T1
Authority
AT
Austria
Prior art keywords
magnetic resonance
sample
imaging agent
hydrogen
nuclear spin
Prior art date
Application number
AT98952931T
Other languages
English (en)
Inventor
Klaes Golman
Oskar Axelsson
Haukur Johanneson
Charlotte Olofsson
Sven Mansson
Stefan Petersson
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9723920.6A external-priority patent/GB9723920D0/en
Priority claimed from GBGB9800158.9A external-priority patent/GB9800158D0/en
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE405297T1 publication Critical patent/ATE405297T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98952931T 1997-11-12 1998-11-12 Para-hydrogen markierte mittel und deren verwendung zur bilderzeugung durch nicht-proton magnetische resonanz ATE405297T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9723920.6A GB9723920D0 (en) 1997-11-12 1997-11-12 Method
GBGB9800158.9A GB9800158D0 (en) 1998-01-05 1998-01-05 Method

Publications (1)

Publication Number Publication Date
ATE405297T1 true ATE405297T1 (de) 2008-09-15

Family

ID=26312589

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98952931T ATE405297T1 (de) 1997-11-12 1998-11-12 Para-hydrogen markierte mittel und deren verwendung zur bilderzeugung durch nicht-proton magnetische resonanz

Country Status (11)

Country Link
US (2) US6574495B1 (de)
EP (1) EP1047455B1 (de)
JP (1) JP2001522819A (de)
KR (1) KR100600670B1 (de)
CN (1) CN100571787C (de)
AT (1) ATE405297T1 (de)
AU (1) AU1047399A (de)
DE (1) DE69839924D1 (de)
NO (1) NO320225B1 (de)
RU (1) RU2218182C2 (de)
WO (1) WO1999024080A1 (de)

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Also Published As

Publication number Publication date
CN1306441A (zh) 2001-08-01
NO20002429D0 (no) 2000-05-10
KR20010024606A (ko) 2001-03-26
EP1047455A1 (de) 2000-11-02
JP2001522819A (ja) 2001-11-20
WO1999024080A1 (en) 1999-05-20
EP1047455B1 (de) 2008-08-20
RU2218182C2 (ru) 2003-12-10
AU1047399A (en) 1999-05-31
US6574495B1 (en) 2003-06-03
US20040024307A1 (en) 2004-02-05
NO320225B1 (no) 2005-11-14
NO20002429L (no) 2000-05-10
CN100571787C (zh) 2009-12-23
DE69839924D1 (de) 2008-10-02
KR100600670B1 (ko) 2006-07-13

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