ATE405651T1 - Zu vegf und bmp1 homologe polypeptide - Google Patents
Zu vegf und bmp1 homologe polypeptideInfo
- Publication number
- ATE405651T1 ATE405651T1 AT99912362T AT99912362T ATE405651T1 AT E405651 T1 ATE405651 T1 AT E405651T1 AT 99912362 T AT99912362 T AT 99912362T AT 99912362 T AT99912362 T AT 99912362T AT E405651 T1 ATE405651 T1 AT E405651T1
- Authority
- AT
- Austria
- Prior art keywords
- vegf
- bmp1
- growth factor
- vascular endothelial
- endothelial growth
- Prior art date
Links
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 title abstract 5
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 title abstract 5
- 102000004152 Bone morphogenetic protein 1 Human genes 0.000 title abstract 2
- 108090000654 Bone morphogenetic protein 1 Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003511 endothelial effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
- 230000037314 wound repair Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/040,220 US6391311B1 (en) | 1998-03-17 | 1998-03-17 | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
| US18421698A | 1998-11-02 | 1998-11-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405651T1 true ATE405651T1 (de) | 2008-09-15 |
Family
ID=26716852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99912362T ATE405651T1 (de) | 1998-03-17 | 1999-03-10 | Zu vegf und bmp1 homologe polypeptide |
Country Status (13)
| Country | Link |
|---|---|
| US (11) | US6455283B1 (de) |
| EP (2) | EP1064382B1 (de) |
| JP (3) | JP4532733B2 (de) |
| AT (1) | ATE405651T1 (de) |
| AU (1) | AU758353B2 (de) |
| CA (1) | CA2322792C (de) |
| CY (2) | CY1108500T1 (de) |
| DE (1) | DE69939374D1 (de) |
| DK (2) | DK1064382T3 (de) |
| ES (2) | ES2389387T3 (de) |
| IL (5) | IL138488A0 (de) |
| PT (1) | PT2016951E (de) |
| WO (1) | WO1999047677A2 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000053760A2 (en) * | 1999-03-12 | 2000-09-14 | Genentech, Inc. | Method of preventing the death of retinal neurons and treating ocular diseases |
| EP1053317B1 (de) | 1998-02-13 | 2006-11-02 | Köster, Hubert | Verwendung von ribozymen zur bestimmung der funktion von genen |
| AU759086B2 (en) * | 1998-03-06 | 2003-04-03 | Crosscart, Inc. | Soft tissue xenografts |
| PT2016951E (pt) | 1998-03-17 | 2012-09-27 | Genentech Inc | Polipéptidos homólogos de vegf e de bmp1 |
| EP0984063A3 (de) * | 1998-08-31 | 2000-08-16 | Eli Lilly And Company | Vegf-verwandtes gen und protein |
| AU764039B2 (en) * | 1998-12-07 | 2003-08-07 | Zymogenetics Inc. | Growth factor homolog ZVEGF3 |
| US6432673B1 (en) | 1998-12-07 | 2002-08-13 | Zymogenetics, Inc. | Growth factor homolog ZVEGF3 |
| US6663870B2 (en) | 1998-12-07 | 2003-12-16 | Zymogenetics, Inc. | Methods for promoting growth of bone using zvegf3 |
| DE69936733T2 (de) * | 1998-12-22 | 2008-06-05 | Janssen Pharmaceutica N.V. | Vaskulärer endothelialer wachstumsfaktor x |
| US6783953B1 (en) | 1998-12-22 | 2004-08-31 | Janssen Pharmaceutica N.V. | Vascular endothelial growth factor-X |
| AU2486300A (en) * | 1998-12-30 | 2000-07-31 | Millennium Pharmaceuticals, Inc. | Secreted proteins and nucleic acids encoding them |
| CA2362427A1 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| WO2000059940A2 (en) * | 1999-04-06 | 2000-10-12 | Eli Lilly And Company | Platelet-derived growth factor related gene and protein |
| US6630142B2 (en) | 1999-05-03 | 2003-10-07 | Zymogenetics, Inc. | Method of treating fibroproliferative disorders |
| AU7868000A (en) * | 1999-10-07 | 2001-05-10 | Curagen Corporation | Growth factor polypeptides and nucleic acids encoding same |
| WO2001028586A1 (en) * | 1999-10-21 | 2001-04-26 | Zymogenetics, Inc. | Method of treating fibrosis |
| US6893637B1 (en) * | 1999-10-21 | 2005-05-17 | Zymogenetics, Inc. | Method of treating fibrosis |
| WO2001032197A2 (en) * | 1999-11-02 | 2001-05-10 | Eli Lilly And Company | Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders |
| EP1252308A2 (de) * | 2000-01-19 | 2002-10-30 | Parkash S. Gill | Pharmazeutische zubereitungen und behandlungsmethoden, die auf vegf antisense-oligonucleotiden basieren |
| US7141607B1 (en) | 2000-03-10 | 2006-11-28 | Insite Vision Incorporated | Methods and compositions for treating and inhibiting retinal neovascularization |
| EP1267627A1 (de) * | 2000-03-28 | 2003-01-02 | Ludwig Institute For Cancer Research | Nicht-menschliche transgenische tiere die von blutplättchen abstammender wachstumsfaktor c (pdgf-c) exprimeren und deren verwendung |
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| US7166280B2 (en) * | 2000-04-06 | 2007-01-23 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic heart disease |
| US20070111935A1 (en) * | 2000-04-06 | 2007-05-17 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs |
| WO2001077328A1 (en) * | 2000-04-06 | 2001-10-18 | Franco Wayne P | Methods of using growth factors for treating heart disease |
| CA2654413C (en) * | 2000-04-12 | 2016-10-18 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Use of vegf and homologues to treat neuron disorders |
| EP1297016B1 (de) * | 2000-05-12 | 2006-03-22 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Verwendung von inhibitoren des plazenta wachstumsfactors für die behandlung einer pathologischen angiogenese, pathologischen arteriogenese, entzündung, tumorbildung und/oder gefässdurchlässigkeit (ödem) |
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| US20020091082A1 (en) * | 2000-09-13 | 2002-07-11 | Aiello Lloyd P. | Methods of modulating symptoms of hypertension |
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| EP1341914A2 (de) | 2000-12-07 | 2003-09-10 | Sangamo Biosciences Inc. | Regulation der angiogenese durch zinkfinger-proteine |
| US7067317B2 (en) | 2000-12-07 | 2006-06-27 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
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| KR20030081402A (ko) | 2001-03-09 | 2003-10-17 | 얀센 파마슈티카 엔.브이. | Vegf-x 또는 그의 길항제에 의한 평활근 세포 증식의조절 |
| US6913762B2 (en) * | 2001-04-25 | 2005-07-05 | Mayo Foundation For Medical Education And Research | Stent having non-woven framework containing cells |
| US7981863B2 (en) | 2001-09-19 | 2011-07-19 | Neuronova Ab | Treatment of Parkinson's disease with PDGF |
| AU2002366641A1 (en) * | 2001-12-11 | 2003-06-23 | Fibrogen, Inc. | Methods for inhibiting ocular processes |
| WO2003092665A2 (en) * | 2002-05-02 | 2003-11-13 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
| CA2483142A1 (en) * | 2002-05-06 | 2003-11-20 | Genentech, Inc. | Use of vegf for treating bone defects |
| AU2003245935A1 (en) * | 2002-06-13 | 2003-12-31 | Novuspharma S.P.A. | Derivatives of chromen-2-one as inhibitors of vegf production in mammalian cells |
| US20040052161A1 (en) * | 2002-09-17 | 2004-03-18 | Steven Liao | Mechanical clock having wireless manipulation and adjustment function |
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| US20060024302A1 (en) * | 2004-03-05 | 2006-02-02 | Ludwig Institute For Cancer Research | Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same |
| WO2005087812A1 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for vegf/pdgf family of growth factors |
| US8415315B2 (en) | 2004-05-06 | 2013-04-09 | University Of Central Florida Research Foundation, Inc. | Methods and compositions for inhibiting the proliferation of cancer cells |
| RS51481B (sr) | 2004-05-27 | 2011-04-30 | Vib, Vzw | Lečenje amiotrofične lateralne skleroze |
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| CN101184776B (zh) | 2005-03-24 | 2013-04-24 | 斯路姆基因公司 | 新型抗胎盘生长因子抗体 |
| DE602006020881D1 (de) | 2005-08-15 | 2011-05-05 | Vegenics Pty Ltd | Enen eigenschaften |
| DK2548578T3 (da) | 2006-05-17 | 2014-10-06 | Ludwig Inst Cancer Res | Målretning af VEGF-B-regulering af fedtsyretransportører til modulering af humane sygdomme |
| ES2354922B1 (es) | 2009-09-02 | 2012-02-07 | Fundacion Institut De Recerca De L'hospital Universitari Vall D'hebron | Marcadores para la selección de terapias personalizadas para el tratamiento del c�?ncer. |
| TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| EA018848B1 (ru) * | 2010-10-20 | 2013-11-29 | Вадим Юльевич ШАНИН | Иммунологически активное вещество, способ его получения, биозонд на его основе и способ диагностики состояния здоровья с применением биозонда, фармацевтическая композиция и способ лечения с использованием фармацевтической композиции |
| EP2785739B1 (de) | 2011-12-01 | 2017-03-15 | ThromboGenics N.V. | Verbesserung eines augendrucksenkungsergebnisses |
| NZ700274A (en) | 2012-04-24 | 2016-10-28 | Thrombogenics Nv | Anti-pdgf-c antibodies |
| CA2873881A1 (en) * | 2012-05-18 | 2013-11-21 | Stephen Bruce Fleming | Combination treatments and compositions for wound healing |
| WO2014159813A1 (en) | 2013-03-13 | 2014-10-02 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| CN105713095B (zh) * | 2016-03-14 | 2021-05-07 | 南京安吉生物科技有限公司 | 一种多功能融合多肽及其制备方法和应用 |
| KR101943081B1 (ko) | 2017-08-31 | 2019-01-29 | (주)케어젠 | 주름 개선 활성을 나타내는 펩타이드 및 이의 용도 |
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